DavidPKelsenMD

Professor of Medicine, Cornell University-Weill Medical College

Overview of Dr. Kelsen

Dr. David Kelsen is an oncologist in New York, NY and is affiliated with multiple hospitals in the area, including Memorial Sloan-Kettering Cancer Center and Memorial Sloan Kettering Bergen. He received his medical degree from Drexel University College of Medicine/Hahnemann University and has been in practice 50 years. He is experienced in cholangiocarcinoma, gastrointestinal oncology, general medical oncology, and endocrine oncology. He has more than 100 publications and over 500 citings.

Office
Memorial Sloan Kettering Cancer Center Bergen
225 Summit Avenue
New York, NY 10021
Book by Phone+1(561) 537-3494
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Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 1976 - 1978
Temple University HospitalResidency, Internal Medicine, 1972 - 1976
Drexel University College of MedicineClass of 1972

Certifications & Licensure

FL State Medical License 2022 - Present
NY State Medical License 1976 - 2025
NJ State Medical License 2019 - 2025
PA State Medical License 1973 - 1990
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2003-2014
Top Doctors: New York Metro Area Castle Connolly, 2002-2014
New York Magazine: Top Doctors Castle Connolly, 2002-2009, 2011-2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013
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Clinical Trials

Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus Start of enrollment: 1995 Oct 01
Completed
Phase 1
Combination Chemotherapy Before and After Surgery in Treating Patients With Stomach Cancer Start of enrollment: 1996 May 01
Completed
Phase 2
Paclitaxel in Treating Patients With Metastatic, Recurrent, or Unresectable Cancer of the Esophagus Start of enrollment: 1997 Sep 01
Unknown status
Phase 2
Gemcitabine Plus Radiation Therapy in Treating Patients With Pancreatic Cancer Start of enrollment: 1998 Apr 01
Completed
Phase 1
Combination Chemotherapy Followed by Surgery and Intraperitoneal Chemotherapy in Treating Patients With Locally Advanced Stomach Cancer Start of enrollment: 2000 Feb 01
Completed
Phase 2
Chemotherapy and Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Stomach Who Have Undergone Surgery Start of enrollment: 2001 May 01
Completed
Phase 2
Study of Modified Docetaxel, Cisplatin, and Fluorouracil (mDCF) in Unresectable or Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma Start of enrollment: 2006 Oct 23
Completed
Phase 2
Early Onset and Familial Gastric Cancer Registry Start of enrollment: 2005 Dec 01
Active, not recruiting
A Registry for BRCA Mutation Carriers With Pancreatic Ductal Adenocarcinoma Start of enrollment: 2013 Nov 04
Recruiting
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Publications & Presentations

PubMed

Identifying Genetic Loci Associated with an Increased Risk for Early Onset Colorectal Cancer.
Irit Ben-Aharon, Noa Gordon, David Kelsen> ;Annals of Oncology. 2024 Apr 3
Assessment of the Feasibility of Hyperpolarized [1-C]pyruvate Whole-Abdomen MRI using DO Solvation in Humans.
Guannan Zhang, Kofi Deh, Hijin Park, Charles H Cunningham, Nadia D Bragagnolo, Serge Lyashchenko, Shake Ahmmed, Avigdor Leftin, Elizabeth Coffee, David Kelsen, Hedvig ...> ;Journal of Magnetic Resonance Imaging. 2024 Mar 5
1 citations
Pharmaceutical Agents as Potential Drivers in the Development of Early-Onset Colorectal Cancer: Case-Control Study.
Irit Ben-Aharon, Ran Rotem, Gilad Twig, Andrea Cercek, Elizabeth Half, Gabriel Chodik, David Kelsen, Melzer-Cohen, C., Goshen-Lago, T.> ;JMIR Public Health and Surveillance. 2023 Dec 13
4 citations
Perioperative versus total neoadjuvant chemotherapy in gastric cancer.
Jessica Yang, Megan Greally, Vivian E Strong, Daniel G Coit, Joanne F Chou, Marinela Capanu, Steven B Maron, David P Kelsen, David H Ilson, Yelena Y Janjigian, Geoffre...> ;Journal of Gastrointestinal Oncology. 2023 Jun 30
24 citations
Tumour extracellular vesicles and particles induce liver metabolic dysfunction.
Gang Wang, Jianlong Li, Linda Bojmar, Haiyan Chen, Zhong Li, Gabriel C Tobias, Mengying Hu, Edwin A Homan, Serena Lucotti, Fengbo Zhao, Valentina Posada, Peter R Oxley...> ;Nature. 2023 Jun 1
5 citations
Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers.
Walid K Chatila, Henry Walch, Jaclyn F Hechtman, Sydney M Moyer, Valeria Sgambati, David M Faleck, Amitabh Srivastava, Laura Tang, Jamal Benhamida, Dorina Ismailgeci, ...> ;Nature Communications. 2023 Jan 7
17 citations
BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling.
Lee Shaashua, Aviad Ben-Shmuel, Meirav Pevsner-Fischer, Gil Friedman, Oshrat Levi-Galibov, Subhiksha Nandakumar, Debra Barki, Reinat Nevo, Lauren E Brown, Wenhan Zhang...> ;Nature Communications. 2022 Oct 31
1 citations
Attitudes toward preimplantation genetic testing and quality of life among individuals with hereditary diffuse gastric cancer syndrome.
Ibrahim H Shah, Erin E Salo-Mullen, Kimberly A Amoroso, David Kelsen, Zsofia K Stadler, Jada G Hamilton> ;Hereditary Cancer in Clinical Practice. 2022 Sep 2
8 citations
Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice.
Wungki Park, Catherine A O'Connor, Chaitanya Bandlamudi, Daniella Forman, Joanne F Chou, Shigeaki Umeda, Marsha Reyngold, Anna M Varghese, Fergus Keane, Fiyinfolu Balo...> ;Clinical Cancer Research. 2022 Nov 1
2 citations
PD-L1 expression and overall survival in Asian and western patients with gastric cancer.
Sun Young Rha, Geoffrey Y Ku, Hyo Song Kim, Hyun Cheol Chung, Fatemeh Ghazanfari Amlashi, Dipen Maheshbhai Maru, Carly A Fein, Laura H Tang, Wei Zhou, Ting Wu, Senaka ...> ;Future Oncology. 2022 Jul 1
2 citations
Circulating tumor and invasive cell expression profiling predicts effective therapy in pancreatic cancer.
Kenneth H Yu, Jennifer Park, Avni Mittal, Ghassan K Abou-Alfa, Imane El Dika, Andrew S Epstein, David H Ilson, David P Kelsen, Geoffrey Y Ku, Jia Li, Wungki Park, Anna...> ;Cancer. 2022 Aug 1
17 citations
Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients.
Ori Hassin, Nishanth Belugali Nataraj, Michal Shreberk-Shaked, Yael Aylon, Rona Yaeger, Giulia Fontemaggi, Saptaparna Mukherjee, Martino Maddalena, Adi Avioz, Ortal Ia...> ;Nature Communications. 2022 May 19
1 citations
Phase I/Ib study of crenolanib with ramucirumab and paclitaxel as second-line therapy for advanced esophagogastric adenocarcinoma.
Ryan H Moy, Megan Greally, Joanne F Chou, Jia Li, Avni M Desai, Sree B Chalasani, Elizabeth Won, David P Kelsen, David H Ilson, Yelena Y Janjigian, Marinela Capanu, Ge...> ;Cancer Chemotherapy and Pharmacology. 2022 Feb 1
3 citations
Prognostic significance of T-cell-inflamed gene expression profile and PD-L1 expression in patients with esophageal cancer.
Torben Steiniche, Sun Young Rha, Hyun Cheol Chung, Jeanette Bæhr Georgsen, Morten Ladekarl, Marianne Nordsmark, Marie Louise Jespersen, Hyo Song Kim, Hyunki Kim, Carly...> ;Cancer Medicine. 2021 Oct 24
31 citations
Early-Onset Pancreas Cancer: Clinical Descriptors, Genomics, and Outcomes
Singh, R., Anna M. Varghese, Isha Singh, Ritu Raj Singh, Siddharth Kunte, Joanne F. Chou, Marinela Capanu, Winston Wong, Maeve A. Lowery, Zsofia K. Stadler, Erin E. Sa...> ;Journal of the National Cancer Institute. 2021 Sep 4
18 citations
Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes.
Parisa Momtaz, Catherine A. O’Connor, Joanne F. Chou, Marinela Capanu, Wungki Park, Chaitanya Bandlamudi, Michael F. Berger, David P. Kelsen, Sarah P. Suehnholz, Debya...> ;Cancer. 2021 Aug 5
12 citations
Prevalence of Germline Alterations on Targeted Tumor-Normal Sequencing of Esophagogastric Cancer.
Geoffrey Y. Ku, Yelena Kemel, Steve B. Maron, Joanne F. Chou, Vignesh Ravichandran, Zarina Shameer, Anna Maio, Elizabeth Won, David P. Kelsen, David H. Ilson, Marinela...> ;JAMA Network Open. 2021 Jul 1
3 citations
Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill
Vishnu Mohan, Jean P. Gaffney, Inna Solomonov, Maxim Levin, Mordehay Klepfish, Sophia Akbareian, Barbara Grünwald, Orly Dym, Miriam Eisenstein, Kenneth H. Yu, David P....> ;Cancers. 2021 Apr 2
19 citations
Characterization and Clinical Outcomes of DNA Mismatch Repair-deficient Small Bowel Adenocarcinoma.
Alicia Latham, Jinru Shia, Zalak Patel, Diane Reidy-Lagunes, Neil H. Segal, Rona Yaeger, Karuna Ganesh, Louise Catherine Connell, Nancy E. Kemeny, David P. Kelsen, Jac...> ;Clinical Cancer Research. 2021 Mar 1
12 citations
Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids.
Linda Bojmar, Han Sang Kim, Gabriel C. Tobias, Fanny A. Pelissier Vatter, Serena Lucotti, Kofi Ennu Gyan, Candia M. Kenific, Zurong Wan, Kyung A. Kim, DooA Kim, Jonath...> ;STAR Protocols. 2021 Mar 19
39 citations
Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer
Oshrat Levi-Galibov, Hagar Lavon, Rina Wassermann-Dozorets, Meirav Pevsner-Fischer, Shimrit Mayer, Esther Wershof, Yaniv Stein, Lauren E. Brown, Wenhan Zhang, Gil Frie...> ;Nature Communications. 2020 Dec 7
24 citations
Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers.
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Iscience. 2020 Nov 25
16 citations
Induction and characterization of pancreatic cancer in a transgenic pig model.
F. Edward Boas, Fuad Nurili, Achiude Bendet, C. Cheleuitte-Nieves, Olca Basturk, Gokce Askan, Adam O. Michel, Sebastien Monette, Etay Ziv, Constantinos T. Sofocleous, ...> ;Plos One. 2020 Sep 21
42 citations
Alterations in driver genes are predictive of survival in patients with resected pancreatic ductal adenocarcinoma
Caitlin A. McIntyre, Sharon A. Lawrence, Allison Richards, Joanne F. Chou, Winston Wong, Marinela Capanu, Michael F. Berger, Mark T.A. Donoghue, Kenneth H. Yu, Anna M....> ;Cancer. 2020 Sep 1
569 citations
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
Ayuko Hoshino, Han Sang Kim, Linda Bojmar, Kofi Ennu Gyan, Michele Cioffi, Jonathan M. Hernandez, Constantinos P. Zambirinis, Gonçalo Rodrigues, Henrik Molina, Søren H...> ;Cell. 2020 Aug 20
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Authored Content

Phase II Trial of Veliparib in Patients with Previously Treated BRCA-Mutated Pancreas Ductal Adenocarcinoma☆January 2018

Press Mentions

Stress Response Protein Links Inflammatory Disease to Colon CancerFebruary 19th, 2021
Novo Nordisk's Drug for Obesity Treatment Gets FDA Panel ApprovalSeptember 12th, 2014
U.S. FDA Panel: Novo Nordisk's Liraglutide Safe, Effective for ObesitySeptember 11th, 2014

Grant Support

Early Therapeutics Development With Phase II EmphasisNational Cancer Institute2011
Early Therapeutics Development With Phase II EmphasisNational Cancer Institute2010
Tas:: 75 0850 ::Tas Recovery ACT - Actnow Clinical Trial 8461Division Of Cancer Treatment2009
Early Therapeutics Development With Phase II EmphasisDivision Of Cancer Treatment2009
Phase II/III Clinical Trials Of Anticancer AgentsNational Cancer Institute1995–2000
Neoadjuvant Therapy And Bio-Correlates Of Gastric CancerNational Cancer Institute1996–1998
Pain Relief In Pancreas CancerNational Cancer Institute1993–1995
Multimodality Treatment &Clinical-Biological CorrelatesNational Cancer Institute1992–1993
Multimodality Treatment &Clinical-Biological CorrelatesNational Cancer Institute1991
Pain Assessment In Patients With Pancreas CancerNational Cancer Institute1989–1991
Mskcc CCOP Research Base OperationsNational Cancer Institute1987–1990
C C O P Research Base OperationsNational Cancer Institute1985–1986

Hospital Affiliations

Memorial Sloan Kettering Cancer CenterNew York, New York

Insurance Accepted

Aetna Choice POS II
Aetna HMO
BCBS Blue Card PPO
BCBS Illinois PPO
BCBS Kansas City Preferred-Care Blue PPO
CIGNA HMO
CIGNA Open Access
CIGNA PPO
Empire BCBS HMO
Empire BCBS PPO
GHI PPO
Great West PPO
Humana ChoiceCare Network PPO
Multiplan PHCS PPO
Multiplan PPO
MVP Healthcare PPO
Oxford Health Freedom
Oxford Health Liberty
QualCare HMO
QualCare PPO
United Healthcare - Direct Choice Plus POS
United Healthcare - Direct Options PPO
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