CristinaGaleArriensMDMSCS

Rheumatology • Oklahoma City, OK

Lupus & Related

Clinical Associate Professor

Join to view full profile

Dr. Arriens is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Arriens' full profile

Already have an account?

Office
825 Northeast 13th Street
Oklahoma City, OK 73104
Phone+1 405-271-7805

Fax+1 405-271-8797
Is this information wrong?

Education & Training

University of Texas Southwestern Medical SchoolMS, Clinical Science, 2013 - 2015
University of Texas Southwestern Medical CenterFellowship, Rheumatology, 2011 - 2013
University of New Mexico School of MedicineResidency, Internal Medicine, 2007 - 2010
University of Texas Southwestern Medical SchoolClass of 2007

Certifications & Licensure

OK State Medical License 2015 - 2024
TX State Medical License 2011 - 2024
NM State Medical License 2007 - 2016
American Board of Internal Medicine Rheumatology

Awards, Honors, & Recognition

John M Thomas, MD Scholarship Southwestern Medical Foundation, 2003
Member Golden Key National Honor Society, 2002
University Honors Texas A&M Honors Program, 2002
Member Phi Kappa Phi, 2002
University Undergraduate Research Fellow Texas A&M Honors Program, 2002
Texas A&M University President's Endowed Scholarship Texas A&M University Honors Program, 1999-2002
Join now to see all

Clinical Trials

Pilot Study - Effect of Omega-3 on Systemic Lupus Erythematosus Start of enrollment: 2012 Jan 01
Completed
Phase 2
Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis Start of enrollment: 2014 Mar 14
Completed
Phase 4
Clarification of Abatacept Effects in SLE With Integrated Biologic and Clinical Approaches Start of enrollment: 2014 Jan 01
Completed
Phase 2
Evaluation of Belimumab Impact on a BLyS Activity Signature Test in the Absence of Confounding Polypharmacy Start of enrollment: 2014 Oct 01
Unknown status
Phase 4
Efficacy and Safety of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus Start of enrollment: 2015 Jun 09
Completed
Phase 3
Safety and Efficacy of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Proliferative Lupus Nephritis Start of enrollment: 2015 Nov 04
Completed
Phase 2
Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis Start of enrollment: 2016 Apr 27
Terminated
Phase 2
Long Term Safety of Anifrolumab in Adult Subjects With Active Systemic Lupus Erythematosus Start of enrollment: 2016 Jun 30
Completed
Phase 3
Methotrexate Withdrawal Study of Tofacitinib Modified Release Formulation in Subjects With Rheumatoid Arthritis Start of enrollment: 2016 Sep 01
Completed
Phase 4
Aurinia Renal Response in Active Lupus With Voclosporin Start of enrollment: 2017 May 17
Completed
Phase 3
Study of Anti-Malarials in Incomplete Lupus Erythematosus Start of enrollment: 2017 Dec 28
Active, not recruiting
Phase 2
An Investigational Study to Evaluate BMS-986165 in Participants With Systemic Lupus Erythematosus Start of enrollment: 2017 Sep 21
Completed
Phase 2
MRI Evaluation Assessing Synovitis to Address the Unmet Need for Reliable Endpoints in SLE Start of enrollment: 2017 Apr 10
Terminated
Phase 2
Aurinia Renal Assessments 2: Aurinia Renal Response in Lupus With Voclosporin Start of enrollment: 2019 Sep 29
Completed
Phase 3
A Study of Baricitinib in Participants With Systemic Lupus Erythematosus (SLE-BRAVE II) Start of enrollment: 2018 Aug 02
Completed
Phase 3
A Study of Baricitinib in Participants With Systemic Lupus Erythematosus (SLE) Start of enrollment: 2019 Sep 09
Terminated
Phase 3
A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis Start of enrollment: 2019 Apr 25
Active, not recruiting
Phase 4
Long-Term Safety and Efficacy Study of Deucravacitinib in Participants With Systemic Lupus Erythematosus Start of enrollment: 2019 Mar 26
Active, not recruiting
Phase 2
An Investigational Study to Evaluate the Safety and Effectiveness of BMS-986165 With Background Treatment in Participants With Lupus Nephritis Start of enrollment: 2019 Jul 15
Terminated
Phase 2
Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate Start of enrollment: 2019 May 16
Completed
Phase 3
Efficacy and Safety of GSK3196165 (Otilimab) Versus Placebo and Sarilumab in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Biological Disease-modifying Antirheumatic Drug (DMARDs) and/or Janus Kinase (JAK) Inhibitors Start of enrollment: 2019 Oct 31
Completed
Phase 3
A Study of LY3471851 in Adults With Systemic Lupus Erythematosus (SLE) Start of enrollment: 2020 Aug 19
Completed
Phase 2
Join now to see all

Publications & Presentations

PubMed

Neutrophils isolated from systemic lupus erythematosus patients exhibit a distinct functional phenotype.
Neelakshi R Jog, Catriona A Wagner, Teresa Aberle, Joel M Guthridge, Judith A James, Eliza F Chakravarty, Cristina Arriens> ;Frontiers in Immunology. 2024 Jan 1
Ancestry-based differences in the immune phenotype are associated with lupus activity.
Samantha Slight-Webb, Kevin Thomas, Miles Smith, Catriona A Wagner, Susan Macwana, Aleksandra Bylinska, Michele Donato, Mai Dvorak, Sarah E Chang, Alex Kuo, Peggie Che...> ;JCI Insight. 2023 Aug 22
11 citations
Safety and Efficacy of Long-Term Voclosporin Treatment for Lupus Nephritis in the Phase 3 AURORA 2 Clinical Trial.
Amit Saxena, Ellen M Ginzler, Keisha Gibson, Bancha Satirapoj, Adolfina Elizabeth Zuta Santillán, Olena Levchenko, Sandra Navarra, Tatsuya Atsumi, Shinsuke Yasuda, Nil...> ;Arthritis & Rheumatology. 2024 Jan 1
1 citations
Protocol for virtual physical examination in an observational, longitudinal study evaluating virtual outcome measures in SLE.
Anca D Askanase, Cynthia Aranow, Mimi Y Kim, Diane L Kamen, Cristina Arriens, Leila Khalili, Julia Barasch, Maria Dall'Era, Meggan Mackay, Tang, W., Wei Tang> ;Lupus Science & Medicine. 2023 Jul 1
1 citations
A Flare Risk Index Informed by Select Immune Mediators in Systemic Lupus Erythematosus.
Melissa E Munroe, Derek Blankenship, Daniele DeFreese, Mohan Purushothaman, Wade DeJager, Susan Macwana, Joel M Guthridge, Stan Kamp, Nancy Redinger, Teresa Aberle, El...> ;Arthritis & Rheumatology. 2023 May 1
8 citations
Update on the Efficacy and Safety Profile of Voclosporin: An Integrated Analysis of Clinical Trials in Lupus Nephritis.
Cristina Arriens, Y K Onno Teng, Ellen M Ginzler, Samir V Parikh, Anca D Askanase, Amit Saxena, Keisha Gibson, Dawn J Caster, Tatsuya Atsumi, Laura Lisk, Simrat Randha...> ;Arthritis Care & Research. 2023 Jul 1
170 citations
Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial.
Brad H. Rovin, Y K Onno Teng, Ellen M. Ginzler, Cristina Arriens, Dawn J. Caster, Juanita Romero-Diaz, Keisha L. Gibson, Joshua Kaplan, Laura Lisk, Sandra V. Navarra, ...> ;Lancet. 2021 May 29
15 citations
Immune Response to Enterococcus gallinarum in Lupus Patients Is Associated With a Subset of Lupus-Associated Autoantibodies.
Harini Bagavant, Antonina M Araszkiewicz, Jessica K Ingram, Katarzyna Cizio, Joan T. Merrill, Cristina Arriens, Joel M. Guthridge, Judith A. James, Umesh S. Deshmukh> ;Frontiers in Immunology. 2021 May 28
5 citations
A Multianalyte Assay Panel With Cell-Bound Complement Activation Products Predicts Transition of Probable Lupus to American College of Rheumatology-Classified Lupus.
Rosalind Ramsey-Goldman, Roberta Vezza Alexander, John Conklin, Cristina Arriens, Sonali Narain, Elena Massarotti, Daniel J. Wallace, Christopher E Collins, Amit Saxen...> ;ACR Open Rheumatology. 2021 Feb 4
12 citations
Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with s...
Rebecca A. Wood, Lauren Guthridge, Emma Thurmond, Carla J. Guthridge, Joseph M Kheir, Rebecka L. Bourn, Catriona A. Wagner, Hua Chen, Wade DeJager, Susan R. Macwana, S...> ;Journal of Translational Autoimmunity. 2021 Jan 1
1 citations
Creatinine Fluctuation in Patients With Lupus Nephritis: Considerations for Clinical Trial Endpoints
Salem Almaani, Udayan Bhatt, Cristina Arriens, Eloisa Bonfa, Maria Dall'Era, Frédéric Houssiau, Kenneth C. Kalunian, Megan Mackay, Jorge Sanchez-Guerrero, Neil Solomon...> ;Kidney International Reports. 2020 May 23
22 citations
Autoantibody-positive healthy individuals with lower lupus risk display a unique immune endotype
Samantha Slight-Webb, Miles Smith, Aleksandra Bylinska, Susan R. Macwana, Carla J. Guthridge, Joan T. Merrill, Eliza F. Chakravarty, Cristina Arriens, Melissa E. Munro...> ;The Journal of Allergy and Clinical Immunology. 2020 Dec 1
6 citations
Cell-bound complement activation products associate with lupus severity in SLE.
Cristina Arriens, Roberta Vezza Alexander, Sonali Narain, Amit Saxena, Christopher E Collins, Daniel J. Wallace, Elena Massarotti, John Conklin, Kenneth C. Kalunian, C...> ;Lupus Science & Medicine. 2020 Apr 1
36 citations
Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study.
Joel M. Guthridge, Rufei Lu, Ly Thi-Hai Tran, Cristina Arriens, Teresa Aberle, Stan Kamp, Melissa E. Munroe, Nicolas Dominguez, Timothy Gross, Wade DeJager, Susan R. M...> ;Eclinicalmedicine. 2020 Mar 4
12 citations
Lupus patient decisions about clinical trial participation: a qualitative evaluation of perceptions, facilitators and barriers
Cristina Arriens, Teresa Aberle, Fredonna Carthen, Stan Kamp, Aikaterini Thanou, Eliza F. Chakravarty, Judith A. James, Joan T. Merrill, Motolani E. Ogunsanya> ;Lupus Science & Medicine. 2020 Mar 1
30 citations
Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic...
Rosalind Ramsey-Goldman, Roberta Vezza Alexander, Elena Massarotti, Daniel J. Wallace, Sonali Narain, Cristina Arriens, Christopher E Collins, Amit Saxena, Chaim Putte...> ;Arthritis & Rheumatology. 2020 Jan 1
17 citations
Scoring Systemic Lupus Erythematosus (SLE) Disease Activity With Simple, Rapid Outcome Measures
Aikaterini Thanou, Judith A. James, Cristina Arriens, Teresa Aberle, Eliza F. Chakravarty, Joseph Rawdon, Stavros Stavrakis, Joan T. Merrill, Anca Askanase> ;Lupus Science & Medicine. 2019 Dec 30
1 citations
Mock Recruitment for the Study of Antimalarials in an Incomplete Lupus Erythematosus Trial.
David R. Karp, Benjamin F. Chong, Judith A. James, Cristina Arriens, Mariko L. Ishimori, Daniel J. Wallace, Duanping Liao, Nancy J. Olsen> ;Arthritis Care & Research. 2019 Nov 1
35 citations
Establishing Surrogate Kidney End Points for Lupus Nephritis Clinical Trials: Development and Validation of a Novel Approach to Predict Future Kidney Outcomes.
Meggan Mackay, Maria Dall'Era, Joanna Fishbein, Kenneth C. Kalunian, Martin Lesser, Jorge Sanchez-Guerrero, Deborah M. Levy, Earl D. Silverman, Michelle Petri, Cristin...> ;Arthritis & Rheumatology. 2019 Mar 1
22 citations
Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE): study protocol for a randomized controlled trial
Nancy J. Olsen, Judith A. James, Cristina Arriens, Mariko L. Ishimori, Daniel J. Wallace, Diane L. Kamen, Benjamin F. Chong, Duanping Liao, Vernon M. Chinchilli, David...> ;Trials. 2018 Dec 20
16 citations
Prognostic significance of repeat biopsy in lupus nephritis: Histopathologic worsening and a short time between biopsies is associated with significantly increased ris...
Cristina Arriens, Sixia Chen, David R. Karp, Ramesh Saxena, Kamalanathan K. Sambandam, Eliza F. Chakravarty, Judith A. James, Joan T. Merrill> ;Clinical Immunology. 2017 Dec 1
48 citations
Systemic lupus erythematosus biomarkers: the challenging quest
Cristina Arriens, Jonathan D. Wren, Melissa E. Munroe, Chandra Mohan> ;Rheumatology. 2016 Dec 24
60 citations
Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE
Jacob J. Orme, Yong Du, Kamala Vanarsa, Jessica M. Mayeux, Li Li, Azza Mutwally, Cristina Arriens, So Youn Min, Jack Hutcheson, Laurie S. Davis, Benjamin F. Chong, Ann...> ;Clinical Immunology. 2016 Aug 1
45 citations
Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study.
Tianfu Wu, Huihua Ding, Jie Han, Cristina Arriens, Chungwen Wei, Weilu Han, Claudia Pedroza, Shan Jiang, Jennifer H. Anolik, Michelle Petri, Ignacio Sanz, Ramesh Saxen...> ;Journal of Proteome Research. 2016 Jun 7
15 citations
Nonalcoholic fatty liver disease: a potential consequence of tumor necrosis factor-inhibitor therapy.
Linda A. Feagins, Avegail Flores, Cristina Arriens, Christina Park, Terri W. Crook, Andreas M. Reimold, Geri Brown> ;European Journal of Gastroenterology & Hepatology. 2015 Sep 18
Join now to see all

Journal Articles

Mock Recruitment for the Study of Antimalarials in Incomplete Lupus Erythematosus Trial
Benjamin F Chong, Cristina Arriens, David R Karp, Judith A James, Arthritis Care & Research

Press Mentions

Aurinia Pharmaceuticals Announces Presentations at American College of Rheumatology (ACR) Convergence 2022September 20th, 2022
ACR Leads AMA Resolution on Payer Financial Incentives to Patients to Switch TreatmentMay 22nd, 2021
Successful Resolutions, Policy Updates at AMA House of Delegates 2020 Interim MeetingJanuary 24th, 2021
Join now to see all

Grant Support

T32NIH NIDDK2013–2015

Committees

Delegate for The American College of Rheumatology, American Medical Association - Young Physicians Section 2015 - Present
Member, Lupus Nephritis Trials Network

Research History

Undergraduate Research StudentTexas A&M University - Biochemistry & Biophysics University Undergraduate Research Thesis: C Arriens. Comparative Studies of Diverged Members of the Phosphotriesterase Family, 2002 Fellows Thesis A762, available at Evans Library at Texas A&M University.1999 - 2002