DanielSanghoonShinMDPhD

PubMed

• 1 citations
  Dysregulation of SWI/SNF Chromatin Remodelers in NSCLC: Its Influence on Cancer Therapies including Immunotherapy.
  Yijiang Shi, Daniel Sanghoon Shin> ;Biomolecules. 2023 Jun 13
• 6 citations
  EGFR pathway targeting drugs in head and neck cancer in the era of immunotherapy.
  James J Kang, Albert Ko, Sang Hoon Kil, Jon Mallen-St Clair, Daniel Sanghoon Shin, Marilene B Wang, Eri S Srivatsan> ;Biochimica Et Biophysica Acta. Reviews on Cancer. 2023 Jan 1
• 10 citations
  Shorter versus longer corticosteroid duration and recurrent immune checkpoint inhibitor-associated AKI.
  Shruti Gupta, Clara Garcia-Carro, Jason M Prosek, Ilya Glezerman, Sandra M Herrmann, Pablo Garcia, Ala Abudayyeh, Nuttha Lumlertgul, A Bilal Malik, Sebastian Loew, Paz...> ;Journal for Immunotherapy of Cancer. 2022 Sep 1
• 7 citations
  Acute kidney injury in patients receiving pembrolizumab combination therapy versus pembrolizumab monotherapy for advanced lung cancer.
  Shruti Gupta, Ian A Strohbehn, Qiyu Wang, Paul E Hanna, Rituvanthikaa Seethapathy, Jason M Prosek, Sandra M Herrmann, Ala Abudayyeh, A Bilal Malik, Sebastian Loew, Chr...> ;Kidney International. 2022 Oct 1
• 1 citations
  In Vitro Effects of Permethrin on Sinonasal Epithelia.
  Jivianne T Lee, Hong-Ho Yang, Daniel Sanghoon Shin, Eri Srivatsan, Saroj Basak> ;OTO Open. 2022 Jul 14
• 8 citations
  Targeting EZH2 to overcome the resistance to immunotherapy in lung cancer.
  Daniel Sanghoon Shin, Kevin Park, Edward Garon, Steven Dubinett> ;Seminars in Oncology. 2022 Jul 2
• 11 citations
  Key Players of the Immunosuppressive Tumor Microenvironment and Emerging Therapeutic Strategies.
  Kevin Park, Mysore S Veena, Daniel Sanghoon Shin> ;Frontiers in Cell and Developmental Biology. 2022 Jan 1
• 65 citations
  Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma
  Anusha Kalbasi, Mito Tariveranmoshabad, Kevin Hakimi, Sarah Kremer, Katie M. Campbell, Juan M. Funes, Agustin Vega-Crespo, Giulia Parisi, Ameya Champekar, Christine Ng...> ;Science Translational Medicine. 2020 Oct 14
• 145 citations
  Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression.
  Garcia-Diaz, A., Shin, D., Moreno, B., Saco, J., Escuin-Ordinas, H., Rodriguez, G., Zaretsky, J., Sun, L., Hugo, W., Wang, X., Parisi, G., Saus, C., Torrejon, D., Grae...> ;Cell Reports. 2019 Dec 10
• 544 citations
  Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression.
  Garcia-Diaz, A., Shin, D., Moreno, B., Saco, J., Escuin-Ordinas, H., Rodriguez, G., Zaretsky, J., Sun, L., Hugo, W., Wang, X., Parisi, G., Saus, C., Torrejon, D., Grae...> ;Cell Reports. 2017 May 9
• 89 citations
  Acute kidney injury in patients treated with immune checkpoint inhibitors.
  Shruti Gupta, Samuel A.P. Short, Meghan E. Sise, Jason Prosek, Sethu M. Madhavan, María José Soler, Marlies Ostermann, Sandra M. Herrmann, Ala Abudayyeh, Shuchi Anand,...> ;Journal for Immunotherapy of Cancer. 2021 Oct 1
• 4 citations
  Osimertinib as neoadjuvant therapy in a patient with stage IIIA non-small cell lung cancer: a case report
  Caroline Y. Chen, Charlene M. Fares, Daniel Sanghoon Shin> ;Journal of Medical Case Reports. 2021 Apr 24
• 51 citations
  Erratum: Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma (Cancer Cell (2020) 38(4) (500–515.e3), (S15356108...
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Cancer Cell. 2021 Jan 11
• Dysregulation of hsa-miR-34a and hsa-miR-449a leads to overexpression of PACS-1 and loss of DNA damage response (DDR) in cervical cancer.
  Veena MS, Raychaudhuri S, Basak SK, Venkatesan N, Kumar P, Biswas R, Chakrabarti R, Lu J, Su T, Gallagher-Jones M, Morselli M, Fu H, Pellegrini M, Goldstein T, Aladjem...> ;The Journal of biological chemistry. 2020-10-07
• Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma.
  Grasso CS, Tsoi J, Onyshchenko M, Abril-Rodriguez G, Ross-Macdonald P, Wind-Rotolo M, Champhekar A, Medina E, Torrejon DY, Shin DS, Tran P, Kim YJ, Puig-Saus C, Campbe...> ;Cancer cell. 2020-09-10
• 4 citations
  Leucocytosis and Stroke in a Lung Cancer Patient.
  Neha Akkad, Yang Jiang, Daniel Shin> ;European Journal of Case Reports in Internal Medicine. 2020 Aug 14
• 26 citations
  A randomized, phase 1, placebo-controlled trial of APG-157 in oral cancer demonstrates systemic absorption and an inhibitory effect on cytokines and tumor-associated m...
  , , , , , , , , , , , , , , , , , , , , , > ;Cancer. 2020 Apr 15
• Clinical Features and Outcomes of Immune Checkpoint Inhibitor-Associated AKI: A Multicenter Study.
  Cortazar FB, Kibbelaar ZA, Glezerman IG, Abudayyeh A, Mamlouk O, Motwani SS, Murakami N, Herrmann SM, Manohar S, Shirali AC, Kitchlu A, Shirazian S, Assal A, Vijayan A...> ;Journal of the American Society of Nephrology : JASN. 2020-01-02
• 15 citations
  Global alteration of T-lymphocyte metabolism by PD-L1 checkpoint involves a block of de novo nucleoside phosphate synthesis
  Nicolaos Palaskas, Jacob David Garcia, Daniel Sanghoon Shin, Cristina Puig-Saus, Daniel Braas, Antoni Ribas, Thomas G. Graeber> ;Cell Discovery. 2019 Nov 26
• 6 citations
  Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation.
  Srinivas Aluri, Rongbao Zhao, Daniel Sanghoon Shin, Andras Fiser, I. David Goldman> ;The Journal of Biological Chemistry. 2019 May 3
• Genetic Mechanisms of Immune Evasion in Colorectal Cancer.
  Grasso CS, Giannakis M, Wells DK, Hamada T, Mu XJ, Quist M, Nowak JA, Nishihara R, Qian ZR, Inamura K, Morikawa T, Nosho K, Abril-Rodriguez G, Connolly C, Escuin-Ordin...> ;Cancer discovery. 2018-03-06
• 847 citations
  Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations.
  Daniel Sanghoon Shin, Jesse M. Zaretsky, Helena Escuin-Ordinas, Angel Garcia-Diaz, Siwen Hu-Lieskovan, Anusha Kalbasi, Catherine S. Grasso, Willy Hugo, Salemiz Sandova...> ;Cancer Discovery. 2017 Feb 1
• 2030 citations
  Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
  , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;The New England Journal of Medicine. 2016 Jul 13
• Human Epidermal Growth Factor Receptor 2 (HER-2/neu)-Directed Therapy for Rare Metastatic Epithelial Tumors with HER-2 Amplification.
  Shin DS, Sherry T, Kallen ME, Wong S, Drakaki A> ;Case reports in oncology. 2016-06-11
• 228 citations
  Repurposing metformin for cancer treatment: current clinical studies
  Young Kwang Chae, Ayush Arya, Mary-Kate Malecek, Daniel Sanghoon Shin, Benedito A. Carneiro, Sunandana Chandra, Jason B. Kaplan, Aparna Kalyan, Jessica K. Altman, Leon...> ;Oncotarget. 2016 Mar 19
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Journal Articles

• Dysregulation of hsa-miR-34a and hsa-miR-449a leads to overexpression of PACS-1 and loss of DNA damage response (DDR) in cervical cancer  
  Mysore S Veena, Santanu Raychaudhuri, Saroj K Basak, Natarajan Venkatesan, Parameet Kumar, Roopa Biswas, Rita Chakrabarti, Jing Lu, Trent Su, Marcus Gallagher-Jones, M..., Journal of Biological Chemistry, 12/11/2020
• Conserved interferon-γ signaling drives clinical response to immune checkpoint blockade therapy in melanoma  
  Catherine S Grasso, Jennifer Tsoi, Mykola Onyshchenko, Gabriel Abril-Rodriguez, Petra Ross-Macdonald, Megan Wind-Rotolo, Ameya Champhekar, Egmidio Medina, Davis Y Torr..., Cancer Cell, 10/12/2020
• A randomized, phase 1, placebo‐controlled trial of APG‐157 in oral cancer demonstrates systemic absorption and an inhibitory effect on cytokines and tumor‐associated m...  
  Saroj K Basak, Alakesh Bera, Alexander J Yoon, Marco Morselli, Chan Jeong, Anela Tosevska, Tien S Dong, Michael Eklund, Eric Russ, Hassan Nasser, Venu Lagishetty, Rong..., Cancer, 4/15/2020
• Clinical features and outcomes of immune checkpoint inhibitor–associated AKI: a multicenter study  
  Frank B Cortazar, Zoe A Kibbelaar, Ilya G Glezerman, Ala Abudayyeh, Omar Mamlouk, Shveta S Motwani, Naoka Murakami, Sandra M Herrmann, Sandhya Manohar, Anushree C Shir..., Journal of the American Society of Nephrology: JASN, 1/2/2020
• Global alteration of T-lymphocyte metabolism by PD-L1 checkpoint involves a block of de novo nucleoside phosphate synthesis  
  Nicolaos Jay Palaskas, Jacob David Garcia, Roksana Shirazi, Daniel Sanghoon Shin, Cristina Puig-Saus, Daniel Braas, Antoni Ribas, Thomas Glen Graeber, Cell discovery, 11/26/2019
• Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation  
  Srinivas Aluri, Rongbao Zhao, Kai Lin, Daniel Sanghoon Shin, Andras Fiser, I David Goldman, Journal of Biological Chemistry, 5/2019
• Genetic mechanisms of immune evasion in colorectal cancer  
  Catherine S Grasso, Marios Giannakis, Daniel K Wells, Tsuyoshi Hamada, Xinmeng Jasmine Mu, Michael Quist, Jonathan A Nowak, Reiko Nishihara, Zhi Rong Qian, Kentaro Ina..., Cancer Discovery, 6/1/2018
• Interferon receptor signaling pathways regulating PD-L1 and PD-L2 expression  
  Angel Garcia-Diaz, Daniel Sanghoon Shin, Blanca Homet Moreno, Justin Saco, Helena Escuin-Ordinas, Gabriel Abril Rodriguez, Jesse M Zaretsky, Lu Sun, Willy Hugo, Xiaoya..., Cell Reports, 5/9/2017
• Mutations associated with acquired resistance to PD-1 blockade in melanoma  
  Jesse M Zaretsky, Angel Garcia-Diaz, Daniel S Shin, Helena Escuin-Ordinas, Willy Hugo, Siwen Hu-Lieskovan, Davis Y Torrejon, Gabriel Abril-Rodriguez, Salemiz Sandoval,..., NEJM, 9/2016
• The evolution of checkpoint blockade as a cancer therapy: what's here, what's next?  
  Daniel Sanghoon Shin, Antoni Ribas, Current Opinion in Immunology, 2015
• Role of the fourth transmembrane domain in proton-coupled folate transporter function as assessed by the substituted cysteine accessibility method  
  Daniel Sanghoon Shin, Rongbao Zhao, Andras Fiser, I David Goldman, American Journal of Physiology-Cell Physiology, 6/15/2013
• Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1)  
  Rongbao Zhao, Daniel Sanghoon Shin, Andras Fiser, I David Goldman, American Journal of Physiology-Cell Physiology, 9/15/2012
• A P425R mutation of the proton-coupled folate transporter causing hereditary folate malabsorption produces a highly selective alteration in folate binding  
  Daniel Sanghoon Shin, Rongbao Zhao, Enghui H Yap, Andras Fiser, I David Goldman, American Journal of Physiology-Cell Physiology, 5/1/2012
• Membrane topological analysis of the proton-coupled folate transporter (PCFT-SLC46A1) by the substituted cysteine accessibility method  
  Rongbao Zhao, Ersin Selcuk Unal, Daniel Sanghoon Shin, I David Goldman, Biochemistry, 4/6/2010
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Abstracts/Posters

• Impact of a pathologist-driven molecular testing protocol on veterans with non-small cell lung cancer
  Rui Li, M Carmen Frias Kletecka, Daniel Sanghoon Shin, ASCO Annual Meeting 2023, abstract_ePoster, 5/31/2023
• Enhanced tumor control with a combination of APG-157 and immune checkpoint inhibitors for head and neck cancer
  Daniel Sanghoon Shin, Saroj K Basak, Mysore S Veena, Begoña Comin-Anduix, Arjun Bhattachrya, Tien Dong, Luis Z Avila, Marilene Wang, Eri Srivatsan, ASCO Annual Meeting 2022, Chicago, IL, 6/2/2022
• Phenotypic characteristics of T cells co-expressing SOX2, OCT3/4, and NANOG
  9. Michael Cerniglia, Helena Escuin-Ordinas,,Caroline Porter, Maria Aleshin, Gardenia Cheung-Lau, ZoranGalic, Inbal, Daniel Sanghoon Shin, Oritz Rosenblatt-Rosen, Anto..., Cancer Research, 2021
• Inverse relationship between Giant Axonal Neuropathy gene expression and EMT in human tumors
  8. Mysore S. Veena, Daniel Sanghoon Shin, Chan Jeong, Jenna R. Chatoff, Natarajan Venkatesan, Saroj K. Basak, David Gray, Sharon P. Wilczysnki3 Steven J. Gray, Donald ..., Cancer Research, 2020
• Immunoediting in untreated mismatch repair deficient colorectal cancer
  6. Catherine Grasso, Marios Giannakis, Daniel Wells, David Wheeler, Eve Shinbrot, Syed Zaidi, Jeroen Huyghe, Milan Geybels, Stephen Salipante, Gabriel Abril-Rodriguez,..., Molecular Cancer Therapeutics, 1/2018
• Loss of adaptive PD-L1 expression is associated with upregulation of PBRM1 chromatin regulator in melanoma
  7. Daniel Sanghoon Shin, Chen Cheng, Nhat Truong, Mykola Onyshchenko, Gabriel Abril-Rodriguez, Catherine Grasso, Begonya Comin-Anduix, Sk Kurdistani, Antoni Ribas, J Clin Oncol, 2018
• Interrogating resistance mechanisms to PD-1 blockade therapy with CRISPR
  4. Davis Yuri Torrejon, Jesse Meir Zaretsky, Daniel Sanghoon Shin, Mykola Onyshchenko, Gabriel Abril-Rodriguez, Agustin Vega-Crespo, Cristina Puig-Saus, Gardenia Cheun..., Journal of Clinical Oncology, 2017
• Abstract NG04: Mechanisms of resistance to anti-PD-1 immunotherapy through interferon pathway mutations
  5. Jesse Zaretsky, Angel Garcia-Diaz, Daniel S Shin, Helena Escuin-Ordinas, Willy Hugo, Siwen Hu-Lieskovan, Zeynep Eroglu, Davis Y Torrejon, Paul C Tumeh, Roger S Lo, ..., Cancer Research, 2017
• 2015 SITC abstract: Innate resistance of PD-1 blockade through loss of function mutations in JAK resulting in inability to express PD-L1 upon interferon exposure
  3. Daniel Sanghoon Shin, Angel Garcia-Diaz, Jesse Zaretsky, Helena Escuin-Ordinas, Siwen Hu-Lieskovan, Nicolaos J Palaskas, Willy Hugo, Marie Sara Komenan, Bartosz Chm..., Journal for Immunotherapy of Cancer, 11/2015
• 2015 SMR Congress abstract: JAK2, STAT1 and 3 and IRF1 are the key signaling molecules from the interferon receptor to regulate PD-L1 and PD-L2 expression
  2. Angel Garcia, Daniel Sanghoon Shin, Blanca Homet Moreno, Helena Escuin-Ordinas, Justin Saco, Siwen Hu-Lieskovan, Lidia Robert, Jesse Zaretsky, Beata Berent-Maoz, Gi..., Pigment Cell & Melanoma Research, 10/2015
• Abstract 5013: Toward better selection of PD-1 blockade responders through direct markers of adaptive immune resistance
  1. Daniel Sanghoon Shin, Angel Garcia-Diaz, Helena Escuin-Ordinas, Nicolaos J. Palaskas, Sara M. Komenan, Thomas G. Graeber, Begonya Comin-Anduix, Antoni Ribas, Cancer Research, 8/2015
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