DavidWalterEssexMD

PubMed

• Recent advances in vascular thiol isomerases and redox systems in platelet function and thrombosis.
  Lu Wang, David W Essex> ;Journal of Thrombosis and Haemostasis. 2024 Mar 20
• 5 citations
  A novel role for endoplasmic reticulum protein 46 (ERp46) in platelet function and arterial thrombosis in mice.
  Junsong Zhou, Yi Wu, Lubica Rauova, Gavin T. Koma, Lu Wang, Mortimer Poncz, Hong Li, Tong Liu, Karen P. Fong, Joel S. Bennett, Satya P. Kunapuli, David W. Essex> ;Blood. 2021 Nov 9
• 17 citations
  Vascular thiol isomerases in thrombosis: The yin and yang.
  Yi Wu, David W. Essex> ;Journal of Thrombosis and Haemostasis. 2020 Nov 1
• 4 citations
  Mediastinal Lymphoma Presenting in Cardiogenic Shock with Superior Vena Cava Syndrome in a Primigravida at Full Term: Salvage Resection after Prolonged Extracorporeal ...
  Sabrina E Carro, David W. Essex, Mohamed Alsammak, Ashish Bains, Yoshiya Toyoda, Suresh Keshavamurthy> ;Case Reports in Oncology. 2019 Jun 4
• 12 citations
  The b' domain of protein disulfide isomerase cooperates with the a and a' domains to functionally interact with platelets.
  Lu Wang, Junsong Zhou, Lei Wang, Chih‐chen Wang, David W. Essex> ;Journal of Thrombosis and Haemostasis. 2019 Feb 1
• 19 citations
  The transmembrane protein disulfide isomerase TMX1 negatively regulates platelet responses
  Zhenzhen Zhao, Yi Wu, Junsong Zhou, Fengwu Chen, Aizhen Yang, David W. Essex> ;Blood. 2019 Jan 17
• 24 citations
  Multiple protein disulfide isomerases support thrombosis.
  David W. Essex, Yi Wu> ;Current Opinion in Hematology. 2018 Sep 1
• 13 citations
  Protein disulfide isomerase enhances tissue factor-dependent thrombin generation.
  Fengwu Chen, Zhenzhen Zhao, Junsong Zhou, Yi Lu, David W. Essex, Yi Wu> ;Biochemical and Biophysical Research Communications. 2018 Jun 18
• 38 citations
  The disulfide isomerase ERp72 supports arterial thrombosis in mice.
  Junsong Zhou, Yi Wu, Fengwu Chen, Lu Wang, Lubica Rauova, Vincent Hayes, Mortimer Poncz, Hong Li, Tong Liu, Junling Liu, David W. Essex> ;Blood. 2017 Aug 10
• 7 citations
  A new antithrombotic strategy: inhibition of the C-terminal active site of protein disulfide isomerase.
  Lu Wang, David W. Essex> ;Journal of Thrombosis and Haemostasis. 2017 Feb 28
• 2 citations
  P2Y12 receptor inhibition and LPS-induced coagulation.
  David W. Essex, A. Koneti Rao> ;Clinical Science. 2016 Mar 1
• 68 citations
  The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis
  Junsong Zhou, Yi Wu, Lu Wang, Lubica Rauova, Vincent Hayes, Mortimer Poncz, David W. Essex> ;The Journal of Clinical Investigation. 2015 Dec 1
• 24 citations
  The disulfide isomerase ERp57 is required for fibrin deposition in vivo
  Junsong Zhou, Yi Wu, Lu Wang, Lubica Rauova, Vincent Hayes, Mortimer Poncz, David W. Essex> ;Journal of Thrombosis and Haemostasis. 2014 Nov 1
• 65 citations
  Platelet-derived ERp57 mediates platelet incorporation into a growing thrombus by regulation of the αIIbβ3 integrin.
  Lu Wang, Yi Wu, Junsong Zhou, Syed S. Ahmad, Bulent Mutus, Natalio Garbi, Günter J. Hämmerling, Junling Liu, David W. Essex> ;Blood. 2013 Nov 21
• 72 citations
  The disulfide isomerase ERp57 mediates platelet aggregation, hemostasis, and thrombosis.
  Yi Wu, Syed S. Ahmad, Junsong Zhou, Lu Wang, Matthew P. Cully, David W. Essex> ;Blood. 2012 Feb 16
• 23 citations
  Vicinal thiols are required for activation of the αIIbβ3 platelet integrin.
  N. Manickam, S. S. Ahmad, David W. Essex> ;Journal of Thrombosis and Haemostasis. 2011 Jun 1
• 84 citations
  Redox Control of Platelet Function
  David W. Essex> ;Antioxidants & Redox Signaling. 2009 Apr 7
• 11 citations
  Glutathione regulates integrin αIIbβ3-mediated cell adhesion under flow conditions
  Chalmette Ball, K. Vinod Vijayan, Trung C. Nguyen, Kim Anthony, Paul F. Bray, David W. Essex, Jing-fei Dong> ;Thrombosis and Haemostasis. 2008 Nov 1
• 13 citations
  Thiols in the αIIbβ3 integrin are necessary for platelet aggregation
  Nagaraj Manickam, Xiuhua Sun, Kevin Hakala, Susan T. Weintraub, David W. Essex> ;British Journal of Haematology. 2008 Aug 1
• 46 citations
  Protein disulphide isomerase in platelet function
  Nagaraj Manickam, Xiuhua Sun, Mengru Li, Yair Gazitt, David W. Essex> ;British Journal of Haematology. 2007 Nov 20
• 32 citations
  Platelet surface glutathione reductase-like activity.
  David W. Essex, Mengru Li, Richard D. Feinman, Anna Miller> ;Blood. 2004 Sep 1
• 62 citations
  The role of thiols and disulfides in platelet function
  David W. Essex> ;Antioxidants & Redox Signaling. 2004 Jul 28
• 132 citations
  Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin α2β1
  Judith Lahav, Eveline M. Wijnen, Oded Hess, Samir W. Hamaia, Delia Griffiths, Michael Makris, C. Graham Knight, David W. Essex, Richard W. Farndale> ;Blood. 2003 Sep 15
• Redox control of platelet aggregation.
  Essex, D.W., Li, M.> ;Biochemistry. 2003 Jan 14
• 100 citations
  Successful use of recombinant activated factor VII for trauma-associated hemorrhage in a patient without preexisting coagulopathy.
  Patricia A. O'neill, Martin Bluth, Elizabeth S. Gloster, Devdas Wali, Soula Priovolos, Therese M. Dimaio, David W. Essex, Charles A. Catanese, Robert A. Strauss> ;The Journal of Trauma. 2002 Feb 1
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Journal Articles

• The Transmembrane Protein Disulfide Isomerase TMX1 Negatively Regulates Platelet Responses  
  David Essex, MD, Blood