DavidJFlintMD

PubMed

• 69 citations
  IGFBP5 induces cell adhesion, increases cell survival and inhibits cell migration in MCF-7 human breast cancer cells.
  Angara Sureshbabu, Hiroshi Okajima, Daisuke Yamanaka, Elizabeth Tonner, Surya Shastri, Joanna Maycock, Malgorzata Szymanowska, John H. Shand, Shinichiro Takahashi, Jam...> ;Journal of Cell Science. 2012 Apr 1
• 36 citations
  The connexin mimetic peptide Gap27 increases human dermal fibroblast migration in hyperglycemic and hyperinsulinemic conditions in vitro.
  Catherine Wright, Simone Pollok, David J. Flint, Johanna M. Brandner, Patricia Martin> ;Journal of Cellular Physiology. 2012 Jan 1
• 14 citations
  Insulin-like growth factor binding proteins and mammary gland development.
  Angara Sureshbabu, Elizabeth Tonner, David J. Flint> ;The International Journal of Developmental Biology. 2011 Nov 29
• 55 citations
  Evaluation of anionic half generation 3.5-6.5 poly(amidoamine) dendrimers as delivery vehicles for the active component of the anticancer drug cisplatin.
  Gordon J Kirkpatrick, Jane A. Plumb, Oliver B. Sutcliffe, David J. Flint, Nial J. Wheate> ;Journal of Inorganic Biochemistry. 2011 Sep 1
• 5 citations
  Cellular Trans-Differentiation and Morphogenesis Toward the Lymphatic Lineage in Regenerative Medicine
  Filip Laco, Mary Grant, David J. Flint, Richard A. Black> ;Stem Cells and Development. 2011 Feb 1
• 22 citations
  Relative Roles of TGF-β and IGFBP-5 in Idiopathic Pulmonary Fibrosis
  Angara Sureshbabu, Elizabeth Tonner, Gordon J. Allan, David J. Flint> ;Pulmonary Medicine. 2011 Jan 26
• 424 citations
  Gold Nanoparticles for the Improved Anticancer Drug Delivery of the Active Component of Oxaliplatin
  Sarah Brown, Paola Nativo, Jo-Ann Smith, David Stirling, Paul R. Edwards, Balaji Venugopal, David J. Flint, Jane A. Plumb, Duncan Graham, Nial J. Wheate> ;Journal of the American Chemical Society. 2010 Apr 7
• 9 citations
  Establishment of a Mammary Stromal Fibroblastic Cell Line for In Vitro Studies in Mice of Mammary Adipocyte Differentiation
  Hajime Nakatani, Naohito Aoki, Tetsuya Okajima, Daita Nadano, David J. Flint, Tsukasa Matsuda> ;Biology of Reproduction. 2010 Jan 1
• 23 citations
  IGFBP-5 induces epithelial and fibroblast responses consistent with the fibrotic response
  Angara Sureshbabu, Hiroshi Okajima, Daisuke Yamanaka, Surya Shastri, Elizabeth Tonner, Colin Rae, Malgorzata Szymanowska, John H. Shand, Shinichiro Takahashi, James Be...> ;Biochemical Society Transactions. 2009 Aug 1
• 13 citations
  IGFBP-3 and IGFBP-5 associate with the cell binding domain (CBD) of fibronectin.
  James Beattie, Michaela Kreiner, Gordon J. Allan, David J. Flint, Diana Domingues, Christopher F. van der Walle> ;Biochemical and Biophysical Research Communications. 2009 Apr 17
• 3 citations
  Antibodies as molecular mimics of biomolecules: roles in understanding physiological functions and mechanisms
  Rodney A. Hill, David J. Flint, Jennifer M. Pell> ;Advances in Physiology Education. 2008 Dec 1
• 21 citations
  Role of Insulin-Like Growth Factor Binding Proteins in Mammary Gland Development
  David J. Flint, Elizabeth Tonner, James Beattie, Gordon J. Allan> ;Journal of Mammary Gland Biology and Neoplasia. 2008 Nov 8
• 36 citations
  Epithelial injury induces an innate repair mechanism linked to cellular senescence and fibrosis involving IGF-binding protein-5.
  Gordon J. Allan, James Beattie, David J. Flint> ;The Journal of Endocrinology. 2008 Nov 1
• 22 citations
  Molecular interactions in the insulin-like growth factor (IGF) axis: a surface plasmon resonance (SPR) based biosensor study
  James Beattie, Kirsten Phillips, John H. Shand, Malgorzata Szymanowska, David J. Flint, Gordon J. Allan> ;Molecular and Cellular Biochemistry. 2007 Sep 25
• 37 citations
  Developmental aspects of adipose tissue in GH receptor and prolactin receptor gene disrupted mice: site-specific effects upon proliferation, differentiation and hormon...
  David J. Flint, Nadine Binart, Stephanie Boumard, John J. Kopchick, Paul A Kelly> ;The Journal of Endocrinology. 2006 Oct 1
• 16 citations
  Prolactin inhibits cell loss and decreases matrix metalloproteinase expression in the involuting mouse mammary gland but fails to prevent cell loss in the mammary glan...
  David J. Flint, Marion Boutinaud, Christopher Bruce Alexander Whitelaw, Gordon J. Allan, Andreas F. Kolb> ;Journal of Molecular Endocrinology. 2006 Jun 1
• 29 citations
  Insulin‐like growth factor binding protein (IGFBP)‐5 is upregulated during both differentiation and apoptosis in primary cultures of mouse mammary epithelial cells
  Jennifer D. Lochrie, Kirsten Phillips, Elizabeth Tonner, David J. Flint, Gordon J. Allan, Nicholas C. Price, James Beattie> ;Journal of Cellular Physiology. 2006 May 1
• 30 citations
  Insulin-like Growth Factor-binding Protein-5 Activates Plasminogen by Interaction with Tissue Plasminogen Activator, Independently of Its Ability to Bind to Plasminoge...
  Alice M. Sorrell, John H. Shand, Elizabeth Tonner, Matteo Gamberoni, Pier Attilio Accorsi, James Beattie, Gordon J. Allan, David J. Flint> ;The Journal of Biological Chemistry. 2006 Apr 21
• 173 citations
  Insulin-like growth factor-binding protein-5 (IGFBP-5): a critical member of the IGF axis
  James Beattie, Gordon J. Allan, Jennifer D. Lochrie, David J. Flint> ;The Biochemical Journal. 2006 Apr 1
• 16 citations
  Cumulative mutagenesis of the basic residues in the 201-218 region of insulin-like growth factor (IGF)-binding protein-5 results in progressive loss of both IGF-I bind...
  Gordon J. Allan, Elizabeth Tonner, Malgorzata Szymanowska, John H. Shand, Sharon M. Kelly, Kirsten Phillips, Roger A. Clegg, Iain F. Gow, James Beattie, David J. Flint> ;Endocrinology. 2006 Jan 1
• 16 citations
  Regulation of genes encoding proteolytic enzymes during mammary gland development.
  David A. Sorrell, Malgorzata Szymanowska, Marion Boutinaud, Claire Robinson, Richard W. E. Clarkson, Torsten Stein, David J. Flint, Andreas F. Kolb> ;The Journal of Dairy Research. 2005 Nov 1
• 33 citations
  Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland
  David J. Flint, Marion Boutinaud, Elizabeth Tonner, C. J. Wilde, Walter L. Hurley, Pier Attilio Accorsi, Andreas F. Kolb, C B A Whitelaw, James Beattie, Gordon J. Allan> ;Domestic Animal Endocrinology. 2005 Aug 1
• 69 citations
  Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland
  David J. Flint, Maureen T. Travers, Michael C. Barber, Nadine Binart, Paul A.T. Kelly> ;American Journal of Physiology. Endocrinology and Metabolism. 2005 Jun 1
• 25 citations
  Molecular recognition characteristics in the insulin-like growth factor (IGF)-insulin-like growth factor binding protein -3/5 (IGFBP-3/5) heparin axis
  James Beattie, Kirsten Phillips, John H. Shand, Malgorzata Szymanowska, David J. Flint, Gordon J. Allan> ;Journal of Molecular Endocrinology. 2005 Feb 1
• 36 citations
  The role of IGFBP-5 in mammary gland development and involution.
  Gordon J. Allan, James Beattie, David J. Flint> ;Domestic Animal Endocrinology. 2004 Oct 1
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