Corrine(Lenahan)ZarwanMD

Oncology • Burlington, MA

Assistant Professor, Medicine, Tufts Medical Center

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Office
41 Mall Rd
Lahey Clinic
Burlington, MA 01805
Phone+1 781-744-8400

Fax+1 781-744-5245
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Education & Training

Beth Israel Deaconess Medical CenterFellowship, Hematology and Medical Oncology, 2003 - 2005
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 2000 - 2003
University of Florida College of MedicineClass of 2000

Certifications & Licensure

MA State Medical License 2002 - 2025

Clinical Trials

Radiation Therapy With or Without Cisplatin in Treating Patients With Recurrent Endometrial Cancer Start of enrollment: 2008 Feb 25
Active, not recruiting
Phase 2
S0812 High Dose Cholecalciferol in Premenopausal Women at High-Risk for Breast Cancer Start of enrollment: 2011 Nov 01
Completed
Not Applicable
A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer Start of enrollment: 2010 Aug 13
Completed
Phase 3
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer Start of enrollment: 2011 Jan 15
Active, not recruiting
Phase 3
Efficacy and Safety Study of NeuVax™ (Nelipepimut-S or E75) Vaccine to Prevent Breast Cancer Recurrence Start of enrollment: 2011 Nov 01
Completed
Phase 3
PRospective Study Of MammaPrint in Patients With an Intermediate Recurrence Score Start of enrollment: 2012 May 01
Completed
A Phase II Study of Everolimus in Combination With Exemestane Versus Everolimus Alone Versus Capecitabine in Advance Breast Cancer. Start of enrollment: 2013 Feb 26
Completed
Phase 2
Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer Start of enrollment: 2014 May 01
Completed
Phase 2
Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer Start of enrollment: 2017 Jan 18
Active, not recruiting
Phase 3
Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer Start of enrollment: 2019 May 14
Active, not recruiting
Making Informed Choices on Incorporating Chemoprevention Into Care (MiCHOICE) Start of enrollment: 2020 Oct 23
Recruiting
Not Applicable
Roles: Principal Investigator
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Publications & Presentations

PubMed

A randomized phase II trial of bevacizumab vs. bevacizumab and erlotinib as first-line consolidation after carboplatin, paclitaxel, and bevacizumab in newly diagnosed ...
Susana Campos, Ursula Matulonis, Suzanne Berlin, Neil Horowitz, Joyce Liu, Carolyn Krasner, Lee Hang, Corrine Zarwan, William Barry, Tina Colella, Christen Whalen, Mel...> ;International Journal of Clinical Oncology. 2022 Dec 1
34 citations
Appropriate Systemic Therapy Dosing for Obese Adult Patients With Cancer: ASCO Guideline Update
Jennifer J. Griggs, Kari Bohlke, Edward P. Balaban, James J. Dignam, Evan T. Hall, R. Donald Harvey, Diane P. Hecht, Kelsey Klute, Vicki A. Morrison, T. May Pini, Gary...> ;Journal of Clinical Oncology. 2021 May 3
1 citations
Longitudinal study of breast cancer risk markers.
Corrine Zarwan, Olivia Diamond, Prudence Lam, Musie Ghebremichael, Margaret M. Lotz, Abra H. Shen, Sheida Sharifi, Flora Rozhansky, Teresa Ann Gore, Susan E. Pories> ;The Breast Journal. 2021 Jan 1
19 citations
Outcomes of COVID-19 in Patients With a History of Cancer and Comorbid Cardiovascular Disease.
, , , , , , , , , , , , , , , , , , , , , , , , , > ;Journal of the National Comprehensive Cancer Network. 2020 Nov 3
12 citations
Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D Supplementation in Premenopausal Women at High Risk for Breast Cancer (SWOG S0812)
Katherine D. Crew, Garnet L. Anderson, Dawn L. Hershman, Mary Beth Terry, Parisa Tehranifar, Danika L. Lew, Monica Yee, Eric Brown, Sebastien S. Kairouz, Nafisa Kuwaje...> ;Cancer Prevention Research. 2019 Jul 1
242 citations
Open-label Clinical Trial of Niraparib Combined With Pembrolizumab for Treatment of Advanced or Metastatic Triple-Negative Breast Cancer.
Shaveta Vinayak, Sara M. Tolaney, Lee S. Schwartzberg, Monica M. Mita, Georgia A. McCann, Antoinette R. Tan, Andrea E. Wahner-Hendrickson, Andres Forero, Carey K. Ande...> ;JAMA Oncology. 2019 Jun 13
40 citations
Upfront dexrazoxane for the reduction of anthracycline-induced cardiotoxicity in adults with preexisting cardiomyopathy and cancer: a consecutive case series
Sarju Ganatra, Anju Nohria, Sachin P. Shah, John D. Groarke, Ajay K. Sharma, David M. Venesy, Richard D. Patten, Krishna S Gunturu, Corrine Zarwan, Tomas G. Neilan, An...> ;Cardio-Oncology. 2019 Jan 29
102 citations
Avelumab in patients with previously treated metastatic adrenocortical carcinoma: phase 1b results from the JAVELIN solid tumor trial
Christophe Le Tourneau, Christopher J. Hoimes, Corrine Zarwan, Deborah J. Wong, Sebastian Bauer, Rainer Claus, Martin Wermke, Subramanian Hariharan, Anja von Heydebrec...> ;Journal for Immunotherapy of Cancer. 2018 Oct 22
6 citations
Early-Onset 5-Fluorouracil Toxicity in a Patient Negative for Dihydropyrimidine Dehydrogenase Mutations: The Clinical Course of Reversal with Uridine Triacetate.
Christine E. Vaudo, Brigitte Gil, Kari Galuski, Corrine Zarwan, Francis W. Nugent> ;Pharmacotherapy. 2016 Nov 1
49 citations
Selective Blockade of Matrix Metalloprotease-14 with a Monoclonal Antibody Abrogates Invasion, Angiogenesis, and Tumor Growth in Ovarian Cancer
Rajani Kaimal, Raid Aljumaily, Sarah L. Tressel, Rutika V. Pradhan, Lidija Covic, Athan Kuliopulos, Corrine Zarwan, Young B. Kim, Sheida Sharifi, Anika Agarwal> ;Cancer Research. 2013 Apr 15
8 citations
Induction of antitumor immunity ex vivo using dendritic cells transduced with fowl pox vector expressing MUC1, CEA, and a triad of costimulatory molecules (rF-PANVAC).
Baldev Vasir, Corrine Zarwan, Rehan Ahmad, Keith D. Crawford, Hassan Rajabi, Ken-ichi Matsuoka, Jacalyn Rosenblatt, Zekui Wu, Heidi Mills, Donald Kufe, David Avigan> ;Journal of Immunotherapy. 2012 Sep 1
Eribulin mesylate (halichondrin B analog E7389) in platinum-sensitive ovarian cancer: A phase II study, CTEP #7431.
Hensley ML, Kravetz SJ, Jia X, Tew WP, Pereira L, Sabbatini P, Whalen C, Aghajanian C, Zarwan C, Berlin ST> ;J. Clin. Oncol.. 2011-05-20
23 citations
Generation of tumor-specific T lymphocytes using dendritic cell/tumor fusions and anti-CD3/CD28.
Jacalyn Rosenblatt, Zekui Wu, Baldev Vasir, Corrine Zarwan, Richard Stone, Heidi Mills, Thea M. Friedman, Panagiotis A. Konstantinopoulos, Dimitrios Spentzos, Musie Gh...> ;Journal of Immunotherapy. 2010 Feb 1
31 citations
Immunomodulatory effects of vitamin D: implications for GVHD
Jacalyn Rosenblatt, Adam Bissonnette, Rehan Ahmad, Zekui Wu, Baldev Vasir, Kristen E. Stevenson, Corrine Zarwan, Whitney Keefe, Brett Glotzbecker, Heidi Mills, Robin J...> ;Bone Marrow Transplantation. 2010 Jan 18
217 citations
Cediranib, an Oral Inhibitor of Vascular Endothelial Growth Factor Receptor Kinases, Is an Active Drug in Recurrent Epithelial Ovarian, Fallopian Tube, and Peritoneal ...
Ursula A. Matulonis, Suzanne Berlin, Percy Ivy, Karin Tyburski, Carolyn N. Krasner, Corrine Zarwan, Anna Berkenblit, Susana M. Campos, Neil S. Horowitz, Stephen A. Can...> ;Journal of Clinical Oncology. 2009 Nov 20
Eribulin mesylate (halichondrin B Analog E7389) in platinum-resistant epithelial ovarian cancer (PR-EOC): A CTEP-sponsored phase II study.
Hensley ML, Kravetz S, Sima C, Tew W, Pereira L, Sabbatini P, Whalen C, Aghajanian CA, Zarwan C, Berlin S> ;J. Clin. Oncol.. 2009-05-20
37 citations
Fusions of Dendritic Cells with Breast Carcinoma Stimulate the Expansion of Regulatory T Cells while Concomitant Exposure to IL-12, CpG Oligodeoxynucleotides, and Anti...
Baldev Vasir, Zekui Wu, Keith D. Crawford, Jacalyn Rosenblatt, Corrine Zarwan, Adam Bissonnette, Donald Kufe, David Avigan> ;Journal of Immunology. 2008 Jul 1
17 citations
Dendritic cell defects in patients with cancer: mechanisms and significance.
Corrine Lenahan, David Avigan> ;Breast Cancer Research. 2006 Jan 5
The role of tumor markers in breast cancer management.
Corrine Lenahan, Lilit Garibyan, Susan E. Pories> ;Current Surgery. 2004 Nov 1
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Press Mentions

Clinical Trials 101: What You Need to KnowJanuary 8th, 2019
Cancer Survivor Teresa Gately Touts Clinical Trials and Positive Attitude in Fighting DiseaseAugust 23rd, 2018