DavidAllenChappellMD

PubMed

• 74 citations
  Macrophage-Specific Expression of Human Lipoprotein Lipase Accelerates Atherosclerosis in Transgenic Apolipoprotein E Knockout Mice but Not in C57BL/6 Mice
  Katina M. Wilson, Glenna L. Fry, David A. Chappell, Curt D. Sigmund, Jheem D. Medh> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2001 Nov 1
• 3 citations
  Calcium-activated potassium channels mask vascular dysfunction associated with oxidized LDL exposure in rabbit aorta.
  Jennifer M Bocker, Francis J. Miller, Christine L. Oltman, David A. Chappell, David D. Gutterman> ;Japanese Heart Journal. 2001 May 1
• 26 citations
  Lipoprotein lipase- and hepatic triglyceride lipase-promoted very low density lipoprotein degradation proceeds via an apolipoprotein E-dependent mechanism
  Jheem D. Medh, Glenna L. Fry, Susan L. Bowen, Stacie Ruben, Howard Wong, David A. Chappell> ;Journal of Lipid Research. 2000 Nov 1
• 13 citations
  Hepatic triglyceride lipase promotes low density lipoprotein receptor-mediated catabolism of very low density lipoproteins in vitro.
  Jheem D. Medh, Susan L. Bowen, Glenna L. Fry, Stacie Ruben, John S. Hill, Howard Wong, David A. Chappell> ;Journal of Lipid Research. 1999 Jul 1
• 42 citations
  Agonist-specific impairment of coronary vascular function in genetically altered, hyperlipidemic mice
  Kathryn G. Lamping, Daniel W. Nuno, David A. Chappell, Frank M. Faraci> ;The American Journal of Physiology. 1999 Apr 1
• 4 citations
  Phenotypic consequences of a deletion of exons 2 and 3 of the LDL receptor gene
  Olaug K. Rødningen, Serena Tonstad, Jheem D. Medh, David A. Chappell, Leiv Ose, Trond P. Leren> ;Journal of Lipid Research. 1999 Feb 1
• 50 citations
  Receptor-mediated mechanisms of lipoprotein remnant catabolism.
  David A. Chappell, Jheem D. Medh> ;Progress in Lipid Research. 1998 Dec 1
• 75 citations
  Overexpression of Human Superoxide Dismutase Inhibits Oxidation of Low-Density Lipoprotein by Endothelial Cells
  Xiang Fang, Neal L. Weintraub, C. David Rios, David A. Chappell, Ralf M. Zwacka, John F. Engelhardt, Larry W. Oberley, Tao Yan, Donald D. Heistad, Arthur A. Spector> ;Circulation Research. 1998 Jun 29
• 140 citations
  Atherosclerosis, Vascular Remodeling, and Impairment of Endothelium-Dependent Relaxation in Genetically Altered Hyperlipidemic Mice
  Srinivas Bonthu, Donald D. Heistad, David A. Chappell, Kathryn G. Lamping, Frank M. Faraci> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 1997 Nov 1
• 68 citations
  Lipoprotein Lipase Binds to Low Density Lipoprotein Receptors and Induces Receptor-mediated Catabolism of Very Low Density Lipoproteins in Vitro
  Jheem D. Medh, Susan L. Bowen, Glenna L. Fry, Stacie Ruben, Mark E. Andracki, Ituro Inoue, Jean-Marc Lalouel, Dudley K. Strickland, David A. Chappell> ;The Journal of Biological Chemistry. 1996 Jul 19
• 129 citations
  The Very Low Density Lipoprotein Receptor Mediates the Cellular Catabolism of Lipoprotein Lipase and Urokinase-Plasminogen Activator Inhibitor Type I Complexes
  Kelley M. Argraves, Frances D. Battey, Colin D. MacCalman, Keith R. McCrae, Mats Gåfvels, Karen Kozarsky, David A. Chappell, Jerome F. Strauss, Dudley K. Strickland> ;The Journal of Biological Chemistry. 1995 Nov 3
• 85 citations
  Glycoprotein 330/low density lipoprotein receptor-related protein-2 mediates endocytosis of low density lipoproteins via interaction with apolipoprotein B100.
  Steingrimur Stefansson, David A. Chappell, Kelley M. Argraves, Dudley K. Strickland, W. Scott Argraves> ;The Journal of Biological Chemistry. 1995 Aug 18
• 61 citations
  gp330 on type II pneumocytes mediates endocytosis leading to degradation of pro-urokinase, plasminogen activator inhibitor-1 and urokinase-plasminogen activator inhibi...
  Steingrimur Stefansson, M Z Kounnas, Jack Henkin, R.K. Mallampalli, D.A. Chappell, Dudley K. Strickland, William Scott Argraves> ;Journal of Cell Science. 1995 Jun 1
• 102 citations
  The cellular internalization and degradation of hepatic lipase is mediated by low density lipoprotein receptor-related protein and requires cell surface proteoglycans.
  M Z Kounnas, David A. Chappell, Howard Wong, W. Scott Argraves, Dudley K. Strickland> ;The Journal of Biological Chemistry. 1995 Apr 21
• 107 citations
  The 39-kDa Receptor-associated Protein Modulates Lipoprotein Catabolism by Binding to LDL Receptors
  Jheem D. Medh, Glenna L. Fry, Susan L. Bowen, Marc W. Pladet, Dudley K. Strickland, David A. Chappell> ;The Journal of Biological Chemistry. 1995 Jan 13
• 159 citations
  The 39-kDa receptor-associated protein regulates ligand binding by the very low density lipoprotein receptor.
  Frances D. Battey, M.E. Gåfvels, Desmond J. Fitzgerald, William Scott Argraves, D.A. Chappell, J.F. Strauss rd, Dudley K. Strickland> ;The Journal of Biological Chemistry. 1994 Sep 16
• 9 citations
  The Carboxy‐Terminal Domain of Lipoprotein Lipase Induces Cellular Catabolism of Normal Very Low Density Lipoproteins via the Low Density Lipoprotein Receptor—Related ...
  David A. Chappell, Ituro Inoue, Glenna L. Fry, Marc W. Pladet, Per-Henrik Iverius, Jean-Marc Lalouel, Dudley K. Strickland> ;Annals of the New York Academy of Sciences. 1994 Sep 1
• 49 citations
  Cellular catabolism of normal very low density lipoproteins via the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is induced by the C...
  David A. Chappell, I Inoue, Glenna L. Fry, Marc W. Pladet, Susan L. Bowen, P H Iverius, J M Lalouel, D K Strickland> ;The Journal of Biological Chemistry. 1994 Jul 8
• 95 citations
  The carboxyl-terminal domain of lipoprotein lipase binds to the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor (LRP) and mediates bind...
  Suzanne E. Williams, I Inoue, Huan Tran, G L Fry, M W Pladet, P H Iverius, J M Lalouel, D.A. Chappell, Dudley K. Strickland> ;The Journal of Biological Chemistry. 1994 Mar 25
• 40 citations
  Low density lipoprotein receptors bind and mediate cellular catabolism of normal very low density lipoproteins in vitro.
  David A. Chappell, Glenna L. Fry, M A Waknitz, L E Muhonen, Marc W. Pladet> ;The Journal of Biological Chemistry. 1993 Dec 5
• 160 citations
  Lipoprotein lipase induces catabolism of normal triglyceride-rich lipoproteins via the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor ...
  David A. Chappell, Glenna L. Fry, M A Waknitz, L E Muhonen, Marc W. Pladet, P H Iverius, D K Strickland> ;The Journal of Biological Chemistry. 1993 Jul 5
• 107 citations
  Glycoprotein 330, a member of the low density lipoprotein receptor family, binds lipoprotein lipase in vitro.
  M Z Kounnas, D.A. Chappell, Dudley K. Strickland, William Scott Argraves> ;The Journal of Biological Chemistry. 1993 Jul 5
• 9 citations
  Regulation of LDL receptor expression by luminal sterol flux in CaCo-2 cells.
  F J Field, D Fujiwara, E Born, David A. Chappell, Satya N. Mathur> ;Arteriosclerosis and Thrombosis. 1993 May 1
• 140 citations
  The low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor binds and mediates catabolism of bovine milk lipoprotein lipase.
  David A. Chappell, Glenna L. Fry, M A Waknitz, P H Iverius, S E Williams, D K Strickland> ;The Journal of Biological Chemistry. 1992 Dec 25
• 19 citations
  Evidence for isomerization during binding of apolipoprotein-B100 to low density lipoprotein receptors.
  David A. Chappell, Glenna L. Fry, M A Waknitz, J J Berns> ;The Journal of Biological Chemistry. 1992 Jan 5
• Join now to see all