DanielleN.MargalitMD

Head & Neck

Associate Professor of Radiation Oncology, Harvard Medical School Staff Physician, Dana-Farber Cancer Institute and Brigham and Women's Hospital

Join to view full profile

Dr. Margalit is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Margalit's full profile

Already have an account?

Office
450 Brookline Ave
Boston, MA 02215
Phone+1 617-632-3591
Is this information wrong?

Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Radiation Oncology, 2007 - 2011
Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Radiation Oncology, 2006 - 2010
Brigham and Women's HospitalResidency, Internal Medicine, 2006 - 2007
Harvard Medical SchoolClass of 2006

Certifications & Licensure

ME State Medical License 2020 - 2025
MA State Medical License 2008 - 2024
American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2012

Clinical Trials

Safety Study of Afatinib and Postoperative Radiation Therapy to Treat Head and Neck Cancer Start of enrollment: 2013 Feb 01
Completed
Phase 1
Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma Start of enrollment: 2019 May 20
Recruiting
Not Applicable

Publications & Presentations

PubMed

Carotid Artery Stenosis and Ischemic Stroke in Patients with Head and Neck Cancer Treated with Radiotherapy: A Critical Review.
Justin Smith, Jonathan Golledge, Domenico Nastasi, Lachlan McDowell, Danielle Margalit, Anju Nohria> ;International Journal of Radiation Oncology, Biology, Physics. 2024 Apr 5
Outcomes of palliative radiation therapy for cutaneous squamous cell carcinoma: A retrospective cohort study.
Kim, E., Granger, E., Silk, A., Schoenfeld, J., Margalit, D., Tishler, R., Ruiz, E.> ;JAAD International. 2024 Mar 1
Neoadjuvant chemotherapy for advanced oral cavity cancer.
Yaniv, D., Barbon, C., Smith, J., Gross, N., Seiwert, T., Margalit, D., Williams, M., Largo, R.> ;CA. 2024 Feb 8
Imaging and Biomarker Surveillance for Head and Neck Squamous Cell Carcinoma: A Systematic Review and AUC Document.
Bain, P., Ward, M., Hu, K., Witek, M., Bakst, R., Chandra, R., Hanna, G., Chang, S., Siddiqui, F., Takiar, V., Shukla, M., Robbins, J., Galloway, T., Margalit, D.> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Dec 31
Definitive radiation therapy for inoperable stage III/IV cutaneous squamous cell carcinoma: A single-institution retrospective cohort study.
Emily E Granger, Emily Y Kim, Emily E Karn, Morgan K Groover, Ann W Silk, Danielle N Margalit, Roy B Tishler, Jonathan D Schoenfeld, Emily S Ruiz> ;Journal of the American Academy of Dermatology. 2024 Jan 1
7 citations
Development and Validation of an Automated Image-Based Deep Learning Platform for Sarcopenia Assessment in Head and Neck Cancer.
Zezhong Ye, Anurag Saraf, Yashwanth Ravipati, Frank Hoebers, Paul J Catalano, Yining Zha, Anna Zapaishchykova, Jirapat Likitlersuang, Christian Guthier, Roy B Tishler,...> ;JAMA Network Open. 2023 Aug 1
The Interplay Between Radiation Dose, Volume, and Systemic Therapy.
David J Thomson, Christina Henson, Shao Hui Huang, Lachlan J McDowell, Michelle Mierzwa, Christopher Wilke, Danielle N Margalit> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Aug 1
10 citations
Screening for extranodal extension in HPV-associated oropharyngeal carcinoma: evaluation of a CT-based deep learning algorithm in patient data from a multicentre, rand...
Benjamin H Kann, Jirapat Likitlersuang, Dennis Bontempi, Zezhong Ye, Sanjay Aneja, Richard Bakst, Hillary R Kelly, Amy F Juliano, Sam Payabvash, Jeffrey P Guenette, Ra...> ;The Lancet. Digital Health. 2023 Jun 1
Fully-automated sarcopenia assessment in head and neck cancer: development and external validation of a deep learning pipeline.
Zezhong Ye, Anurag Saraf, Yashwanth Ravipati, Frank Hoebers, Yining Zha, Anna Zapaishchykova, Jirapat Likitlersuang, Roy B Tishler, Jonathan D Schoenfeld, Danielle N M...> ;Medrxiv. 2023 Mar 6
20 citations
Association of Pretreatment Circulating Tumor Tissue-Modified Viral HPV DNA With Clinicopathologic Factors in HPV-Positive Oropharyngeal Cancer.
Eleni M Rettig, Annette A Wang, Ngoc-Anh Tran, Evan Carey, Tanujit Dey, Jonathan D Schoenfeld, Kartik Sehgal, Jeffrey P Guenette, Danielle N Margalit, Rosh Sethi, Ravi...> ;JAMA Otolaryngology-- Head & Neck Surgery. 2022 Dec 1
2 citations
Interventions for head and neck cancer survivors: Systematic review.
Danielle N Margalit, Talya Salz, Rebecca Venchiarutti, Kristi Milley, Mairead McNamara, Sophie Chima, Jamieson Wong, Paige Druce, Larissa Nekhlyudov> ;Head & Neck. 2022 Nov 1
16 citations
Retreatment of Recurrent or Second Primary Head and Neck Cancer After Prior Radiation: Executive Summary of the American Radium Society Appropriate Use Criteria.
Matthew C Ward, Shlomo A Koyfman, Richard L Bakst, Danielle N Margalit, Beth M Beadle, Jonathan J Beitler, Steven Shih-Wei Chang, Jay S Cooper, Thomas J Galloway, John...> ;International Journal of Radiation Oncology, Biology, Physics. 2022 Jul 15
13 citations
Adjuvant radiation following clear margin resection of high T-stage cutaneous squamous cell carcinoma halves the risk of local and locoregional recurrence: A dual-cent...
Emily S Ruiz, Kylee J B Kus, Timothy D Smile, Fadi Murad, Guohai Zhou, Evelyn O Ilori, Jonathan D Schoenfeld, Danielle N Margalit, Roy B Tishler, Allison T Vidimos, Sh...> ;Journal of the American Academy of Dermatology. 2022 Jul 1
A Bit More Here and a Little Less There: The Trials (and Tribulations) of Adjuvant and Neoadjuvant Head and Neck Studies in 2021.
Lachlan McDowell, Melvin L K Chua, Beth M Beadle, Daniel J Ma, Michelle Mierzwa, David J Thomson, Danielle N Margalit> ;International Journal of Radiation Oncology, Biology, Physics. 2022 Jun 1
2 citations
Association between radiation dose to organs at risk and acute patient reported outcome during radiation treatment for head and neck cancers.
Mona Arbab, Yu-Hui Chen, Roy B Tishler, Lauren Gunasti, Jason Glass, Jo Ann Fugazzotto, Joseph H Killoran, Rosh Sethi, Eleni Rettig, Donald Annino, Laura Goguen, Ravin...> ;Head & Neck. 2022 Jun 1
4 citations
Characterization of clinical outcomes after shorter course hypofractionated and standard-course radiotherapy for stage I-III curatively-treated Merkel cell carcinoma.
Kevin X Liu, Michael G Milligan, Jonathan D Schoenfeld, Roy B Tishler, Andrea K Ng, Phillip M Devlin, Elliott Fite, Guilherme Rabinowits, Glenn J Hanna, Ann W Silk, Ch...> ;Radiotherapy and Oncology. 2022 Aug 1
3 citations
Oligometastatic adenoid cystic carcinoma: Correlating tumor burden and time to treatment with outcomes.
Kevin Tyan, Ji Eun Bae, Danielle N Margalit, Roy B Tishler, Mai Anh Huynh, Vickie Y Jo, Robert I Haddad, Nicole G Chau, Glenn J Hanna, Jonathan D Schoenfeld, Lorch, J.> ;Head & Neck. 2022 Mar 1
43 citations
Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck.
, , , , , , , , , , , , , , , , , , , , , , , > ;Clinical Cancer Research. 2021 Oct 19
Something for Everyone From Low-Risk to High-Risk: 5 Recent Studies to Improve Treatment and Surveillance for All Patients With Squamous Cell Carcinoma of the Head and...
Michelle Mierzwa, Beth M. Beadle, Melvin L.K. Chua, Daniel J. Ma, David J Thomson, Danielle N. Margalit> ;International Journal of Radiation Oncology, Biology, Physics. 2021 Sep 1
3 citations
Epidemiologic distinctions between base of tongue and tonsil oropharyngeal carcinomas.
Melina J. Windon, Carole Fakhry, Danielle N. Margalit, Tanujit Dey, Eleni M. Rettig> ;Head & Neck. 2021 Jul 20
2 citations
Head and Neck Cancer Clinical Research on ClinicalTrials.gov: An Opportunity for Radiation Oncologists.
Vinayak Muralidhar, Nicholas J. Giacalone, N. Milani, Jonathan D. Schoenfeld, Roy B. Tishler, Bhupendra Rawal, Danielle N. Margalit> ;Advances in Radiation Oncology. 2021 May 1
17 citations
A Randomized Phase 2 Study of Pembrolizumab With or Without Radiation in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma.
, , , , , , , , , , , , , , , , , , , , , > ;International Journal of Radiation Oncology, Biology, Physics. 2021 Jan 1
7 citations
Hospitalization rates and 30-day all-cause mortality among head and neck cancer patients and survivors with COVID-19.
Glenn J. Hanna, Eleni M. Rettig, Jong C. Park, Mark A. Varvares, Danielle N. Margalit, Jonathan D. Schoenfeld, Roy B. Tishler, Laura A. Goguen, Donald J. Annino, Rober...> ;Oral Oncology. 2021 Jan 1
6 citations
Systematic review of postoperative therapy for resected squamous cell carcinoma of the head and neck: Executive summary of the American Radium Society appropriate use ...
Danielle N. Margalit, Assuntina G. Sacco, Jay S Cooper, John A. Ridge, Richard L. Bakst, Beth M. Beadle, Jonathan J. Beitler, Steven S. Chang, Allen M. Chen, Thomas J....> ;Head & Neck. 2021 Jan 1
15 citations
Ipsilateral radiation for squamous cell carcinoma of the tonsil: American Radium Society appropriate use criteria executive summary
C. Jillian Tsai, Thomas J. Galloway, Danielle N. Margalit, Richard L. Bakst, Beth M. Beadle, Jonathan J. Beitler, Steven S. Chang, Allen M. Chen, Jay S Cooper, Shlomo ...> ;Head & Neck. 2021 Jan 1
Join now to see all

Press Mentions

High Rates of Oropharynx Cancer Tied to HPVSeptember 11th, 2019
Estimate of the National Burden of HPV-Positive Oropharyngeal Head and Neck CancersAugust 29th, 2019
Adding Nivolumab to Standard First-Line Therapy Feasible in Advanced Head and Neck CancerFebruary 20th, 2018