ConnieLCelumMD

Infectious Disease • Seattle, WA

Professor, Global Health and Community Medicine, University of Washington School of Medicine

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Office
325 9th Ave
Seattle, WA 98104
Phone+1 206-744-3000
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Education & Training

University of WashingtonFellowship, Infectious Disease, 1989 - 1991
University of California San Francisco School of MedicineClass of 1984, MD

Certifications & Licensure

CA State Medical License 1985 - Present
WA State Medical License 1987 - 2024
American Board of Internal Medicine Internal Medicine

Clinical Trials

A Study of the Effects of Advantage 24 on the Rectum
Completed
Phase 1
A Study of HIV in Newly Infected Individuals
Completed
A Study to Monitor the Health of Participants in HIVNET 014 Who Become Infected With HIV-1 Start of enrollment: 1999 Aug 01
Completed
Effects of BufferGel and PRO 2000/5 Gel in Men
Completed
Phase 1
HIV and Genital Herpes Among High-Risk Men Who Have Sex With Men (MSM) in Lima, Peru
Completed
A Study of Patients Who Develop HIV Infection After Enrolling in HIV Vaccine Trials or HIV Vaccine Preparedness Trials Start of enrollment: 2002 Apr 01
Completed
A Study of Acyclovir to Help Prevent HIV Infection in People With Genital Herpes Start of enrollment: 2005 Apr 01
Completed
Phase 3
Herpes Simplex Virus Type 2 (HSV-2) Suppression to Prevent HIV Transmission Start of enrollment: 2004 Nov 01
Completed
Phase 3
Effectiveness of Acyclovir in Suppressing HIV Viral Load in Women Coinfected With HIV and Herpes Simplex Virus Type 2 (HSV-2) Start of enrollment: 2006 Sep 01
Completed
Phase 2
HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1, HSV-2 Co-infected Men. Start of enrollment: 2003 Aug 01
Completed
Phase 3
HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1 Co-infected Persons Start of enrollment: 2005 Jan 01
Completed
Phase 3
Pre-Exposure Prophylaxis to Prevent HIV-1 Acquisition Within HIV-1 Discordant Couples Start of enrollment: 2008 May 01
Completed
Phase 3
GUD Clinical and Virologic Response to Acyclovir in HIV Negative African Women Start of enrollment: 2009 Jan 01
Completed
Not Applicable
Valacyclovir vs. Acyclovir as HSV-2 Suppressive Therapy: Effect on Plasma HIV-1 Levels Among HIV-1/HSV-2 Co-infected Persons Start of enrollment: 2010 Feb 01
Completed
Phase 4
Strategies to Increase HIV Testing, Linkages to Care, and Male Circumcision in Africa Start of enrollment: 2013 Jun 01
Completed
Not Applicable
Uptake and Adherence to Daily Oral PrEP as a Primary Prevention Strategy for Young African Women: A Vanguard Study Start of enrollment: 2016 Oct 12
Completed
Phase 4
HIV Self Testing of Male Partners of Women in PMTCT Start of enrollment: 2018 May 17
Completed
Not Applicable
The Prevention Options for Women Evaluation Research (POWER) Cohort Start of enrollment: 2017 Jun 14
Completed
The PrEP (Pre-exposure Prophylaxis) SMART Study Start of enrollment: 2019 May 16
Completed
Not Applicable
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Publications & Presentations

PubMed

High study participation but diverging adherence levels: qualitatively unpacking PrEP use among adolescent girls and young women over two years in Eastern Cape, South ...
Emily Krogstad Mudzingwa, Lindsey de Vos, Millicent Atujuna, Lauren Fynn, Matinatsa Mugore, Selly Mabandla, Sybil Hosek, Connie Celum, Linda-Gail Bekker, Joseph Daniel...> ;Journal of Behavioral Medicine. 2024 Apr 1
Risk of antimicrobial resistance with doxy-PEP is real, as is the need for its well-Informed implementation.
Jean-Michel Molina, Jeffrey D Klausner, Aniruddha Hazra, Connie Celum, Anne F Luetkemeyer> ;Clinical Infectious Diseases. 2024 Mar 19
HIV-1 Incidence, Adherence, and Drug Resistance in Individuals Taking Daily Emtricitabine/Tenofovir Disoproxil Fumarate for HIV-1 Pre-Exposure Prophylaxis: Pooled Anal...
Raphael J Landovitz, Li Tao, Juan Yang, Melanie de Boer, Christoph Carter, Moupali Das, Jared M Baeten, Albert Liu, Karen W Hoover, Connie Celum, Beatriz Grinsztejn, S...> ;Clinical Infectious Diseases. 2024 Mar 14
1 citations
HIV Preexposure Prophylaxis With Emtricitabine and Tenofovir Disoproxil Fumarate Among Cisgender Women.
Jeanne Marrazzo, Li Tao, Marissa Becker, Ashley A Leech, Allan W Taylor, Faith Ussery, Michael Kiragu, Sushena Reza-Paul, Janet Myers, Linda-Gail Bekker, Juan Yang, Ch...> ;JAMA. 2024 Mar 19
Filling in the Gaps: Updates on Doxycycline Prophylaxis for Bacterial Sexually Transmitted Infections.
Pyra, M., Gutierrez, J., Pickett, J., Stewart, J., Bolan, R., Molina, J., Klausner, J., Hazra, A., McNulty, M., Pagkas-Bather, J., Celum, C., Luetkemeyer, A.> ;Clinical Infectious Diseases. 2024 Feb 9
People living with HIV's perspectives of acceptability of fee for home delivery of ART: a qualitative study.
Ntinga, X., Musiello, F., Pita, T., Mabaso, N., Szpiro, A., van Rooyen, H., van Heerden, A., Celum, C., Barnabas, R.> ;BMC Health Services Research. 2024 Jan 17
"": A Multimethod Study Exploring Acceptability of Point-of-Care Viral Load Testing among Ugandan Pregnant and Postpartum Women Living with HIV.
Nakyanzi, A., Naddunga, F., Bulterys, M., Mujugira, A., Wyatt, M., Kamusiime, B., Nalumansi, A., Kasiita, V., Peacock, S., Ware, N., Celum, C.> ;Diagnostics. 2023 Dec 28
Ethical Considerations in Implementing Doxycycline Postexposure Prophylaxis for the Prevention of Bacterial Sexually Transmitted Infections.
Sugarman, J., Taylor, H., Bachmann, L., Cahill, S., Barbee, L., Celum, C., Cohen, S., Faden, R., Luetkemeyer, A., Mayer, K., Mermin, J., Upshur, R., Aral, S., Mena, L.> ;Sexually Transmitted Diseases. 2024 Mar 1
Doxycycline postexposure prophylaxis for prevention of sexually transmitted infections.
Cannon, C., Celum, C.> ;Topics in Antiviral Medicine. 2023 Dec 5
Durability of single-dose HPV vaccination in young Kenyan women: randomized controlled trial 3-year results.
Barnabas, R., Brown, E., Onono, M., Bukusi, E., Njoroge, B., Winer, R., Galloway, D., Pinder, L., Donnell, D., N Wakhungu, I., Biwott, C., Kimanthi, S., Heller, K., Ka...> ;Nature Medicine. 2023 Dec 1
7 citations
Adherence, safety, and choice of the monthly dapivirine vaginal ring or oral emtricitabine plus tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis among Af...
Gonasagrie Nair, Connie Celum, Daniel Szydlo, Elizabeth R Brown, Carolyne A Akello, Rita Nakalega, Pippa Macdonald, Gakiema Milan, Thesla Palanee-Phillips, Krishnaveni...> ;The Lancet. HIV. 2023 Dec 1
3 citations
Efficacy estimates of oral pre-exposure prophylaxis for HIV prevention in cisgender women with partial adherence.
Mia Moore, Sarah Stansfield, Deborah J Donnell, Marie-Claude Boily, Kate M Mitchell, Peter L Anderson, Sinead Delany-Moretlwe, Linda-Gail Bekker, Nyaradzo M Mgodi, Con...> ;Nature Medicine. 2023 Nov 1
The Effect of Disclosure of PrEP Use on Adherence Among African Young Women in an Open-Label PrEP Study: Findings from HPTN 082.
Geetha Beauchamp, Sybil Hosek, Deborah Donnell, Kwun C G Chan, Peter L Anderson, Bonnie J Dye, Nyaradzo Mgodi, Linda-Gail Bekker, Sinead Delany-Moretlwe, Connie Celum> ;AIDS and Behavior. 2023 Sep 28
Factors that influence adolescent girls and young women's re-initiation or complete discontinuation from daily oral PrEP use: a qualitative study from Eastern Cape Pro...
Lindsey de Vos, Emily Krogstad Mudzingwa, Lauren Fynn, Millicent Atujuna, Matinatsa Mugore, Monica Gandhi, Connie Celum, Sybil Hosek, Linda-Gail Bekker, Joseph Daniels...> ;Journal of the International AIDS Society. 2023 Sep 1
Partner testing with HIV self-test distribution by Ugandan pregnant women living with HIV: a randomized trial.
Andrew Mujugira, Agnes Nakyanzi, Deborah Donnell, Jade Boyer, Gabrielle Stein, Michelle Bulterys, Faith Naddunga, Juliet Kyomugisha, Juliet E Birungi, Paul Ssendiwala,...> ;Journal of the International AIDS Society. 2023 Sep 1
3 citations
A decision support tool has similar high PrEP uptake and increases early PrEP persistence in adolescent girls and young women in South Africa: results from a randomize...
Connie Celum, Dominika Seidman, Danielle Travill, Christine Dehlendorf, Sanele Gumede, Kidist Zewdie, Whitney Wilson, Jennifer F Morton, Jared M Baeten, Deborah Donnel...> ;Journal of the International AIDS Society. 2023 Aug 1
Understanding the barriers and facilitators of COVID-19 risk mitigation strategy adoption and COVID-19 vaccination in refugee settlements in Uganda: a qualitative study.
Robin E Klabbers, Timothy R Muwonge, Scovia Ajidiru, Sukanya Borthakur, Andrew Mujugira, Monisha Sharma, Patrick Vinck, Phuong Pham, Connie Celum, Rosalind Parkes-Rata...> ;BMC Public Health. 2023 Jul 20
3 citations
Preparing for long-acting PrEP delivery: building on lessons from oral PrEP.
Connie Celum, Beatriz Grinsztejn, Kenneth Ngure> ;Journal of the International AIDS Society. 2023 Jul 1
Implementation of HIV prevention strategies globally.
Pragna Patel, Connie Celum, Linda G Bekker> ;The Lancet. HIV. 2023 Aug 1
Feasibility and acceptability of peer-delivered HIV self-testing and PrEP for young women in Kampala, Uganda.
Rita Nakalega, Nelson Mukiza, Robert Menge, Samuel Kizito, Juliet Allen Babirye, Cynthia Ndikuno Kuteesa, Denis Mawanda, Emmie Mulumba, Josephine Nabukeera, Joseph Ggi...> ;BMC Public Health. 2023 Jun 16
1 citations
Trust in the provider and accurate self-reported PrEP adherence among adolescent girls and young women in South Africa and Zimbabwe: HPTN 082 study.
Geetha Beauchamp, Deborah Donnell, Sybil Hosek, Peter L Anderson, Kwun C G Chan, Bonnie J Dye, Nyaradzo Mgodi, Linda-Gail Bekker, Sinead Delany-Moretlwe, Connie Celum> ;BMC Women's Health. 2023 May 19
5 citations
Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling.
Alicia R Berard, Douglas K Brubaker, Kenzie Birse, Alana Lamont, Romel D Mackelprang, Laura Noël-Romas, Michelle Perner, Xuanlin Hou, Elizabeth Irungu, Nelly Mugo, Sam...> ;Cell Reports. 2023 May 30
2 citations
Upregulation of IFN-stimulated genes persists beyond the transitory broad immunologic changes of acute HIV-1 infection.
Romel D Mackelprang, Abdelali Filali-Mouhim, Brian Richardson, Francois Lefebvre, Elly Katabira, Allan Ronald, Glenda Gray, Kristen W Cohen, Nichole R Klatt, Tiffany P...> ;Iscience. 2023 Apr 21
1 citations
High prevalence and incidence of gonorrhoea and chlamydia in young women eligible for HIV pre-exposure prophylaxis in South Africa and Zimbabwe: results from the HPTN ...
Sinead Delany-Moretlwe, Nyaradzo Mgodi, Linda-Gail Bekker, Jared M Baeten, Chuwen Li, Deborah Donnell, Yaw Agyei, Denni Lennon, Scott M Rose, Marcia Mokgatle, Sheetal ...> ;Sexually Transmitted Infections. 2023 Nov 1
2 citations
'If there is joy… I think it can work well': a qualitative study investigating relationship factors impacting HIV self-testing acceptability among pregnant women and m...
Brienna Naughton, Michelle A Bulterys, Jackson Mugisha, Andrew Mujugira, Jade Boyer, Connie Celum, Bryan Weiner, Monisha Sharma> ;BMJ Open. 2023 Feb 17
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Journal Articles

Covid-19, Ebola, and HIV — Leveraging Lessons to Maximize Impact
Connie Celum, Myron S Cohen, Wafaa El-Sadr, The New England Journal of Medicine
Quadrivalent HPV Vaccine in HIV-1-Infected Early Adolescent Girls and Boys in Kenya: Month 7 and 12 Post Vaccine Immunogenicity and Correlation with Immune Status
Linda Eckert, Connie Celum, Jared M Baeten, ScienceDirect
Patterns of Oral PrEP Adherence and HIV Risk Among Eastern African Women in HIV Serodiscordant Partnerships
Elizabeth R Brown, Jessica E Haberer, Connie Celum, Jared M Baeten, AIDS and Behavior

Press Mentions

Widely Available Antibiotic Helps Prevent Bacterial STIs in Certain Populations, UW Clinical Trial FindsJune 6th, 2022
Young Women and Pregnant Women Can Effectively Use Vaginal Rings and Oral PrEP for HIV PreventionJuly 28th, 2021
UW/Fred Hutch CFAR Announces New Director and Co-DirectorApril 23rd, 2021
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Grant Support

Interventions To Decrease HIV Infectiousness In UgandaNational Institute Of Allergy And Infectious Diseases2010–2012
Multi-Component, Targeted HIV Prevention For Sub-Saharan Africa: PreventionrxNational Institute Of Allergy And Infectious Diseases2009–2012
Clinical ResearchNational Institute Of Allergy And Infectious Diseases2008–2011
Acyclovir To Prevent HIV Acquisition In Hsv-2+ PersonsNational Institute Of Allergy And Infectious Diseases2005–2007
STDS And Heterosexual 'Bridging'Among Men WHO Have SexNational Institute Of Allergy And Infectious Diseases2001–2006
Core-Clinical ResearchNational Institute Of Allergy And Infectious Diseases2004
Acylovir To Prevent HIV Acquisition In Hsv-2+PersonsNational Institute Of Allergy And Infectious Diseases2002–2004
STDS And Heterosexual Bridging Among Men WHO Have SexNational Institute Of Allergy And Infectious Diseases2000