DavidHoadleyEllisonMD

PubMed

• Serum Bicarbonate as a Surrogate for pH in Hemodialysis: A Pilot Study.
  Woodell, T. B., Rifkin, D. E., Ellison, D. H., Negoianu, D., Weiss, J. W.> ;Kidney medicine. 2020 Oct 6
• The authors reply.
  Ellison, D. H., Palmer, B. F.> ;Kidney international. 2020 Aug 24
• Kidney Is Essential for Blood Pressure Modulation by Dietary Potassium.
  Su, X., Yang, C., Ellison, D. H.> ;Current cardiology reports. 2020 Aug 14
• Effect of Angiotensin II on ENaC in the Distal Convoluted Tubule and in the Cortical Collecting Duct of Mineralocorticoid Receptor Deficient Mice.
  Wu, P., Gao, Z., Zhang, D., Duan, X., Terker, A. S., Lin, D., Ellison, D. H., Wang, W.> ;Journal of the American Heart Association. 2020 Mar 27
• Tacrolimus-induced hypomagnesemia and hypercalciuria requires FKBP12 suggesting a role for calcineurin.
  Gratreak, B. D., Swanson, E. A., Lazelle, R. A., Jelen, S. K., Hoenderop, J., Bindels, R. J., Yang, C., Ellison, D. H.> ;Physiological reports. 2020 Jan 8
• Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
  Catherine M. Clase, Juan Jesus Carrero, David H. Ellison, Morgan E. Grams, Brenda R. Hemmelgarn, Meg Jardine, Csaba P. Kovesdy, Gregory A. Kline, Gregor Lindner, Grego...> ;Kidney International. 2020 Jan 1
• Hypertension-causing cullin 3 mutations disrupt COP9 signalosome binding.
  Cornelius, R. J., Yang, C., Ellison, D. H.> ;American journal of physiology. Renal physiology. 2019 Dec 10
• WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia.
  Thomson, M. N., Cuevas, C. A., Bewarder, T. M., Dittmayer, C., Miller, L. N., Si, J., Cornelius, R. J., Su, X., Yang, C., McCormick, J. A., Hadchouel, J., Ellison, D. ...> ;American journal of physiology. Renal physiology. 2019 Nov 19
• WNK4 limits distal calcium losses following acute furosemide treatment.
  Ferdaus, M. Z., Gratreak, B. D., Miller, L., Si, J., McCormick, J. A., Yang, C., Ellison, D. H., Terker, A. S.> ;Physiological reports. 2019 Sep 10
• Optical tissue clearing and immunolabeling in kidney research.
  Su, X., Saritas, T., Ellison, D. H.> ;Methods in cell biology. 2019 Sep 9
• Optical Clearing and Imaging of Immunolabeled Kidney Tissue.
  Saritas, T., Puelles, V. G., Su, X., Ellison, D. H., Kramann, R.> ;Journal of visualized experiments : JoVE. 2019 Aug 6
• Enemy Action in the Distal Convoluted Tubule.
  Ellison, D. H., Lin, S.> ;Journal of the American Society of Nephrology : JASN. 2019 Aug 2
• Renal-Tubule Epithelial Cell Nomenclature for Single-Cell RNA-Sequencing Studies.
  Lihe Chen, Jevin Z Clark, Jonathan W. Nelson, Brigitte Kaissling, David H. Ellison, Mark A. Knepper> ;Journal of The American Society of Nephrology. 2019 Jun 28
• Mechanistic Insights into Loop Diuretic Responsiveness in Heart Failure.
  Ellison, D. H.> ;Clinical journal of the American Society of Nephrology : CJASN. 2019 May 9
• Clinical Pharmacology in Diuretic Use.
  Ellison, D. H.> ;Clinical journal of the American Society of Nephrology : CJASN. 2019 Apr 3
• Salt-sensitive transcriptome of isolated kidney distal tubule cells.
  Elizabeth A. Swanson, Jonathan W. Nelson, Sophia Jeng, Kayla J. Erspamer, Chao Ling Yang, Shannon K. McWeeney, David H. Ellison> ;Physiological Genomics. 2019 Mar 15
• Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal K+ excretion.
  Xiao Tong Su, David H. Ellison, Wen-Hui Wang> ;American Journal of Physiology-renal Physiology. 2019 Mar 1
• Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney.
  Martin N. Thomson, Wolfgang Schneider, Kerim Mutig, David H. Ellison, Ralph Kettritz, Sebastian Bachmann> ;American Journal of Physiology-renal Physiology. 2019 Feb 1
• Separate and interacting effects of the endogenous circadian system and behaviors on plasma aldosterone in humans.
  Thosar, S. S., Rueda, J. F., Berman, A. M., Lasarev, M. R., Herzig, M. X., Clemons, N. A., Roberts, S. A., Bowles, N. P., Emens, J. S., Ellison, D. H., Shea, S. A.> ;American journal of physiology. Regulatory, integrative and comparative physiology. 2018 Dec 7
• Optical Clearing in the Kidney Reveals Potassium-Mediated Tubule Remodeling.
  Turgay Saritas, Victor G. Puelles, Xiao-Tong Su, James A. McCormick, Paul A. Welling, David H. Ellison> ;Cell Reports. 2018 Dec 4
• Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway.
  Ryan J. Cornelius, Jinge Si, Catherina A. Cuevas, Jonathan W. Nelson, Brittany D.K. Gratreak, Ruggero Pardi, Chao Ling Yang, David H. Ellison> ;Journal of The American Society of Nephrology. 2018 Nov 1
• C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity.
  Murillo-de-Ozores, A. R., Rodríguez-Gama, A., Bazúa-Valenti, S., Leyva-Ríos, K., Vázquez, N., Pacheco-Álvarez, D., De La Rosa-Velázquez, I. A., Wengi, A., Stone, K. L....> ;The Journal of biological chemistry. 2018 Jun 21
• Dual Gain and Loss of Cullin 3 Function Mediates Familial Hyperkalemic Hypertension
  David Ellison, MD> ;National Institutes of Health. 2018 Jun 14
• The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway.
  Bazúa-Valenti, S., Rojas-Vega, L., Castañeda-Bueno, M., Barrera-Chimal, J., Bautista, R. A., Cervantes-Pérez, L. G., Vázquez, N., Plata, C., Murillo-de-Ozores, A. R., ...> ;Journal of the American Society of Nephrology : JASN. 2018 Jun 1
• Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC.
  Argaiz, E. R., Chavez-Canales, M., Ostrosky-Frid, M., Rodríguez-Gama, A., Vázquez, N., Gonzalez-Rodriguez, X., Garcia-Valdes, J., Hadchouel, J., Ellison, D., Gamba, G.> ;American journal of physiology. Renal physiology. 2018 May 31
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Journal Articles

• Renal COP9 Signalosome Deficiency Alters cul3-klhl3-WNK Signaling Pathway  
  David Ellison, MD, Journal of the American Society of Nephrology
• The Calcium-Sensing Receptor Increases Activity of the Renal NCC Through the WNK4-SPAK Pathway  
  David Ellison, MD, Journal of the American Society of Nephrology
• Evaluating Hyponatremia  
  Cohen DM, Ellison DH, JAMA, 1/1/2015
• Why Your Mother Was Right: How Potassium Intake Reduces Blood Pressure  
  Ellison DH, Terker AS, Trans Am ClinClimatol Assoc, 1/1/2015
• Bardoxolone methyl in type 2 diabetes and advanced chronic kidney disease  
  Ellison, DH, N Engl J Med, 1/1/2014
• PharmGKB summary: Diuretics pathway, pharmacodynamics  
  Thorn CF, Ellison DH, Turner ST, Altman RB, Klein TE, Pharmacogenet Genomics, 1/1/2013
• A SPAK isoform switch modulates renal salt transport and blood pressure  
  McCormick JA, Mutig K, Nelson JH, Saritas T, Hoorn EJ, Yang CL, Rogers S, Curry J, Delpire E, Bachmann S, and Ellison DH, Cell Metabolism, 1/7/2011
• The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension  
  Hoorn EJ, Walsh SB, McCormick JA, Furstenberg A, Yang CL, Roeschel T, Paliege A, Howie AJ, Conley J, Bachmann S, Unwin RJ, Ellison DH, SeminNephrol, 1/1/2011
• Welling PAWNK1 kinase isoform switch regulates renal potassium excretion  
  Wade JB, Fang L, Liu J, Li D, Yang CL, Subramanya AR, Maouyo D, Mason A, Ellison DH, ProcNatlAcadSci U S A, 1/30/2006
• Disorders of Sodium and Water Core Curriculum in Nephrology  
  Ellison DH, Am J Kidney Disease, 1/1/2005
• Comparison of WNK4 and WNK1 kinase and inhibiting activities  
  Wang Z, Yang CL, Ellison DH, BiochemBiophys Res Commun, 1/7/2004
• The thiazide-sensitive Na-Cl cotransporter and human disease: reemergence of an old player  
  Ellison DH, J Am SocNephrol, 1/1/2003
• WNK kinases regulate thiazide-sensitive Na-Clcotransport  
  Yang CL, Angell J, Mitchell R, Ellison DH, J Clin Invest, 1/1/2003
• Renal expression of sodium transporters and aquaporin-2 in hypothyroid  
  Schmitt R, Klussmann E, Kahl T, Ellison DH, Bachmann S, Am J Physiol Renal Physiol, 1/1/2003
• Loop Diuretic Infusion Increases Thiazide-Sensitive Na-Cl Cotransporter Expression by an Aldosterone-Dependent Mechanism  
  Abdallah JG, Schrier RW, Edelstein C, Jennings SD, Wyse B, Ellison DH, J.Am. Soc.Nephrol, 1/1/2001
• The distal convoluted tubule of the rabbit kidney does not express a functional sodium channel  
  Velazquez H, Silva T, Andujar E, Desir GV,Ellison DH, Greger R, Am. J. Physiol. Renal Physiol, 1/1/2001
• The Mammalian Distal Tubule:Physiology Pathophysiology and Molecular Anatomy  
  Reilly RF, Ellison DH, Physiological Reviews, 1/1/2000
• Divalent cation transport by the distal nephron: insights from Bartter’s and Gitelman’s syndromes  
  Ellison DH, Am J Physiol Renal Physiol, 1/1/2000
• Calcium and sodium transport by the distal convoluted tubule of the rat  
  Costanzo LS, Windhager EE, Ellison DH, J Am SocNephrol, 1/1/2000
• Developmental expression of sodium entry pathways in rat nephron  
  Schmitt R,Ellison DH, Farman N, Rossier B, Reilly RF, Reeves WB, Oberbäumer I, Tapp R, Bachmann S, Am.J.Physiol.Renal, 1/1/1999
• Defective processing and expression of the thiazide-sensitive NaCl cotransporter as a cause of Gitelman’s Syndrome  
  Kunchaparty S, Palcso M, Berkman J, Velazquez H, Desir GV, Bernstein P, Reilly RF, Ellison DH, Am. J. Physiol, 1/1/1999
• Diuretic Resistance: Physiology and Therapeutics  
  Ellison D.H, Seminars in Nephrology, 1/1/1999
• Sodium transport-related proteins in the mammalian distal nephron-distribution, ontogeny and functional aspects  
  Bachmann S, Bostanjoglo M, Schmitt R,Ellison DH, Anat. Embryol, 1/1/1999
• 11beta-hydroxysteroid dehydrogenase, mineralocorticoid receptor and thiazide-sensitive Na-Cl cotransporter expression by distal tubules  
  Bostanjoglo M, Reeves WB, Reilly FF, Velázquez H, Robertson N, Litwack G, Morsing P, Dœrup J, Bachmann S, Ellison DH, J.Am. Soc.Nephrol, 1/1/1998
• The distal convoluted tubule of the rabbit coexpresses NaCl cotransporter and 11-hydroxysteroid dehydrogenase 2  
  Velazquez H, Naray-Fejes-Tøth A, Silva T, Andujar E, Reilly RF, Desir G, Ellison DH, Kidney International, 1/1/1998
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Books/Book Chapters

• Endocrine Emergencies: Recognition and Treatment 
  Chapter: SIADH 
  Page 115 - 126Ellison, D.H. HyponatremiaEditors: D.L. Loriaux.Springer Science+Business Media, New York, NY2014
• Endocrine Emergencies: Recognition and Treatment 
  Chapter: Diabetes Insipidus 
  Page 127 - 138Ellison, D.HEditors: D.L. Loriaux.Springer Science+Business Media, New York, NY2014
• Core Concepts in the Disorders of Fluid, Electrolytes, and Acid-Base Balance 
  Chapter: Diuretic Therapy 
  Subramanya, AR and Ellison, DHEditors: DB Mount, MH Sayegh, AK Singh.Springer, New York, NY2013
• Schrier’s Diseases of the Kidney 
  Chapter: Mechanisms of Diuretic Action 
  Ellison, D.H., Hoorn, E.J., Schrier, R.WEditors: TM Coffman, FJ Falk, BM Molitoris, EG Neilson, and RW Schrier.Wolters Kluwer, Philadelphia, PA2013
• Nephrology Secrets 
  Chapter: Genetic Disorders of Sodium Transport 
  Maddirala S, Ellison DHEditors: Lerma, EV and Nissenson AR.Elsevier2012
• Nephrology Secrets 
  Chapter: Management of the patient with congestive heart failure 
  Rueda J, Ellison DHEditors: Lerma, EV and Nissenson AR.Elsevier2012
• Brenner & Rector’s The Kidney 
  Chapter: Diuretics 
  Ellison DH,Hoorn EJ, Wilcox CSEditors: Maarten W. Taal, Glenn M. Chertow, Philip A. Marsden, Karl Skorecki, Alan S.L. Yu, Barry M. Brenner.Elesvier, Philadelphia, PAEdition 9th,2012
• Seldin and Giebisch’sThe Kidney 
  Chapter: Physiology and Pathophysiology of Diuretic Action 
  Ellison, D.H2012
• Current Diagnosis & Treatment: Nephrology & Hypertension 
  Chapter: Disorders of Extracellular Volume: Hypovolemia and Hypervolemia 
  Ellison D.HEditors: Edgar V. Lerma, Jeffry S. Berns, Allen R. Nissenson.McGraw Hill Medical, New York, NY2009
• Brenner and Rector’s The Kidney 
  Chapter: Diuretics 
  Ellison DH,Wilcox C.SEdition 8th,2008
• Seldin and Giebisch’s The Kidney 
  Chapter: Physiology and Pathophysiology of Diuretic Action 
  Okusa, M.D., Ellison, DHEditors: Alpern, R, Hebert, S.C.2008
• Molecular and Genetic Basis of Renal Disease 
  Chapter: Hereditary disorders of collecting duct sodium and potassium transport 
  Ellison DH, Thomas CPEditors: Mount, DB and Pollak, MR.Saunders, Philadelphia, PA2008
• Therapy in Nephrology and Hypertension 
  Chapter: Diuretic Use in Edema and the Problem of Resistance 
  Ellison DH, Wilcox CEditors: Wilcox CS.W.B. Saunders CompanyEdition 3rd,2008
• Heart Failure 
  Chapter: Diuretics in congestive heart failure 
  Ross A, Hershberger RE, Ellison DHEditors: AM Feldman.Blackwell2006
• Primer on Kidney Diseases 
  Chapter: Edema and the Clinical Use of Diuretics 
  Ellison DHEditors: Greenberg A, Cheung AK, Coffman TM, Falk RJ, Jennette JC.National Kidney Foundation, Elsevier Saunders2005
• Therapy in Nephrology and Hypertension 
  Chapter: Diuretics: Use in Edema and the Problem of Resistance 
  Ellison DH, Wilcox CEditors: Brady HR & Wilcox CS.W.B. Saunders CompanyEdition 2nd,2003
• Acid-Base and Electrolyte Disorders 
  Chapter: Salt Wasting Disorders 
  Ellison DHEditors: DuBose TD, Hamm LL.W.B. Saunders Company2002
• Diseases of the Kidney and Urinary Tract 
  Chapter: Mechanisms of Diuretic Action 
  Ellison DH, Okusa MD. Schrier, R.WLippincott Williams & Wilkins, Philadelphia, PAEdition 7th,2001
• The Kidney: Physiology and Pathophysiology 
  Chapter: Physiology and pathophysiology of diuretic action 
  Okusa MD,Ellison DHEditors: Seldin, D.W. Giebisch.G.Academic Press, San Diego, CAEdition 3rd,1999
• Atlas of Diseases of the Kidney 
  Chapter: Disorders of Sodium Balance 
  Ellison DHEditors: R.W. Schrier.Current Medicine, Philadelphia, PA1999
• Manual of Nephrology 
  Chapter: The Edematous Patient: Cardiac Failure, Cirrhosis, and Nephrotic Syndrome 
  Page 1 - 20Ellison DH, Schrier RWEditors: R.W. Schrier.Little, Brown and Company1999
• Therapy in Nephrology and Hypertension 
  Chapter: Diuretic Resistance 
  Ellison DH.& Wilcox, CEditors: Brady H. R. & Wilcox, C.S..W.B. Saunders Company1998
• Principles of Medical Biology 
  Chapter: The physiologic basis of diuretic drug action and synergism 
  Page 577 - 599Ellison DHEditors: E.E. Bittar& N. Bittar.JAI Press, Inc, Greenwich, CT1997
• Clinical Physiology and Use of Diuretic Agents 
  Chapter: Adaptation to Diuretic Drugs 
  Page 209 - 231Ellison DHEditors: D. Seldin, G. Giebisch.Academic Press1997
• Clinical Physiology and Use of Diuretic Agents 
  Chapter: Circulatory Support: Dopamine and Dopamine Agonists as Adjuncts to Diuretic Therapy 
  Page 301 - 319Ellison DHEditors: D. Seldin, G. Giebisch.Academic Press1997
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Lectures

• Diuretic Resistance 
  Washington, DC - 1/1/2015
• Aldosterone action on the kidney 
  New York, NY - 1/1/2015
• From Genes to Bedside 
  Nigmegen, Nethterlands - 1/1/2014
• Potassium and Blood Pressure 
  Berlin, Germany - 1/1/2014
• Renal Medicine 
  Aspen, CO - 1/1/2014
• WNK and NCC 
  Dallas, TX - 1/1/2013
• Salt Sensitive Hypertension: Basic Perspective’ 
  Los Angeles, CA - 1/1/2012
• Aldosterone and the DCT 
  Cairns, Australia - 1/1/2012
• Aldosterone and the Distal Tubule 
  Houston, TX - 1/1/2012
• Sodium and Potassium in Health and Disease 
  Geneva, Switzerland - 1/1/2012
• Gordon Syndrome 
  Boston, MA - 1/1/2012
• WNK Kinases, Tacrolimus, and Blood Pressure 
  San Francisco, CA - 1/1/2012
• Rational Approach to Diuretic Resistance and A Novel Signaling Pathway in the Distal Nephron Regulates Salt Balance and Blood Pressure 
  1/1/2012
• SPAK and WNK: positive and negative regulators of salt transport 
  Berlin, Germany - 1/1/2011
• Regulation of NaCl Cotransport 
  1/1/2011
• WNK Kinases and the Distal Nephron 
  1/1/2011
• A Practical Approach to Diuretic Resistance 
  1/1/2010
• Mechanisms of Diuretic Resistance 
  1/1/2010
• WNK kinases 2010: An update 
  1/1/2010
• WNKs regulate NaCl cotransport 
  Saxons River, VT - 1/1/2010
• Mechanisms of sodium chloride co-transport regulation by a WNK signalling complex’ 
  Manila, Phillippines, 2010; Zurich, Switzerland, 2009 - 1/1/2010
• WNK signaling complex 
  1/1/2009
• Treatment of Diuretic Resistance’ 
  1/1/2009
• How potassium lowers blood pressure: lessons from a rare disease 
  1/1/2009
• Getting water from a stone: lessons in diuretic resistance’ 
  1/1/2008
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Other

• Syndrome of Inappropriate Antidiuretic Hormone Sections 
  Ellison DH, American College of Physicians, PIER