DavidAugustusFiellinMD

Addiction Medicine

Professor, Internal Medicine, Emergency Medicine, Public Health, Yale School of Medicine Vice Chief, Faculty Affairs, General Internal Medicine Director, Program in Addiction Medicine

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Office
789 Howard Ave
Ynhh
New Haven, CT 06519
Phone+1 203-688-2471

Fax+1 203-688-4516
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Education & Training

Yale-New Haven Medical CenterResidency, Internal Medicine, 1991 - 1994
Emory University School of MedicineClass of 1991

Certifications & Licensure

CT State Medical License 1994 - 2025
American Board of Preventive Medicine Addiction Medicine

Clinical Trials

Buprenorphine and Integrated HIV Care Evaluation Start of enrollment: 2005 Aug 01
Unknown status
Phase 4
Buprenorphine Maintenance vs. Detoxification in Prescription Opioid Dependence Start of enrollment: 2008 Jul 01
Completed
Phase 4
Testing a Primary Care Model for the Treatment of Opioid Dependence Using Long-acting Injectable Naltrexone (Vivitrol). Start of enrollment: 2011 May 01
Withdrawn
Not Applicable
Pharmacotherapy for HIV Infected Patients With Alcohol Problems Start of enrollment: 2009 Jan 01
Withdrawn
Phase 4
The Prevalence of HIV Drug Resistance and Transmission Risk in Opioid Agonist Treatment Start of enrollment: 2008 Jun 01
Completed
Integrated Stepped Care for Unhealthy Alcohol Use in HIV Start of enrollment: 2013 Jan 01
Completed
Not Applicable
Working With HIV Clinics to Adopt Addiction Treatments Using Implementation Facilitation Start of enrollment: 2016 Sep 01
Completed
Not Applicable
Opioid Use Disorder in the Emergency Department: CTN 0069 Start of enrollment: 2017 Apr 03
Completed
Not Applicable
Financial Incentives, Randomization With Stepped Treatment Trial Start of enrollment: 2018 May 01
Completed
Not Applicable
Emergency Department-Initiated Buprenorphine Validation Network Trial Start of enrollment: 2020 Jul 08
Recruiting
Phase 2
Roles: Contact, Principal Investigator, Sub-Investigator
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Publications & Presentations

PubMed

Stepped Care for Patients to Optimize Whole Recovery (SC-POWR): An Effectiveness Trial Evaluating a Stepped Care Model for Individuals With Opioid Use Disorder and Chr...
Raiza Rossi, Christopher J Cutter, Mark Beitel, Mikah Covelli, Robert D Kerns, Svetlana Vassilieva, Deborah Olabisi, David A Fiellin, Declan T Barry> ;Substance Use & Addiction Journal. 2024 Apr 12
Accessibility of Opioid Treatment Programs Based on Conventional vs Perceived Travel Time Measures.
Junghwan Kim, Jinhyung Lee, Thomas A Thornhill, Julia Dennett, Haidong Lu, Benjamin Howell, Lauretta E Grau, David A Fiellin, Robert Heimer, Gregg Gonsalves> ;JAMA Network Open. 2024 Feb 5
The MATE Act: Progress for substance use education, but is checking a box enough?
Morford, K., Tetrault, J., Fiellin, D.> ;Journal of General Internal Medicine. 2024 Feb 2
1 citations
Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016-17.
Heimer, R., Black, A., Lin, H., Grau, L., Howell, B., Hawk, K., D'Onofrio, G., Becker, W., Fiellin, D.> ;Drug and Alcohol Dependence. 2024 Jan 1
Alcohol Use and Sustained Virologic Response to Hepatitis C Virus Direct-Acting Antiviral Therapy.
Emily J Cartwright, Chloe Pierret, Caroline Minassian, Denise A Esserman, Janet P Tate, Matthew B Goetz, Debika Bhattacharya, David A Fiellin, Amy C Justice, Vincent L...> ;JAMA Network Open. 2023 Sep 5
Perspectives on contingency management for alcohol use and alcohol-associated conditions among people in care with HIV.
Shawn M Cohen, Dominick DePhilippis, Yanhong Deng, James Dziura, Tekeda Ferguson, Lisa M Fucito, Amy C Justice, Stephen Maisto, Vincent C Marconi, Patricia Molina, Man...> ;Alcohol, Clinical & Experimental Research. 2023 Sep 1
URINE TOXICOLOGY PROFILES OF EMERGENCY DEPARTMENT PATIENTS WITH UNTREATED OPIOID USE DISORDER: A MULTI-SITE VIEW.
Ethan Cowan, Jeanmarie Perrone, James Dziura, E Jennifer Edelman, Kathryn Hawk, Andrew Herring, Ryan McCormack, Alexandra Murphy, Manali Phadke, David A Fiellin, Gail ...> ;The Journal of Emergency Medicine. 2023 Oct 1
Efficacy of alcohol reduction interventions among people with HIV as evaluated by self-report and a phosphatidylethanol (PEth) outcome: protocol for a systematic revie...
Jeremy C Kane, Isabel Allen, Robin Fatch, Aaron Scheffler, Nneka Emenyonu, Sarah B Puryear, Priya Chirayil, Kaku So-Armah, Christopher W Kahler, Jessica F Magidson, Am...> ;BMJ Open. 2023 Jun 6
Contingency management with stepped care for unhealthy alcohol use among individuals with HIV: Protocol for a randomized controlled trial.
E Jennifer Edelman, James Dziura, Yanhong Deng, Dominick DePhilippis, Lisa M Fucito, Tekeda Ferguson, Roger Bedimo, Sheldon Brown, Vincent C Marconi, Matthew Bidwell G...> ;Contemporary Clinical Trials. 2023 Aug 1
National Institute on Drug Abuse Clinical Trials Network Meeting Report: Advancing Emergency Department Initiation of Buprenorphine for Opioid Use Disorder.
Ethan Cowan, Jeanmarie Perrone, Steven L Bernstein, Edouard Coupet Jr, David A Fiellin, Kathryn Hawk, Andrew Herring, Kristen Huntley, Ryan McCormack, Arjun Venkatesh,...> ;Annals of Emergency Medicine. 2023 Sep 1
Perspectives on and experiences of emergency department-initiated buprenorphine among clinical pharmacists: A multi-site qualitative study.
Marissa Justen, E Jennifer Edelman, Marek Chawarski, Edouard Coupet Jr, Ethan Cowan, Michael Lyons, Patricia Owens, Shara Martel, Lynne Richardson, Richard Rothman, La...> ;Journal of Substance Use and Addiction Treatment. 2023 Dec 1
2 citations
Implementing Programs to Initiate Buprenorphine for Opioid Use Disorder Treatment in High-Need, Low-Resource Emergency Departments: A Nonrandomized Controlled Trial.
Ryan P McCormack, John Rotrosen, Phoebe Gauthier, Gail D'Onofrio, David A Fiellin, Lisa A Marsch, Patricia Novo, David Liu, E Jennifer Edelman, Sarah Farkas, Abigail G...> ;Annals of Emergency Medicine. 2023 Sep 1
2 citations
Perspectives of Clinicians and Staff at Community-Based Opioid Use Disorder Treatment Settings on Linkages With Emergency Department-Initiated Buprenorphine Programs.
Kimberly L Sue, Marek Chawarski, Leslie Curry, Ryan McNeil, Edouard Coupet Jr, Robert P Schwartz, Christine Wilder, Judith I Tsui, Kathryn F Hawk, Gail D'Onofrio, Patr...> ;JAMA Network Open. 2023 May 1
13 citations
Implementation Facilitation to Promote Emergency Department-Initiated Buprenorphine for Opioid Use Disorder.
Gail D'Onofrio, E Jennifer Edelman, Kathryn F Hawk, Marek C Chawarski, Michael V Pantalon, Patricia H Owens, Shara H Martel, Richard Rothman, Mustapha Saheed, Robert P...> ;JAMA Network Open. 2023 Apr 3
13 citations
Incidence of Precipitated Withdrawal During a Multisite Emergency Department-Initiated Buprenorphine Clinical Trial in the Era of Fentanyl.
Gail D'Onofrio, Kathryn F Hawk, Jeanmarie Perrone, Sharon L Walsh, Michelle R Lofwall, David A Fiellin, Andrew Herring> ;JAMA Network Open. 2023 Mar 1
1 citations
Concordance between controlled substance receipt and post-mortem toxicology in opioid-detected overdose deaths: A statewide analysis.
Benjamin A Howell, Anne C Black, Lauretta E Grau, Hsiu-Ju Lin, Christina Greene, Hana Lee, Robert Heimer, Kathryn E Hawk, Gail D'Onofrio, David A Fiellin, William C Be...> ;Drug and Alcohol Dependence. 2023 Mar 1
Computational phenotypes for patients with opioid-related disorders presenting to the emergency department.
R Andrew Taylor, Wade Schulz, Kevin Lopez, Patrick Young, Sameer Pandya, Andreas Coppi, David Chartash, David Fiellin, Gail D'Onofrio, Gilson, A., Gilson, A., Aidan Gi...> ;Plos One. 2023 Jan 1
1 citations
Pilot Trial of a Smartphone-Based Intervention to Reduce Alcohol Consumption among Veterans with HIV.
Taylor, E., Patel, D., Marconi, V., Whitmire, A., Hansen, N., Kershaw, T., Lauckner, C., Fiellin, D.> ;Military Behavioral Health. 2023 Jan 1
5 citations
Association Between Alcohol Use Disorder and Receipt of Direct-Acting Antiviral Hepatitis C Virus Treatment.
Lamia Y Haque, David A Fiellin, Janet P Tate, Denise Esserman, Debika Bhattacharya, Adeel A Butt, Stephen Crystal, E Jennifer Edelman, Adam J Gordon, Joseph K Lim, Jea...> ;JAMA Network Open. 2022 Dec 1
Outcomes of Patients with Opioid-Related Diagnoses in Acute Coronary Syndrome: a National Inpatient Sample-Based Analysis.
Yeunjung Kim, Justin M Pacor, Albert Do, Joseph Brennan, David A Fiellin, E Jennifer Edelman> ;Journal of General Internal Medicine. 2023 Feb 1
1 citations
Association of topiramate prescribed for any indication with reduced alcohol consumption in electronic health record data.
Henry R Kranzler, Shirley H Leong, Michelle Naps, Emily E Hartwell, David A Fiellin, Christopher T Rentsch> ;Addiction. 2022 Nov 1
5 citations
Effect of Implementation Facilitation to Promote Adoption of Medications for Addiction Treatment in US HIV Clinics: A Randomized Clinical Trial.
E Jennifer Edelman, Geliang Gan, James Dziura, Denise Esserman, Elizabeth Porter, William C Becker, Philip A Chan, Deborah H Cornman, Christian D Helfrich, Jesse Reyno...> ;JAMA Network Open. 2022 Oct 3
1 citations
Buprenorphine Initiation in the Era of High-potency Synthetic Opioids: A Call for Community-based Participatory Research to Help Learning Health Systems Provide Precis...
David A Fiellin> ;Journal of Addiction Medicine. 2022 Sep 27
8 citations
Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies.
Mehdi Farokhnia, Christopher T Rentsch, Vicky Chuong, M Adrienne McGinn, Sophie K Elvig, Eliza A Douglass, Luis A Gonzalez, Jenna E Sanfilippo, Renata C N Marchette, B...> ;Molecular Psychiatry. 2022 Nov 1
6 citations
The opioid use disorder core outcomes set (OUD-COS) for treatment research: findings from a Delphi consensus study.
Karnik, N., Marsden, J., McCluskey, C., Boley, R., Bradley, K., Campbell, C., Curtis, M., Fiellin, D., Ghitza, U., Hefner, K., Hser, Y., McHugh, R., McPherson, S., Moo...> ;Addiction. 2022 Sep 1
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Journal Articles

Racial Disparities in Discontinuation of Long-Term Opioid Therapy Following Illicit Drug Use Among Black and White Patients
David A Fiellin, William C Becker, Drug and Alcohol Dependence
Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial
Stephen R Holt, Michael Virata, David A Fiellin, E Jennifer Edelman, Lynn E Fiellin, AIDS and Behavior
Level of Alcohol Use Associated with HIV Care Continuum Targets in a National U.S. Sample of Persons Living with HIV Receiving Healthcare
E Jennifer Edelman, Derek D Satre, David A Fiellin, Adam J Gordon, Katharine A Bradley, AIDS and Behavior
AUDIT‐C and ICD Codes as Phenotypes for Harmful Alcohol Use: Association with ADH1B Polymorphisms in Two U.S. Populations
David A Fiellin, William C Becker, Joel Gelernter, Henry R Kranzler, Ning Sun, John Concato, Addiction
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Authored Content

Toward Better Stewardship: Gaining Control over Controlled SubstancesMay 2018
Toward Better Stewardship: Gaining Control over Controlled SubstancesMay 2018

Press Mentions

More Doctors Can Now Prescribe a Key Opioid Treatment. Will It Help?March 3rd, 2023
Amid Fentanyl Crisis, First-of-Its-Kind Study to Evaluate Expanded Methadone AccessFebruary 24th, 2023
Fentanyl Isn’t Just Causing Overdoses. It’s Making It Harder to Start Addiction TreatmentNovember 16th, 2022
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Grant Support

Integrated Stepped Care For Unhealthy Alcohol Use In HIVNational Institute On Alcohol Abuse And Alcoholism2011
Models Of Sbirt For Opioid Dependent Patients In The Emergency DepartmentNational Institute On Drug Abuse2008–2011
Buprenorphine Maintenance Vs. Detoxification In Prescription Opioid DependenceNational Institute On Drug Abuse2007–2011
Counseling For Primary Care Office-Based BuprenorphineNational Institute On Drug Abuse2005–2009