CraigBrianWilenMD

PubMed

• 36 citations
  A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice
  Tianyang Mao, Benjamin Israelow, Carolina Lucas, Chantal B.F. Vogels, Maria Luisa Gomez-Calvo, Olga Fedorova, Mallery I. Breban, Bridget L. Menasche, Huiping Dong, Mel...> ;The Journal of Experimental Medicine. 2022 Jan 3
• 3 citations
  LRRC15 is an inhibitory receptor blocking SARS-CoV-2 spike-mediated entry in trans
  Jaewon Song, Ryan D. Chow, Mario A Peña-Hernández, Li Zhang, Skylar A Loeb, Eui Young So, Olin D Liang, Craig B. Wilen, Sanghyun Lee> ;Biorxiv. 2021 Nov 24
• 39 citations
  De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: A case report
  Shiv Gandhi, Jonathan Klein, Alexander Robertson, Mario A Peña-Hernández, Michelle J. Lin, Pavitra Roychoudhury, Peiwen Lu, John Fournier, David Ferguson, Shah A Moham...> ;Medrxiv. 2021 Nov 9
• 8 citations
  Distinct Roles of Type I and Type III Interferons During a Native Murine β Coronavirus Lung Infection.
  Lokesh Sharma, Xiaohua Peng, Hua Qing, Brandon K. Hilliard, Joo-Young Kim, Anush Swaminathan, Justin Tian, Kavita Israni-Winger, Cuiling Zhang, Victoria Habet, Lin Wan...> ;Journal of Virology. 2021 Oct 27
• 244 citations
  Viral replication in human macrophages enhances an inflammatory cascade and interferon driven chronic COVID-19 in humanized mice.
  Esen Sefik, Rihao Qu, Eleanna Kaffe, Jun Zhao, Haris Mirza, Ricky Brewer, Ailin Han, Holly R. Steach, Benjamin Israelow, Y. Grace Chen, Stephanie Halene, Akiko Iwasaki...> ;Biorxiv. 2021 Sep 27
• 100 citations
  Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy.
  Irfan Ullah, Jérémie Prévost, Mark S. Ladinsky, Helen Stone, Maolin Lu, Sai Priya Anand, Guillaume Beaudoin-Bussières, Kelly Symmes, Mehdi Benlarbi, Shilei Ding, Romai...> ;Immunity. 2021 Sep 14
• 65 citations
  Restriction of SARS-CoV-2 replication by targeting programmed -1 ribosomal frameshifting.
  Yu Sun, Laura Abriola, Rachel O. Niederer, Savannah F. Pedersen, Mia Madel Alfajaro, Valter Vinicius Silva Monteiro, Craig B. Wilen, Ya Chi Ho, Wendy V. Gilbert, Yulia...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Jun 29
• 6 citations
  A stem-loop RNA RIG-I agonist confers prophylactic and therapeutic protection against acute and chronic SARS-CoV-2 infection in mice
  Tianyang Mao, Benjamin Israelow, Carolina Lucas, Chantal B.F. Vogels, Olga Fedorova, Mallery I. Breban, Bridget L. Menasche, Huiping Dong, Melissa M. Linehan, Yale SAR...> ;Biorxiv. 2021 Jun 17
• 115 citations
  Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein.
  Jack C.-C. Hsu, Maudry Laurent-Rolle, Joanna B. Pawlak, Craig B. Wilen, Peter Cresswell> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Jun 15
• Author Correction: Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes.
  Ya-Ting Wang, Konstantin Zaitsev, Qun Lu, Shan Li, W. Timothy Schaiff, Ki-Wook Kim, Lindsay Droit, Craig B. Wilen, Chandni Desai, Dale R. Balce, Robert C. Orchard, Ant...> ;Nature Microbiology. 2021 May 25
• 23 citations
  Plasmodium infection induces cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein
  Sarah Lapidus, Feimei Liu, Arnau Casanovas-Massana, Yile Dai, John D. Huck, Carolina Lucas, Jon Klein, Renata B. Filler, Madison S. Strine, Mouhamad Sy, Awa B. Deme, A...> ;Medrxiv. 2021 May 12
• 47 citations
  Stability of SARS-CoV-2 RNA in Nonsupplemented Saliva.
  , , , , , , , , , , , , , , , , , , , , , , > ;Emerging Infectious Diseases. 2021 Apr 1
• 60 citations
  Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy
  Irfan Ullah, Jérémie Prévost, Mark S. Ladinsky, Helen Stone, Maolin Lu, Sai Priya Anand, Guillaume Beaudoin-Bussières, Kelly Symmes, Mehdi Benlarbi, Shilei Ding, Romai...> ;Biorxiv. 2021 Mar 22
• 137 citations
  Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes.
  Neal G. Ravindra, Mia Madel Alfajaro, Victor Gasque, Nicholas C. Huston, Han Wan, Klara Szigeti-Buck, Yuki Yasumoto, Allison M. Greaney, Victoria Habet, Ryan D. Chow, ...> ;Plos Biology. 2021 Mar 17
• 14 citations
  A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options
  Esen Sefik, Ben Israelow, Jun Zhao, Rihao Qu, Eric Song, Haris Mirza, Eleanna Kaffe, Stephanie Halene, Eric Meffre, Yuval Kluger, Michel C. Nussenzweig, Craig B. Wilen...> ;Research Square. 2021 Mar 17
• 106 citations
  Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.
  Ryan A. Flynn, Julia A. Belk, Yanyan Qi, Yuki Yasumoto, Jin Wei, Mia Madel Alfajaro, Quanming Shi, Maxwell R. Mumbach, Aditi Limaye, Peter C DeWeirdt, Cameron O. Schmi...> ;Cell. 2021 Apr 29
• 11 citations
  Norovirus evolution in immunodeficient mice reveals potentiated pathogenicity via a single nucleotide change in the viral capsid.
  Forrest C. Walker, Ebrahim Hassan, Stefan T. Peterson, Rachel Rodgers, Lawrence A. Schriefer, Cassandra E Thompson, Yuhao Li, Gowri Kalugotla, Carla Blum-Johnston, Dyl...> ;Plos Pathogens. 2021 Mar 11
• 57 citations
  Non-steroidal anti-inflammatory drugs dampen the cytokine and antibody response to SARS-CoV-2 infection.
  Jennifer S. Chen, Mia Madel Alfajaro, Ryan D. Chow, Jin Wei, Renata B. Filler, Stephanie C. Eisenbarth, Craig B. Wilen> ;Journal of Virology. 2021 Jan 13
• 20 citations
  UFMylation inhibits the proinflammatory capacity of interferon-γ-activated macrophages.
  Dale R. Balce, Ya-Ting Wang, Michael R. McAllaster, Bria F. Dunlap, Anthony Orvedahl, Barry L. Hykes, Lindsay Droit, Scott A. Handley, Craig B. Wilen, John G. Doench, ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Jan 5
• 155 citations
  Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms.
  Nicholas C. Huston, Han Wan, Madison S. Strine, Rafael de Cesaris Araujo Tavares, Craig B. Wilen, Anna Marie Pyle> ;Molecular Cell. 2021 Feb 4
• 58 citations
  An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2.
  Takuya Tada, Jennifer S. Chen, Ramanjit Kaur, Kenneth A. Stapleford, Harry B. Gristick, Belinda M Dcosta, Craig B. Wilen, Crina M. Nimigean, Nathaniel R. Landau> ;Cell Reports. 2020 Dec 22
• 7 citations
  Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase and Solute Carrier Family 35 Member A1 Are Required for Reovirus Binding and Infection.
  Kelly Urbanek, Danica M. Sutherland, Robert C. Orchard, Craig B. Wilen, Jonathan J. Knowlton, Pavithra Aravamudhan, Gwen M. Taylor, Herbert W. Virgin, Terence S. Dermody> ;Journal of Virology. 2020 Dec 22
• 253 citations
  Mouse Model of SARS-CoV-2 Reveals Inflammatory Role of Type I Interferon Signaling
  Benjamin Israelow, Eric Song, Tianyang Mao, Peiwen Lu, Amit Meir, Feimei Liu, Mia Madel Alfajaro, Jin Wei, Huiping Dong, Robert J. Homer, Aaron M. Ring, Craig B. Wilen...> ;The Journal of Experimental Medicine. 2020 Dec 7
• 133 citations
  Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity.
  Jonathan R. Brestoff, Craig B. Wilen, John R. Moley, Yongjia Li, Wei Zou, Nicole P. Malvin, Marina N. Rowen, Brian Saunders, Hongming Ma, Madison R. Mack, Barry L. Hyk...> ;Cell Metabolism. 2021 Feb 2
• 14 citations
  CD300lf Conditional Knockout Mouse Reveals Strain-Specific Cellular Tropism of Murine Norovirus.
  Vincent R. Graziano, Mia Madel Alfajaro, Cameron O. Schmitz, Renata B. Filler, Madison S. Strine, Jin Wei, Leon L. Hsieh, Megan T. Baldridge, Timothy J. Nice, Sanghyun...> ;Journal of Virology. 2021 Jan 13
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