DavidJonMillerMDPhD

PubMed

• 1 citations
  Synthesis and biological activity of conformationally restricted indole-based inhibitors of neurotropic alphavirus replication: Generation of a three-dimensional pharm...
  Scott J. Barraza, Janice A. Sindac, Craig J. Dobry, Philip C. Delekta, Pil H. Lee, David J. Miller, Scott D. Larsen> ;Bioorganic & Medicinal Chemistry Letters. 2021 Jun 4
• 90 citations
  Heat Shock Proteins Regulatory Role in Neurodevelopment.
  David J. Miller, Patrice Fort> ;Frontiers in Neuroscience. 2018 Nov 12
• 21 citations
  Establishment of a Web-based System for Collection of Patient-reported Outcomes After Radical Prostatectomy in a Statewide Quality Improvement Collaborative.
  Lucas, S. M., Lucas, S. M., Lucas, S. M., Kim, T. K., Kim, T. K., Kim, T. K., Ghani, K. R., Ghani, K. R., Ghani, K. R., Miller, D. C., Miller, D. C., Miller, D. C., Li...> ;Urology. 2017 Jun 28
• 20 citations
  Successful Treatment of a Mycotic Multifocal Thoracoabdominal Aortic Aneurysm as a Late Sequelae of Intravesical Bacillus Calmette-Guerin Therapy: Case Report and Lite...
  Frank M. Davis, David J. Miller, Duane W. Newton, Shipra Arya, Guillermo A. Escobar> ;Annals of Vascular Surgery. 2015 May 1
• 10 citations
  Discovery of anthranilamides as a novel class of inhibitors of neurotropic alphavirus replication.
  Scott J. Barraza, Philip C. Delekta, Janice A. Sindac, Craig J. Dobry, Jianming Xiang, Richard F. Keep, David J. Miller, Scott D. Larsen> ;Bioorganic & Medicinal Chemistry. 2015 Apr 1
• 6 citations
  The combined use of alphavirus replicons and pseudoinfectious particles for the discovery of antivirals derived from natural products.
  Phillip C. Delekta, Avi Raveh, Martha J. Larsen, Pamela J. Schultz, Giselle Tamayo-Castillo, David H. Sherman, David J. Miller> ;Journal of Biomolecular Screening. 2015 Jun 1
• 4 citations
  Manipulation of host factors optimizes the pathogenesis of western equine encephalitis virus infections in mice for antiviral drug development
  Pennelope K. Blakely, Phillip C. Delekta, David J. Miller, David N. Irani> ;Journal of Neurovirology. 2015 Feb 1
• 10 citations
  Novel Indole-2-Carboxamide Compounds Are Potent Broad-Spectrum Antivirals Active against Western Equine Encephalitis Virus In Vivo
  Phillip C. Delekta, Craig J. Dobry, Janice A. Sindac, Scott J. Barraza, Pennelope K. Blakely, Jianming Xiang, Paul D. Kirchhoff, Richard F. Keep, David N. Irani, Scott...> ;Journal of Virology. 2014 Oct 1
• 59 citations
  Discovery of potent broad spectrum antivirals derived from marine actinobacteria.
  Avi Raveh, Phillip C. Delekta, Craig J. Dobry, Weiping Peng, Pamela J. Schultz, Pennelope K. Blakely, Andrew W. Tai, Teatulohi Matainaho, David N. Irani, David H. Sher...> ;Plos One. 2013 Dec 5
• 22 citations
  Optimization of Novel Indole-2-carboxamide Inhibitors of Neurotropic Alphavirus Replication
  Janice A. Sindac, Scott J. Barraza, Craig J. Dobry, Jianming Xiang, Pennelope K. Blakely, David N. Irani, Richard F. Keep, David J. Miller, Scott D. Larsen> ;Journal of Medicinal Chemistry. 2013 Nov 27
• 19 citations
  Activation of the type I interferon pathway is enhanced in response to human neuronal differentiation.
  Jocelyn R. Farmer, Kate M. Altschaefl, K. Sue O'Shea, David J. Miller> ;Plos One. 2013 Mar 7
• 18 citations
  Novel inhibitors of neurotropic alphavirus replication that improve host survival in a mouse model of acute viral encephalitis.
  Janice A. Sindac, Bryan D. Yestrepsky, Scott J. Barraza, Kyle L. Bolduc, Pennelope K. Blakely, Richard F. Keep, David N. Irani, David J. Miller, Scott D. Larsen> ;Journal of Medicinal Chemistry. 2012 Apr 12
• 96 citations
  MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness.
  Qiong Wang, David J. Miller, Emily R. Bowman, Deepti R. Nagarkar, Dina Schneider, Ying Zhao, Marisa J. Linn, Adam M. Goldsmith, J. Kelley Bentley, Umadevi S. Sajjan, M...> ;Plos Pathogens. 2011 May 26
• 63 citations
  Human Neuronal Cells Possess Functional Cytoplasmic and TLR-Mediated Innate Immune Pathways Influenced by Phosphatidylinositol-3 Kinase Signaling
  Daniel Peltier, Allison Simms, Jocelyn R. Farmer, David J. Miller> ;Journal of Immunology. 2010 Jun 15
• 41 citations
  Role of cellular lipids in positive-sense RNA virus replication complex assembly and function.
  Kenneth A. Stapleford, David J. Miller> ;Viruses. 2010 Apr 29
• 43 citations
  Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in ...
  Kathryn M. Castorena, Kenneth A. Stapleford, David J. Miller> ;BMC Genomics. 2010 Mar 17
• 9 citations
  Restriction of Rift Valley Fever Virus Virulence in Mosquito Cells
  Valerie M. Vaughn, Cale C. Streeter, David J. Miller, Sonja R. Gerrard> ;Viruses. 2010 Feb 17
• 29 citations
  A Targeted Analysis of Cellular Chaperones Reveals Contrasting Roles for Heat Shock Protein 70 in Flock House Virus RNA Replication
  Spencer A. Weeks, William P. Shield, Chandan Sahi, Elizabeth A. Craig, Sabine Rospert, David J. Miller> ;Journal of Virology. 2010 Jan 1
• 190 citations
  Role of Double-Stranded RNA Pattern Recognition Receptors in Rhinovirus-Induced Airway Epithelial Cell Responses
  Qiong Wang, Deepti R. Nagarkar, Emily R. Bowman, Dina Schneider, Babina Gosangi, Jing Lei, Ying Zhao, Christina L. McHenry, Richai V. Burgens, David J. Miller, Umadevi...> ;Journal of Immunology. 2009 Dec 1
• 21 citations
  Mitochondrion-Enriched Anionic Phospholipids Facilitate Flock House Virus RNA Polymerase Membrane Association
  Kenneth A. Stapleford, Doron Rapaport, David J. Miller> ;Journal of Virology. 2009 May 1
• 27 citations
  Identification of Thieno[3,2-b]Pyrrole Derivatives as Novel Small Molecule Inhibitors of Neurotropic Alphaviruses
  Weiping Peng, Daniel Peltier, Martha J. Larsen, Paul D. Kirchhoff, Scott D. Larsen, Richard R. Neubig, David J. Miller> ;The Journal of Infectious Diseases. 2009 Apr 1
• 33 citations
  The Heat Shock Protein 70 Cochaperone YDJ1 Is Required for Efficient Membrane-Specific Flock House Virus RNA Replication Complex Assembly and Function in Saccharomyces...
  Spencer A. Weeks, David J. Miller> ;Journal of Virology. 2008 Feb 15
• 21 citations
  Maturation-dependent responses of human neuronal cells to western equine encephalitis virus infection and type I interferons.
  Kathryn M. Castorena, Daniel Peltier, Weiping Peng, David J. Miller> ;Virology. 2008 Mar 1
• 36 citations
  A functional heat shock protein 90 chaperone is essential for efficient flock house virus RNA polymerase synthesis in Drosophila cells.
  Kathryn M. Castorena, Spencer A. Weeks, Kenneth A. Stapleford, Amy M. Cadwallader, David J. Miller> ;Journal of Virology. 2007 Aug 15
• 226 citations
  Three-dimensional analysis of a viral RNA replication complex reveals a virus-induced mini-organelle.
  Benjamin G. Kopek, Guy Perkins, David J. Miller, Mark H. Ellisman, Paul Ahlquist> ;Plos Biology. 2007 Aug 14
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Journal Articles

• Manipulation of Host Factors Optimizes the Pathogenesis of Western Equine Encephalitis Virus Infections in Mice for Antiviral Drug Development  
  Blakely, P.K., Delekta, P.C., Miller, D.J., and Irani, D.N., J. Neurovirol, 1/1/2015
• Discovery of Anthranilamides as a Novel Class of Inhibitors of Neurotropic Alphavirus Replication  
  Barraza, S.J., Delekta, P.C., Sindac, J.A., Dobry, C.J., Xiang, J., Kirchhoff, P.D., Keep, R.F., Miller, D.J., and Larsen, S.D., Bioorg. Med. Chem, 1/1/2015
• The Combined Use of Alphavirus Replicons and Pseudoinfectious Particles for the Discovery of Antivirals Derived from Natural Products  
  Delekta, P.C., Raveh, A., Larsen, M.J., Sherman, D.H., and Miller, D.J., J. Biomolec. Screen, 1/1/2015
• Novel Indole-2-carboxamide Compounds Are Potent Broad Spectrum Antivirals Active against Western Equine Encephalitis Virus in Vivo  
  Delekta, P.C., Dobry, C.J., Sindac, J.A., Barraza, S.J., Blakely, P.K., Xiang, J., Kirchhoff, P.D., Keep, R.F., Irani, D.N., Larsen, S.D., and Miller, D.J., J. Virol, 1/1/2014
• Neurotropic Arboviruses Induce Interferon Regulatory Factor 3-mediated Neuronal Responses That Are Cytoprotective, Interferon-independent, and Inhibited by Western Equ...  
  Peltier, D.C., Lazear, H.M., Farmer, J.R., Diamond, M.S., and Miller, D.J., J. Virol, 1/1/2013
• Activation of the Type I Interferon Pathway Is Enhanced in Response to Human Neuronal Differentiation  
  Farmer, J.R., Altschaefl, K.M., O'Shea, K.S., and Miller, D.J., PLoS One, 1/1/2013
• Optimization of Novel Indole-2-carboxamide Inhibitors of Neurotropic Alphavirus Replication  
  Sindac, J.A., Barraza, S.J., Dobry, C.J., Xiang, J., Blakely, P.K., Irani, D.N., Keep, R.F., Miller, D.J., and Larsen, S.D., J. Med. Chem, 1/1/2013
• Discovery of Potent Broad Spectrum Antivirals Derived from Marine Actinobacteria  
  Raveh, A., Delekta, P.C., Dobry, C.J., Peng, W., Schultz, P.J., Blakely, P.K., Tai, A.W., Matainaho, T., Irani, D.N., Sherman, D.H., and Miller, D.J., PLoS One, 1/1/2013
• Discovery of Alphavirus Inhibitors Derived from Natural Products  
  Delekta, P.C., Raveh, A., Sherman, D.H., and Miller, D.J., Curr Topics Virology, 1/1/2013
• Novel Inhibitors of Neurotropic Alphavirus Replication That Improve Host Survival in a Mouse Model of Acute Viral Encephalitis  
  Sindac, J., Yestrepsky, B.D., Bolduc, K.L., Barraza, S.J., Bolduc, K.L, Blakely, P.K., Keep, R.F., Irani, D.N., Miller, D.J., and Larsen, S.D., J. Med. Chem., 1/1/2012
• MDA5 and TLR3 Initiate Pro-inflammatory Signaling Pathways Leading to Rhinovirus-induced Airway Inflammation and Hyperresponsiveness  
  Wang, Q, Miller, D.J., Bowman, E.R., Nagarkar, D.R., Schneider, D., Zhao, Y., Linn, M.J., Goldsmith, A.M., Bentley, J.K., Sajjan, U.S., Colonna, M., and Hershenson, M.B., PLoS Pathog, 1/1/2011
• Role of Cellular Lipids in Positive-sense RNA Virus Replication Complex Assembly and Function  
  Stapleford, K.A. and Miller, D.J., Viruses, 1/1/2010
• A Targeted Analysis of Cellular Chaperones Reveals Contrasting Roles for Heat Shock Protein 70 in Flock House Virus RNA Replication  
  Weeks, S.A., Shield, W.P., Sahi, C., Craig, E.A., Rospert, S., and Miller, D.J., J. Virol, 1/1/2010
• Restriction of Rift Valley Fever Virus Virulence in Mosquito Cells  
  Vaughn, V.M., Streeter, C.C., Miller, D.J., and Gerard, S.R., Viruses, 1/1/2010
• Complementary Transcriptomic, Lipidomic, and Targeted Functional Genetic Analyses in Cultured Drosophila Cells Highlight the Role of Glycerophospholipid Metabolism in ...  
  Castorena, K.M., Stapleford, K.A., and Miller, D.J., BMC Genomics, 1/1/2010
• Human Neuronal Cells Possess Functional Cytoplasmic and Toll-like Receptor-mediated Innate Immune Pathways Influenced by Phosphatidylinositol-3 Kinase Signaling  
  Peltier, D.C., Simms, A., Farmer, J.R., and Miller, D.J., J. Immunol, 1/1/2010
• The Identification of Thieno [3,2-b]pyrrole Derivatives as Novel Small Molecule Inhibitors of Neurotropic Alphaviruses  
  Peng, W., Peltier, D.C., Larsen, M.J., Kirchhoff, P.D., Larsen, S.D., Neubig, R.R., and Miller, D.J., J. Infect. Dis., 1/1/2009
• Mitochondrion-enriched Anionic Phospholipids Facilitate Flock House Virus RNA Polymerase Membrane Association  
  Stapleford, K.A., Rapaport, D., and Miller, D.J., J. Virol., 1/1/2009
• Role of Double-stranded RNA Pattern Recognition Receptors in Rhinovirus-induced Airway Epithelial Cell Responses  
  Wang, Q., Nagarkar, D.R., Bowman, E.R., Schneider, D., Gosangi, B., Lei, J., Zhao, Y., McHenry, C.L., Burgens, R.V., Miller, D.J., Sajjan, U., and Hershenson, M.B., J. Immunol, 1/1/2009
• The Heat Shock Protein 70 Co-chaperone YDJ1 Is Required for Membrane-specific Flock House Virus RNA Replication Complex Assembly and Function in Saccharomyces Cerevisiae  
  Weeks, S.A. and Miller, D.J., J. Virol, 1/1/2008
• A Functional Heat Shock Protein 90 Chaperone Is Essential for Efficient Flock House Virus RNA Polymerase Synthesis in Drosophila Cells  
  Castorena, K.M., Weeks, S.A., Stapleford, K.A., Cadwallader, A.M., and Miller, D.J., J. Virol, 1/1/2007
• Three-dimensional Analysis of a Viral RNA Replication Complex Reveals a Virus-induced Mini-organelle  
  Kopek, B.G., Perkins, G., Miller, D.J., Ellisman, M.H., and Ahlquist, P., PLoS Biology, 1/1/2007
• Detecting Protein-protein Interactions in Live Yeast by Flow Cytometry  
  Dye, B.T., Schell, K., Miller, D.J., and Ahlquist, P, Cytometry, 1/1/2005
• The Cellular Chaperone Heat Shock Protein 90 Facilitates Flock House Virus RNA Replication in Drosophila Cells  
  Kampmueller, K.M. and Miller, D.J., J. Virol, 1/1/2005
• In Vivo Self-interaction of Nodavirus RNA Replicase Protein a Revealed by Fluorescence Resonance Energy Transfer  
  Dye, B.T., Miller, D.J., and Ahlquist, P., J. Virol, 1/1/2005
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Books/Book Chapters

• Cell Biology and Pathology of Myelin 
  Chapter: The Repair of Central Nervous System Myelin. Cell Biology and Pharmacologic Action of Remyelination-promoting Autoantibodies 
  Page 253.0 - 264.0Hunter, S.F., Asakura, K., Miller, D.J., and Rodriguez, M.Editors: Juurlink et al.Plenum Press, New York1997