DavidJonathanGlassMD

PubMed

• 79 citations
  Activin type II receptor signaling in cardiac aging and heart failure.
  Jason D. Roh, Ryan Hobson, Vinita Chaudhari, Pablo A. Quintero, Ashish Yeri, Mark D. Benson, Chunyang Xiao, Daniel A. Zlotoff, Vassilios J. Bezzerides, Nicholas E. Hou...> ;Science Translational Medicine. 2019 Mar 6
• Safety, Tolerability, and Preliminary Efficacy of an IGF-1 Mimetic in Patients with Spinal and Bulbar Muscular Atrophy: A Randomised, Placebo-Controlled Trial
  Tahseen Mozaffar, Kenneth H Fischbeck, Christopher Grunseich, Matthew N Meriggioli, John T Kissel, David J Glass> ;The Lancet.
• 262 citations
  TORC1 inhibition enhances immune function and reduces infections in the elderly.
  Joan Mannick, Melody Morris, Hans-Ulrich P. Hockey, Guglielmo Roma, Martin Beibel, Kenneth Kulmatycki, Mollie Watkins, Tea Shavlakadze, Weihua Zhou, Dean Quinn, David ...> ;Science Translational Medicine. 2018 Jul 11
• 38 citations
  Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology.
  Tea Shavlakadze, Jiang Zhu, Sharon X. Wang, Weihua Zhou, Bret Morin, Marc A. Egerman, Lin Fan, Yanqun Wang, Oleg Iartchouk, Angelika Meyer, Reginald Valdez, Joan Manni...> ;The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2018 Jun 14
• Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15.
  Jones, J. E.,Cadena, S. M.,Gong, C.,Wang, X.,Chen, Z.,Wang, S. X.,Vickers, C.,Chen, H.,Lach-Trifilieff, E.,Hadcock, J. R.,Glass, D. J.> ;Cell Rep. 2018 Feb 10
• 45 citations
  Alterations in the in vitro and in vivo regulation of muscle regeneration in healthy ageing and the influence of sarcopenia
  Joanna Brzeszczynska, Angelika Meyer, Robin A. McGregor, Alain Schilb, Simone Degen, Valentina Tadini, Neil Johns, Ramon C. J. Langen, Annemie M. W. J. Schols, David J...> ;Journal of Cachexia, Sarcopenia and Muscle. 2018 Feb 1
• 43 citations
  ATP Citrate Lyase Regulates Myofiber Differentiation and Increases Regeneration by Altering Histone Acetylation.
  Suman K. Das, Frederic Morvan, Giulio Morozzi, Benjamin Jourde, Giulia Minetti, Peter Kahle, Helene Rivet, Pascale Brebbia, Gauthier Toussaint, David J. Glass, Mara Fo...> ;Cell Reports. 2017 Dec 12
• 41 citations
  Blockade of Metallothioneins 1 and 2 Increases Skeletal Muscle Mass and Strength
  Serge Summermatter, Anais Bouzan, Eliane Pierrel, Stefan Melly, Daniela Stauffer, Sabine Gutzwiller, Erin Nolin, Christina Dornelas, Christy Fryer, Juliet Leighton-Dav...> ;Molecular and Cellular Biology. 2017 Feb 15
• 17 citations
  Elevated GDF11 Is a Risk Factor for Age-Related Frailty and Disease in Humans.
  David J. Glass> ;Cell Metabolism. 2016 Jul 12
• 37 citations
  Muscle RING‐finger 2 and 3 maintain striated‐muscle structure and function
  Dörte Lodka, Aanchal Pahuja, Cornelia Geers-Knörr, Renate J. Scheibe, Marcel Nowak, Jida Hamati, Clemens Köhncke, Bettina Purfürst, Tamara Kanashova, Sibylle Schmidt, ...> ;Journal of Cachexia, Sarcopenia and Muscle. 2016 May 1
• 14 citations
  Α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction.
  Jacinthe Gingras, Marta Gawor, Krzysztof M. Bernadzki, R. Mark Grady, Peter T. Hallock, David J. Glass, Joshua R. Sanes, Tomasz J. Proszynski> ;Journal of Cell Science. 2016 Mar 1
• 22 citations
  Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation
  Peter T. Hallock, Sherry Chin, Steven Blais, Thomas A. Neubert, David J. Glass> ;Molecular and Cellular Biology. 2015 Nov 2
• 39 citations
  The ubiquitin ligase MuRF1 regulates PPARα activity in the heart by enhancing nuclear export via monoubiquitination.
  Jessica E. Rodríguez, Jie Ying Liao, Jun He, Jonathan C. Schisler, Christopher B. Newgard, Doreen Drujan, David J. Glass, C. Brandon Frederick, Bryan C. Yoder, David S...> ;Molecular and Cellular Endocrinology. 2015 Sep 15
• 204 citations
  A Long Non-coding RNA, LncMyoD, Regulates Skeletal Muscle Differentiation by Blocking IMP2-Mediated mRNA Translation
  Chenguang Gong, Zhizhong Li, Krishnan Ramanujan, Ieuan Clay, Yunyu Zhang, Sophie Lemire-Brachat, David J. Glass> ;Developmental Cell. 2015 Jul 27
• 391 citations
  GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.
  Marc A. Egerman, Samuel M. Cadena, Jason A. Gilbert, Angelika Meyer, Hallie N. Nelson, Susanne E. Swalley, Carolyn Mallozzi, Carsten Jacobi, Lori L. Jennings, Ieuan Cl...> ;Cell Metabolism. 2015 Jul 7
• 61 citations
  ATP Citrate Lyase Improves Mitochondrial Function in Skeletal Muscle
  Suman K. Das, Frederic Morvan, Benjamin Jourde, Viktor Meier, Peter Kahle, Pascale Brebbia, Gauthier Toussaint, David J. Glass, Mara Fornaro> ;Cell Metabolism. 2015 Jun 2
• 467 citations
  mTOR inhibition improves immune function in the elderly
  Joan Mannick, Giuseppe Del Giudice, Maria Lattanzi, Nicholas Valiante, Jens Praestgaard, Baisong Huang, Michael A. Lonetto, Holden T. Maecker, John S. Kovarik, Simon C...> ;Science Translational Medicine. 2014 Dec 24
• 139 citations
  Treatment of sporadic inclusion body myositis with bimagrumab
  Anthony A. Amato, Kumaraswamy Sivakumar, Namita Goyal, William S. David, Mohammad Salajegheh, Jens Praestgaard, Estelle Lach-Trifilieff, Anne-Ulrike Trendelenburg, Did...> ;Neurology. 2014 Dec 9
• 75 citations
  G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy.
  James P. White, Christiane D. Wrann, Rajesh R. Rao, Sreekumaran K Nair, Mark P. Jedrychowski, Jae-Sung You, Vicente Martínez-Redondo, Steven P. Gygi, Jorge L. Ruas, Tr...> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Nov 4
• 19 citations
  MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart☆
  Kedryn K. Baskin, Meredith R. Rodriguez, Seema Kansara, Wenhao Chen, Sylvia Carranza, O. Howard Frazier, David J. Glass, Heinrich Taegtmeyer> ;Journal of Molecular and Cellular Cardiology. 2014 Jul 1
• 9 citations
  Deletion of atrophy enhancing genes fails to ameliorate the phenotype in a mouse model of spinal muscular atrophy.
  Chitra C. Iyer, Vicki L. McGovern, Dawnne O.Neal Wise, David J. Glass, Arthur H.M. Burghes> ;Neuromuscular Disorders. 2014 May 1
• 2 citations
  NIH grants: Focus on questions, not hypotheses
  David J. Glass> ;Nature. 2014 Mar 20
• 206 citations
  An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy
  Estelle Lach-Trifilieff, Giulia Minetti, Kelly-Ann Sheppard, Chikwendu Ibebunjo, Jerome N. Feige, Steffen Hartmann, Sophie Brachat, Helene Rivet, Claudia Koelbing, Fre...> ;Molecular and Cellular Biology. 2014 Feb 15
• 36 citations
  Gαi2 signaling is required for skeletal muscle growth, regeneration, and satellite cell proliferation and differentiation.
  Giulia Minetti, Jerome N. Feige, Florian Bombard, Annabelle Heier, Fredric Morvan, Bernd Nürnberg, Veronika Leiss, Lutz Birnbaumer, David J. Glass, Mara Fornaro> ;Molecular and Cellular Biology. 2014 Feb 15
• 1 citations
  Skeletal muscle's 3rd year anniversary.
  David J. Glass, Kevin P. Campbell, Michael A. Rudnicki> ;Skeletal Muscle. 2014 Jan 24
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Journal Articles

• Signaling pathways controlling skeletal muscle mass.  
  Egerman MA, Glass DJ, Crit Rev Biochem Mol Biol., 11/18/2013