DavidBrownsteinMD

PubMed

• 116 citations
  Glucocorticoid receptor is required for foetal heart maturation
  Eva A. Rog-Zielinska, Adrian Thomson, Christopher J. Kenyon, David G. Brownstein, Carmel M. Moran, Dorota Szumska, Zoi Michailidou, Jennifer Richardson, Elizabeth Owen...> ;Human Molecular Genetics. 2013 Aug 15
• 70 citations
  11β-Hydroxysteroid Dehydrogenase Type 1, But Not Type 2, Deficiency Worsens Acute Inflammation and Experimental Arthritis in Mice
  Agnes E. Coutinho, Mohini Gray, David G. Brownstein, Donald Salter, Deborah A. Sawatzky, Spike Clay, James S. Gilmour, Jonathan R. Seckl, John Savill, Karen E. Chapman> ;Endocrinology. 2012 Jan 1
• 97 citations
  Acute Multiple Organ Failure in Adult Mice Deleted for the Developmental Regulator Wt1
  You-Ying Chau, David Brownstein, Heidi K. Mjoseng, Wen-Chin Lee, Natalija Buza-Vidas, Claus Nerlov, Sten Eirik W. Jacobsen, Paul Perry, Rachel L. Berry, Anna Thornburn...> ;Plos Genetics. 2011 Dec 22
• 114 citations
  A Wt1-controlled chromatin switching mechanism underpins tissue-specific Wnt4 activation and repression
  Abdelkader Essafi, Anna Webb, Rachel L. Berry, Joan Slight, Sally F. Burn, Lee Spraggon, Victor Velecela, Ofelia M. Martínez-Estrada, John H. Wiltshire, Stefan G. E. R...> ;Developmental Cell. 2011 Sep 13
• 29 citations
  Smooth muscle cell-specific knockout of androgen receptor: a new model for prostatic disease
  Michelle Welsh, Lindsey Moffat, Alan S. McNeilly, David G. Brownstein, Philippa T. K. Saunders, Richard M. Sharpe, Lee B. Smith> ;Endocrinology. 2011 Jul 5
• 35 citations
  Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet.
  Pauline Jamieson, Mark E. Cleasby, Yael Kuperman, Nicholas M. Morton, Paul A.T. Kelly, David G. Brownstein, K. J. Mustard, Joan Vaughan, Richard Carter, Caroline Hahn,...> ;Diabetologia. 2011 Jun 11
• 4 citations
  Expression of urocortin peptides in canine myocardium and plasma
  Gemma Fraga Veloso, Dan G. Ohad, A. J. Francis, Joan Vaughan, David Brownstein, Geoffrey Culshaw, Wylie Vale, Anne French, Pauline Jamieson> ;Veterinary Journal. 2011 Jun 1
• 68 citations
  11β-Hydroxysteroid Dehydrogenase Type 2 Deficiency Accelerates Atherogenesis and Causes Proinflammatory Changes in the Endothelium in Apoe−/− Mice
  Graeme A. Deuchar, Danielle McLean, Patrick W. F. Hadoke, David G. Brownstein, David J. Webb, John J. Mullins, Karen E. Chapman, Jonathan R. Seckl, Yuri Kotelevtsev> ;Endocrinology. 2011 Apr 9
• 46 citations
  Haploinsufficiency of the murine Col3a1 locus causes aortic dissection: a novel model of the vascular type of Ehlers–Danlos syndrome
  Lee B. Smith, Patrick W. F. Hadoke, Emma Dyer, Martin A. Denvir, David G. Brownstein, Eileen Miller, Nancy Nelson, Sara Wells, Michael Cheeseman, Andy Greenfield> ;Cardiovascular Research. 2011 Apr 1
• 27 citations
  Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla
  Rachel L. Berry, Louise Harewood, Liming Pei, Malcolm E. Fisher, David G. Brownstein, Allyson Ross, William A. Alaynick, Julie Moss, Nicholas D. Hastie, Peter Hohenste...> ;Human Molecular Genetics. 2011 Mar 1
• 28 citations
  Persistence of functional hepatocyte-like cells in immune-compromised mice
  Catherine Payne, Kay Samuel, A. Pryde, Jason King, David G. Brownstein, Joerg Schrader, Claire N. Medine, Stuart J. Forbes, John P. Iredale, Philip N. Newsome, David C...> ;Liver International. 2011 Feb 1
• 24 citations
  Deletion of androgen receptor in the smooth muscle of the seminal vesicles impairs secretory function and alters its responsiveness to exogenous testosterone and estra...
  Michelle Welsh, Lindsey Moffat, Laura Jack, Alan S. McNeilly, David G. Brownstein, Philippa T. K. Saunders, Richard M. Sharpe, Lee B. Smith> ;Endocrinology. 2010 Jul 1
• 13 citations
  Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease
  Jim Selfridge, Liang Song, David G. Brownstein, David W. Melton> ;DNA Repair. 2010 Jun 4
• 52 citations
  Col4a1 mutation in mice causes defects in vascular function and low blood pressure associated with reduced red blood cell volume
  Tom Van Agtmael, Matthew A. Bailey, Ursula Schlötzer-Schrehardt, Eilidh Craigie, Ian J. Jackson, David G. Brownstein, Ian L. Megson, John J. Mullins> ;Human Molecular Genetics. 2010 Mar 15
• 3 citations
  Expression of the neuroprotective slow Wallerian degeneration (WldS) gene in non-neuronal tissues.
  Thomas M. Wishart, David G. Brownstein, Derek Thomson, Anca M Tabakova, Katherine M. Boothe, Jack W. Tsao, Thomas H. Gillingwater> ;BMC Neuroscience. 2009 Dec 16
• 24 citations
  eEF1A2 and neuronal degeneration
  Catherine M. Abbott, Helen J Newbery, Charlotte E. Squires, David G. Brownstein, Lowri A Griffiths, Dinesh C. Soares> ;Biochemical Society Transactions. 2009 Dec 1
• 7 citations
  Topical thymidine dinucleotide application protects against UVB-induced skin cancer in mice with DNA repair gene (Ercc1)-deficient skin.
  Nicola J. Lawrence, Liang Song, Jennifer Doig, Ann-Marie Ritchie, David G. Brownstein, David W. Melton> ;DNA Repair. 2009 May 1
• 27 citations
  Real-time visualization of human prolactin alternate promoter usage in vivo using a double-transgenic rat model.
  Sabrina Semprini, Sönke Friedrichsen, Claire V. Harper, J R McNeilly, Antony Adamson, David G. Spiller, Nina Kotelevtseva, Gillian Brooker, David G. Brownstein, Alan S...> ;Molecular Endocrinology. 2009 Apr 1
• 31 citations
  Cyp11b1 null mouse, a model of congenital adrenal hyperplasia.
  Linda J. Mullins, Audrey Peter, Nicola Wrobel, J R McNeilly, Alan S. McNeilly, Emad A S Al-Dujaili, David G. Brownstein, John J. Mullins, Christopher J. Kenyon> ;The Journal of Biological Chemistry. 2009 Feb 6
• 40 citations
  Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet
  Zoi Michailidou, Rod Carter, E Marshall, Heidi G. Sutherland, David Brownstein, E. Owen, K. Cockett, Valerie Kelly, Lynne Ramage, Emad A S Al-Dujaili, M. Ross, Ioanna ...> ;FASEB Journal. 2008 Nov 1
• 6 citations
  Effects on kidney disease, fertility and development in mice inheriting a protein-truncating Denys-Drash syndrome allele (Wt1tmT396)
  Charles E. Patek, David G. Brownstein, Stewart Fleming, Caroline Wroe, Lorraine Rose, Anna Webb, Rachel L. Berry, Paul S. Devenney, Marion F Walker, Oliver D. K. Maddo...> ;Transgenic Research. 2008 Jun 1
• 25 citations
  Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis.
  Charles E. Patek, Mark J. Arends, William A Wallace, Feijun Luo, Suzanne Hagan, David G. Brownstein, Lorraine Rose, Paul S. Devenney, Marion F Walker, Sarah J. Plowman...> ;Experimental Cell Research. 2008 Mar 10
• 24 citations
  A neurological phenotype in mice with DNA repair gene Ercc1 deficiency.
  Nicola J. Lawrence, Joseph J. Sacco, David G. Brownstein, Thomas H. Gillingwater, David W. Melton> ;DNA Repair. 2008 Feb 1
• 30 citations
  A missense mutation in the murine Opa3 gene models human Costeff syndrome.
  Vanessa J. Davies, Kathryn Ann Powell, Kathryn E. White, Wan Fen Yip, Vanessa Hogan, Andrew John Hollins, Jennifer Rhian Davies, Malgorzata Piechota, David G. Brownste...> ;Brain. 2008 Feb 1
• 41 citations
  A Switch in the Mechanism of Hypertension in the Syndrome of Apparent Mineralocorticoid Excess
  Matthew A. Bailey, Janice M. Paterson, Patrick W. F. Hadoke, Nicola Wrobel, Christopher Bellamy, David G. Brownstein, Jonathan R. Seckl, John J. Mullins> ;Journal of the American Society of Nephrology. 2008 Jan 1
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Lectures

• 11th Annual International Restorative Medicine Conference 
  Association for the Advancement of Restorative Medicine (AARM), San Diego, California - 10/3/2013
• 11th Annual International Restorative Medicine Conference 
  Association for the Advancement of Restorative Medicine (AARM), San Diego, California - 10/3/2013
• 13th Clinical Applications for Age Management Medicine 
  Age Management Medicine Group(AMMG), Las Vegas, Nevada - 11/1/2012