DanielY.LohMD

PubMed

• Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development.
  Seavitt JR, White LS, Murphy KM, Loh DY, Perlmutter RM, Thomas ML> ;Mol. Cell. Biol.. 1999-06-01
• Multiple gene duplication and expression of mouse bcl-2-related genes, A1.
  Hatakeyama S, Hamasaki A, Negishi I, Loh DY, Sendo F, Nakayama K, Nakayama K> ;Int. Immunol.. 1998-05-01
• The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling.
  Cheng AM, Negishi I, Anderson SJ, Chan AC, Bolen J, Loh DY, Pawson T> ;Proc. Natl. Acad. Sci. U.S.A.. 1997-09-02
• Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell.
  Matsuzaki Y, Nakayama K, Nakayama K, Tomita T, Isoda M, Loh DY, Nakauchi H> ;Blood. 1997-02-01
• Transfected Drosophila cells as a probe for defining the minimal requirements for stimulating unprimed CD8+ T cells.
  Cai Z, Brunmark A, Jackson MR, Loh D, Peterson PA, Sprent J> ;Proc. Natl. Acad. Sci. U.S.A.. 1996-12-10
• Expansion of natural (NK1+) T cells that express alpha beta T cell receptors in transporters associated with antigen presentation-1 null and thymus leukemia antigen po...
  Joyce S, Negishi I, Boesteanu A, DeSilva AD, Sharma P, Chorney MJ, Loh DY, Van Kaer L> ;J. Exp. Med.. 1996-10-01
• Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors.
  Nakayama K, Ishida N, Shirane M, Inomata A, Inoue T, Shishido N, Horii I, Loh DY, Nakayama K> ;Cell. 1996-05-31
• Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice.
  Nagata M, Nakauchi H, Nakayama K, Nakayama K, Loh D, Watanabe T> ;Am. J. Pathol.. 1996-05-01
• Permissive recognition during positive selection.
  Pawlowski TJ, Singleton MD, Loh DY, Berg R, Staerz UD> ;Eur. J. Immunol.. 1996-04-01
• Functional significance of the Fas molecule in naive lymphocytes.
  Senju S, Negishi I, Motoyama N, Wang F, Nakayama K, Nakayama K, Lucas PJ, Hatakeyama S, Zhang Q, Yonehara S, Loh DY> ;Int. Immunol.. 1996-03-01
• T-B cell interaction inhibits spontaneous apoptosis of mature lymphocytes in Bcl-2-deficient mice.
  Nakayama K, Nakayama K, Dustin LB, Loh DY> ;J. Exp. Med.. 1995-10-01
• Essential role for ZAP-70 in both positive and negative selection of thymocytes.
  Negishi I, Motoyama N, Nakayama K, Nakayama K, Senju S, Hatakeyama S, Zhang Q, Chan AC, Loh DY> ;Nature. 1995-08-03
• V(D)J recombination and allelic exclusion of a TCR beta-chain minilocus occurs in the absence of a functional promoter.
  Alvarez JD, Anderson SJ, Loh DY> ;J. Immunol.. 1995-08-01
• Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response.
  Lucas PJ, Negishi I, Nakayama K, Fields LE, Loh DY> ;J. Immunol.. 1995-06-01
• Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia.
  Nakayama K, Nakayama K, Negishi I, Kuida K, Sawa H, Loh DY> ;Proc. Natl. Acad. Sci. U.S.A.. 1994-04-26
• Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.
  Nakayama K, Nakayama K, Negishi I, Kuida K, Louie MC, Kanagawa O, Nakauchi H, Loh DY> ;Science. 1994-02-25
• Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association.
  Chan IT, Limmer A, Louie MC, Bullock ED, Fung-Leung WP, Mak TW, Loh DY> ;Science. 1993-09-17
• Positive selection of T lymphocytes on fibroblasts.
  Pawlowski T, Elliott JD, Loh DY, Staerz UD> ;Nature. 1993-08-12
• Separation of CD4+ functional responses by peptide dose in Th1 and Th2 subsets expressing the same transgenic antigen receptor.
  Wang R, Abrams SI, Loh DY, Hsieh CS, Murphy KM, Russell JH> ;Cell. Immunol.. 1993-05-01
• Differential activation of antigen-stimulated suicide and cytokine production pathways in CD4+ T cells is regulated by the antigen-presenting cell.
  Wang R, Murphy KM, Loh DY, Weaver C, Russell JH> ;J. Immunol.. 1993-05-01
• Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.
  Shinkai Y, Koyasu S, Nakayama K, Murphy KM, Loh DY, Reinherz EL, Alt FW> ;Science. 1993-02-05
• Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer.
  Azuma T, Motoyama N, Fields LE, Loh DY> ;Int. Immunol.. 1993-02-01
• CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny.
  Fung-Leung WP, Wallace VA, Gray D, Sha WC, Pircher H, Teh HS, Loh DY, Mak TW> ;Eur. J. Immunol.. 1993-01-01
• CD45RA and CD45RBhigh expression induced by thymic selection events.
  Wallace VA, Fung-Leung WP, Timms E, Gray D, Kishihara K, Loh DY, Penninger J, Mak TW> ;J. Exp. Med.. 1992-12-01
• Cellular and peptide requirements for in vitro clonal deletion of immature thymocytes.
  Iwabuchi K, Nakayama K, McCoy RL, Wang F, Nishimura T, Habu S, Murphy KM, Loh DY> ;Proc. Natl. Acad. Sci. U.S.A.. 1992-10-01
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