DavidCachiaMD

PubMed

• 18 citations
  Alliance A071401: Phase II Trial of Focal Adhesion Kinase Inhibition in Meningiomas With SomaticMutations.
  Priscilla K Brastianos, Erin L Twohy, Elizabeth R Gerstner, Timothy J Kaufmann, A John Iafrate, Jochen Lennerz, Suriya Jeyapalan, David E Piccioni, Varun Monga, Camilo...> ;Journal of Clinical Oncology. 2023 Jan 20
• Current Use and Limitations of Cultured High-Grade Meningioma Cells in Neuro-Oncological Research - In Response to: "Caution Using Meningioma Cell Lines as Tumor Models".
  Jaime L Martinez Santos, Paola Suarez-Meade, David Cachia, Scott Lindhorst, Arabinda Das> ;Cancer Investigation. 2021 Oct 19
• Analysis of the P53N a Novel Protein Encoded on Chromosome 22q12.1-12.3 in Glioblastomas and Ependymomas Specimens.
  Bruce M. Frankel, David Cachia, Sunil J. Patel, Arabinda Das> ;Journal of Molecular Neuroscience. 2021 Feb 17
• 2 citations
  Strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression.
  Mohammed Alshareef, Gibson Klapthor, Stephen Lowe, Jessica Barley, David Cachia, Bruce M. Frankel> ;Surgical Neurology International. 2020 Dec 22
• 69 citations
  Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Gli...
  Timothy F. Cloughesy, Kevin Petrecca, Tobias Walbert, Nicholas Butowski, Michael Salacz, James Perry, Denise Damek, Daniela A. Bota, Chetan Bettegowda, Jay-Jiguang Zhu...> ;JAMA Oncology. 2020 Dec 1
• 5 citations
  Preconditioning with INC280 and LDK378 drugs sensitizes MGMT-unmethylated glioblastoma to temozolomide: Pre-clinical assessment
  Arabinda Das, Mohammed Alshareef, Guilherme B. F. Porto, Libby Kosnik Infinger, William A. Vandergrift, Scott Lindhorst, Abhay K. Varma, Sunil J. Patel, David Cachia> ;Journal of the Neurological Sciences. 2020 Aug 21
• 9 citations
  MGMT-inhibitor in combination with TGF-βRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells
  Arabinda Das, Fraser Henderson, Mohammed Alshareef, Guilherme B. F. Porto, Indira Kanginakudru, Libby Kosnik Infinger, William Alexander Vandergrift, Scott Lindhorst, ...> ;Clinical & Translational Oncology. 2021 Mar 1
• 16 citations
  Ganoderic acid A/DM-induced NDRG2 over-expression suppresses high-grade meningioma growth
  Arabinda Das, Mohammed Alshareef, Fraser Henderson, J. L. Martinez Santos, William Alexander Vandergrift, Scott Lindhorst, Abhay K. Varma, Libby Kosnik Infinger, Sunil...> ;Clinical & Translational Oncology. 2020 Jul 1
• 11 citations
  In Vitro Effect of Dovitinib (TKI258), a Multi-Target Angiokinase Inhibitor on Aggressive Meningioma Cells
  Arabinda Das, Jaime L Martinez Santos, Mohammed Alshareef, Guilherme B. F. Porto, Libby Kosnik Infinger, William A. Vandergrift, Scott Lindhorst, Abhay K. Varma, Sunil...> ;Cancer Investigation. 2020 Jun 8
• 5 citations
  Targeting Subventricular Zone Progenitor Cells with Intraventricular Liposomal Encapsulated Cytarabine in Patients with Secondary Glioblastoma : A Report of Two Cases.
  Bruce M. Frankel, David Cachia, Sunil J. Patel, Arabinda Das> ;SN Comprehensive Clinical Medicine. 2020 May 23
• 9 citations
  Pineal parenchymal tumor of intermediate differentiation: a single-institution experience.
  Joo Yeon Nam, Andrea R. Gilbert, David Cachia, Jacob Mandel, Gregory N. Fuller, Marta Penas-Prado, John de Groot, Carlos Kamiya-Matsuoka> ;Neuro-Oncology Practice. 2020 May 12
• Analysis of P78: A Novel Cytoplasmic Membrane-Associated Protein Encoded on Chromosome 19q13.3 in Glioma Specimens.
  Bruce M. Frankel, David Cachia, Sunil J. Patel, Arabinda Das> ;Journal of Molecular Neuroscience. 2020 May 4
• 14 citations
  Evaluating anti-tumor activity of palbociclib plus radiation in anaplastic and radiation-induced meningiomas: pre-clinical investigations
  Arabinda Das, Mohammed Alshareef, J. L. Martinez Santos, Guilherme B. F. Porto, Daniel G. McDonald, Libby Kosnik Infinger, William Alexander Vandergrift, Scott Lindhor...> ;Clinical & Translational Oncology. 2020 Apr 6
• 11 citations
  Seizures in Patients With Metastatic Brain Tumors: Prevalence, Clinical Characteristics, and Features on EEG.
  Shaun Ajinkya, Jonah Fox, Peter Houston, Adam Greenblatt, Alain Lekoubou, Scott Lindhorst, David Cachia, Adriana Olar, Ekrem Kutluay> ;Journal of Clinical Neurophysiology. 2019 Dec 17
• Clinical characteristics, EEG findings and implications of status epilepticus in patients with brain metastases.
  Jonah Fox, Shaun Ajinkya, Adam Greenblatt, Peter Houston, Alain Lekoubou, Scott Lindhorst, David Cachia, Adriana Olar, Ekrem Kutluay> ;Journal of the Neurological Sciences. 2019 Dec 15
• 8 citations
  Seizures in patents with primary central nervous system lymphoma: Prevalence and associated features
  Jonah Fox, Shaun Ajinkya, Peter Houston, Scott Lindhorst, David Cachia, Adriana Olar, Ekrem Kutluay> ;Journal of the Neurological Sciences. 2019 May 15
• 13 citations
  Clinical trial participation of patients with glioblastoma at The University of Texas MD Anderson Cancer Center.
  Rebecca Harrison, Mark Anderson, David Cachia, Carlos Kamiya-Matsuoka, Shiao Pei Weathers, Barbara O’Brien, Marta Penas-Prado, W. K. Alfred Yung, Jimin Wu, Ying Yuan, ...> ;European Journal of Cancer. 2019 May 1
• 122 citations
  The molecular landscape of glioma in patients with Neurofibromatosis 1.
  Fulvio D'Angelo, Michele Ceccarelli, Tala, Luciano Garofano, Jing Zhang, Veronique Frattini, Francesca Pia Caruso, Genevieve Lewis, Kristin Alfaro, Luc Bauchet, Giulia...> ;Nature Medicine. 2019 Jan 1
• 12 citations
  Oncolytic myxoma virus synergizes with standard of care for treatment of glioblastoma multiforme
  Chase Burton, Arabinda Das, Daniel G. McDonald, William A. Vandergrift, Sunil J. Patel, David Cachia, Eric Bartee> ;Oncolytic Virotherapy. 2018 Nov 19
• 13 citations
  Single agent efficacy of the HDAC inhibitor DATS in preclinical models of glioblastoma.
  Arabinda Das, Fraser Henderson, Stephen Lowe, Gerald C. Wallace, William A. Vandergrift, Scott Lindhorst, Abhay K. Varma, Libby Kosnik Infinger, Pierre Giglio, Narendr...> ;Cancer Chemotherapy and Pharmacology. 2018 Sep 12
• 6 citations
  Case-based review: ependymomas in adults.
  David Cachia, Derek R. Johnson, Timothy J. Kaufmann, Stephen Lowe, Samuel Andersen, Adriana Olar, Samuel Lewis Cooper, Bruce M. Frankel, Mark R. Gilbert> ;Neuro-Oncology Practice. 2018 Aug 3
• 45 citations
  Inability of positive phase II clinical trials of investigational treatments to subsequently predict positive phase III clinical trials in glioblastoma
  Jacob Mandel, Shlomit Yust-Katz, Akash J. Patel, David Cachia, Diane Liu, Minjeong Park, Ying Yuan, Thomas A. Kent, John de Groot> ;Neuro-Oncology. 2018 Jan 10
• 18 citations
  Ependymomas arising outside of the central nervous system: A case series and literature review.
  Shlomit Yust Katz, David Cachia, Carlos Kamiya-Matsuoka, Adriana Olar, Brett Theeler, Marta Penas Prado, Mark R. Gilbert, Terri Armstrong> ;Journal of Clinical Neuroscience. 2018 Jan 1
• Corrigendum to 'Ependymomas arising outside of the central nervous system: A case series and literature review' [J Clin Neurosci 47 (2018) 202-207].
  Shlomit Yust Katz, David Cachia, Carlos Kamiya-Matsuoka, Adriana Olar, Brett Theeler, Marta Penas Prado, Mark R. Gilbert, Terri Armstrong> ;Journal of Clinical Neuroscience. 2017 Dec 1
• 13 citations
  Radiographic patterns of progression with associated outcomes after bevacizumab therapy in glioblastoma patients.
  David Cachia, Nabil Elshafeey, Carlos Kamiya-Matsuoka, Masumeh Hatami, Kristin Alfaro-Munoz, Jacob Mandel, Rivkah Colen, John DeGroot> ;Journal of Neuro-Oncology. 2017 Oct 1
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Journal Articles

• Inability of positive phase II clinical trials of investigational treatments to subsequently predict positive phase III clinical trials in glioblastoma  
  Mandel JJ, Yust-Katz S, Patel A, Cachia D, Liu D, Park M, Yuan Y, Kent K, de Groot JF, Neuro Oncol, 1/10/2018
• Dorsal Column Myelopathy after Intrathecal Chemotherapy for Leukemia  
  Pinnix CC, Chi L, Jabbour EJ, Milgrom SA, Smith GL, Daver N, Garg N, Cykowski MD, Fuller G, Cachia D, Kamiya C, Woodman K, Dinardo C, Jain N, Kadia TM, Pemmaraju N, Oh..., Am J Hematol, 1/1/2017
• Radiographic patterns of progression with associated outcomes after bevacizumab therapy in glioblastoma patients  
  Cachia D, Elshafeey NA, Kamiya-Matsuoka C, Hatami M, Alfaro-Munoz KD, Mandel JJ, Colen R, DeGroot JF, J Neurooncol, 1/1/2017
• Interventions for the management of fatigue in adults with a primary brain tumour  
  Day J, Yust-Katz S, Cachia D, Wefel J, Katz LH, Tremont I, Bulbeck H, Armstrong T, Rooney AG, Cochrane Database Syst Rev, 1/13/2016
• Severe peripheral neuropathy following carfilzomib, rituximab, and dexamethasone for initial treatment of Waldenstrom's macroglobulinemia  
  Alfaraj WA, Cachia D, Tummala S, Thomas SK, Manasanch EE, Ann Hematol, 1/1/2016
• Impact of IDH-1 mutation status on outcome in clinical trials for recurrent glioblastoma  
  Mandel JJ, Cachia D, Liu D, Wilson C, Aldape K, Fuller G, de Groot JF, J Neurooncol, 1/1/2016
• Rip1 and Rip3 complex regulates radiation-induced programmed necrosis in glioblastoma  
  Das A , McDonald D, Dixon-Mah YN, Jacqmin DJ, Vandergrift III WA, Lindhorst SM, Cachia D, Varma AK, Vanek K, Banik NL, Jenrette III JM, Raizer JJ, Giglio P, Patel SJ, Tumour Biol, 1/18/2015
• Middle cerebral artery territory infarct due to Cryptococcus infection: An uncommon indication for CSF analysis in stroke patients  
  Cachia D, Singh C, Tetzlaff M, Penas Prado M, Diagn Cytopathol, 1/4/2015
• C11orf95-RELA fusion present in a primary supratentorial ependymoma and recurrent sarcoma  
  Cachia D, Wani K, Penas-Prado M, Olar A, McCutcheon IE, Benjamin RS, Armstrong TS, Gilbert MR, Aldape KD, Brain Tumor Pathol, 1/1/2015
• Myelopathy following intrathecal chemotherapy in adults: a single institution experience  
  Cachia D, Kamiya-Matsuoka C, Pinnix CC, Chi L, Kantarjan HM, Cortes JE, Daver N, Woodman K, J Neurooncol, 1/1/2015
• Cough and confusion in an elderly gentleman with chronic lymphocytic leukemia  
  Cachia D, Makhija M, Smith T, J Clin Neurosci, 1/1/2015
• Ischemic stroke in patients with gliomas at The University of Texas-MD Anderson Cancer Center  
  Cachia D, Kamiya-Matsuoka C, Yust-Katz S, Rodriguez YA, Garciarena P, Rodarte EM, Tremont-Lukats IW, J Neurooncol, 1/1/2015
• Primary and Secondary Gliosarcomas: clinical, molecular and survival characteristics  
  Cachia D, Kamiya-Matsuoka C, Mandel JJ, Olar A, Cykowski MD, Armstrong TS, Fuller GN, Gilbert MR, De Groot JF, J Neurooncol, 1/1/2015
• Synergistic effects of crizotinib and temozolomide in experimental FIG-ROS1 fusion-positive glioblastoma  
  Das A, Cheng RR, Hilbert MLT, Dixon-Moh YN, Decandio M, Vandergrift WA, Banik NL, Lindhorst SM, Cachia D, Varma AK, Patel SJ, Giglio P, Cancer Growth Metastasis, 1/1/2015
• Synchronous rosette forming glioneuronal tumor and diffuse astrocytoma with molecular characterization: a case report  
  Cachia D, Penas Prado M, Theeler B, Hamilton J, McCutcheon I, Fuller GN, Clin Neuropathol, 1/1/2014
• Primary Brain Tumors and Posterior Reversible Encephalopathy Syndrome  
  Cachia D, Kamiya-Matsuoka C, Olar A, Armstrong TS, Gilbert MR, Neuro Oncol Pract, 1/1/2014
• Leptomeningeal dissemination in glioblastoma; An inspection of risk factors, treatment, and outcomes at a single institution  
  Mandel JJ, Yust-Katz S, Cachia D, Wu J, Liu D, de Groot JF, Yung AWK, Gilbert MR, J Neurooncol, 1/1/2014
• A rare presentation of hypertrophic olivary degeneration secondary to primary CNS lymphoma  
  Cachia D, Izzy S, Smith T, Ionete C, JAMA Neurol, 1/1/2013
• Cognitive delay in a 7-year-old girl  
  Cachia D, Stine C, Neurology, 1/1/2013
• L5 radiculopathy causing absent superficial peroneal sensory response  
  Cachia D, Salameh J, Neurological Bulletin, 1/1/2013
• Widely metastatic meningioma  
  Cachia D, Alderson L, Smith T, Yunus S, Arch Neurol, 1/1/2012
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Books/Book Chapters

• 5 Minute Clinical Consult 
  Chapter: Cluster Headache 
  Cachia D, Mitchell A, Fontneau N2012
• Merritt's Neurology 
  Chapter: Spinal Tumors 
  Cachia D, Tatsui C, Gilbert MREdition 13th,
• Ependymomas: Prognostic Factors, Treatment Strategies and Clinical Outcomes 
  Chapter: Prognosis and outcomes in ependymal tumors. 
  Metrus NR, Cachia D
• NeuroICU Comprehensive Board Review 
  Chapter: Neuro-oncology section. 
  Santos Pinheiro F, Cachia DEdition 1st,
• Top 10 Contributions on Neurology 
  Chapter: Molecular Markers in Gliomas and their Impact in Clinical Practice 
  Henderson Jr. F, Cachia D, Varma A
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Abstracts/Posters

• Multi Cranial Neuropathy Secondary To Primary Glioblastoma Of Trigeminal Nerve: Case Report.
  Cachia D, American Academy of Neurology, Los Angeles, CA, 1/1/2018
• Galectin-1 upregulates CXCR4 in glioblastoma through upregulation of CXCR4 via NF-KappaB activation.
  Cachia D, American Association for Cancer Research, 1/1/2018
• C18-Ceramide Analogue Drug Overcomes Resistance to Temozolomide in Gliobastoma.
  Cachia D, Society of Neuro-Oncology Meeting, New Orleans, LA, 1/1/2018
• Overcoming Radiation Resistance in Meningioma: The Emerging Role of CDK4/6 Inhibitor.
  Cachia D, Society of Neuro-Oncology Meeting, New Orleans, LA, 1/1/2018
• Galectins in Glioblastoma: Opportunities for combined Therapy.
  Cachia D, American Association for Cancer Research, 1/1/2017
• Targeting CCR2 Signaling in Pediatric Medulloblastoma.
  Cachia D, Society of Neuro-Oncology Meeting, San Francisco, CA, 1/1/2017
• Investigating the expression of antigen processing molecules in Brain Metastases of Triple-negative breast cancers.
  Cachia D, Society of Neuro-Oncology Meeting, San Francisco, CA, 1/1/2017
• Unlocking the Promise of Myxoma Virus Therapy- Combination of Radiation plus Crizotinib or Bevacizumab to Enhance Efficacy in Glioblastoma.
  Cachia D, Society of Neuro-Oncology Meeting, San Francisco, CA, 1/1/2017
• Radiation induced late malignant meningioma transformation: CDK 4/6 Inhibitor therapy.
  Cachia D, Society of Neuro-Oncology Meeting, San Francisco, CA, 1/1/2017
• Relationship between coping style and psychological distress among individuals diagnosed with primary brain tumors.
  Cachia D, American Psychooncology Society, 1/1/2016
• Impact of IDH-1 Mutation Status on Outcome in Clinical Trials for Recurrent Glioblastoma.
  Cachia D, American Academy of Neurology, 1/1/2016
• American Academy of Neurology?
  Cachia D, American Academy of Neurology, 1/1/2016
• Dovitinib (TKI258), a Multi-target Angiokinase inhibitor, is Effective Regardless of NF Mutation Status in Meningioma.
  Cachia D, Society for Neuro-Oncology Conference on Meningioma, 1/1/2016
• Diffusion kurtosis imaging of the subventricular zone in glioblastoma.
  Cachia D, Society of Neuro-Oncology Meeting, Scottsdale, AZ, 1/1/2016
• Preclinical testing of dietary histone deacetylase inhibitors on fresh FIG-ROS1 positive human glioblastoma tissue in ex-vivo models.
  Cachia D, Society of Neuro-Oncology Meeting, Scottsdale, AZ, 1/1/2016
• Combination therapy of LDK378 and INC280 (INCB028060) enhances temozolomide sensitivity in MGMT unmethylated glioblastoma: pre clinical assessment.
  Cachia D, Society of Neuro-Oncology Meeting, Scottsdale, AZ, 1/1/2016
• Improving gemcitibine-mediated radio-sensitization using molecularly targeted meningioma therapy.
  Cachia D, Society of Neuro-Oncology Meeting, Scottsdale, AZ, 1/1/2016
• Ependymomas arising outside of the central nervous system: a case series.
  Cachia D, Society of Neuro-Oncology Meeting, Scottsdale, AZ, 1/1/2016
• IDH1 mutation status and outcome in clinical trials for recurrent glioblastoma.
  Cachia D, American Society of Oncology Annual Meeting, 1/1/2015
• Radiographic patterns of progression with associated outcomes after bevacizumab therapy in glioblastoma patients.
  Cachia D, Society of Neuro-Oncology Meeting, San Antonio, 1/1/2015
• Myelopathy following intrathecal chemotherapy: a case series in adults.
  Cachia D, Society of Neuro-Oncology Meeting, Miami, FL, 1/1/2014
• Temozolomide-based therapy for the management of progressive pituitary carcinoma.
  Cachia D, Society of Neuro-Oncology Meeting, Miami, FL, 1/1/2014
• Primary Brain Tumors and Posterior Reversible Encephalopathy Syndrome
  Cachia D, Society of Neuro-Oncology Meeting, Miami, FL, 1/1/2014
• 59 year old gentleman with multiple extracranial metastases from anaplastic meningioma.
  Cachia D, American Academy of Neurology (AAN), San Diego, CA, 1/1/2013
• Peripheral Neuropathy Following Hair Dye Exposure: A Case Report.
  Cachia D, American Academy of Neurology (AAN), San Diego, CA, 1/1/2013
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Lectures

• Treatment of Diffuse Gliomas in Adults: What's New? 
  1/1/2018
• Anti-Tumor Activity of CDK 4/6 Inhibitor Palbociclib in Rb+ Meningioma: Pre-clinical Assessment. 
  1/1/2016
• RIP3 is a Critical Regulator of Radiation Induced Programmed Necrosis and Inflammation in a Preclinical Model of Glioblastoma. 
  1/1/2016
• Interventions for fatigue in people with gliomas. 
  Scottsdale, AZ - 1/1/2016
• Molecular classification of diffuse gliomas; Ready for prime time? 
  University of Massachusetts - 1/1/2014
• Another Neuropathy... 
  University of Massachusetts - 1/1/2013
• Meningioma: A benign brain tumor? 
  University of Massachusetts - 1/1/2012
• Case Presentation: Brachial Amyotrophic Diplegia 
  University of Massachusetts - 1/1/2011
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