DavidTimothyBergDO

PubMed

• 16 citations
  Levels of protein C and soluble thrombomodulin in critically ill patients with acute kidney injury: a multicenter prospective observational study.
  Josée Bouchard, Rakesh Malhotra, Shamik H. Shah, Yu-ting Kao, Florin Vaida, Akanksha Gupta, David T. Berg, Brian W. Grinnell, Brenda Stofan, Ashita Tolwani, Ravindra L...> ;Plos One. 2015 Mar 19
• 13 citations
  Soluble thrombomodulin reduces inflammation and prevents microalbuminuria induced by chronic endothelial activation in transgenic mice.
  Gangaraju Rajashekhar, Akanksha Gupta, Abby Marin, Jessica L. Friedrich, Antje Willuweit, David T. Berg, Martin S. Cramer, George E. Sandusky, Timothy A. Sutton, David...> ;American Journal of Physiology. Renal Physiology. 2012 Mar 15
• 99 citations
  Soluble Thrombomodulin Protects Ischemic Kidneys
  Asif Sharfuddin, Ruben M. Sandoval, David T. Berg, Grant McDougal, Silvia B. Campos, Carrie L. Phillips, Bryan Edward Jones, Akanksha Gupta, Brian W. Grinnell, Bruce A...> ;Journal of the American Society of Nephrology. 2009 Mar 1
• 37 citations
  Distinct Functions of Activated Protein C Differentially Attenuate Acute Kidney Injury
  Akanksha Gupta, Bruce Gerlitz, Mark Alan Richardson, Christopher Y. S. Bull, David T. Berg, Samreen K. Syed, Elizabeth Galbreath, Barbara A. Swanson, Bryan Edward Jone...> ;Journal of the American Society of Nephrology. 2009 Feb 1
• 18 citations
  Treatment of Sepsis-Induced Acquired Protein C Deficiency Reverses Angiotensin-Converting Enzyme-2 Inhibition and Decreases Pulmonary Inflammatory Response
  Mark A. Richardson, Akanksha Gupta, Lee A. O'Brien, David T. Berg, Bruce Gerlitz, Samreen K. Syed, Ganesh R. Sharma, Martin S. Cramer, Josef G. Heuer, Elizabeth Galbre...> ;The Journal of Pharmacology and Experimental Therapeutics. 2008 Apr 1
• 7 citations
  Activated protein C modulates chemokine response and tissue injury in experimental sepsis.
  Ganesh R. Sharma, Bruce Gerlitz, David T. Berg, Martin S. Cramer, Joseph A. Jakubowski, Elizabeth Galbreath, Josef G. Heuer, Brian W. Grinnell> ;Advances in Experimental Medicine and Biology. 2008 Jan 1
• 50 citations
  Negative Regulation of Inducible Nitric-oxide Synthase Expression Mediated through Transforming Growth Factor-β-dependent Modulation of Transcription Factor TCF11
  David T. Berg, Akanksha Gupta, Mark A. Richardson, Lee A. O'Brien, David Scott Calnek, Brian W. Grinnell> ;The Journal of Biological Chemistry. 2007 Dec 21
• 48 citations
  Activated Protein C Decreases Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand by an EPCR- Independent Mechanism Involving Egr-1/Erk-1/2 Activation
  Lee A. O'Brien, Mark A. Richardson, Sean F. Mehrbod, David T. Berg, Bruce Gerlitz, Akanksha Gupta, Brian W. Grinnell> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2007 Dec 1
• 315 citations
  Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis
  Berend Isermann, Ilya A. Vinnikov, Thati Madhusudhan, S. Herzog, Muhammed Kashif, Janusch Blautzik, Marcus A F Corat, Martin Zeier, Erwin Blessing, Jun Oh, Bruce Gerli...> ;Nature Medicine. 2007 Nov 1
• 7 citations
  Activated protein C suppresses adrenomedullin and ameliorates lipopolysaccharide-induced hypotension
  Akanksha Gupta, David T. Berg, Bruce Gerlitz, Mark A. Richardson, Elizabeth Galbreath, Samreen K. Syed, Avadhesh C. Sharma, Stephen F. Lowry, Brian W. Grinnell> ;Shock. 2007 Oct 1
• 111 citations
  Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2
  Akanksha Gupta, George J. Rhodes, David T. Berg, Bruce Gerlitz, Bruce A. Molitoris, Brian W. Grinnell> ;American Journal of Physiology. Renal Physiology. 2007 Jul 1
• 41 citations
  Role of protein C in renal dysfunction after polymicrobial sepsis
  Akanksha Gupta, David T. Berg, Bruce Gerlitz, Ganesh R. Sharma, Samreen K. Syed, Mark Alan Richardson, George E. Sandusky, Josef G. Heuer, Elizabeth Galbreath, Brian W...> ;Journal of the American Society of Nephrology. 2007 Mar 1
• 9 citations
  FoxA2 involvement in suppression of protein C, an outcome predictor in experimental sepsis.
  David T. Berg, Bruce Gerlitz, Ganesh R. Sharma, Mark A. Richardson, Eddie J. Stephens, Renee L. Grubbs, Kimberly C. Holmes, Kelly A. Fynboe, Dominick Montani, Martin S...> ;Clinical and Vaccine Immunology. 2006 Mar 1
• 24 citations
  NF-κB mediates amyloid β peptide-stimulated activity of the human apolipoprotein E gene promoter in human astroglial cells
  Yansheng Du, Xianming Chen, Xing Wei, Kelly R. Bales, David T. Berg, Steven M. Paul, Martin R. Farlow, Bryan Maloney, Yuan Wen Ge, Debomoy K. Lahiri> ;Brain Research. Molecular Brain Research. 2005 May 20
• 16 citations
  Smad6s Regulates Plasminogen Activator Inhibitor-1 through a Protein Kinase C-β-dependent Up-regulation of Transforming Growth Factor-β
  David T. Berg, Laura Jean Myers, Mark A. Richardson, George E. Sandusky, Brian W. Grinnell> ;The Journal of Biological Chemistry. 2005 Apr 15
• 55 citations
  Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis.
  Josef G. Heuer, Ganesh R. Sharma, Bruce Gerlitz, Tonghai Zhang, Dianna L. Bailey, Chunjin Ding, David T. Berg, Douglas Perkins, Eddie J. Stephens, Kimberly C. Holmes, ...> ;Critical Care Medicine. 2004 Jul 1
• 50 citations
  Engineering the proteolytic specificity of activated protein C improves its pharmacological properties
  David T. Berg, Bruce Gerlitz, Jing Shang, T. C. Smith, Paula Santa, Mark Alan Richardson, Ken D. Kurz, Brian W. Grinnell, Ken Mace, Bryan Edward Jones> ;Proceedings of the National Academy of Sciences of the United States of America. 2003 Apr 15
• 30 citations
  Modulation of thrombomodulin-dependent activation of human protein C through differential expression of endothelial Smads.
  George E. Sandusky, David T. Berg, Mark A. Richardson, Laura Jean Myers, Brian W. Grinnell> ;The Journal of Biological Chemistry. 2002 Dec 20
• 31 citations
  Differential mechanisms of plasminogen activator inhibitor-1 gene activation by transforming growth factor-β and tumor necrosis factor-α in endothelial cells
  Yan Q. Chen, Joanne Sloan-Lancaster, David T. Berg, Mark A. Richardson, Brian W. Grinnell, Julie Tseng-Crank> ;Thrombosis and Haemostasis. 2001 Dec 1
• 17 citations
  17β-Estradiol, But Not Raloxifene, Decreases Thrombomodulin in the Antithrombotic Protein C Pathway
  Mark A. Richardson, David T. Berg, David Scott Calnek, Angelina V. Ciaccia, David E. Joyce, Brian W. Grinnell> ;Endocrinology. 2000 Oct 1
• 38 citations
  Enhanced protein C activation and inhibition of fibrinogen cleavage by a thrombin modulator.
  David T. Berg, Michael R. Wiley, Brian W. Grinnell> ;Science. 1996 Sep 6
• 12 citations
  Trans-repressor BEF-1 Phosphorylation A POTENTIAL CONTROL MECHANISM FOR HUMAN ApoE GENE REGULATION
  David T. Berg, David Scott Calnek, Brian W. Grinnell> ;The Journal of Biological Chemistry. 1996 Mar 1
• 17 citations
  The Human Apolipoprotein E Gene Is Negatively Regulated in Human Liver HepG2 Cells by the Transcription Factor BEF-1
  David T. Berg, David Scott Calnek, Brian W. Grinnell> ;The Journal of Biological Chemistry. 1995 Jun 30
• 17 citations
  IDENTIFICATION OF A REGION IN PROTEIN C INVOLVED IN THROMBOMODULIN-STIMULATED ACTIVATION BY THROMBIN : POTENTIAL REPULSION AT ANION-BINDING SITE I IN THROMBIN
  B W Grinnell, B Gerlitz, D T Berg> ;The Biochemical Journal. 1994 Nov 1
• 4 citations
  Pro to gly (p219g) in a silent glycosylation site results in complete glycosylation in tissue plasminogen activator
  David T. Berg, Brian W. Grinnel> ;Protein Science. 1993 Jan 1
• Join now to see all