DavidJosephDiemertMD

Infectious Disease • Washington, DC

International Health, Travel & Tropical

George Washington University

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Office
2300 Eye Street NW
Ross 723-D
Washington, DC 20037
Phone+1 202-994-2909
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Education & Training

University of AlbertaClass of 1995

Certifications & Licensure

MD State Medical License 2001 - 2024
DC State Medical License 2007 - 2024

Clinical Trials

Phase 1 Trial of Na-ASP-2 Hookworm Vaccine in Previously Infected Brazilian Adults Start of enrollment: 2007 May 01
Terminated
Phase 1
Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With or Without Additional Adjuvant in Brazilian Adults Start of enrollment: 2011 Nov 01
Completed
Phase 1
An Evaluation of a Novel Food Product in Adults Residing in an Area Endemic for Helminths Start of enrollment: 2011 Jan 01
Terminated
Not Applicable
Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With Different Doses of a Novel Adjuvant Start of enrollment: 2012 May 01
Completed
Phase 1
Safety and Immunogenicity Study of Na-GST-1 With or Without CpG Start of enrollment: 2014 Oct 01
Completed
Phase 1
A Phase Ib Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel)(R) With or Without AP 10-701 for Intestinal Schistosomiasis in Healthy Exposed Adults Start of enrollment: 2018 May 20
Completed
Phase 1
A Phase I Trial to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer Vaccine, Adjuvanted Start of enrollment: 2018 Jun 15
Completed
Phase 1
Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults Start of enrollment: 2019 Oct 07
Active, not recruiting
Phase 1, Phase 2
Controlled Human Infection Study of Orally Administered Trichuris Trichiura Eggs in Naïve Adults Start of enrollment: 2024 Jul 01
Not yet recruiting
Phase 1
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

1 citations
Safety and immunogenicity of the co-administered Na-APR-1 and Na-GST-1 hookworm vaccines in school-aged children in Gabon: a randomised, controlled, observer-blind, ph...
Jeannot F Zinsou, David J Diemert, Jean Claude Dejon-Agobé, Bayodé R Adégbité, Yabo Josiane Honkpehedji, Kafui G Vodonou, Rodrigue Bikangui, Jean Ronald Edoa, Margueri...> ;The Lancet. Infectious Diseases. 2024 Mar 18
2 citations
Safety and immunogenicity of the Na-APR-1 hookworm vaccine in infection-naïve adults.
David J Diemert, Maria Zumer, Doreen Campbell, Shannon Grahek, Guangzhao Li, Jin Peng, Maria Elena Bottazzi, Peter Hotez, Jeffrey Bethony> ;Vaccine. 2022 Oct 6
35 citations
Safety and immunogenicity of an AS03-adjuvanted SARS-CoV-2 recombinant protein vaccine (CoV2 preS dTM) in healthy adults: interim findings from a phase 2, randomised, ...
Saranya Sridhar, Arnel Joaquin, Matthew I Bonaparte, Agustin Bueso, Anne-Laure Chabanon, Aiying Chen, Roman M Chicz, David Diemert, Brandon J Essink, Bo Fu, Nicole A G...> ;The Lancet. Infectious Diseases. 2022 May 1
19 citations
Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose...
Ayola A. Adegnika, Sophia G. de Vries, Frejus Jeannot Zinsou, Yabo J Honkepehedji, Jean-Claude Dejon Agobe, Kafui G Vodonou, Rodrigue Bikangui, Aurore Bouyoukou Hounkp...> ;The Lancet. Infectious Diseases. 2021 Feb 1
5 citations
Assessing the Dissemination of COVID-19 Articles Across Social Media With Altmetric and PlumX Metrics: Correlational Study.
Haley Tornberg, Carine J Moezinia, Chapman Wei, Simone A. Bernstein, Chaplin Wei, Refka Al-Beyati, Theodore Quan, David Diemert> ;Journal of Medical Internet Research. 2021 Jan 14
5744 citations
Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Lindsey R. Baden, Hana M. El Sahly, Brandon Essink, Karen L. Kotloff, Sharon E. Frey, Rick Novak, David Diemert, Stephen A. Spector, Nadine Rouphael, C. Buddy Creech, ...> ;The New England Journal of Medicine. 2021 Feb 4
Correction: Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults.
David Diemert, Janaína de Moura Freire, Vanderson Valente, Carlo Geraldo Fraga, Frederico Talles, Shannon Grahek, Doreen Campbell, Amar R. Jariwala, Maria Victoria Per...> ;Plos Neglected Tropical Diseases. 2020 Aug 17
28 citations
A phase 1 study of the safety, reactogenicity, and immunogenicity of a Schistosoma mansoni vaccine with or without glucopyranosyl lipid A aqueous formulation (GLA-AF) ...
Wendy A. Keitel, G.E. Potter, David Diemert, Jeffrey M. Bethony, H. M. El Sahly, J.K. Kennedy, Shital M. Patel, Jordan L. Plieskatt, W. Jones, Gregory A. Deye, Maria E...> ;Vaccine. 2019 Oct 8
18 citations
Human challenge trials in vaccine development, Rockville, MD, USA, September 28–30, 2017
Marc Baay, Thomas L. Richie, Pieter Neels, Marco Cavaleri, Roma Chilengi, David Diemert, Stephen L. Hoffman, Robert A Johnson, Beth D. Kirkpatrick, Ivana Knezevic, Mat...> ;Biologicals. 2019 Sep 1
32 citations
Lessons along the Critical Path: Developing Vaccines against Human Helminths
David Diemert, Maria Elena Bottazzi, Jordan L. Plieskatt, Peter J. Hotez, Jeffrey M. Bethony> ;Trends in Parasitology. 2018 Sep 1
31 citations
Controlled Human Hookworm Infection: Accelerating Human Hookworm Vaccine Development.
David Diemert, Doreen Campbell, Jill Brelsford, Caitlyn Leasure, Guangzhao Li, Jin Peng, Maria Zumer, Naji Younes, Maria Elena Bottazzi, Rojelio Mejia, David I. Pritch...> ;Open Forum Infectious Diseases. 2018 May 1
50 citations
Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults
David Diemert, Janaína de Moura Freire, Vanderson Valente, Carlos Geraldo Fraga, Frederico Talles, Shannon Grahek, Doreen Campbell, Amar R. Jariwala, Maria Victoria Pe...> ;Plos Neglected Tropical Diseases. 2017 May 2
9 citations
Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine.
Jill Brelsford, Jordan L. Plieskatt, Anna Yakovleva, Amar R. Jariwala, Brian Keegan, Jin Peng, Pengjun Xia, Guangzhao Li, Doreen Campbell, Maria Victoria Periago, Rodr...> ;Plos Neglected Tropical Diseases. 2017 Feb 13
10 citations
A Comparison of the Quality of Informed Consent for Clinical Trials of an Experimental Hookworm Vaccine Conducted in Developed and Developing Countries.
David Diemert, Lucas Lobato, Ashley Styczynski, Maria Zumer, Amanda Nathale Soares, Maria Flávia Gazzinelli> ;Plos Neglected Tropical Diseases. 2017 Jan 23
10 citations
Improving the understanding of schistosomiasis among adolescents in endemic areas in Brazil: A comparison of educational methods
Maria Flávia Gazzinelli, Lucas Lobato, Gisele Nepomuceno de Andrade, Leonardo Ferreira Matoso, David Diemert, Andrea Gazzinelli> ;Patient Education and Counseling. 2016 Oct 1
88 citations
The Global Economic and Health Burden of Human Hookworm Infection
Sarah M. Bartsch, Peter J. Hotez, Lindsey Asti, Kristina M. Zapf, Maria Elena Bottazzi, David Diemert, Bruce Y. Lee> ;Plos Neglected Tropical Diseases. 2016 Sep 8
25 citations
Modeling the economic and epidemiologic impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting.
Sarah M. Bartsch, Peter J. Hotez, Daniel L. Hertenstein, David Diemert, Kristina M. Zapf, Maria Elena Bottazzi, Jeffrey M. Bethony, Shawn T. Brown, Bruce Y. Lee> ;Vaccine. 2016 Apr 27
20 citations
The Right Tool for the Job: Detection of Soil-Transmitted Helminths in Areas Co-endemic for Other Helminths
Maria Victoria Periago, Renata C. Diniz, Simone A. Pinto, Anna Yakovleva, Rodrigo Correa-Oliveira, David Diemert, Jeffrey M. Bethony> ;Plos Neglected Tropical Diseases. 2015 Aug 4
5 citations
Update on prevention and treatment of intestinal helminth infections.
Paul Blair, David Diemert> ;Current Infectious Disease Reports. 2015 Mar 29
43 citations
Impact of gender on the decision to participate in a clinical trial: a cross-sectional study
Lucas Lobato, Jeffrey M. Bethony, Fernanda Bicalho Pereira, Shannon Grahek, David Diemert, Maria Flávia Gazzinelli> ;BMC Public Health. 2014 Nov 6
26 citations
Microproteinuria during Opisthorchis viverrini Infection: A Biomarker for Advanced Renal and Hepatobiliary Pathologies from Chronic Opisthorchiasis
Prasert Saichua, Paiboon Sithithaworn, Amar R. Jariwala, David J. Deimert, Jiraporn Sithithaworn, Banchob Sripa, Thewarach Laha, Eimorn Mairiang, Chawalit Pairojkul, M...> ;Plos Neglected Tropical Diseases. 2013 May 23
79 citations
The human hookworm vaccine
Peter J. Hotez, David Diemert, Kristina M. Bacon, Coreen M. Beaumier, Jeffrey M. Bethony, Maria Elena Bottazzi, Simon Brooker, Artur Roberto Couto, Marcos da Silva Fre...> ;Vaccine. 2013 Apr 18
17 citations
Serum CCL11 (eotaxin-1) and CCL17 (TARC) are serological indicators of multiple helminth infections and are driven by Schistosoma mansoni infection in humans
Stefan M. Geiger, Anne Jardim-Botelho, Weston Williams, Neal Alexander, David Diemert, Jeffrey M. Bethony> ;Tropical Medicine & International Health. 2013 Jun 1
19 citations
Fusion of Na-ASP-2 with human immunoglobulin Fcγ abrogates histamine release from basophils sensitized with anti-Na-ASP-2 IgE.
Bin Zhan, Helton C. Santiago, Brian Keegan, Portia M. Gillespie, Jian Xue, Jeffrey M. Bethony, L. M. De Oliveira, Desheng Jiang, David Diemert, S-H Xiao, Karen Jones, ...> ;Parasite Immunology. 2012 Aug 1
27 citations
Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines.
Mark S. Pearson, Leon Tribolet, Cinzia Cantacessi, Maria Victoria Periago, Maria Adela Valerio, Amar R. Jariwala, Peter J. Hotez, David Diemert, Alex Loukas, Jeffrey M...> ;The Journal of Allergy and Clinical Immunology. 2012 Jul 1
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Press Mentions

Pfizer RSV Vaccine Trials Show Protection for Infants and Older AdultsApril 7th, 2023
mRNA HIV Vaccine Achieves 97 Percent Efficacy in SMHS Human TrialsJanuary 30th, 2023
Scientists Reveal Encouraging Findings in First-in-Human Clinical Trial Evaluating HIV Vaccine ApproachDecember 2nd, 2022
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Hospital Affiliations

George Washington University HospitalWashington, District of Columbia

DavidJosephDiemertMD

Dr. Diemert is on Doximity

Education & Training

Certifications & Licensure

Clinical Trials

Publications & Presentations

Press Mentions

Hospital Affiliations

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