DavidBarbieMD

PubMed

• Nonpathogenicengineered to surface display cytokines as a new platform for immunotherapy.
  Shaobo Yang, Michal Sheffer, Isabel E Kaplan, Zongqi Wang, Mubin Tarannum, Khanhlinh Dinh, Yasmin Abdulhamid, Roman Shapiro, Rebecca Porter, Robert Soiffer, Jerome Rit...> ;Research Square. 2024 Mar 22
• Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes.
  Varadha Balaji Venkadakrishnan, Adam G Presser, Richa Singh, Matthew A Booker, Nicole A Traphagen, Kenny Weng, Nathaniel C Voss, Navin R Mahadevan, Kei Mizuno, Loredan...> ;Research Square. 2024 Mar 4
• 2 citations
  TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity.
  Tetsuo Tani, Haritha Mathsyaraja, Marco Campisi, Ze-Hua Li, Koji Haratani, Caroline G Fahey, Keiichi Ota, Navin R Mahadevan, Yingxiao Shi, Shin Saito, Kei Mizuno, Tran...> ;Cancer Discovery. 2024 Jan 10
• 1 citations
  Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers.
  Dufva, O., Gandolfi, S., Huuhtanen, J., Dashevsky, O., Duàn, H., Saeed, K., Klievink, J., Nygren, P., Bouhlal, J., Lahtela, J., Näätänen, A., Ghimire, B., Hannunen, T....> ;Immunity. 2023 Dec 12
• Unraveling the Intricacies of CD73/Adenosine Signaling: The Pulmonary Immune and Stromal Microenvironment in Lung Cancer.
  Saigí, M., Mesía-Carbonell, O., Guillamat-Prats, R., Barbie, D.> ;Cancers. 2023 Dec 4
• Patient-Specific Vascularized Tumor Model: Blocking TAM Recruitment with Multispecific Antibodies Targeting CCR2 and CSF-1R.
  Nguyen, H., Gurvich, N., Gillrie, M., Offeddu, G., Humayun, M., Kan, E., Wan, Z., Coughlin, M., Zhang, C., Vu, V., Tan, S., Hsu, J., Kamm, R., Lee, S., Barbie, D.> ;Biorxiv. 2023 Nov 29
• EDIL3 as an Angiogenic Target of Immune Exclusion Following Checkpoint Blockade.
  Saba Tabasum, Dinesh Thapa, Anita Giobbie-Hurder, Jason L Weirather, Marco Campisi, Pieter J Schol, Xiaoyu Li, Jingjing Li, Charles H Yoon, Michael P Manos, David A Ba...> ;Cancer Immunology Research. 2023 Nov 1
• 1 citations
  Development of a Patient-Derived 3D Immuno-Oncology Platform to Potentiate Immunotherapy Responses in Ascites-Derived Circulating Tumor Cells.
  Thomas J Gerton, Allen Green, Marco Campisi, Minyue Chen, Iliana Gjeci, Navin Mahadevan, Catherine A A Lee, Ranjan Mishra, Ha V Vo, Koji Haratani, Ze-Hua Li, Kathleen ...> ;Cancers. 2023 Aug 16
• 1 citations
  Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor-Positive Breast Cancer.
  Francisco Hermida-Prado, Yingtian Xie, Shira Sherman, Zsuzsanna Nagy, Douglas Russo, Tara Akhshi, Zhengtao Chu, Avery Feit, Marco Campisi, Minyue Chen, Agostina Nardon...> ;Cancer Research. 2023 Oct 2
• 7 citations
  ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.
  Ines Mota, Enrico Patrucco, Cristina Mastini, Navin R Mahadevan, Tran C Thai, Elisa Bergaggio, Taek-Chin Cheong, Giulia Leonardi, Elif Karaca-Atabay, Marco Campisi, Te...> ;Nature Cancer. 2023 Jul 1
• 2 citations
  Cotargeting a MYC/eIF4A-survival axis improves the efficacy of KRAS inhibitors in lung cancer.
  Francesca Nardi, Naiara Perurena, Amy E Schade, Ze-Hua Li, Kenneth Ngo, Elena V Ivanova, Aisha Saldanha, Chendi Li, Prafulla C Gokhale, Aaron N Hata, David A Barbie, C...> ;The Journal of Clinical Investigation. 2023 Aug 15
• 4 citations
  Priming a vascular-selective cytokine response permits CD8T-cell entry into tumors.
  Dae Joong Kim, Swetha Anandh, Jamie L Null, Piotr Przanowski, Sanchita Bhatnagar, Pankaj Kumar, Sarah E Shelton, Erin E Grundy, Katherine B Chiappinelli, Roger D Kamm,...> ;Nature Communications. 2023 Apr 14
• 4 citations
  The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells.
  Christopher Noyes, Shunsuke Kitajima, Fengkai Li, Yusuke Suita, Saradha Miriyala, Shakson Isaac, Nagib Ahsan, Erik Knelson, Amir Vajdi, Tetsuo Tani, Tran C Thai, Derek...> ;Communications Biology. 2023 Jan 18
• 26 citations
  Targeting TBK1 to overcome resistance to cancer immunotherapy.
  Yi Sun, Or-Yam Revach, Seth Anderson, Emily A Kessler, Clara H Wolfe, Anne Jenney, Caitlin E Mills, Emily J Robitschek, Thomas G R Davis, Sarah Kim, Amina Fu, Xiang Ma...> ;Nature. 2023 Mar 1
• Distinct Dynamics of Migratory Response to PD-1 and CTLA-4 Blockade Reveals New Mechanistic Insights for Potential T-Cell Reinvigoration following Immune Checkpoint Bl...
  Fateme Safaeifard, Bahram Goliaei, Amir R Aref, Mohammad-Hadi Foroughmand-Araabi, Sama Goliaei, Russell W Jenkins, David A Barbie, Seyed Peyman Shariatpanahi, Curzio R...> ;Cells. 2022 Nov 8
• 9 citations
  New Strategy for Promoting Vascularization in Tumor Spheroids in a Microfluidic Assay.
  Zhengpeng Wan, Marie A Floryan, Mark F Coughlin, Shun Zhang, Amy X Zhong, Sarah E Shelton, Xun Wang, Chenguang Xu, David A Barbie, Roger D Kamm> ;Advanced Healthcare Materials. 2023 Jun 1
• 23 citations
  MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer.
  Shunsuke Kitajima, Tetsuo Tani, Benjamin F Springer, Marco Campisi, Tatsuya Osaki, Koji Haratani, Minyue Chen, Erik H Knelson, Navin R Mahadevan, Jessica Ritter, Ryohe...> ;Cancer Cell. 2022 Oct 10
• 18 citations
  Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes.
  Satyaki Sengupta, Sanjukta Das, Angela C Crespo, Annelisa M Cornel, Anand G Patel, Navin R Mahadevan, Marco Campisi, Alaa K Ali, Bandana Sharma, Jared H Rowe, Hao Huan...> ;Nature Cancer. 2022 Oct 1
• 7 citations
  MET-Induced CD73 Restrains STING-Mediated Immunogenicity of EGFR-Mutant Lung Cancer.
  Ryohei Yoshida, Maria Saigi, Tetsuo Tani, Benjamin F Springer, Hirofumi Shibata, Shunsuke Kitajima, Navin R Mahadevan, Marco Campisi, William Kim, Yoshihisa Kobayashi,...> ;Cancer Research. 2022 Nov 2
• 8 citations
  Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1.
  Hsiao-Yun Chen, Yavuz T Durmaz, Yixiang Li, Amin H Sabet, Amir Vajdi, Thomas Denize, Emily Walton, Yasmin Nabil Laimon, John G Doench, Navin R Mahadevan, Julie-Aurore ...> ;Nature Communications. 2022 Aug 25
• 28 citations
  Dissecting the clinicopathologic, genomic, and immunophenotypic correlates of KRAS-mutated non-small-cell lung cancer.
  B Ricciuti, J V Alessi, A Elkrief, X Wang, A Cortellini, Y Y Li, V R Vaz, H Gupta, F Pecci, A Barrichello, G Lamberti, T Nguyen, J Lindsay, B Sharma, K Felt, S J Rodig...> ;Annals of Oncology. 2022 Oct 1
• 7 citations
  Engineered Microphysiological Systems for Testing Effectiveness of Cell-Based Cancer Immunotherapies.
  Marco Campisi, Sarah E Shelton, Minyue Chen, Roger D Kamm, David A Barbie, Erik H Knelson> ;Cancers. 2022 Jul 22
• 35 citations
  STING activation promotes robust immune response and NK cell-mediated tumor regression in glioblastoma models.
  Gilles Berger, Erik H Knelson, Jorge L Jimenez-Macias, Michal O Nowicki, Saemi Han, Eleni Panagioti, Patrick H Lizotte, Kwasi Adu-Berchie, Alexander Stafford, Nikolaos...> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Jul 12
• 19 citations
  Activation of Tumor-Cell STING Primes NK-Cell Therapy.
  Erik H Knelson, Elena V Ivanova, Mubin Tarannum, Marco Campisi, Patrick H Lizotte, Matthew A Booker, Ismail Ozgenc, Moataz Noureddine, Brittany Meisenheimer, Minyue Ch...> ;Cancer Immunology Research. 2022 Aug 3
• 23 citations
  A Robust Method for Perfusable Microvascular Network Formation In Vitro.
  Zhengpeng Wan, Amy X Zhong, Shun Zhang, Georgios Pavlou, Mark F Coughlin, Sarah E Shelton, Huu Tuan Nguyen, David A Barbie, Roger D Kamm, Lorch, J.> ;Small Methods. 2022 Jun 1
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Journal Articles

• Genomic Correlates of Response to Immune Checkpoint Blockade in Microsatellite-Stable Solid Tumors  
  Jeffrey A Engelman, David A Barbie, Nicole G Chau, Glenn J Hanna, Natalie I Vokes, Sabina Signoretti, Pasi A Janne, Robert I Haddad, Lynette M Sholl, Rizwan Haq, Peter..., Nature
• Tumor Innate Immunity Primed by Specific Interferon-Stimulated Endogenous Retroviruses  
  Scott Rodig, Ewa Sicinska, Thanh Uyen Barbie, David Allen Barbie, Russell William Jenkins, Ravindra Uppaluri, Rohit Thummalapalli, Jacob Sands, Nature