DavidEBlairMD

PubMed

• Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors.
  Lockhart DEA, Schuettelkopf A, Blair DE, van Aalten DMF> ;FEBS Lett.. 2014-08-25
• Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function.
  Zanin-Zhorov A, Lin J, Scher J, Kumari S, Blair D, Hippen KL, Blazar BR, Abramson SB, Lafaille JJ, Dustin ML> ;Proc. Natl. Acad. Sci. U.S.A.. 2012-01-31
• Natural product-guided discovery of a fungal chitinase inhibitor.
  Rush, C.L., Schüttelkopf, A.W., Hurtado-Guerrero, R., Blair, D.E., Ibrahim, A.M., Desvergnes, S., Eggleston, I.M., van Aalten, D.F.> ;Chem Biol. 2010 Dec 22
• Chemotaxis signaling protein CheY binds to the rotor protein FliN to control the direction of flagellar rotation in Escherichia coli.
  Sarkar MK, Paul K, Blair D> ;Proc. Natl. Acad. Sci. U.S.A.. 2010-05-18
• Structure and mechanism of chitin deacetylase from the fungal pathogen Colletotrichum lindemuthianum.
  Blair, D.E., Hekmat, O., Schüttelkopf, A.W., Shrestha, B., Tokuyasu, K., Withers, S.G., van Aalten, D.F.> ;Biochemistry. 2006 Aug 8
• Structure and metal-dependent mechanism of peptidoglycan deacetylase, a streptococcal virulence factor.
  Blair, D. E., Schüttelkopf, A. W., MacRae, J. I., van Aalten, D. M.> ;Proc Natl Acad Sci U S A. 2005 Oct 25
• Acetazolamide-based fungal chitinase inhibitors.
  Schüttelkopf, A. W., Gros, L., Blair, D. E., Frearson, J. A., van Aalten, D. M., Gilbert, I. H.> ;Bioorg Med Chem. 2010 Dec 1
• Substrate and product analogues as human O-GlcNAc transferase inhibitors.
  Dorfmueller, H. C., Borodkin, V. S., Blair, D. E., Pathak, S., Navratilova, I., van Aalten, D. M.> ;Amino Acids. 2011 Mar
• Structures of Bacillus subtilis PdaA, a family 4 carbohydrate esterase, and a complex with N-acetyl-glucosamine.
  Blair, D. E., van Aalten, D. M.> ;FEBS Lett. 2004 Jul 16
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