ConnorAndrewEmdinMD

PubMed

• Author Correction: Clonal haematopoiesis and risk of chronic liver disease.
  Waihay J Wong, Connor Emdin, Alexander G Bick, Seyedeh M Zekavat, Abhishek Niroula, James P Pirruccello, Laura Dichtel, Gabriel Griffin, Md Mesbah Uddin, Christopher J...> ;Nature. 2023 Jul 1
• 35 citations
  Clonal haematopoiesis and risk of chronic liver disease.
  Waihay J Wong, Connor Emdin, Alexander G Bick, Seyedeh M Zekavat, Abhishek Niroula, James P Pirruccello, Laura Dichtel, Gabriel Griffin, Md Mesbah Uddin, Christopher J...> ;Nature. 2023 Apr 1
• 3 citations
  Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease.
  Amit V Khera, Minxian Wang, Mark Chaffin, Connor A Emdin, Nilesh J Samani, Heribert Schunkert, Hugh Watkins, Ruth McPherson, Jeanette Erdmann, Roberto Elosua, Eric Boe...> ;Circulation. Genomic and Precision Medicine. 2022 Dec 1
• 107 citations
  Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease.
  Kiran J Biddinger, Connor A Emdin, Mary E Haas, Minxian Wang, George Hindy, Patrick T Ellinor, Sekar Kathiresan, Amit V Khera, Krishna G Aragam> ;JAMA Network Open. 2022 Mar 1
• 34 citations
  Machine learning enables new insights into genetic contributions to liver fat accumulation.
  Mary E Haas, James P Pirruccello, Samuel N Friedman, Minxian Wang, Connor A Emdin, Veeral H Ajmera, Tracey G Simon, Julian R Homburger, Xiuqing Guo, Matthew Budoff, Ka...> ;Cell Genomics. 2021 Dec 8
• 48 citations
  Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease.
  Nooshin Ghodsian, Erik Abner, Connor A. Emdin, Émilie Gobeil, Nele Taba, Mary E. Haas, Nicolas Perrot, Hasanga D. Manikpurage, Éloi Gagnon, Jérôme Bourgault, Alexis St...> ;Cell Reports. Medicine. 2021 Nov 3
• 15 citations
  Selection of 51 predictors from 13,782 candidate multimodal features using machine learning improves coronary artery disease prediction
  Saaket Agrawal, Marcus D. R. Klarqvist, Connor A. Emdin, Aniruddh P. Patel, Patrick T. Ellinor, Anthony A. Philippakis, Kenney Ng, Puneet Batra, Amit Khera, Manish Par...> ;Patterns. 2021 Oct 4
• 58 citations
  Association of Genetic Variation With Cirrhosis: A Multi-Trait Genome-Wide Association and Gene-Environment Interaction Study
  Connor A. Emdin, Mary E. Haas, Veeral Ajmera, Tracey G. Simon, Julian R. Homburger, Cynthia L. Neben, Lan Jiang, Wei-Qi Wei, QiPing Feng, Alicia Y. Zhou, Joshua C. Den...> ;Gastroenterology. 2021 Apr 1
• 66 citations
  rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,...> ;Journal of Hepatology. 2021 Jan 1
• 70 citations
  Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
  Erik L. Bao, Satish K. Nandakumar, Xiaotian Liao, Alexander G. Bick, Juha Karjalainen, Marcin Tabaka, Olga I. Gan, Aki S. Havulinna, Tuomo Kiiskinen, Caleb A. Lareau, ...> ;Nature. 2020 Oct 14
• 27 citations
  Heterozygous ABCG5 Gene Deficiency and Risk of Coronary Artery Disease.
  Akihiro Nomura, Connor A. Emdin, Hong-Hee Won, Gina M. Peloso, Pradeep Natarajan, Diego Ardissino, John Danesh, Heribert Schunkert, Adolfo Correa, Matthew J. Bown, Nil...> ;Circulation. Genomic and Precision Medicine. 2020 Aug 30
• 65 citations
  A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.
  Connor A Emdin, Mary E Haas, Amit V Khera, Krishna Aragam, Mark Chaffin, Derek Klarin, George Hindy, Lan Jiang, Wei-Qi Wei, Qiping Feng, Juha Karjalainen, Aki Havulinn...> ;Plos Genetics. 2020 Apr 1
• 7 citations
  Genome-Wide Polygenic Score and Cardiovascular Outcomes With Evacetrapib in Patients With High-Risk Vascular Disease: A Nested Case-Control Study
  Connor A. Emdin, Pallav Bhatnagar, Minxian Wang, Sreekumar G. Pillai, Lin Li, Hui Rong Qian, Jeffrey S. Riesmeyer, A. Michael Lincoff, Stephen J. Nicholls, Steven E. N...> ;Circulation. Genomic and Precision Medicine. 2020 Jan 3
• 7 citations
  Epicardial and subcutaneous adipose tissue in Indigenous and non-Indigenous individuals: Implications for cardiometabolic diseases.
  David F. Sun, Nadarajah Kangaharan, Benedict T. Costello, Stephen J. Nicholls, Connor A. Emdin, Rexson Tse, Celine Gallagher, Amrina Kaur, Kurt C. Roberts-Thomson, Raj...> ;Obesity Research & Clinical Practice. 2020 Jan 1
• 28 citations
  Genetic Association of Finger Photoplethysmography-Derived Arterial Stiffness Index With Blood Pressure and Coronary Artery Disease.
  Seyedeh M. Zekavat, Krishna G. Aragam, Connor A. Emdin, Amit Khera, Derek Klarin, Hongyu Zhao, Pradeep Natarajan> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2019 Jun 1
• 18 citations
  DNA Sequence Variation in ACVR1C Encoding the Activin-Receptor Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes.
  Connor A. Emdin, Amit Khera, Krishna G. Aragam, Mary E. Haas, Mark Chaffin, Derek Klarin, Pradeep Natarajan, Alexander G. Bick, Seyedeh M. Zekavat, Akihiro Nomura, Die...> ;Diabetes. 2019 Jan 1
• 71 citations
  Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure
  Mary E. Haas, Krishna G. Aragam, Connor A. Emdin, Alexander G. Bick, Gibran Hemani, George Davey Smith, Sekar Kathiresan> ;American Journal of Human Genetics. 2018 Oct 4
• 374 citations
  Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
  Derek Klarin, Scott M. Damrauer, Kelly Cho, Yan V. Sun, Tanya M. Teslovich, Jacqueline Honerlaw, David R. Gagnon, Scott L. DuVall, Jin Li, Gina M. Peloso, Mark Chaffin...> ;Nature Genetics. 2018 Oct 1
• 83 citations
  Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
  Viktoria Gusarova, Colm O'Dushlaine, Tanya M. Teslovich, Peter N. Benotti, Tooraj Mirshahi, Omri Gottesman, Cristopher V. Van Hout, Michael F. Murray, Anubha Mahajan, ...> ;Nature Communications. 2018 Jun 13
• 72 citations
  Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum
  Andrea Ganna, F. Kyle Satterstrom, Seyedeh M. Zekavat, Indraniel Das, Mitja I. Kurki, Claire Churchhouse, Jessica Alföldi, Alicia R. Martin, Aki S. Havulinna, Andrea B...> ;American Journal of Human Genetics. 2018 Jun 7
• 48 citations
  Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease
  Connor A. Emdin, Amit Khera, Mark Chaffin, Derek Klarin, Pradeep Natarajan, Krishna G. Aragam, Mary E. Haas, Alexander G. Bick, Seyedeh M. Zekavat, Akihiro Nomura, Die...> ;Nature Communications. 2018 Apr 24
• 803 citations
  Mendelian Randomization.
  Connor A Emdin, Amit V Khera, Sekar Kathiresan> ;JAMA. 2017 Nov 21
• 378 citations
  Exome-wide association study of plasma lipids in > 300,000 individuals
  Dajiang J. Liu, Gina M. Peloso, Haojie Yu, Adam S. Butterworth, Xiao Wang, Anubha Mahajan, Danish Saleheen, Connor A. Emdin, Dewan S. Alam, Alexessander Couto Alves, P...> ;Nature Genetics. 2017 Oct 30
• 19 citations
  Genetic Variation at the Sulfonylurea Receptor, Type 2 Diabetes, and Coronary Heart Disease
  Connor A. Emdin, Derek Klarin, Pradeep Natarajan, Jose C. Florez, Sekar Kathiresan, Amit Khera> ;Diabetes. 2017 Aug 1
• 277 citations
  A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression
  Rajat M. Gupta, Joseph E. Hadaya, Aditi Trehan, Seyedeh M. Zekavat, Carolina Roselli, Derek Klarin, Connor A. Emdin, Catharina R.E. Hilvering, Valerio Bianchi, Christi...> ;Cell. 2017 Jul 27
• Join now to see all