DavidGozalMDMBA, DSc(Hon)

PubMed

• Recovery Mimicking "Ideal" CPAP Adherence Does Not Improve Wakefulness or Cognition in Chronic Murine Models of OSA: Effect of Wake-Promoting Agents.
  Mohammad Badran, Clementine Puech, Max B Barrow, Alexandra R Runion, David Gozal> ;Archivos De Bronconeumologia. 2023 Dec 1
• Do Inhaled Corticosteroids Increase the Risk of Obstructive Sleep Apnea?
  David Gozal, Jose Daniel Gomez-Olivas, Miguel Ángel Martínez-García, Grace Oscullo> ;Archivos De Bronconeumologia. 2023 Sep 1
• Exploring the bidirectional relationship between asthma and obstructive sleep apnea in Brazilian pediatric patients: one more piece to the Puzzle.
  Luana Nosetti, David Gozal> ;Jornal De Pediatria. 2023 May 27
• 2 citations
  Effect of Hypertonic Saline on Lung Function as Add-on Treatment in People With Cystic Fibrosis Receiving Dornase Alfa: A Cystic Fibrosis Foundation Patient Registry A...
  James Acton, Connie Fenton, Leila Kheirandish-Gozal, Zarah Ner, Rebekah Nevel, David Gozal, Adrienne Ohler, Kaditis, A.> ;Chest. 2023 Oct 1
• 4 citations
  Solriamfetol enhances wakefulness and improves cognition and anxiety in a murine model of OSA.
  Mohammad Badran, Clementine Puech, Max B Barrow, Alexandra R Runion, David Gozal> ;Sleep Medicine. 2023 Jul 1
• 3 citations
  Biomarkers of gut barrier dysfunction in obstructive sleep apnea: A systematic review and meta-analysis.
  Saif Mashaqi, Pooja Rangan, Ahlam A Saleh, Ivo Abraham, David Gozal, Stuart F Quan, Sairam Parthasarathy> ;Sleep Medicine Reviews. 2023 Jun 1
• 8 citations
  Potential Pathophysiological Pathways in the Complex Relationships between OSA and Cancer.
  Manuel Sánchez-de-la-Torre, Carolina Cubillos, Olivia J Veatch, Francisco Garcia-Rio, David Gozal, Miguel Angel Martinez-Garcia> ;Cancers. 2023 Feb 7
• 1 citations
  Nintedanib in chILD: a small step, yes… but at least a step forward in a marathon!
  David Gozal, Martin Kolb> ;The European Respiratory Journal. 2023 Feb 1
• Cardiovascular Disease in Obstructive Sleep Apnea: Putative Contributions of Mineralocorticoid Receptors.
  Mohammad Badran, Shawn B Bender, David Gozal> ;International Journal of Molecular Sciences. 2023 Jan 23
• 1 citations
  The sleep and wake electroencephalogram over the lifespan.
  Haoqi Sun, Elissa Ye, Luis Paixao, Wolfgang Ganglberger, Catherine J Chu, Can Zhang, Jonathan Rosand, Emmanuel Mignot, Sydney S Cash, David Gozal, Robert J Thomas, M B...> ;Neurobiology of Aging. 2023 Apr 1
• 7 citations
  Pediatric sleep apnea: Characterization of apneic events and sleep stages using heart rate variability.
  Adrián Martín-Montero, Pablo Armañac-Julián, Eduardo Gil, Leila Kheirandish-Gozal, Daniel Álvarez, Jesús Lázaro, Raquel Bailón, David Gozal, Pablo Laguna, Roberto Horn...> ;Computers in Biology and Medicine. 2023 Mar 1
• 2 citations
  Catecholaminergic axon innervation and morphology in flat-mounts of atria and ventricles of mice.
  Ariege Bizanti, Yuanyuan Zhang, Scott W Harden, Jin Chen, Donald B Hoover, David Gozal, Kalyanam Shivkumar, Zixi Jack Cheng> ;The Journal of Comparative Neurology. 2023 Apr 1
• 1 citations
  Screen use, sleep duration, daytime somnolence, and academic failure in school-aged adolescents.
  Daniel Pérez-Chada, Sergio Arias Bioch, Daniel Schönfeld, David Gozal, Santiago Perez-Lloret> ;Plos One. 2023 Jan 1
• 6 citations
  Chronic Intermittent Hypoxia during Sleep Causes Browning of Interscapular Adipose Tissue Accompanied by Local Insulin Resistance in Mice.
  Tehila Dahan, Shahd Nassar, Olga Yajuk, Eliana Steinberg, Ofra Benny, Nathalie Abudi, Inbar Plaschkes, Hadar Benyamini, David Gozal, Rinat Abramovitch, Alex Gileles-Hi...> ;International Journal of Molecular Sciences. 2022 Dec 7
• Sleep irregularity and duration in teenagers: a complex constellation of cause, consequence, both, and interdependencies.
  Daniel Perez-Chada, David Gozal> ;Sleep. 2023 Feb 8
• Prevalence and risk factors of sleep problems in Bangladesh during the COVID-19 pandemic: a systematic review and meta-analysis.
  Mohammed A Mamun, Firoj Al-Mamun, Ismail Hosen, Mark Mohan Kaggwa, Md Tajuddin Sikder, Mohammad Muhit, David Gozal> ;Sleep Epidemiology. 2022 Dec 1
• Validation of a predictive model for obstructive sleep apnea in people with Down syndrome.
  Brian G Skotko, Alexandra Garza Flores, Ibrahim Elsharkawi, Vasiliki Patsiogiannis, Mary Ellen McDonough, Damiano Verda, Marco Muselli, Roberto Hornero, David Gozal, E...> ;American Journal of Medical Genetics. Part A. 2023 Feb 1
• 1 citations
  Validity and reliability of the Japanese version of the severity hierarchy score for pediatric obstructive sleep apnea screening.
  Qinye Zhu, Hiroo Wada, Keisike Onuki, Takayuki Kitazawa, Ritsuko Furuya, Mariko Miyakawa, Setsuko Sato, Naohiro Yonemoto, Yuito Ueda, Hiroshi Nakano, David Gozal, Take...> ;Sleep Medicine. 2023 Jan 1
• 8 citations
  Experimental Models to Study End-Organ Morbidity in Sleep Apnea: Lessons Learned and Future Directions.
  Ramon Farré, Isaac Almendros, Miguel-Ángel Martínez-García, David Gozal> ;International Journal of Molecular Sciences. 2022 Nov 20
• 4 citations
  Single-cell RNA-seq uncovers cellular heterogeneity and provides a signature for paediatric sleep apnoea.
  Rene Cortese, Taylor S Adams, Kylie H Cataldo, Justin Hummel, Naftali Kaminski, Leila Kheirandish-Gozal, David Gozal> ;The European Respiratory Journal. 2023 Feb 1
• 7 citations
  Explicit memory, anxiety and depressive like behavior in mice exposed to chronic intermittent hypoxia, sleep fragmentation, or both during the daylight period.
  Clementine Puech, Mohammad Badran, Alexandra R Runion, Max B Barrow, Zhuanhong Qiao, Abdelnaby Khalyfa, David Gozal> ;Neurobiology of Sleep and Circadian Rhythms. 2022 Nov 1
• Spatial association ofwith dengue fever hotspots in an endemic region.
  Mohiuddin Sharif, Md Abdullah Saeed Khan, Mohammad Jahid Hasan, Tanzin Naher, Sujan Rudra, Jannatul Fardous, David Gozal, Md Khalilur Rahman, Mohammad Robed Amin> ;Heliyon. 2022 Nov 1
• 5 citations
  Obstructive sleep apnoea is related to melanoma aggressiveness through paraspeckle protein-1 upregulation.
  Carolina Cubillos-Zapata, Miguel Ángel Martínez-García, Elena Díaz-García, Sara García-Tovar, Francisco Campos-Rodríguez, Manuel Sánchez-de-la-Torre, Eduardo Nagore, A...> ;The European Respiratory Journal. 2023 Feb 1
• Cluster Analysis of Home Polygraphic Recordings in Symptomatic Habitually-Snoring Children: A Precision Medicine Perspective.
  Marco Zaffanello, Angelo Pietrobelli, David Gozal, Luana Nosetti, Stefania La Grutta, Giovanna Cilluffo, Giuliana Ferrante, Michele Piazza, Giorgio Piacentini> ;Journal of Clinical Medicine. 2022 Oct 9
• Acute Poisoning in Bangladesh: A Systematic Narrative Review.
  Mohammad Jahid Hasan, Md Kamrul Hassan, Zuhayer Ahmed, Md Abdullah Saeed Khan, Jannatul Fardous, Tamanna Tabasssum, Fazle Rabbi Chowdhury, David Gozal, Mohammad Robed ...> ;Asia-Pacific Journal of Public Health. 2022 Nov 1
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Journal Articles

• Sleep-Disordered Breathing, Circulating Exosomes, and Insulin Sensitivity in Adipocytes  
  David Gozal, MD, Nature
• Acetylsalicylic Acid Prevents Intermittent Hypoxia-Induced Vascular Remodeling in a Murine Model of Sleep Apnea  
  David Gozal, MD, Frontiers in Neurology
• Sleep fragmentation promotes NADPH oxidase 2-mediated adipose tissue inflammation leading to insulin resistance in mice  
  Zhang SX, Khalyfa A, Wang Y, Carreras A, Hakim F, Neel BA, Brady M, Qiao Z, Hirotsu C, Gozal D, International Journal of Obesity, 1/1/2014
• Chronic fragmented sleep promotes obesity in mice  
  Wang Y, Carreras A, Lee SH, Hakim F, Zhang SXL, Nair D, Ye H, Gozal D, Obesity, 1/1/2014
• Substance P and neurokinin 1 receptors as potential therapeutic targets in children with OSA  
  Gozal D, Kim J, Bhattacharjee R, Goldman JL, Kheirandish-Gozal L, Chest, 1/1/2014
• Vitamin D levels and pediatric obstructive sleep apnea  
  Kheirandish-Gozal L, Peris E, Gozal D, Sleep Medicine, 1/1/2014
• Fragmented sleep accelerates tumor growth and progression through recruitment of tumor-associated macrophages and TLR4 signaling  
  Hakim F, Wang Y, Zhang SX, Zheng J, Yolcu E, Carreras A, Khalyfa A, Shirwan H, Almendros I, Gozal D, Cancer Res, 1/1/2014
• Contextualized urinary biomarker analysis facilitates diagnosis of pediatric obstructive sleep apnea  
  Becker L, Kheirandish-Gozal L, Peris E, Schoenfelt KQ, Gozal D, Sleep Medicine, 1/1/2014
• Intermittent hypoxia-induced changes in tumor-associated macrophages and tumor malignancy in murine sleep apnea model  
  Almendros I, Wang Y, Becker L, Lennon F, Zheng J, Coats B, Schoenfelt KS, Carreras A, Hakim F, Zhang SX, Farre R, Gozal D, Am J. Resp Crit Care Med, 1/1/2014
• The promise of translational and personalized approaches for paediatric obstructive sleep apnoea: An “Omics” perspective  
  Tan H, Kheirandish-Gozal L, Gozal D, Thorax, 1/1/2014
• Nitric oxide production by monocytes in children with OSA and endothelial dysfunction  
  Kheirandish-Gozal L, Wang Y, Duggan RC, Harshan Vardhan S, Tan HL, Molero Ramirez H, Khalyfa A, Bhattacharjee R, Bandla HP, Gozal D, Clin Sci (Lond), 1/1/2014
• Sleep apnea awakes cancer: a unifying immunological hypothesis  
  Gozal D, Almendros I, Hakim F, OncoImmunol, 1/1/2014
• Estimating child sleep from parent report of time in bed: Development and evaluation of adjustment approaches  
  Nelson TD, Lundhal A, Molfese DL, Waford R, Roman A, Gozal D, Molfese VJ, Rue A, Ferguson M, J. Pediatr. Psychol, 1/1/2014
• Sleep disordered breathing in children with craniosynostosis  
  Alsaadi MM, Iqbal SM, Elgamal EA, Salih MA, Gozal D, Sleep & Breath, 1/1/2013
• TREM 1 and Pentraxin 3 plasma levels and their association with obstructive sleep apnea, obesity, and endothelial function in children  
  Kim J, Gozal D, Bhattacharjee R, Kheirandish-Gozal L, Sleep, 1/1/2013
• Circulating adropin levels in pediatric OSA: Potential relevance to endothelial function  
  Gozal D, Kheirandish-Gozal L, Bhattacharjee R, Molero Ramirez H, Tan HL, Bandla HPR, J Pediatr, 1/1/2013
• C-Reactive Protein and obstructive sleep apnea syndrome in children  
  Gozal D, Kheirandish-Gozal L, Bhattacharjee R, Kim J, Frontiers in Bioscience, 1/1/2012
• Algorithm for the diagnosis and management of pediatric OSA: A proposal  
  Kaditis AG, Kheirandish-Gozal L, Gozal D, Sleep Medicine, 1/1/2012
• A mediation model linking body weight, cognition, and sleep disordered breathing  
  Spruyt K, Gozal D, Am J. Resp Crit Care Med, 1/1/2012
• Pathological consequences of intermittent hypoxia in the central nervous system  
  Zhang SXL, Wang Y, Gozal D, Comprehensive Physiol, 1/1/2012
• Sympathetic and catecholaminergic alterations in pediatric sleep disorders  
  Hakim F, Gozal D, Kheirandish-Gozal L, Front Neurol, 1/1/2012
• Response to letter on “Adenotonsillectomy outcomes in treatment of obstructive sleep apnea in children: A multicenter retrospective study”  
  Bhattacharjee R, Gozal D, Am. J. Respir. Crit. Care Med, 1/1/2012
• Obstructive sleep apnea in poorly controlled asthmatic children: effect of adenotonsillectomy  
  Kheirandish-Gozal L, Dayyat EA, Eid NS, Morton RL, Gozal D, Pediatr. Pulmonol, 9/1/2011
• Pediatric sleep questionnaires as diagnostic or epidemiological tools: a review of currently available instruments  
  Spruyt K, Gozal D, Sleep Med Rev, 1/1/2011
• Fatty-acid binding protein 4 gene polymorphisms and plasma levels in children with obstructive sleep apnea  
  Bhushan B, Khalyfa A, Spruyt K, Kheirandish-Gozal L, Sans Capdevila O, Bhattacharjee R, Kim J, Keating B, Hakonarson H, Gozal D, Sleep Medicine, 1/1/2011
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Books/Book Chapters

• Physiology and Pharmacology of Cardiorespiratory Control. 
  Chapter: Children who Forget to Breathe: The Physiological Enigma of the Congenital Central Hypoventilation Syndrome. 
  Page 65 - 74Gozal DEditors: Dahan A, Teppema L, Van Beek J., Kluwer Academic Publishers, Dordrecht, The Netherlands.
• Sleep and Breathing in Children - A Developmental Approach. 
  Chapter: New Insights into Maturation of Central Components in Cardiovascular and Respiratory Control. 
  Editors: Biology in Health and Disease, Marcel Dekker, Inc., New York.Loughlin GM, Marcus CL, Carrol JL
• Animal Models of Sleep Related Breathing Disorders. 
  Chapter: Gene and protein expression and regulation in the CNS. 
  Page 109 - 179Kubin L, Czycyk-Krzeska MF, Gozal DEditors: Carley D, Radulovacki M.Lung Biology in Health and Disease, Marcel Dekker, Inc., New York
• Nelson Textbook of Pediatrics. 
  Chapter: Respiratory manifestations of neuromuscular diseases. 
  Gozal DWB Saunders, PhiladelphiaEdition 17,
• Pharmacology and Pathophysiology of the Control of Breathing. 
  Chapter: Congenital central hypoventilation syndrome: should we rename it congenital autonomopathy? 
  Gozal DEditors: Ward D, Dahan A, Teppema L.Lung Biology in Health and Disease, Marcel Dekker, Inc., New York
• Chernick-Mellins Basic Mechanisms of Pediatric Respiratory Disease. 
  Chapter: Sleep and Respiratory Control. 
  Page 412 - 430Harper RM, Gozal DEditors: Haddad GG, Abman SH, Chernick V.B.C. Decker Inc. Hamilton, Ontario, CanadaEdition 2,
• Encyclopedia of Respiratory Medicine. 
  Chapter: Inherited Myopathies 
  Page 98 - 103Gozal D, Godbart ADEditors: Geoffrey J. Laurent and Steven D. Shapiro.Elsevier Ltd
• Kendig’s Disorders of the Respiratory Tract in Children. 
  Chapter: Disorders of Breathing During Sleep. 
  Page 1046 - 1070Gozal D, Kheirandish LEditors: Chernick V, Boat T, Wilmott R, Bush A.Elsevier Ltd.
• Clinician’s Guide to Pediatric Sleep Disorders. 
  Chapter: Neurobehavioral morbidity in children with sleep-disordered breathing. 
  Gozal D, Kheirandish-Gozal LEditors: Richardson MA, Friedman NR.Informa Healthcare
• D. Molfese and V. Molfese Handbook of Developmental Neuropsychology. 
  Chapter: Sleep-disordered breathing. 
  Crabtree, VM, Gozal DLawrence Erlbaum Associates
• Sleep: A Comprehensive Handbook. 
  Chapter: Sleep and breathing during early post natal life. 
  Page 511 - 516Goldbart AD, Tauman R, Gozal DEditors: Lee-Chiong T. Wiley-Liss.Hoboken, New Jersey
• Nelson Textbook of Pediatrics. 
  Chapter: Respiratory manifestations of neuromuscular diseases. 
  Gozal D, Kheirandish LWB Saunders, Philadelphia
• Sleep and Breathing in Children - A Developmental Approach. 
  Chapter: Maturation and Plasticity of Central Components in Cardiovascular and Respiratory Control. 
  Gozal D, Harper RMEditors: Loughlin GM, Marcus CL, Carrol JL, Donnelly, D.Lung Biology in Health and Disease, Marcel Dekker, Inc., New YorkEdition 2,
• Sleep and Breathing in Children - A Developmental Approach. 
  Chapter: Metabolic Aspects of Sleep Apnea in Children. 
  Tauman R, Gozal DEditors: Loughlin GM, Marcus CL, Carrol JL, Donnelly, D.Lung Biology in Health and Disease, Marcel Dekker, Inc., New YorkEdition 2,
• Sleep Apnea: Pathogenesis,Diagnosis and Treatment. 
  Chapter: Intermittent Hypoxia and Neurocognitive Function. 
  Gozal D, Kheirandish-Gozal L, Row BWEditors: Pack AI.Lung Biology in Health and Disease, Marcel Dekker, Inc., New YorkEdition 2,
• Textbook of Pediatrics 2001. 
  Chapter: Obstructive sleep apnea. 
  Lipton AJ, Gozal Dhttp://www.emedicine.com
• The Urinary Proteome. 
  Chapter: Urinary proteins for the diagnosis of obstructive sleep apnea syndrome. 
  Snow A, Gozal D, Valdes Jr R, Jortani SEditors: Ray A.Methods in Mol Biol
• Genetic Basis for Respiratory Control Disorders. 
  Chapter: Respiratory control disorders: from genes to patients and back. 
  Gozal DEditors: Gaultier C.Springer Verlag
• Textbook of Pediatrics 2001. 
  Chapter: Ondine’s Curse. 
  Gozal Dhttp://www.emedicine.com
• Handbook of Clinical Neurology: Sleep Disorders. 
  Chapter: Sleep-associated respiratory disorders and their psycho-behavioral consequences in children. 
  Montgomery-Downs HE, Gozal DEditors: P. Montagna and S. Chokroverty., Elsevier.Handb Clin Neurol
• Encyclopedia of Neuroscience. 
  Chapter: Respiratory network responses to hypoxia. 
  Simakajornboon N, Gozal DEditors: Binder MD, Hirokawa N, Windhorst U, Hirsch MC, Springer Verlag.
• Casebook of Sleep Medicine. A Learning Companion to the International Classification of Sleep Disorders. 
  Chapter: Insomnia Due to Medical Condition. 
  Crabtree VM, Krishna J, Gozal DEditors: Winkleman JW, Henderson II JH, Kotagal S, Lee-chiong TL, Lichstein KL, Murray BJ, Schenck CH..American Academy of Sleep MedicineEdition 2,
• Rudolph’s Pediatrics. 
  Chapter: Disorders of Breathing During Sleep. 
  Gozal D, Kheirandish-Gozal LEditors: Rudolph AM, Rudolph C, First L, Lister G, Gershon AA.Edition 22,
• Ventral Brainstem Mechanisms and Control Functions. 
  Chapter: Functional assessment of the ventral medullary surface by optical imaging. 
  Page 67 - 79Gozal D, Rector DM, Harper RMEditors: Trouth CO, Millis RM, Kiwull-Schöne H, Schläfke ME, Lung Biology in Health and Disease, Marcel...
• Emedicine from WebMD. 
  Chapter: Congenital Central Hypoventilation Syndrome. 
  Chin T, Ischander MM, Gozal Dhttp://www.emedicine.com/ped/topic1645.htm
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Abstracts/Posters

• Year Book of Critical Care Medicine.
  Gozal D, Ziser A, Shupak A, Melamed Y, Accidental carbon monoxide poisoning in children: Emphasis on hyperbaric oxygen treatment
• Mosby Year Book of Pulmonary Disease.
  Gozal D, Colin AA, Jaffe M, Hochberg Z, Water, electrolyte and endocrine homeostasis on infants with bronchiolitis

Lectures

• Advances in Kids Medicine 
  The University of Chicago, Center for Continuing Medical Education, Lemont, Illinois - 11/2/2011