
Crystal S Denlinger MD
Gastrointestinal Cancer, Hematologic Oncology
Senior Vice President, Chief Scientific Officer, National Comprehensive Cancer Network
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3025 Chemical RdSuite 100Plymouth Meeting, PA 19462
Phone+1 267-622-6654
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Summary
- Provides oversight to NCCN’s Oncology Research Program and select Compendia products. Participates in NCCN policy and global initiatives. Practicing clinician with part-time voluntary faculty appointment at Fox Chase Cancer Center.
Education & Training
- Temple University Hospital-Fox Chase Cancer CenterFellowship, Hematology and Medical Oncology, 2004 - 2007
- Icahn School of Medicine at Mount Sinai/Mount Sinai HospitalResidency, Internal Medicine, 2001 - 2004
- Rutgers New Jersey Medical SchoolClass of 2001
Certifications & Licensure
- PA State Medical License 2004 - 2026
- NY State Medical License 2002 - 2004
- American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
- Fellow American College of Physicians
Clinical Trials
- Phase I Safety Study of the Drug MM-121 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment Start of enrollment: 2008 Jul 01
- Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery Start of enrollment: 2009 Oct 28
- Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer Start of enrollment: 2011 Apr 27
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Publications & Presentations
PubMed
- NCCN Policy Summit: Advancing Diversity, Equity, and Inclusion in the Cancer Workforce.Ashley Orr, Taneal Carter, Alyssa A Schatz, Eugene Manley Jr, Rodney Tucker
Journal of the National Comprehensive Cancer Network. 2025-07-30 - 2 citationsMeasuring and Addressing Health-Related Social Needs in Cancer.Victoria Hood, Alyssa Schatz, Yelak Biru, Loretta Erhunmwunsee, Crystal S Denlinger
Journal of the National Comprehensive Cancer Network. 2025-07-15 - 1 citationsZanidatamab plus chemotherapy as first-line treatment for patients with HER2-positive advanced gastro-oesophageal adenocarcinoma: primary results of a multicentre, sin...Elena Elimova, Jaffer Ajani, Howard Burris, Crystal S Denlinger, Syma Iqbal
The Lancet. Oncology. 2025-07-01
Journal Articles
- KRASG12C Inhibition with Sotorasib in Advanced Solid TumorsDavid S Hong, Marwan G Fakih, Gregory A Durm, Geoffrey I Shapiro, Gerald S Falchook, Adrian Sacher, Crystal S Denlinger, John C Krauss, Andrew L Coveler, Suresh S Rama..., The New England Journal of Medicine
Authored Content
- Cardiovascular Toxicity in Cancer Survivors: Current Guidelines and Future DirectionsJune 2018
Press Mentions
- Best Practices for Managing Primary Care of Patients After Cancer TreatmentAugust 20th, 2025
- National Comprehensive Cancer Network Launches NCCN Guidelines NavigatorJuly 1st, 2025
- Trusted Oncology Guidelines Get a Digital Makeover: National Comprehensive Cancer Network Launches NCCN Guidelines NavigatorJune 24th, 2025
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Grant Support
- NCCN Foundation Young Investigator AwardNCCN Foundation2012–2014
Committees
- Chair, NCCN Survivorship Guidelines Panel 2012 - Present
- Member, Chemotherapy subcommittee, NCCN Esophagogastric Cancers Guidelines Panel 2009 - Present
- Member, NCI Esophagogastric Task Force 2012 - 2013
Professional Memberships
- Member
- Member
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