DaiLuMD

PubMed

• 25 citations
  Translational potential of allosteric modulators targeting the cannabinoid CB 1 receptor
  Dai Lu, Sri Sujana Immadi, Zhixing Wu, Debra A. Kendall> ;Acta Pharmacologica Sinica. 2019 Mar 1
• 10 citations
  Pyrimidinyl Biphenylureas Act as Allosteric Modulators to Activate Cannabinoid Receptor 1 and Initiate β-Arrestin-Dependent Responses.
  Caitlin A. D. Jagla, Caitlin E. Scott, Yaliang Tang, Chang-jiang Qiao, Gabriel E. Mateo-Semidey, Guillermo A. Yudowski, Dai Lu, Debra A. Kendall> ;Molecular Pharmacology. 2019 Jan 1
• 7 citations
  Exploring 6-Azaindole and 7-Azaindole Rings for Developing Cannabinoid Receptor 1 Allosteric Modulators.
  Sri Sujana Immadi, Rachel Dopart, Zhixing Wu, Boqiao Fu, Debra A. Kendall, Dai Lu> ;Cannabis and Cannabinoid Research. 2018 Dec 8
• 25 citations
  Recent advances in the discovery of small-molecule inhibitors of HIV-1 integrase.
  Eungi Choi, Jayapal Reddy Mallareddy, Dai Lu, Srikanth Kolluru> ;Future Science OA. 2018 Sep 6
• 25 citations
  Allosteric modulators of cannabinoid receptor 1: developing compounds for improved specificity.
  Rachel Dopart, Dai Lu, Aron H. Lichtman, Debra A. Kendall> ;Drug Metabolism Reviews. 2018 Jan 21
• 27 citations
  Controlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes.
  Dai Lu, Rachel Dopart, Debra A. Kendall> ;Cell Stress & Chaperones. 2016 Jan 1
• 51 citations
  Class IIa HDAC inhibition enhances ER stress-mediated cell death in multiple myeloma.
  Shohei Kikuchi, Rikio Suzuki, Hiroto Ohguchi, Yasuhiro Yoshida, D Lu, Francesca Cottini, Jana Jakubikova, Giada Bianchi, Takeshi Harada, Gullu Gorgun, Yu-Tzu Tai, Paul...> ;Leukemia. 2015 Mar 24
• 2 citations
  (4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)(cyclohexyl)methanone hydrochloride (LDK1229): a new cannabinoid CB1 receptor inverse agonist from the class of benzhydryl...
  Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu, Debra A. Kendall> ;Molecular Pharmacology. 2015 Feb 1
• CSNK1α1 mediates malignant plasma cell survival.
  Hu, Y.,Song, W.,Cirstea, D.,Lu, D.,Munshi, N. C.,Anderson, K. C.> ;Leukemia. 2014 Jun 26
• 34 citations
  Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1).
  Leepakshi Khurana, Hamed I. Ali, Teresa Olszewska, Kwang H. Ahn, Aparna Damaraju, Debra A. Kendall, Dai Lu> ;Journal of Medicinal Chemistry. 2014 Apr 10
• 25 citations
  SN-38-Cyclodextrin Complexation and Its Influence on the Solubility, Stability, and In Vitro Anticancer Activity Against Ovarian Cancer
  Kiran Kumar Vangara, Hamed I. Ali, Dai Lu, Jingbo Louise Liu, Srikanth Kolluru, Srinath Palakurthi> ;AAPS Pharmscitech. 2014 Jan 30
• 28 citations
  Profiling two indole-2-carboxamides for allosteric modulation of the CB1 receptor.
  Kwang H. Ahn, Mariam M. Mahmoud, Sushma Samala, Dai Lu, Debra A. Kendall> ;Journal of Neurochemistry. 2013 Mar 1
• 5 citations
  Magnetically Aligned Bicelles To Study the Orientation of Lipophilic Ligands in Membrane Bilayers
  Jianxin Guo, De-Ping Yang, Ravi Chari, Xiaoyu Tian, Spiro Pavlopoulos, Dai Lu, Alexandros Makriyannis> ;Journal of Medicinal Chemistry. 2008 Oct 4
• 15 citations
  Bornyl- and isobornyl-Delta8-tetrahydrocannabinols: a novel class of cannabinergic ligands.
  Dai Lu, Jianxian Guo, Richard I. Duclos, Anna L. Bowman, Alexandros Makriyannis> ;Journal of Medicinal Chemistry. 2008 Oct 23
• Enhancement of intracellular delivery of CdTe quantum dots (QDs) to living cells by Tat conjugation.
  Xue FL, Chen JY, Guo J, Wang CC, Yang WL, Wang PN, Lu DR> ;J Fluoresc. 2007-03-01
• Cell-based selection of internalizing fully human antagonistic antibodies directed against FLT3 for suppression of leukemia cell growth.
  Williams B, Atkins A, Zhang H, Lu D, Jimenez X, Li H, Wang M, Ludwig D, Balderes P, Witte L, Li Y, Zhu Z> ;Leukemia. 2005-08-01
• Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affi...
  Zhu Z, Hattori K, Zhang H, Jimenez X, Ludwig DL, Dias S, Kussie P, Koo H, Kim HJ, Lu D, Liu M, Tejada R, Friedrich M, Bohlen P, Witte L, Rafii S> ;Leukemia. 2003-03-01
• Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine ...
  Lu D, Jimenez X, Zhang H, Wu Y, Bohlen P, Witte L, Zhu Z> ;Cancer Res.. 2001-10-01
• Serum TNFalpha levels in patients with acute graft-versus-host disease after bone marrow transplantation.
  Huang XJ, Wan J, Lu DP> ;Leukemia. 2001-07-01
• Identification of the residues in the extracellular region of KDR important for interaction with vascular endothelial growth factor and neutralizing anti-KDR antibodies.
  Lu D, Kussie P, Pytowski B, Persaud K, Bohlen P, Witte L, Zhu Z> ;J. Biol. Chem.. 2000-05-12
• Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody.
  Zhu Z, Lu D, Kotanides H, Santiago A, Jimenez X, Simcox T, Hicklin DJ, Bohlen P, Witte L> ;Cancer Lett.. 1999-03-01
• CBFA2, frequently rearranged in leukemia, is not responsible for a familial leukemia syndrome.
  Legare RD, Lu D, Gallagher M, Ho C, Tan X, Barker G, Shimizu K, Ohki M, Lenny N, Hiebert S, Gilliland DG> ;Leukemia. 1997-12-01
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