David G McFadden MD PhD
Diabetes, Lipid Metabolism, Thyroid
Assistant Professor, UT Southwestern Medical Center
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5323 Harry Hines BlvdDallas, TX 75390
Phone+1 214-648-3494
Fax+1 214-648-8917
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Education & Training
Mass General Brigham/Massachusetts General HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 2006 - 2009
Mass General Brigham/Brigham and Women's HospitalResidency, Internal Medicine, 2004 - 2006
University of Texas Southwestern Medical SchoolClass of 2004
Certifications & Licensure
TX State Medical License 2014 - 2025
MA State Medical License 2006 - 2015
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Publications & Presentations
PubMed
- Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts.James H McGinnis, Alberto Bremauntz Enriquez, Florentina Vandiver, Xin Bai, Jiwoong Kim
Biorxiv. 2024-10-29 - 2 citationsForward Genetic Screens Identify Mechanisms of Resistance to Small-Molecule Lactate Dehydrogenase Inhibitors.Anderson R Frank, Florentina Vandiver, David G McFadden
ACS Chemical Biology. 2024-02-16 - 3 citationsInducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules.Thu P Nguyen, Min Fang, Jiwoong Kim, Baiyun Wang, Elisa Lin
Cell Chemical Biology. 2023-11-16
Press Mentions
UConn Health Introduces Chief of Cardiothoracic SurgeryAugust 19th, 2021- Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?January 30th, 2020
Oncology: Emerging Clinical Investigators Stars Receive Damon Runyan AwardsJuly 23rd, 2019
Grant Support
- Targeting transcriptional addiction in fusion-driven sarcomaUT SOUTHWESTERN MEDICAL CENTER2024–2029
- Identifying metabolic dependencies in Hurthle cell carcinoma of the thyroid-Res 1UT SOUTHWESTERN MEDICAL CENTER2023–2028
- Targeting EWSR1-FLI1 through Functional, Structural and Chemical ApproachesUT SOUTHWESTERN MEDICAL CENTER2019–2025
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