ColinASieffMD
Pediatric Hematology & Oncology • Boston, MAAssociate Professor, Pediatrics, Children's Hospital, Harvard Medical School
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Office
300 Longwood Ave
Boston, MA 02115Phone+1 617-258-5228Fax+1 617-258-6768- Is this information wrong?
Education & Training
University of the WitwatersrandClass of 1968
Certifications & Licensure
MA State Medical License 1990 - 2023
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 1988
Clinical Trials
- Safety and Efficacy Trial of Danazol in Patients With Fanconi Anemia or Dyskeratosis Congenita Start of enrollment: 2009 Nov 01
- Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia Start of enrollment: 2013 Jun 01
Publications & Presentations
PubMed
- 5 citationsA Grammastola spatulata mechanotoxin-4 (GsMTx4)-sensitive cation channel mediates increased cation permeability in human hereditary spherocytosis of multiple genetic e...David H. Vandorpe, Boris E. Shmukler, Yann Ilboudo, Swati S. Bhasin, Beena E Thomas, Alicia Rivera, Jay Wohlgemuth, Jeffrey S. Dlott, L. Michael Snyder, Colin A. Sieff...> ;Haematologica. 2021 Jun 10
- 12 citationsL-leucine improves anemia and growth in patients with transfusion-dependent Diamond-Blackfan anemia: Results from a multicenter pilot phase I/II study from the Diamond...Adrianna Vlachos, Evangelia Atsidaftos, Mohammad Lutfi Lababidi, Ellen Muir, Zora R. Rogers, Waseem Alhushki, Jonathan Bernstein, Bertil Glader, Barbara Gruner, Helge ...> ;Pediatric Blood & Cancer. 2020 Dec 1
- 21 citationsTGF-β signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond syndromeCailin E. Joyce, Assieh Saadatpour, Melisa Ruiz-Gutierrez, Özge Vargel Bölükbaşı, Lan Jiang, Dolly D. Thomas, Sarah Young, Inga Hofmann, Colin A. Sieff, Kasiani C. Mye...> ;The Journal of Clinical Investigation. 2019 Sep 3
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Journal Articles
- The Phenotypic Spectrum of Germline YARS2 Variants: From Isolated Sideroblastic Anemia to Mitochondrial Myopathy, Lactic Acidosis and Sideroblastic Anemia 2Matthew M Heeney, Gregory A Hale, David P Steensma, Mark D Fleming, Colin A Sieff, Lee M Hilliard, Sylvia S Bottomley, Janet L Kwiatkowski, Haematologica
Other
- Recombinant hematopoietic growth factors in inherited bone marrow failure syndromesSieff CA
http://www.uptodate.com/contents/recombinant-hematopoietic-growth-factors-in-inherited-bone-marrow-f
UpToDate, Wolters Kluwer Health - 2012-06-22 - Introduction to recombinant hematopoietic growth factorsSieff CA
http://www.uptodate.com/contents/introduction-to-recombinant-hematopoietic-growth-factors
UpToDate, Wolters Kluwer Health - 2012-04-24 - Overview of hematopoiesis and stem cell functionSieff CA
http://www.uptodate.com/contents/overview-of-hematopoiesis-and-stem-cell-function
UpToDate, Wolters Kluwer Health - 2012-04-19 - Join now to see all
Grant Support
- Developmental Biology Of Human HematopoiesisNational Center For Research Resources2004
- Genetic Heterogeneity And Protein Function In DBANational Heart, Lung, And Blood Institute2001–2003
- Correction Of RPS 19 Defects In Diamond Blackfan AnemiaNational Heart, Lung, And Blood Institute2000–2002
- Transplant Biology, Gene Transfer, And Stem Cell SourcesNational Heart, Lung, And Blood Institute1995–1998
- Sources And Actions Of GM-CSF And Multi-CsfNational Cancer Institute1994–1995
- The Sources And Actions Of Human GM-CSF And Multi-CsfNational Cancer Institute1991–1993
- Human Immunodeficiency Virus And HematopoiesisNational Institute Of Diabetes And Digestive And Kidney Diseases1989–1993
- Sources And Actions Of Human GM-CSF And Multi-CsfNational Cancer Institute1992
- Sources And Actions Of Human Gmcsf And Multi-CsfNational Cancer Institute1987–1989
Hospital Affiliations
Dana-Farber Cancer InstituteBoston, Massachusetts
Boston Children's HospitalBoston, Massachusetts
Brigham and Women's HospitalBoston, Massachusetts
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