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Costas Hadjipanayis, MD, Neurosurgery, Pittsburgh, PA, Mount Sinai West

CostasHadjipanayisMDPhD

Neurosurgery • Pittsburgh, PA

Brain & Spinal Tumor, Stereotactic & Functional Neurosurgery

L. Dade Lunsford Professor of Neurosurgery, Executive Vice-Chairman, Dept. of Neurological Surgery, Director, Center For Image-Guided Neurosurgery, Co-Director, UPMC Hillman Brain Tumor Center Director, Brain Tumor Nanotechnology Laboratory, Hillman Cancer Center, University of Pittsburgh Medical Center (UPMC), University of Pittsburgh School of Medicine

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Summary

  • Dr. Hadjipanayis is a board-certified neurosurgeon who has devoted his entire career to the treatment of brain tumor patients. He completed his neurosurgical residency and graduate Ph.D. training at the University of Pittsburgh School of Medicine with additional neurosurgical oncology training at the University of California San Francisco. He is the inaugural L. Dade Lunsford Professor of Neurological Surgery at UPMC and will serve as Executive Vice-Chairman for the Dept. of Neurological Surgery. Dr. Hadjipanayis has taken over as Director of the UPMC Center for Image-Guided Neurosurgery from his mentor Dr. L. Dade Lunsford. He will also serve as Co-Director of the newly formed UPMC Brain Tumor Center at the Hillman Cancer Center. Dr. Hadjipanayis directs the Brain Tumor Nanotechnology Laboratory in the Hillman Cancer Center and has been the principal investigator of multiple clinical trials and university-, private foundation-, and NIH-funded grants focused on brain tumors. He was recently recruited back from the Icahn School of Medicine at Mount Sinai in New York City where he served as the Chairman of Neurosurgery at Mount Sinai Union Square/Beth Israel and the Director of Neurosurgical Oncology for the Mount Sinai Health System. Dr. Hadjipanayis has focused much of his career on innovation, translational research, and intraoperative technology development. In 2011, Dr. Hadjipanayis was the first to use 5-ALA (Gleolan) and perform fluorescence-guided surgery (FGS) in the US and helped lead the FDA approval of Gleolan for glioma surgery in June 2017. He has also led the development of a voice-controlled robotic-assisted exoscope for neurosurgery. He is an elected member of the American Academy of Neurological Surgeons and the Society of Neurological Surgeons (SNS). Dr. Hadjipanayis has been a tireless brain tumor advocate serving on the nonprofit boards of the Southeastern Brain Tumor Foundation (SBTF) and StacheStrong.

Education & Training

  • UPMC Medical Education
    UPMC Medical EducationResidency, Neurological Surgery, 1999 - 2006
  • University of Pittsburgh School of Medicine
    University of Pittsburgh School of MedicinePost-Doctoral Fellowship, Molecular Genetics and Bioche, 2003 - 2005
  • University of Pittsburgh School of Medicine
    University of Pittsburgh School of MedicinePh.D., Biochemistry/Molecular Genetics, 2005
  • UPMC Medical Education (Pittsburgh)
    UPMC Medical Education (Pittsburgh)Residency, Surgery, 1998 - 1999
  • Sidney Kimmel Medical College at Thomas Jefferson University
    Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1998
  • University of Delaware
    University of DelawareBA, Major: Medical Scholar's Program, Minor: Medical Humanities, Magna Cum Laude, 1990 - 1994

Certifications & Licensure

  • FL State Medical License
    FL State Medical License 2020 - Present
  • NY State Medical License
    NY State Medical License 2015 - 2024
  • PA State Medical License
    PA State Medical License 2022 - 2024
  • PA State Medical License
    PA State Medical License 1999 - 2024
  • GA State Medical License
    GA State Medical License 2007 - 2016
  • American Board of Neurological Surgery Neurological Surgery

Awards, Honors, & Recognition

  • Best Poster, Nanomedicine Translational Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, 2015
  • Reviewer Excellence Award Neurosurgery, 2015
  • Fellow Robert Woodruff Leadership Academy, 2014
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Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Targeted Therapy of Glioma Stem-like Cells and Tumor Non-stem Cells Using Cetuximab Conjugated Iron Oxide Nanoparticles  
    Kaluzova M, Bouras A, Machaidze R, Hadjipanayis CG, Oncotarget, 1/20/2015
  • Radiosensitivity Enhancement of Radioresistant Glioblastoma by Epidermal Growth Factor Receptor Antibody-conjugated Iron-oxide Nanoparticles  
    Bouras A, Kaluzova M, Hadjipanayis CG, J Neurooncol, 1/1/2015
  • Human Brat Ortholog TRIM3 Is a Tumor Suppressor and Regulates Asymmetric Cell Division in Glioblastoma  
    Chen G, Anand M, Kong J, Tucker-Burden C, Rong Y, Rahman F, Moreno CS, Van Meir EG, Hadjipanayis CG, Brat DJ, Cancer Res, 1/15/2014
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Books/Book Chapters

  • Karl Storz Educational Book Series 
    Chapter: Neuroendoscopic Colloid Cyst Resection 
    Editors: Costas G. Hadjipanayis.2014
  • Fudamentals of Basic Science and Clinical Medicine 
    Chapter: CNS Tumors: Primary and Metastatic. Neurology Section 
    Reinertsen E and Hadjipanayis CG1st2013
  • General Principles of Neurosurgery 
    Chapter: Pineal Gland Tumors: Epidemiology, Etiology, Diagnosis, and Treatment. 
    Bouras A and Hadjipanayis CGEditors: Fountas K.2013
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Abstracts/Posters

  • Targeted Therapy of Glioma Stem Cells and Tumor Non-stem Cells Using Cetuximab-conjugated Iron-oxide Nanoparticles
    Kaluzova M, Platt S, Bouras A, Kent M, Machaidze R, Hadjipanayis CG, Fourth Quadrennial Meeting of the World Federation of Neuro-oncology, San Francisco, CA, 1/24/2013
  • Endoscopic Endonasal Resection of Clival Chordomas
    Ormond RD, Wise S, Oyesiku N, Patel A, Hadjipanayis CG, 23rd Annual North American Skull Base Society Meeting, Journal of Neurological Surgery-Part B Skull Base, Miami, FL, 1/1/2013
  • Targeted Therapy of Glioma Stem Cells and Tumor Non-stem Cells Using Cetuximab-conjugated Iron-oxide Nanoparticles
    Kaluzova M, Platt S, Bouras A, Kent M, Machaidze R, Hadjipanayis CG, Neurooncology, 1/1/2013
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Lectures

  • Skull Base Endoscopic Surgery: Instrumentation and Techniques 
    Madurai Neurosurgical Academy, Chennai, India - 1/28/2015
  • Endoscopic Endonasal Approach to Pituitary Tumors 
    Madurai Neurosurgical Academy, Chennai, India - 1/28/2015
  • Endoscopic Endonasal Resection of Clival Chordoma 
    Madurai Neurosurgical Academy, Chennai, India - 1/28/2015
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Other

Press Mentions

  • Synaptive Medical Présente Des Fonctionnalités Clefs De Sa Technologie De Microscopie Chirurgicale Robotique Modus V™ Lors Du CNS 2019
    Synaptive Medical Présente Des Fonctionnalités Clefs De Sa Technologie De Microscopie Chirurgicale Robotique Modus V™ Lors Du CNS 2019October 15th, 2019
  • Synaptive Medical Presents Key Features of Its Modus V™ Robotic Surgical Microscopy Technology at the 2019 CNS Annual Meeting
    Synaptive Medical Presents Key Features of Its Modus V™ Robotic Surgical Microscopy Technology at the 2019 CNS Annual MeetingOctober 15th, 2019
  • FDA Approves Gliolan; Helps Patients with Glioblastoma Brain Tumors
    FDA Approves Gliolan; Helps Patients with Glioblastoma Brain TumorsJuly 27th, 2017
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Professional Memberships

Hospital Affiliations

Dr. Costas Hadjipanayis, Dr. Costas Hadjipanayis, MD, Dr. C Hadjipanayis