D. WadeClappMD
Neonat/Perinatology • Indianapolis, INRichard L. Schreiner Professor and Chair, Department of Pediatrics, Indiana University School of Medicine
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Office
705 Riley Hospital Dr
RI 5900
Indianapolis, IN 46202Phone+1 317-944-7810Fax+1 317-944-4471- Is this information wrong?
Summary
- I am the Chairman of Pediatrics and the Physician-in-Chief at Riley Hospital for Children. I am interested in leading the coordination of patient friendly children's health, in developing pediatricians (both general and subspecialty trained) and in innovation in children's health broadly. Our Department is consistently in the top 10 Departments in the US in NIH funding, we have broad fellowship and physician-scientist training programs and with the support of the Riley Children's Foundation, IU School of Medicine and in partnership with IU Health Hospitals, we are able to conduct broad based basic, translational, and clinical research that is leading to innovations in multiple areas and first in man therapies. I am also a physician-scientist who is interested in genetic diseases with a predisposition to cancer in infants and young children. My laboratory is particularly focused on malignant and non-malignant manifestations of neurofibromatosis type 1
Education & Training
Case Western Reserve University/University Hospitals Cleveland Medical CenterFellowship, Research, 1989 - 1990- Case Western Reserve Univ/Univ Hosps Cleveland Med Ctr/Rainbow Babies and Childrens HospitalFellowship, Neonatal-Perinatal Medicine, 1986 - 1989
Indiana University School of MedicineInternship, Pediatrics, 1982 - 1985- Indiana University School of MedicineClass of 1982
Certifications & Licensure
IN State Medical License 1983 - 2025
OH State Medical License 1986 - 1992- American Board of Pediatrics Pediatrics
- American Board of Pediatrics Neonatalogy
Awards, Honors, & Recognition
- Fellow American Association for Advancement of Science, 2022
- Membership National Academy of Medicine, 2020
- Elected Member The American Society for Clinical Investigation, 2001
Publications & Presentations
PubMed
- Correction: Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours.Silpa Gampala, Fenil Shah, Chi Zhang, Steven D Rhodes, Olivia Babb, Michelle Grimard, Randall S Wireman, Ellie Rad, Brian Calver, Ren-Yuan Bai, Verena Staedtke, Emily ...> ;British Journal of Cancer. 2022 Oct 1
- 3 citationsMitotic Errors Promote Genomic Instability and Leukemia in a Novel Mouse Model of Fanconi Anemia.Donna Edwards, Dana Mitchell, Zahi Abdul-Sater, Ka-Kui Chan, Zejin Sun, Aditya Sheth, Ying He, Li Jiang, Jin Yuan, Richa Sharma, Magdalena Czader, Pei-Ju Chin, Yie Liu...> ;Frontiers in Oncology. 2021 Nov 5
- 14 citationsBrigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK.Long-Sheng Chang, Janet L. Oblinger, Abbi Smith, Marc Ferrer, Steven P. Angus, Eric T. Hawley, Alejandra M. Petrilli, Roberta L. Beauchamp, Lars Björn Riecken, Serkan ...> ;Plos One. 2021 Jul 15
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Grant Support
- Developmental Hyperactive Ras Tumor SPORENational Cancer Institute2021–2026
- F-box Ubiquitin ligases destabilize neurofibrominNINDS2018–2023
- Targeted Therapeutics for NF2 in a Pre-Clinical ModelDepartment of Defense2018–2021
Professional Memberships
- Member
- Member
- Member
- Member
Hospital Affiliations
Riley Hospital for Children at IU HealthIndianapolis, Indiana
External Links
- D. Wade Clapphttp://www.neonatology.iupui.edu/faculty/d-wade-clapp
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