DavidMarguliesMD

PubMed

• Crystal structure of a TAPBPR-MHC-I complex reveals the mechanism of peptide editing in antigen presentation.
  Jiang, J.,Natarajan, K.,Boyd, L. F.,Morozov, G. I.,Mage, M. G.,Margulies, D. H.> ;Science. 1900 Jan 01
• Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy.
  Ronny Peri-Naor, Leila Motiei, David Margulies> ;Journal of Visualized Experiments. 2016 Sep 29
• Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock.
  Voss OH, Murakami Y, Pena MY, Lee H, Tian L, Margulies DH, Street JM, Yuen PST, Qi C, Krzewski K, Coligan JE> ;Immunity. 2016-06-21
• 69 citations
  Message in a molecule
  Tanmay Sarkar, Karuthapandi Selvakumar, Leila Motiei, David Margulies> ;Nature Communications. 2016 May 3
• Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing.
  Morozov, G. I.,Zhao, H.,Mage, M. G.,Boyd, L. F.,Jiang, J.,Dolan, M. A.,Venna, R.,Norcross, M. A.,McMurtrey, C. P.,Hildebrand, W.,Schuck, P.,Natarajan, K.,Margulies, D. H.> ;Proc. Natl. Acad. Sci. U.S.A.. 2016 Feb 13
• A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR.
  Sgourakis NG, May NA, Boyd LF, Ying J, Bax A, Margulies DH> ;J. Biol. Chem.. 2015-11-27
• 18 citations
  The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism
  Julia Guez-Haddad, Michael Sporny, Yehezkel Sasson, Lada Gevorkyan-Airapetov, Naama Lahav-Mankovski, David Margulies, Jens Radzimanowski, Yarden Opatowsky> ;Structure. 2015 Nov 3
• Sensing Protein Surfaces with Targeted Fluorescent Receptors.
  Nissinkorn Y, Lahav-Mankovski N, Rabinkov A, Albeck S, Motiei L, Margulies D> ;Chemistry. 2015-11-02
• Sensing Protein Surfaces with Targeted Fluorescent Receptors.
  Nissinkorn Y, Lahav-Mankovski N, Rabinkov A, Albeck S, Motiei L, Margulies D> ;Chemistry. 2015-11-02
• William E. Paul 1936-2015.
  Shevach, E. M.,Margulies, D. H.> ;Nat. Immunol.. 2015 Nov 19
• 3 citations
  Artificial signal transduction therapy: a futuristic approach to disease treatment
  Ronny Peri-Naor, Leila Motiei, David Margulies> ;Future Medicinal Chemistry. 2015 Oct 29
• The cellular environment regulates in situ kinetics of T-cell receptor interaction with peptide major histocompatibility complex.
  Liu B, Chen W, Natarajan K, Li Z, Margulies DH, Zhu C> ;Eur. J. Immunol.. 2015-07-01
• 29 citations
  Protein-Protein Communication and Enzyme Activation Mediated by a Synthetic Chemical Transducer.
  Ronny Peri-Naor, Tal Ilani, Leila Motiei, David Margulies> ;Journal of the American Chemical Society. 2015 Jun 23
• 24 citations
  Enzyme−Artificial Enzyme Interactions as a Means for Discriminating among Structurally Similar Isozymes
  Karuthapandi Selvakumar, Leila Motiei, David Margulies> ;Journal of the American Chemical Society. 2015 Apr 14
• The Structure of Mouse Cytomegalovirus m04 Protein Obtained from Sparse NMR Data Reveals a Conserved Fold of the m02-m06 Viral Immune Modulator Family.
  Sgourakis, N. G.,Natarajan, K.,Ying, J.,Vogeli, B.,Boyd, L. F.,Margulies, D. H.,Bax, A.> ;Structure. 2014 Aug 16
• 49 citations
  Targeted Protein Surface Sensors as a Tool for Analyzing Small Populations of Proteins in Biological Mixtures
  Leila Motiei, Zohar Pode, Anna Koganitsky, David Margulies> ;Angewandte Chemie. 2014 Aug 25
• The in-betweeners: MAIT cells join the innate-like lymphocytes gang.
  Margulies DH> ;J. Exp. Med.. 2014-07-28
• 65 citations
  CD300b regulates the phagocytosis of apoptotic cells via phosphatidylserine recognition
  Yousuke Murakami, Linjie Tian, Oliver H. Voss, David H. Margulies, Konrad Krzewski, John E. Coligan> ;Cell Death and Differentiation. 2014 Jul 18
• 61 citations
  Authorizing Multiple Chemical Passwords by a Combinatorial Molecular Keypad Lock
  Bhimsen Rout, Petr Milko, Mark A. Iron, Leila Motiei, David Margulies> ;Journal of the American Chemical Society. 2013 Oct 2
• A structural and molecular dynamics approach to understanding the peptide-receptive transition state of MHC-I molecules.
  Mage, M. G.,Dolan, M. A.,Wang, R.,Boyd, L. F.,Revilleza, M. J.,Robinson, H.,Natarajan, K.,Myers, N. B.,Hansen, T. H.,Margulies, D. H.> ;Mol. Immunol.. 2013 Sep
• Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1γ reveals a paradigm for MHC/MHC interaction in immune evasion.
  Wang R, Natarajan K, Revilleza MJR, Boyd LF, Zhi L, Zhao H, Robinson H, Margulies DH> ;Proc. Natl. Acad. Sci. U.S.A.. 2012-12-18
• 51 citations
  Medication Detection by a Combinatorial Fluorescent Molecular Sensor
  Bhimsen Rout, Linor Unger, Gad Armony, Mark A. Iron, David Margulies> ;Angewandte Chemie. 2012 Dec 7
• The peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
  Mage MG, Dolan MA, Wang R, Boyd LF, Revilleza MJ, Robinson H, Natarajan K, Myers NB, Hansen TH, Margulies DH> ;J. Immunol.. 2012-08-01
• Abacavir induces loading of novel self-peptides into HLA-B*57: 01: an autoimmune model for HLA-associated drug hypersensitivity.
  Norcross MA, Luo S, Lu L, Boyne MT, Gomarteli M, Rennels AD, Woodcock J, Margulies DH, McMurtrey C, Vernon S, Hildebrand WH, Buchli R> ;AIDS. 2012-07-17
• High-throughput sequencing of mGluR signaling pathway genes reveals enrichment of rare variants in autism.
  Kelleher RJ, Geigenmüller U, Hovhannisyan H, Trautman E, Pinard R, Rathmell B, Carpenter R, Margulies D> ;PLoS ONE. 2012-01-01
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