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24541 Pacific Park DriveSuite 210Aliso Viejo, CA 92656
Phone+1 321-259-7111
Dr. Rossignol is on Doximity
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Education & Training
University of Virginia Medical CenterResidency, Family Medicine, 1997 - 2000
Virginia Commonwealth University School of MedicineClass of 1997
Certifications & Licensure
FL State Medical License 2006 - 2027
SC State Medical License 2000 - 2027
WI State Medical License 2006 - 2027
AZ State Medical License 2022 - 2026
CA State Medical License 2011 - 2026
VA State Medical License 1998 - 2026
American Board of Family Medicine Family Medicine
Clinical Trials
- A Controlled Trial of the Clinical Effects of Hyperbaric Therapy in Autistic Children Start of enrollment: 2006 Jun 01
- Study of Fluconazole in Children With Autism Spectrum Disorder Start of enrollment: 2009 Jul 01
Publications & Presentations
PubMed
- Early biomarker for autism spectrum disorder unveiled - what are we learning?Daniel A Rossignol, Richard E Frye
Expert Review of Molecular Diagnostics. 2025-08-01 - 36 citationsBiomarkers of mitochondrial dysfunction in autism spectrum disorder: A systematic review and meta-analysis.Richard E Frye, Patrick J McCarty, Nicole Rincon, Patrick J McCarty, Danielle Brister
Neurobiology of Disease. 2024-07-01 - 5 citationsBinding Folate Receptor Alpha Autoantibody Is a Biomarker for Leucovorin Treatment Response in Autism Spectrum Disorder.Richard E Frye, Patrick J McCarty, Patrick J McCarty, Brianna A Werner, Adrienne C Scheck
Journal of Personalized Medicine. 2024-01-01
Press Mentions
Leucovorin Label Update Targets Autism Symptoms in Cerebral Folate DeficiencySeptember 24th, 2025
Is Chelation Therapy Effective for Autism?February 28th, 2011
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