DanielFellerVatnerMDPhD

PubMed

• Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 deficiency and over...
  Sakuma, I., Gaspar, R., Luukkonen, P., Kahn, M., Zhang, D., Murray, S., Golla, J., Shulman, G., Zhang, X., Vatner, D., Samuel, V., Petersen, K.> ;Proceedings of the National Academy of Sciences of the United States of America. 2023 Dec 26
• Fatty Acid Esterification as a NASH Therapeutic Target.
  Ikki Sakuma, Daniel F Vatner> ;Cellular and Molecular Gastroenterology and Hepatology. 2024 Jan 1
• 8 citations
  Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions.
  Eleanna Kaffe, Manolis Roulis, Jun Zhao, Rihao Qu, Esen Sefik, Haris Mirza, Jing Zhou, Yunjiang Zheng, Georgia Charkoftaki, Vasilis Vasiliou, Daniel F Vatner, Wajahat ...> ;Cell. 2023 Aug 31
• 3 citations
  Rising NAFLD and metabolic severity during the Sars-CoV-2 pandemic among children with obesity in the United States.
  Aaron L Slusher, Pamela Hu, Stephanie Samuels, Fuyuze Tokoglu, Jessica Lat, Zhongyao Li, Michele Alguard, Jordan Strober, Daniel Vatner, Veronika Shabanova, Sonia Caprio> ;Obesity. 2023 May 1
• 5 citations
  Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity.
  Anika K Anam, Katherine M Cooke, Milana Bochkur Dratver, Jane V O'Bryan, Lauren E Perley, Seth M Guller, Janice J Hwang, Hugh S Taylor, Leigh Goedeke, Harvey J Kliman,...> ;Molecular Metabolism. 2022 Oct 1
• 32 citations
  Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis.
  Traci E LaMoia, Gina M Butrico, Hasini A Kalpage, Leigh Goedeke, Brandon T Hubbard, Daniel F Vatner, Rafael C Gaspar, Xian-Man Zhang, Gary W Cline, Keita Nakahara, Seu...> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Mar 8
• Publisher Correction: Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance.
  Tina Schumann, Jörg König, Christian von Loeffelholz, Daniel F. Vatner, Dongyan Zhang, Rachel J. Perry, Michel Bernier, Jason Chami, Christine Henke, Anica Kurzbach, N...> ;Communications Biology. 2021 Jul 14
• 6 citations
  Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance
  Tina Schumann, Jörg König, Christian von Loeffelholz, Daniel F. Vatner, Dongyan Zhang, Rachel J. Perry, Michel Bernier, Jason Chami, Christine Henke, Anica Kurzbach, N...> ;Communications Biology. 2021 Jul 1
• 12 citations
  Insulin-stimulated endoproteolytic TUG cleavage links energy expenditure with glucose uptake
  Estifanos N. Habtemichael, Don T. Li, Joao Paulo Camporez, Xavier O. Westergaard, Chloe I. Sales, Xinran Liu, Francesc López-Giráldez, Stephen G. DeVries, Hanbing Li, ...> ;Nature Metabolism. 2021 Mar 1
• 35 citations
  Hepatic Insulin Resistance Is Not Pathway Selective in Humans With Nonalcoholic Fatty Liver Disease
  Kasper W. ter Horst, Daniel F. Vatner, Dongyan Zhang, Gary W. Cline, Mariëtte T. Ackermans, Aart J. Nederveen, Joanne Verheij, Ahmet Demirkiran, Bart A. van Wagensveld...> ;Diabetes Care. 2021 Feb 1
• 63 citations
  Mechanisms by which adiponectin reverses high fat diet-induced insulin resistance in mice.
  Xiruo Li, Dongyan Zhang, Daniel F. Vatner, Leigh Goedeke, Sandro M. Hirabara, Ye Zhang, Rachel J. Perry, Gerald I. Shulman> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Dec 22
• 5 citations
  Membrane-bound-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice.
  Abudukadier Abulizi, Daniel F Vatner, Zhang Ye, Yongliang Wang, Joao-Paulo Camporez, Dongyan Zhang, Mario Kahn, Kun Lyu, Alaa Sirwi, Gary W Cline, M Mahmood Hussain, P...> ;Journal of Lipid Research. 2020 Dec 1
• 43 citations
  Metabolic control analysis of hepatic glycogen synthesis in vivo.
  Yuichi Nozaki, Max C. Petersen, Dongyan Zhang, Daniel F. Vatner, Rachel J. Perry, Abudukadier Abulizi, Sofie Haedersdal, Xian-Man Zhang, Gina M. Butrico, Varman T. Sam...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Apr 7
• 6 citations
  Considering the Links Between Nonalcoholic Fatty Liver Disease and Insulin Resistance: Revisiting the Role of Protein Kinase C ε
  Varman T. Samuel, Max C. Petersen, Brandon M. Gassaway, Daniel F. Vatner, Jesse Rinehart, Gerald I. Shulman> ;Hepatology. 2019 Dec 1
• 8 citations
  Adipose glucocorticoid action influences whole-body metabolism via modulation of hepatic insulin action
  Abudukadier Abulizi, Joao Paulo Camporez, Michael J. Jurczak, Kasper F. Høyer, Dongyan Zhang, Gary W. Cline, Varman T. Samuel, Gerald I. Shulman, Daniel F. Vatner> ;FASEB Journal. 2019 Apr 28
• 9 citations
  Ectopic lipid deposition mediates insulin resistance in adipose specific 11β-hydroxysteroid dehydrogenase type 1 transgenic mice.
  Abudukadier Abulizi, Joao Paulo Camporez, Dongyan Zhang, Varman T. Samuel, Gerald I. Shulman, Daniel F. Vatner> ;Metabolism. 2019 Apr 1
• 1 citations
  Author Correction: Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo
  Anila K. Madiraju, Yang Qiu, Rachel J. Perry, Yasmeen Rahimi, Xian-Man Zhang, Dongyan Zhang, Joao Paulo Camporez, Gary W. Cline, Gina M. Butrico, Bruce E. Kemp, Gregor...> ;Nature Medicine. 2019 Mar 1
• 5 citations
  PEPCK1 Antisense Oligonucleotide Prevents Adiposity and Impairs Hepatic Glycogen Synthesis in High-Fat Male Fed Rats.
  Sara A. Beddow, Arijeet K. Gattu, Daniel F. Vatner, Lauren Paolella, Abdulelah Alqarzaee, Nedda Tashkandi, Violeta B. Popov, Christopher D. Church, Matthew S. Rodeheff...> ;Endocrinology. 2019 Jan 1
• 167 citations
  Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo.
  Anila K. Madiraju, Yang Qiu, Rachel J. Perry, Yasmeen Rahimi, Xian-Man Zhang, Dongyan Zhang, Joao Paulo Camporez, Gary W. Cline, Gina M. Butrico, Bruce E. Kemp, Gregor...> ;Nature Medicine. 2018 Jul 23
• 151 citations
  Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents.
  Leigh Goedeke, Jamie Bates, Daniel F. Vatner, Rachel J. Perry, Ting Wang, Ricardo Ramirez, Li Li, Matthew W. Ellis, Dongyan Zhang, Kari E. Wong, Carine Beysen, Gary W....> ;Hepatology. 2018 Dec 1
• 5 citations
  In vivo studies on the mechanism of methylene cyclopropyl acetic acid and methylene cyclopropyl glycine-induced hypoglycemia.
  Yang Qiu, Rachel J. Perry, Joao Paulo Camporez, Xian-Man Zhang, Mario Kahn, Gary W. Cline, Gerald I. Shulman, Daniel F. Vatner> ;The Biochemical Journal. 2018 Mar 30
• 81 citations
  Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis
  Binod Aryal, Abhishek Singh, Xinbo Zhang, Luis Varela, Noemi Rotllan, Leigh Goedeke, Balkrishna Chaube, Joao Paulo Camporez, Daniel F. Vatner, Tamas L. Horvath, Gerald...> ;JCI Insight. 2018 Mar 22
• 46 citations
  Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents
  Daniel F. Vatner, Leigh Goedeke, Joao Paulo Camporez, Kun Lyu, Ali Nasiri, Dongyan Zhang, Sanjay Bhanot, Susan Murray, Glenn S. Gerhard, Gerald I. Shulman, Varman T. S...> ;Diabetologia. 2018 Mar 1
• 583 citations
  Regulation of hepatic glucose metabolism in health and disease
  Max C. Petersen, Daniel F. Vatner, Gerald I. Shulman> ;Nature Reviews. Endocrinology. 2017 Jul 21
• 106 citations
  Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
  Kasper W. ter Horst, Pim W. Gilijamse, Ruth I. Versteeg, Mariëtte T. Ackermans, Aart J. Nederveen, Susanne E. la Fleur, Johannes A. Romijn, Max Nieuwdorp, Dongyan Zhan...> ;Cell Reports. 2017 Jun 6
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Journal Articles

• PEPCK1 Antisense Oligonucleotide Prevents Adiposity and Impairs Hepatic Glycogen Synthesis in High-Fat Male Fed Rats  
  Arijeet K Gattu, Varman T Samuel, Violeta Popov, Daniel F Vatner, Gary Cline, Endocrinology
• Metformin Inhibits Gluconeogenesis via a Redox-Dependent Mechanism in Vivo  
  Kitt F Petersen, Daniel F Vatner, Gerald I Shulman, Nature

Lectures

• 3,5-Diiodo-L-Thyronine Improves Hepatic Insulin Sensitivity but Not NAFLD in Fat-Fed Rats 
  New Haven, CT - 6/16/2014