DavidCummingsDOMS

PubMed

• Ring substituents on substituted benzamide ligands indirectly mediate interactions with position 7.39 of transmembrane helix 7 of the D4 dopamine receptor.
  Ericksen SS, Cummings DF, Teer ME, Amdani S, Schetz JA> ;J. Pharmacol. Exp. Ther.. 2012-08-01
• Synthesis and structure-affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5-HT1A, 5-HT2A, 5-HT2C r...
  Cummings, D. F., Canseco, D. C., Sheth, P., Johnson, J. E., Schetz, J. A.> ;Bioorg Med Chem. 2010 Jul 1
• Transmembrane segment five serines of the D4 dopamine receptor uniquely influence the interactions of dopamine, norepinephrine, and Ro10-4548.
  Cummings, D. F., Ericksen, S. S., Goetz, A., Schetz, J. A.> ;J Pharmacol Exp Ther. 2010 Jun
• Three amino acids in the D2 dopamine receptor regulate selective ligand function and affinity.
  Cummings, D. F., Ericksen, S. S., Schetz, J. A.> ;J Neurochem. 2009 Jun 03
• Ligand selectivity of D2 dopamine receptors is modulated by changes in local dynamics produced by sodium binding.
  Ericksen, S. S., Cummings, D. F., Weinstein, H., Schetz, J. A.> ;J Pharmacol Exp Ther. 2008 Oct 14
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Journal Articles

• Ring substituents on substituted benzamide ligands indirectly mediate interactions with position 739 of transmembrane helix 7 of the D4 dopamine receptor  
  Ericksen SS, Cummings DF, Teer ME, Amdani S, Schetz JA, J Pharmacol Exp Ther, 1/1/2012
• Synthesis and structure-affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5-HT1A, 5-HT2A, 5-HT2C r...  
  Cummings DF, Canseco DC, Sheth P, Johnson JE, Schetz JA, Bioorg & Med Chem, 1/1/2010
• Transmembrane segment five serines of the D4 dopamine receptor uniquely influence the interactions of dopamine, norepinephrine and Ro10-4548  
  Cummings DF, Ericksen SS, Goetz A, Schetz, JA, J Pharmacol Exp Ther, 1/1/2010

Abstracts/Posters

• Confused and Demented: A Case of Hashimoto's Encephalopathy.
  Cummings DF, ACOFP National Convention, 1/1/2014
• It's Not the Bacteria! Altered Mental Status due to an Apoplectic Pituitary Macroadenoma in Sepsis.
  Cummings DF, Yerrabolu M, ACOFP National Convention, 1/1/2013
• An Unfortunate Case of Gastric Perforation in Crohn's Disease.
  Cummings DF, Pogue LD, Fernandes D, Kettering TO, ACOFP National Convention, 1/1/2012
• Serines in transmembrane helix five are key sites of agonist interaction with the D4 dopamine receptor.
  Cummings DF, Goetz A, Schetz JA, Research Appreciation Day, University of North Texas Health Science Center, 1/1/2009
• Intracellular sodium modulates the D2 dopamine receptor by inducing structural changes in transmembrane segment two.
  Cummings DF, Schetz JA, Research Appreciation Day, University of North Texas Health Science Center, 1/1/2008
• Discovery of a mutation in the D2 subtype of dopamine receptors that eliminates its functional response to quinpirole.
  Cummings DF, Chen S, Floresca CZ, Schetz JA, Research Appreciation Day, University of North Texas Health Science Center, 1/1/2006
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Lectures

• Modification of a subtype selectivity microdomain in the D2 dopamine receptor changes the affinity and function of L-750,667. 
  University of North Texas Health Science Center - 1/1/2007

Other

• Probing the Role of Transmembrane Segments Two and Three in the Activation State of the D2 Dopamine Receptor. 
  Cummings DF, Oral Presentation for Thesis Defense
  1/1/2009