DavidMMarkovitzMD

PubMed

• 9 citations
  Novel banana lectin CAR-T cells to target pancreatic tumors and tumor-associated stroma.
  Mary K McKenna, Ada Ozcan, Daniel Brenner, Norihiro Watanabe, Maureen Legendre, Dafydd G Thomas, Christopher Ashwood, Richard D Cummings, Challice Bonifant, David M Ma...> ;Journal for Immunotherapy of Cancer. 2023 Jan 1
• 4 citations
  Centromere defects, chromosome instability, and cGAS-STING activation in systemic sclerosis.
  Souren Paul, Mark H Kaplan, Dinesh Khanna, Preston M McCourt, Anjan K Saha, Pei-Suen Tsou, Mahek Anand, Alexander Radecki, Mohamad Mourad, Amr H Sawalha, David M Marko...> ;Nature Communications. 2022 Nov 18
• 11 citations
  A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo.
  Jasper Fuk-Woo Chan, Yoo Jin Oh, Shuofeng Yuan, Hin Chu, Man-Lung Yeung, Daniel Canena, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Chris Chun-Yiu Chan, Anna Jinxia ...> ;Cell Reports. Medicine. 2022 Oct 18
• 3 citations
  DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Gαi signaling.
  Maegan L Capitano, Yasser Sammour, James Ropa, Maureen Legendre, Nirit Mor-Vaknin, David M Markovitz> ;Journal of Leukocyte Biology. 2022 Sep 1
• 12 citations
  Targeting glycans for CAR therapy: The advent of sweet CARs.
  Zoe Raglow, Mary Kathryn McKenna, Challice L Bonifant, Wenjing Wang, Marina Pasca di Magliano, Johannes Stadlmann, Josef M Penninger, Richard D Cummings, David M Marko...> ;Molecular Therapy. 2022 Sep 7
• 8 citations
  H84T BanLec has broad spectrum antiviral activity against human herpesviruses in cells, skin, and mice.
  M G Lloyd, D Liu, M Legendre, D M Markovitz, J F Moffat> ;Scientific Reports. 2022 Jan 31
• Response to Berry et al's "Cutaneous small-vessel vasculitis following single-dose Janssen Ad26.COV2.S vaccination".
  Natalie H Matthews, Cayla M Pichan, Alexandra C Hristov, David M Markovitz, Allison M Darland> ;JAAD Case Reports. 2022 Nov 1
• 7 citations
  The Use of Lectins as Tools to Combat SARS-CoV-2.
  Daniela Martinez, Diego Amaral, David M. Markovitz, Luciano da Silva Pinto> ;Current Pharmaceutical Design. 2021 Aug 29
• 11 citations
  Targeted disruption of pi-pi stacking in Malaysian banana lectin reduces mitogenicity while preserving antiviral activity.
  Evelyn M. Covés-Datson, Steven R. King, Maureen Legendre, Michael D. Swanson, Auroni Gupta, Sandra Claes, Jennifer L. Meagher, Arnaud Boonen, Lihong Zhang, Birte Kalve...> ;Scientific Reports. 2021 Jan 12
• 10 citations
  Glycoprotein Targeted CAR-NK Cells for the Treatment of SARS-CoV-2 Infection.
  Ilias Christodoulou, Ruyan Rahnama, Jonas W Ravich, Jaesung Seo, Sergey N Zolov, Andrew N Marple, David M Markovitz, Challice L Bonifant> ;Frontiers in Immunology. 2021 Jan 1
• 33 citations
  The role of the histone H3 variant CENPA in prostate cancer
  Anjan K. Saha, Rafael Contreras-Galindo, Yashar S. Niknafs, Matthew K. Iyer, Tingting Qin, Karthik R. Padmanabhan, Javed Siddiqui, Monica Palande, Claire L. Wang, Bria...> ;The Journal of Biological Chemistry. 2020 Jun 19
• 9 citations
  Anti-vimentin antibodies: a unique antibody class associated with therapy-resistant lupus nephritis:
  Andrew J Kinloch, Matthew D Cascino, Jian Dai, Rene S. Bermea, Kichul Ko, Margaret Vesselits, Leonard L Dragone, Nirit Mor Vaknin, Maureen Legendre, David M. Markovitz...> ;Lupus. 2020 Mar 26
• 44 citations
  A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo.
  Evelyn M. Covés-Datson, Steven R. King, Maureen Legendre, Auroni Gupta, Susana M. Chan, Emily Gitlin, Vikram V. Kulkarni, Jezreel Pantaleón García, Donald F. Smee, Elk...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Jan 28
• 17 citations
  The Genomic Landscape of Centromeres in Cancers.
  Anjan K. Saha, Mohamad Mourad, Mark H. Kaplan, Ilana Chefetz, Sami N. Malek, Ronald J. Buckanovich, David M. Markovitz, Rafael Contreras-Galindo> ;Scientific Reports. 2019 Aug 2
• 33 citations
  Inhibition of Ebola Virus by a Molecularly Engineered Banana Lectin.
  Evelyn M. Covés-Datson, Julie Dyall, Lisa Evans DeWald, Steven R. King, Derek Dube, Maureen Legendre, Elizabeth A. Nelson, Kelly Drews, Robin Gross, Dawn M. Gerhardt, ...> ;Plos Neglected Tropical Diseases. 2019 Jul 29
• 23 citations
  Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling
  Maegan L. Capitano, Nirit Mor-Vaknin, Anjan K. Saha, Scott Cooper, Maureen Legendre, Haihong Guo, Rafael Contreras-Galindo, Ferdinand Kappes, Maureen A. Sartor, Christ...> ;The Journal of Clinical Investigation. 2019 Jun 3
• 27 citations
  The HERV-K accessory protein Np9 controls viability and migration of teratocarcinoma cells.
  Susana M. Chan, Tamar Sapir, Sung Soo Park, Jean François Rual, Rafael Contreras-Galindo, Orly Reiner, David M. Markovitz> ;Plos One. 2019 Feb 28
• 10 citations
  The DEK Oncoprotein Functions in Ovarian Cancer Growth and Survival.
  Kari E. Hacker, Danielle E. Bolland, Lijun Tan, Anjan K. Saha, Yashar S. Niknafs, David M. Markovitz, Karen McLean> ;Neoplasia. 2018 Dec 1
• 10 citations
  High Levels of DEK Autoantibodies in Sera of Patients With Polyarticular Juvenile Idiopathic Arthritis and With Early Disease Flares Following Cessation of Anti-Tumor ...
  Nirit Mor-Vaknin, Miguel Rivas, Maureen Legendre, Smriti Mohan, Ye Yuanfan, Theresa Mau, Anne Johnson, Bin Huang, Lili Zhao, Yukiko Kimura, Steven J. Spalding, Paula W...> ;Arthritis & Rheumatology. 2018 Feb 22
• 64 citations
  Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin
  Pallab Ghosh, Elizabeth M. Halvorsen, Dustin A. Ammendolia, Nirit Mor-Vaknin, Mary X. D. O'Riordan, John H. Brumell, David M. Markovitz, Darren E. Higgins> ;Mbio. 2018 Mar 7
• 30 citations
  Susceptibility of Human Endogenous Retrovirus Type K to Reverse Transcriptase Inhibitors.
  Rafael Contreras-Galindo, Derek Dube, Koh Fujinaga, Mark H. Kaplan, David M. Markovitz> ;Journal of Virology. 2017 Dec 1
• 17 citations
  Rapid molecular assays to study human centromere genomics.
  Rafael Contreras-Galindo, Sabrina Fischer, Anjan K. Saha, John D Lundy, Patrick W Cervantes, Mohamad Mourad, Claire L. Wang, Brian Qian, Manhong Dai, Fan Meng, Arul M....> ;Genome Research. 2017 Nov 15
• 58 citations
  DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis
  Nirit Mor-Vaknin, Anjan K. Saha, Maureen Legendre, Carmelo Carmona-Rivera, M. Asif Amin, Bradley J. Rabquer, Marta J Gonzales-Hernandez, Julie M. Jorns, Smriti Mohan, ...> ;Nature Communications. 2017 Feb 6
• 26 citations
  Why Do Membranes of Some Unhealthy Cells Adopt a Cubic Architecture
  Qi Xiao, Zhichun Wang, Dewight Williams, Pawaret Leowanawat, Mihai Peterca, Samuel E. Sherman, Shaodong Zhang, Daniel A. Hammer, Paul A. Heiney, Steven R. King, David ...> ;ACS Central Science. 2016 Dec 5
• 34 citations
  Vimentin, a Novel NF-κB Regulator, Is Required for Meningitic Escherichia coli K1-Induced Pathogen Invasion and PMN Transmigration across the Blood-Brain Barrier.
  Sheng He Huang, Feng Chi, Liang Peng, Tao Bo, Bao Zhang, Li Qun Liu, Xuedong Wu, Nirit Mor-Vaknin, David M. Markovitz, Hong Cao, Yanhong Zhou> ;Plos One. 2016 Sep 22
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Journal Articles

• Engineering a therapeutic lectin: uncoupling mitogenicity from antiviral activity  
  Swanson, et al., Cell

Abstracts/Posters

• Hematopoietic Stem and Progenitor Cells Manifest Direct Migration Towards Secreted DEK in a CXCR2- and G Protein Signaling-Dependent Manner
  David Markovitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019