DavidSLarsenMDBoard Cert Neurologist

PubMed

• Resolution of orthogonally protected myo-inositols with novozym 435 providing an enantioconvergent pathway to Ac2PIM1.
  Lee AMM, Painter GF, Compton BJ, Larsen DS> ;J. Org. Chem.. 2014-11-21
• The dimethoxyphenylbenzyl protecting group: an alternative to the p-methoxybenzyl group for protection of carbohydrates.
  Rankin GM, Maxwell-Cameron I, Painter GF, Larsen DS> ;J. Org. Chem.. 2013-06-07
• Synthesis and mass spectral characterization of mycobacterial phosphatidylinositol and its dimannosides.
  Rankin GM, Compton BJ, Johnston KA, Hayman CM, Painter GF, Larsen DS> ;J. Org. Chem.. 2012-08-17
• Synthesis and Toll-like Receptor 4 (TLR4) Activity of Phosphatidylinositol Dimannoside Analogues.
  Ainge, G.D., Martin, W.J., Compton, B.J., Hayman, C.M., Larsen, D.S., Yoon, S., Wilson, I.A., Harper, J.L., Painter, G.F.> ;J Med Chem. 2011 Oct 27
• A family of 13 tetranuclear zinc(ii)-lanthanide(iii) complexes of a [3 + 3] Schiff-base macrocycle derived from 1,4-diformyl-2,3-dihydroxybenzene.
  Feltham, H. L., Klöwer, F., Cameron, S. A., Larsen, D. S., Lan, Y., Tropiano, M., Faulkner, S., Powell, A. K., Brooker, S.> ;Dalton Trans. 2011 Nov 21
• Chemical synthesis and immunosuppressive activity of dipalmitoyl phosphatidylinositol hexamannoside.
  Ainge, G.D., Compton, B.J., Hayman, C.M., Martin, W.J., Toms, S.M., Larsen, D.S., Harper, J.L., Painter, G.F.> ;J Org Chem. 2011 Jun 17
• Role of phosphatidylinositol mannosides in the interaction between mycobacteria and DC-SIGN.
  Driessen, N.N., Ummels, R., Maaskant, J.J., Gurcha, S.S., Besra, G.S., Ainge, G.D., Larsen, D.S., Painter, G.F., Vandenbroucke-Grauls, C.E., Geurtsen, J., Appelmelk, B.J.> ;Infect Immun. 2009-10-01
• A synthetic analogue of phosphatidylinositol mannoside is an efficient adjuvant.
  > ;Immunopharmacol Immunotoxicol. 2009-05-12
• Phosphatidylinositol mannosides are efficient mucosal adjuvants.
  Parlane, N.A., Denis, M., Severn, W.B., Skinner, M.A., Painter, G.F., La Flamme, A.C., Ainge, G.D., Larsen, D.S., Buddle, B.M.> ;Immunol Invest. 2008
• Phosphatidylinositol mannoside ether analogues: syntheses and interleukin-12-inducing properties.
  Ainge, G. D., Parlane, N. A., Denis, M., Dyer, B. S., Härer, A., Hayman, C. M., Larsen, D. S., Painter, G. F.> ;J Org Chem. 2007 Jul 6
• Synthesis and structure of phosphatidylinositol dimannoside.
  Dyer, B.S., Jones, J.D., Ainge, G.D., Denis, M., Larsen, D.S., Painter, G.F.> ;J Org Chem. 2007 Apr 27
• Oligosaccharides related to xyloglucan: synthesis and X-ray crystal structure of methyl alpha-L-fucopyranosyl-(1-->2)-beta-D-galactopyranosyl-(1-->2)-alpha-D-x ylopyra...
  Watt, D. K., Brasch, D. J., Larsen, D. S., Melton, L. D., Simpson, J.> ;Carbohydr Res. 2000 May 5
• Oligosaccharides related to xyloglucan: synthesis and X-ray crystal structure of methyl 2-0-(alpha-L-fucopyranosyl)-beta-D-galactopyranoside.
  Watt, D. K., Brasch, D. J., Larsen, D. S., Melton, L. D., Simpson, J.> ;Carbohydr Res. 1996 May 14
• Total synthesis of (+)-hatomarubigin B.
  Caygill, G. B., Larsen, D. S., Brooker, S.> ;J Org Chem. 2001 Nov 2
• Dicopper(II) complexes of a new pyrazolate-containing Schiff-base macrocycle and related acyclic ligand.
  de Geest, D. J., Noble, A., Moubaraki, B., Murray, K. S., Larsen, D. S., Brooker, S.> ;Dalton Trans. 2007 Jan 28
• Phosphatidylinositol mannosides: synthesis and adjuvant properties of phosphatidylinositol di- and tetramannosides.
  Ainge, G. D., Parlane, N. A., Denis, M., Hayman, C. M., Larsen, D. S., Painter, G. F.> ;Bioorg Med Chem. 2006 Nov 15
• A stereoselective synthesis of 6,6,6-trifluoro-L-daunosamine and 6,6,6-trifluoro-L-acosamine.
  Hayman, C. M., Larsen, D. S., Simpson, J., Bailey, K. B., Gill, G. S.> ;Org Biomol Chem. 2006 Jul 21
• Phosphatidylinositol mannosides: synthesis and suppression of allergic airway disease.
  Ainge, G. D., Hudson, J., Larsen, D. S., Painter, G. F., Gill, G. S., Harper, J. L.> ;Bioorg Med Chem. 2006 Aug 15
• Studies related to carba-pyranoses: a radical decarboxylation approach to monocarba-disaccharides.
  Larsen, D. S., Lins, R. J., Stoodley, R. J., Trotter, N. S.> ;Org Biomol Chem. 2004 Jul 7
• 4-(Pyrrol-1-yl)-1,2,4-triazole.
  Hellyer, R. M., Joule, J. A., Larsen, D. S., Brooker, S.> ;Acta Crystallogr C. 2007 Jun
• A PIM₂ analogue suppresses allergic airway disease.
  Harper, J. L., Hayman, C. M., Larsen, D. S., Painter, G. F., Singh-Gill, G.> ;Bioorg Med Chem. 2011 Jan 15
• Phenyl 2,3-O-isopropyl-idene-1-thio-α-d-rhamnopyran-oside.
  Osman, H., Larsen, D. S., Hanton, L. R., Simpson, J.> ;Acta Crystallogr Sect E Struct Rep Online. 2007
• Alkylations of N(4)-(4-pyridyl)-3,5-di(2-pyridyl)-1,2,4-triazole: first observation of room-temperature rearrangement of an N(4)-substituted triazole to the N(1) analo...
  Kitchen, J. A., Larsen, D. S., Brooker, S.> ;Chem Asian J. 2010 Apr 1
• A synthetic analogue of phosphatidylinositol mannoside is an efficient adjuvant.
  Denis, M., Ainge, G. D., Larsen, D. S., Severn, W. B., Painter, G. F.> ;Immunopharmacol Immunotoxicol. 2009 Oct 31
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