An open label phase I/II study of cyclophosphamide, bortezomib, pegylated liposomal doxorubicin and dexamethasone in newly diagnosed myeloma
Nishihori T, Baz R, Shain K, Kim J, Ochoa-Bayona JL, Yue B, Sullivan D, Dalton W, Alsina M, Eur J Haematol, 1/20/2015Randomized trial of oral cyclophosphamide and veliparib in high-grade serous ovarian, primary peritoneal, or fallopian tube cancers, or BRAC-mutant ovarian cancer
Kummar S, Oza AM, Fleming GF, Sullivan DM, Gandara DR, Naughton MJ, Villalona-Calero MA, Morgan RJ, Szabo P, Youn A, Chen AP, Ji J, Allen DE, Lih C-J, Mehaffey MG, Wal..., Clin Cancer Res, 1/1/2015Selective nuclear export inhibitor KPT-330 enhances the antitumor activity of gemcitabine in human pancreatic cancer
Kazim S, Malafa MP, Coppola D, Husain K, Zibadi S, Kashyap T, Crochiere M, Landesman Y, Rashal T, Sullivan DM, Mahipal A, Mol Cancer Ther, 1/1/2015A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors
Soliman HH, Jackson E, Neuger T, Dees EC, Harvey RD, Han H, Ismail-Khan R, Minton S, Vahanian NN, Link C, Sullivan DM, Antonia S, Oncotarget, 1/30/2014Interrogating two schedules of the AKT inhibitor MK-2206 in patients with advanced solid tumors incorporating novel pharmacodynamic and functional imaging biomarkers
Yap TA, Yan L, Patnaik A, Tunariu N, Biondo A, Fearen I, Papadopoulos K, Olmos D, Baird R, Delgado L, Tetteh E, Beckman R, Lupinacci L, Riisnaes R, Decordova S, Heaton..., Clin Cancer Res, 1/15/2014Phase I trial of bortezomib (PS-341; NSC 681239) and "non-hybrid"(bolus) infusion schedule of alvocidib (flavopiridol; NSC 649890) in patients with recurrent or refrac...
Holkova B, Kmieciak M, Perkins EB, Bose P, Baz RC, Roodman GD, Stuart RK, Ramakrishnan V, Wan W, Peer CJ, Dawson J, Kang L, Honeycutt C, Tombes MB, Shrader E, Weir-Wig..., Clin Cancer Res, 1/15/2014A parallel-arm phase I trial of the humanized anti-IGF-1R antibody Dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor Ridaforolimus, or the ...
Brana I, Berger R, Golan T, Haluska P, Edenfield J, Fiorica J, Stephenson J, Martin L, Westin S, Hanjani P, Jones MB, Almhanna K, Wenham RM, Sullivan DM, Dalton WS, Gu..., Br J Cancer, 1/11/2014Phase 1 trial of the oral AKT inhibitor MK-2206 plus carboplatin/paclitaxel, docetaxel, or erlotinib in patients with advanced solid tumors
Molife LR, Yan L, Vitfell-Rasmussen J, Zernhelt AM, Sullivan DM, Cassier PA, Chen E, Biondo A, Tetteh E, Siu LL, Patnaik A, Papadopoulos KP, de Bono JS, Tolcher AW, Mi..., J Hematol Oncol, 1/3/2014Phase II study of pegylated liposomal doxorubicin, low-dose dexamethasone, and lenalidomide in patients with newly diagnosed multiple myeloma
Baz RC, Shain KH, Hussein MA, Lee JH, Sullivan DM, Oliver EF, Nardelli LA, Nodzon LA, Zhao X, Ochoa-Bayona JL, Nishihori T, Dalton WS, Alsina M, Am J Hematol, 1/1/2014Inhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agents
Turner JG, Dawson J, Cubitt CL, Baz R, Sullivan DM, Semin Cancer Biol, 1/1/2014A phase I study evaluating the combination of an allosteric AKT inhibitor (MK-2206) and Trastuzumab in patients with HER2-positive solid tumors
Hudis C, Swanton C, Janjigian YY, Lee R, Sutherland S, Lehman R, Chandarlapaty S, Hamilton N, Gajria D, Knowles J, Shah J, Shannon K, Tetteh E, Sullivan DM, Moreno C, ..., Breast Cancer Res, 1/19/2013MK-2206, an AKT inhibitor, enhances carboplatinum/paclitaxel efficacy in gastric cancer cell lines
Almhanna K, Cubitt CL, Zhang S, Kazim S, Sullivan D, Sebti S, Malafa M, Cancer Biol Ther, 1/5/2013Implementation of Timeline Reforms Significantly Speeds Up Initiation of NCI-sponsored Trials
Abrams JS, Mooney M, Zwiebel J, Korn E, Friedman S, Finnigan S, Schettino P, Denicoff A, Kruhm M, Montello M, Misra R, Ansher S, DiPiazza K, Souhan E, Wickerham D, Gia..., J Natl Cancer Inst, 1/1/2013Allogeneic hematopoietic cell transplantation for consolidation of VGPR or CR for newly diagnosed multiple myeloma
Nishihori T, Ochoa-Bayona JL, Kim J, Pidala J, Shain K, Baz R, Sullivan D, Jim HS, Anasetti C, Alsina M, Bone Marrow Transplant, 1/1/2013Phase I study of pomalidomide MTD, safety and efficacy in patients with refractory multiple myeloma who have received lenalidomide and bortezomib
Richardson P, Siegel D, Baz R, Kelley SL, Munshi NC, Laubach J, Sullivan D, Alsina M, Schlossman R, Ghobrial IM, Doss D, Loughney N, McBride L, Bilotti E, Anand P, Nar..., Blood, 1/1/2013Sequence of Novel Agents in Multiple Myeloma: An Instrumental Variable Analysis
Baz R, Miladinovic B, Patel A, Ho VQ, Shain KH, Alsina M, Nishihori T, Ochoa-Bayona JL, Sullivan DM, Dalton WS, Djulbegovic B, Leuk Res, 1/1/2013CRM1 inhibition sensitizes drug resistant human myeloma cells to topoisomerase II and proteasome inhibitors both in vivo and ex vivo
Turner JG, Dawson J, Emmons MF, Cubitt CL, Kauffman M, Shacham S, Hazlehurst LA, Sullivan DM, J Cancer, 1/1/2013Maximally tolerated busulfan systemic exposure in combination with fludarabine as conditioning before allogeneic hematopoietic cell transplantation
Perkins JB, Kim J, Anasetti C, Fernandez HF, Perez LE, Ayala E, Kharfan-Dabaja MA, Tomblyn MR, Sullivan DM, Pidala JA, Field TL, Biol Blood Marrow Transplant, 1/1/2012Bortezomib salvage followed by a Phase I/II study of bortezomib plus high-dose melphalan and tandem autologous transplantation for patients with primary resistant myeloma
Nishihori T, Alekshun TJ, Shain K, Sullivan DM, Baz R, Perez L, Pidala J, Kharfan-Dabaja MA, Ochoa-Bayona JL, Fernandez HF, Yarde DN, Oliveira V, Fulp W, Han G, Kim J,..., Br J Haematol, 1/1/2012A phase II study of RO4929097 in metastatic colorectal cancer
Strosberg JR, Yeatman T, Weber J, Coppola D, Schell MJ, Han G, Almhanna K, Kim R, Valone T, Jump H, Sullivan D, Eur J Cancer, 1/1/2012Nuclear export of proteins and drug resistance in cancer
Turner JG, Dawson J, Sullivan DM, Biochem Pharmacol, 1/1/2012A single supratherapeutic dose of ridaforolimus does not prolong the QTc interval in patients with advanced cancer
Lush R, Patnaik A, Sullivan D, Papadopoulos K, Trucksis M, McCrea J, Cerchio K, Li X, Stroh M, Selverian D, Orford K, Ebbinghaus S, Agrawal N, Iwamoto M, Wagner JA, To..., Cancer Chemother Pharmacol, 1/1/2012Autophagy induced by conventional chemotherapy mediates tumor cell sensitivity to immunotherapy
Ramakrishnan R, Huang C, Cho HI, Lloyd M, Johnson J, Ren X, Altiok S, Sullivan D, Weber J, Celis E, Gabrilovich DI, Cancer Res, 1/1/2012The creation of an integrated health-information platform: building the framework to support personalized medicine
Wenham RM, Sullivan DM, Hulse M, Jacobsen PB, Dalton WS, Personalized Medicine, 1/1/2012Gamma-secretase inhibitor enhances the cytotoxic effect of bortezomib in multiple myeloma
Chen F, Pisklakova A, Li M, Baz R, Sullivan DM, Nefedova Y, Cell Oncol (Dordr), 1/1/2011- Join now to see all