DanielMGreifMD

Cardiology • Guilford, CT

Adult Congenital Heart Disease

Assistant Professor, Internal Medicine, Yale University School of Medicine

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Office
111 Goose Ln
Guilford, CT 06437
Phone+1 203-458-2097
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Education & Training

Stanford Health Care-Sponsored Stanford UniversityFellowship, Cardiovascular Disease, 2003 - 2006
Brigham and Women's HospitalResidency, Internal Medicine, 1999 - 2000
University of WashingtonResidency, Internal Medicine, 1997 - 1999
University of California San Francisco School of MedicineClass of 1997

Certifications & Licensure

CA State Medical License 2003 - Present
CT State Medical License 2010 - 2025

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Publications & Presentations

PubMed

Heterogeneity of hepatocyte dynamics restores liver architecture after chemical, physical or viral damage.
Ruz-Maldonado, I., Gonzalez, J., Zhang, H., Sun, J., Bort, A., Kabir, I., Kibbey, R., Suárez, Y., Fernández-Hernando, C., Greif, D.> ;Nature Communications. 2024 Feb 10
Presenilin-1 in smooth muscle cells facilitates hypermuscularization in elastin aortopathy.
Junichi Saito, Jui M Dave, Freddy Duarte Lau, Daniel M Greif> ;Iscience. 2024 Jan 19
Dedifferentiated early postnatal lung myofibroblasts redifferentiate in adult disease.
Rachana R Chandran, Taylor S Adams, Inamul Kabir, Eunate Gallardo-Vara, Naftali Kaminski, Brigitte N Gomperts, Daniel M Greif> ;Frontiers in Cell and Developmental Biology. 2024 Jan 1
10 citations
The age of bone marrow dictates the clonality of smooth muscle-derived cells in atherosclerotic plaques.
Inamul Kabir, Xinbo Zhang, Jui M Dave, Raja Chakraborty, Rihao Qu, Rachana R Chandran, Aglaia Ntokou, Eunate Gallardo-Vara, Binod Aryal, Noemi Rotllan, Rolando Garcia-...> ;Nature Aging. 2023 Jan 1
5 citations
Vascular pathobiology of pulmonary hypertension.
Eunate Gallardo-Vara, Aglaia Ntokou, Jui M Dave, Daniel G Jovin, Fatima Z Saddouk, Daniel M Greif> ;The Journal of Heart and Lung Transplantation. 2023 May 1
19 citations
Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.
Raja Chakraborty, Allison C Ostriker, Yi Xie, Jui M Dave, Ana Gamez-Mendez, Payel Chatterjee, Yaw Abu, Jake Valentine, Kimberly Lezon-Geyda, Daniel M Greif, Vincent P ...> ;Circulation. 2022 Jun 7
17 citations
JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency.
Jui M Dave, Raja Chakraborty, Aglaia Ntokou, Junichi Saito, Fatima Z Saddouk, Zhonghui Feng, Ashish Misra, George Tellides, Robert K Riemer, Zsolt Urban, Caroline Kinn...> ;The Journal of Clinical Investigation. 2022 Mar 1
19 citations
Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis.
Rachana R Chandran, Yi Xie, Eunate Gallardo-Vara, Taylor Adams, Rolando Garcia-Milian, Inamul Kabir, Abdul Q Sheikh, Naftali Kaminski, Kathleen A Martin, Erica L Herzo...> ;Nature Communications. 2021 Dec 10
SNCs meet SMCs in the atherosclerotic plaque.
Inamul Kabir, Daniel M Greif> ;Nature Aging. 2021 Aug 1
2 citations
Mogamulizumab-Associated Acute Myocarditis in a Patient With T-Cell Lymphoma.
Jennifer M. Kwan, Natalija Odanovic, Amit Arbune, Angela Y. Higgins, Mariana L. Henry, Daniel Greif, Francine M. Foss, Lauren A. Baldassarre> ;JACC. Case Reports. 2021 Jul 7
26 citations
Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension
Aglaia Ntokou, Jui M. Dave, Amy C. Kauffman, Maor Sauler, Changwan Ryu, John Hwa, Erica L. Herzog, Inderjit Singh, W. Mark Saltzman, Daniel Greif> ;JCI Insight. 2021 Mar 22
22 citations
Macrophage-derived netrin-1 drives adrenergic nerve-associated lung fibrosis
Ruijuan Gao, Xueyan Peng, Carrighan Perry, Huanxing Sun, Aglaia Ntokou, Changwan Ryu, Jose L. Gomez, Benjamin C. Reeves, Anjali Walia, Naftali Kaminski, Nir Neumark, G...> ;The Journal of Clinical Investigation. 2021 Jan 4
52 citations
Targeting smooth muscle cell phenotypic switching in vascular disease.
Raja Chakraborty, Payel Chatterjee, Jui M. Dave, Allison C. Ostriker, Daniel Greif, Eva M. Rzucidlo, Kathleen A. Martin> ;JVS-Vascular Science. 2021 Jan 1
84 citations
Promoters to Study Vascular Smooth Muscle.
Raja Chakraborty, Fatima Zahra Saddouk, Ana Catarina Carrao, Diane S. Krause, Daniel Greif, Kathleen A. Martin> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2019 Apr 1
Implementation of a stable, high-power optical lattice for quantum gas microscopy.
Mazurenko, A.,Blatt, S.,Huber, F.,Parsons, M. F.,Chiu, C. S.,Ji, G.,Greif, D.,Greiner, M.> ;Rev Sci Instrum. 2019 Apr 01
16 citations
Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain.
Jui M Dave, Teodelinda Mirabella, Scott D Weatherbee, Daniel M Greif> ;Developmental Cell. 2018 Nov 5
1 citations
Vagal Nerve Stimulation for Pulmonary Hypertension: Some Promise, Some Skepticism.
Aglaia Ntokou, Daniel Greif> ;JACC. Basic to Translational Science. 2018 Oct 1
48 citations
NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy
Alexandre Dubrac, Steffen E. Künzel, Sandrine H. Künzel, Jinyu Li, Rachana Radhamani Chandran, Kathleen A. Martin, Daniel Greif, Ralf H. Adams, Anne Eichmann> ;Nature Communications. 2018 Aug 27
112 citations
Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells
Ashish Misra, Zhonghui Feng, Rachana Radhamani Chandran, Inamul Kabir, Noemi Rotllan, Binod Aryal, Abdul Q. Sheikh, Ling Ding, Lingfeng Qin, Carlos Fernández-Hernando,...> ;Nature Communications. 2018 May 25
54 citations
Cell Autonomous and Non-cell Autonomous Regulation of SMC Progenitors in Pulmonary Hypertension.
Abdul Q. Sheikh, Fatima Zahra Saddouk, Aglaia Ntokou, Renata Mazurek, Daniel Greif> ;Cell Reports. 2018 Apr 24
10 citations
Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain.
Jui M Dave, Teodelinda Mirabella, Scott D Weatherbee, Daniel M Greif> ;Developmental Cell. 2018 Mar 26
Using In Vivo and Tissue and Cell Explant Approaches to Study the Morphogenesis and Pathogenesis of the Embryonic and Perinatal Aorta.
Ashish Misra, Zhonghui Feng, Jiasheng Zhang, Zhi-Yin Lou, Daniel Greif> ;Journal of Visualized Experiments. 2017 Sep 12
23 citations
mTOR (Mechanistic Target of Rapamycin) Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice
Yang Jiao, Guangxin Li, Qingle Li, Rahmat Ali, Lingfeng Qin, Wei Li, Yibing Qyang, Daniel Greif, Arnar Geirsson, Jay D. Humphrey, George Tellides> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2017 Jul 27
Basic research: Where do new endothelial cells come from in the injured heart?
Daniel Greif, Anne Eichmann> ;Nature Reviews. Cardiology. 2017 Aug 3
65 citations
Vascular Cells in Blood Vessel Wall Development and Disease
R Mazurek, Jui M. Dave, Rachana Radhamani Chandran, Ashish Misra, Abdul Q. Sheikh, Daniel Greif> ;Advances in Pharmacology. 2017 Jan 1
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Press Mentions

Study Finds Aging of Bone Marrow Accelerates Arterial Plaque FormationFebruary 2nd, 2023
Breath of Hope for Pulmonary Hypertension PatientsFebruary 27th, 2014
AHA Announces 2023 Early Career Investigator Award FinalistsNovember 19th, 2023