DavidBruceMountMD

PubMed

• 6 citations
  Genetic and Physiological Effects of Insulin-Like Growth Factor-1 (IGF-1) on Human Urate Homeostasis.
  Asim K Mandal, Megan P Leask, Nicholas A Sumpter, Hyon K Choi, Tony R Merriman, David B Mount> ;Journal of the American Society of Nephrology. 2023 Mar 1
• 15 citations
  Prescribing Patterns of Sodium-Glucose Cotransporter-2 Inhibitors in Patients with CKD: A Cross-Sectional Registry Analysis.
  Min Zhuo, Jiahua Li, Leo F Buckley, Sri Lekha Tummalapalli, David B Mount, David J R Steele, David J Lucier, Mallika L Mendu> ;Kidney360. 2022 Mar 31
• 5 citations
  Zoledronic Acid-Associated Fanconi Syndrome in Patients With Cancer.
  Ignacio Portales-Castillo, David B Mount, Sagar U Nigwekar, Elaine W Yu, Helmut G Rennke, Shruti Gupta> ;American Journal of Kidney Diseases. 2022 Oct 1
• Mutations in HOGA1 do Not Confer a Dominant Phenotype Manifesting as Kidney Stone Disease
  Roi Bar, Efrat Ben-Shalom, Mordechai Duvdevani, Ruth Belostotsky, Martin R. Pollak, David B. Mount, Ruth Bar-Gal, Ehud Gnessin, Shay Tzur, Gary C. Curhan, Yaacov Frish...> ;The Journal of Urology. 2021 May 1
• 7 citations
  The Shared Genetic Basis of Hyperuricemia, Gout, and Kidney Function
  Megan Leask, Nicholas A Sumpter, Alexa S Lupi, Ana I. Vazquez, Richard J. Reynolds, David B. Mount, Tony R. Merriman> ;Seminars in Nephrology. 2020 Nov 1
• 26 citations
  Molecular Pathophysiology of Uric Acid Homeostasis.
  Christopher Estiverne, Asim K. Mandal, David B. Mount> ;Seminars in Nephrology. 2020 Nov 1
• 1 citations
  Introduction: Gout and the Kidney.
  David B. Mount> ;Seminars in Nephrology. 2020 Nov 1
• 2 citations
  The Management of Gout in Renal Disease
  Christopher Estiverne, David B. Mount> ;Seminars in Nephrology. 2020 Nov 1
• 4 citations
  Incidence of Hyponatremia in Patients With Indwelling Peritoneal Catheters for Drainage of Malignant Ascites.
  Shruti Gupta, Maria Clarissa Tio, Emily D. Gutowski, Michael S. Stecker, Ashish Verma, Shveta S. Motwani, David B. Mount, Gearoid M. McMahon, Sushrut S. Waikar> ;JAMA Network Open. 2020 Oct 1
• 343 citations
  2020 American College of Rheumatology Guideline for the Management of Gout.
  John D FitzGerald, Nicola Dalbeth, Ted Mikuls, Romina Brignardello-Petersen, Gordon Guyatt, Aryeh M Abeles, Allan C Gelber, Leslie R Harrold, Dinesh Khanna, Charles Ki...> ;Arthritis & Rheumatology. 2020 Jun 1
• 161 citations
  2020 American College of Rheumatology Guideline for the Management of Gout.
  John D FitzGerald, Nicola Dalbeth, Ted Mikuls, Romina Brignardello-Petersen, Gordon Guyatt, Aryeh M Abeles, Allan C Gelber, Leslie R Harrold, Dinesh Khanna, Charles Ki...> ;Arthritis Care & Research. 2020 Jun 1
• 32 citations
  Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control
  James Boocock, Megan Leask, Yukinori Okada, Hirotaka Matsuo, Yusuke Kawamura, Yongyong Shi, Changgui Li, David B. Mount, Asim K. Mandal, Weiqing Wang, Murray Cadzow, A...> ;Human Molecular Genetics. 2020 Apr 15
• 4 citations
  "Pleurex Desalination" in Malignancy-related Ascites: A Novel Mechanism of Hyponatremia.
  Shruti Gupta, Gearoid M. McMahon, Shveta S. Motwani, David B. Mount, Sushrut S. Waikar> ;American Journal of Clinical Oncology. 2020 Jan 1
• 4 citations
  Genome-wide Association Study of 24-Hour Urinary Excretion of Calcium, Magnesium, and Uric Acid.
  Erin B. Ware, Jennifer A. Smith, Wei Zhao, Ron T. Ganesvoort, Gary C. Curhan, Martin R. Pollak, David B. Mount, Stephen T. Turner, Guotao Chen, Ronak Jagdeep Shah, Sha...> ;Mayo Clinic Proceedings. Innovations, Quality & Outcomes. 2019 Nov 22
• 14 citations
  Interaction Between ITM2B and GLUT9 Links Urate Transport to Neurodegenerative Disorders.
  Asim K. Mandal, David B. Mount> ;Frontiers in Physiology. 2019 Oct 22
• 27 citations
  Development of an electronic health record-based chronic kidney disease registry to promote population health management.
  Mallika L. Mendu, Salman Ahmed, Jason K. Maron, Sandhya Rao, Sreekanth K. Chaguturu, Megan F. May, Walter P. Mutter, Kelly A. Burdge, David J.R. Steele, David B. Mount...> ;BMC Nephrology. 2019 Mar 1
• 297 citations
  Hyperuricemia, Acute and Chronic Kidney Disease, Hypertension, and Cardiovascular Disease: Report of a Scientific Workshop Organized by the National Kidney Foundation.
  Richard J. Johnson, George L. Bakris, Claudio Borghi, Michel Chonchol, David L. Feldman, Miguel A. Lanaspa, Tony R. Merriman, Orson W. Moe, David B. Mount, Laura Gabri...> ;American Journal of Kidney Diseases. 2018 Jun 1
• 36 citations
  Population‐Specific Resequencing Associates the ATP‐Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Māori and Pacific Men
  Callum Tanner, James Boocock, Eli A. Stahl, Amanda Dobbyn, Asim K. Mandal, Murray Cadzow, Amanda Phipps-Green, Ruth Topless, Jennie Harré Hindmarsh, Lisa K. Stamp, Nic...> ;Arthritis & Rheumatology. 2017 May 31
• 42 citations
  Uricosuric targets of tranilast.
  Asim K. Mandal, Adriana Mercado, Andria Foster, Kambiz Zandi-Nejad, David B. Mount> ;Pharmacology Research & Perspectives. 2017 Feb 6
• 7 citations
  Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8).
  Adriana M. López-Barradas, Tania González-Cid, Norma Vázquez, Marisol Gavi-Maza, Adriana Reyes-Camacho, Laura A. Velázquez-Villegas, Victoria Ramírez, Kambiz Zandi-Nej...> ;American Journal of Physiology. Cell Physiology. 2016 Nov 1
• 22 citations
  Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy.
  , , , , , , , , , , , , , , , , > ;Kidney International Reports. 2016 Sep 1
• 5 citations
  Cortical gene expression: prognostic value for seizure outcome following temporal lobectomy and amygdalohippocampectomy.
  Matthew J. Gallek, Jesse Skoch, Tracy Ansay, Mandana Behbahani, David B. Mount, Ann Manziello, Marlys H. Witte, Michael Bernas, David M. Labiner, Martin E. Weinand> ;Neurogenetics. 2016 Jun 2
• 4 citations
  An electronic alert to decrease Kayexalate ordering.
  David E. Leaf, Xingxing S. Cheng, Jason L. Sanders, Mallika L. Mendu, Gordon D. Schiff, David B. Mount, Hasan Bazari> ;Renal Failure. 2016 May 17
• 51 citations
  Diagnosis and treatment of hypernatremia.
  Saif A. Muhsin, David B. Mount> ;Best Practice & Research. Clinical Endocrinology & Metabolism. 2016 Mar 1
• 287 citations
  The Molecular Physiology of Uric Acid Homeostasis
  Asim K. Mandal, David B. Mount> ;Annual Review of Physiology. 2015 Feb 10
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Journal Articles

• An electronic alert to decrease Kayexalate ordering  
  Leaf D.E., Cheng X.S., Sanders J.L., Mendu M., Schiff G.D., Mount D.B., Bazari H., Ren Fail., 1/1/2016
• Diagnosis and treatment of hypernatremia  
  Muhsin S.A., Mount D.B., Best Pract Res Clin Endocrinol Metab, 1/1/2016
• The molecular physiology of uric acid homeostasis  
  Mandal A.K., Mount D.B., Annu Rev Physiol, 1/1/2015
• Conformational change in transfer RNA is an early indicator of acute cellular damage  
  Mishima E., Inoue C., Saigusa D., Inoue R, Ito K., Suzuki Y., Jinno D., Tsukui Y., Akamatsu Y., Araki M., Araki K., Shimizu R., Shinke H., Suzuki T., Takeuchi Y., Shim..., J Am Soc Nephrol, 1/1/2014
• Glycosylation regulates the function and membrane localization of KCC4  
  Weng T.Y., Chiu W.T., Liu H.S., Cheng H.C., Shen M.R., Mount D.B., Chou C.Y., Biochim Biophys Acta, 1/1/2013
• Pregnancy-Associated Polyuria in Familial Renal Glycosuria  
  Toka H.R., Yang J., Zera C.A., Duffield J.S., Pollak M.R., Mount D.B., Am J Kidney Dis, 1/1/2013
• The Kidney in Hyperuricemia and Gout  
  Mount D.B., Current Opinion in Nephrology, 1/1/2013
• The independent association between parathyroid hormone levels and hyperuricemia: a national population study  
  Hui J, Choi JW, Mount D.B., Zhu Y, Zhang Y, Choi HK, Arthritis Res Ther, 1/10/2012
• Hyperpolarizing GABAergic Transmission Requires the KCC2 C-terminal ISO Domain  
  Acton B.A., Mahadevan V., Mercado A., Uvarov P., Ding Y., Pressey J., Airaksinen M.S., Mount D.B., Woodin, M.A., J Neuroscience, 1/1/2012
• Kidney-specific calcium-sensing receptor deficient mice display PTH-independent hypocalciuria  
  Toka H.R., Al-Romaih K., Koshy J.M., DiBartolo III, S., Kos C.H., Quinn S.J., Curhan G.C., Mount D.B., Brown E.M., Pollak M.R., J Am Soc Nephrol, 1/1/2012
• Update on the genetics and hyperuricemia of gout  
  Reginato A.M., Mount D.B., Yang, I., and Choi H.K., Nature Rheumatol, 1/1/2012
• K-Cl Cotransporter Gene Expression during Human and Murine Erythroid Differentiation  
  Pan D., Kalfa T.A., Wang D., Risinger M., Crable S., Ottlinger A., Chandra S., Mount D.B., Hübner C.A., Franco R.S., Joiner C.H., J Biol Chem, 1/1/2011
• Pickard GE Cell-type specific distribution of chloride transporters in the rat suprachiasmatic nucleus  
  Belenky M.A., Sollars P.J., Mount D.B., Alper S.L., Yarom Y., Pickard G.E., Neuroscience, 1/1/2010
• Slc26A9 is a highly electrogenic and Na+-transporting anion exchanger  
  Chang, M.-H., Plata, C., Zandi-Nejad, K., Sussman, C.R., Mercado, A,, Mount, D.B., and Romero, M.F., J. Membr. Biol., 1/1/2009
• Hyponatremia: introduction  
  Mount D.B., Seminars in Nephrology, 1/1/2009
• Hyponatremia and the brain; both culprit and victim  
  Mount D.B., Seminars in Nephrology, 1/1/2009
• Hyponatremia: case vignettes  
  Mount D.B., Krahn T., Seminars in Nephrology, 1/1/2009
• Splicing a kinase and the regulation of salt transport  
  Mount D.B., J. Am. Soc. Nephrol., 1/1/2009
• Over-expression of KCC2 perturbs neurogenesis  
  Reynolds, A., Brustein, E., Liao, M., Mercado, A., Babilonia, E., M., Mount, D.B., Drapeau, P., J Neurosci, 1/1/2008
• Roles of the cation-chloride cotransporters in neurological disease  
  Kahle K.T., Staley K.J., Nahed B.V., Gamba G., Hebert S.C., Lifton R.P., Mount D.B., Nature Clinical Practice Neurology, 1/1/2008
• Zebrafish Slc5a12 encodes an electroneutral sodium monocarboxylate transporter (SMCTn): A comparison to the electrogenic SMCT (SMCTe/Slc5a8)  
  Plata, C., Sussman, C.R., Sindic, A., Liang, J.O., Mount, D.B., Josephs, Z.M., Chang, M.H. & Romero, M.F., J Biol Chem, 1/1/2007
• Collectrin and the kidney  
  Mount D.B., Current Opinion in Nephrology, 1/1/2007
• Renal physiology of SLC26 anion exchangers  
  Sindic A., Chang M.H., Mount D.B. & Romero M.F., Curr Opin Nephrol Hypertens, 1/1/2007
• Constitutive activity of the neuronal K-Cl cotransporter KCC2 is conferred by a 15-residue C-terminal domain  
  Mercado A, Zandi-Nejad K, Broumand V, Enck AH, and Mount, D.B., J. Biol. Chem., 1/1/2006
• WNK3 regulates a novel kinase/phosphatase pathway that bypasses the tonicity requirement for K-Cl cotransporter activation  
  Heros, P., Kahle, K.T., Rinehart, J., Bobadilla, N.A., Vazquez, N., san Cristobal, P., Mount, D.B., Lifton, R.P., Hebert, S.C., Gamba, G., Proc. Natl. Acad. Sci., 1/1/2006
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Books/Book Chapters

• Schrier's Diseases of the Kidney 
  Chapter: "Tubular Potassium Transport" 
  Page 194 - 213Mount D.B.Wolters Kluwer2013
• UpToDate 
  Chapter: "Treatment and prevention of hyperkalemia" 
  Mount D.BEditors: Basow, D.S..Waltham, MA2012
• UpToDate 
  Chapter: "Causes of hypokalemia" 
  Mount D.BEditors: Basow, D.S..Waltham, MA2012
• UpToDate 
  Chapter: "Clinical manifestations and treatment of hypokalemia" 
  Mount D.BEditors: Basow, D.S..Waltham, MA2012
• UpToDate 
  Chapter: "Potassium and hypertension" 
  Kaplan N.M., Mount D.B.Editors: Basow, D.S..Waltham, MA2012
• UpToDate 
  Chapter: "Causes and evaluation of hyperkalemia" 
  Mount D.B.Editors: Basow, D.S..Waltham, MA2012
• UpToDate 
  Chapter: "Hypouricemia; Causes and clinical significance" 
  Mount D.B.Editors: Basow, D.S..Waltham, MA2012
• Harrison's Handbook of Internal Medicine 
  Chapter: Renal 
  Mount D.B.McGraw HillEdition 18th,2012
• Core Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance 
  Chapter: "Disorders of Calcium, Magnesium, and Phosphate Homeostasis" 
  Page 103 - 146Hariri A., Mount D.B., Rastegar, A.Editors: Mount D.B., Sayegh M.H., Singh A.K..Springer2012
• Core Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance 
  Chapter: "The Physiology of Water Homeostasis" 
  Page 1 - 28Sands J.M., Mount D.B., and Layton H.E.Editors: Mount D.B., Sayegh M.H., Singh A.K..Springer2012
• Core Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance 
  Chapter: "Case Studies in Electrolyte and Acid-Base Disorders" 
  Page 327 - 362Mount D.B.Editors: Mount D.B., Sayegh M.H., Singh A.K..Springer2012
• The Kidney 
  Chapter: "Transport of Sodium, Chloride, and Potassium" 
  Page 158 - 201Mount D.B.Editors: Brenner and Rector.W.B. Saunders & CompanyEdition 9th,2011
• Harrison's Principles of Internal Medicine 
  Chapter: "Fluid and Electrolyte Disturbances" 
  Page 341 - 359Mount D.B.McGraw HillEdition 18th,2010
• Harrison's Principles of Internal Medicine 
  Chapter: "Examples of Fluid & Electrolyte Imbalances and of Acid-Base Disturbances: Interpretation and Management - Case Discussions" 
  Mount D.B. and Dubose T.McGraw HillEdition 18th,2010
• Harrison's Handbook of Internal Medicine 
  Chapter: Renal, Acid-base, Electrolyte disorder 
  Mount D.B.McGraw HillEdition 17th,2009
• The Kidney 
  Chapter: "Transport of Inorganic Solutes: Sodium, Potassium, Calcium, Magnesium, and Phosphate" 
  Yu A.S.L. and Mount D.B.Editors: Brenner and Rector.W.B. Saunders & CompanyEdition 8th,2008
• The Molecular and Genetic Basis of Renal Disease 
  Mount D.B. and Pollak M.P.W.B. Saunders & CompanyEdition 1st,2007
• The Molecular and Genetic Basis of Renal Disease 
  Chapter: "The Impact of Molecular Genetics on Nephrology" 
  Page 1 - 2Mount D.B. and Pollak M.P.Editors: Mount, D.B. and Pollak M.P..W.B. Saunders & CompanyEdition 1st,2007
• The Molecular and Genetic Basis of Renal Disease 
  Chapter: "Hereditary Disorders of the Proximal Nephron" 
  Page 201 - 228Kwon C.Y. and Mount D.B.Editors: Mount, D.B. and Pollak M.P..W.B. Saunders & CompanyEdition 1st,2007
• The Kidney 
  Chapter: "Disorders of Potassium Balance" 
  Page 997 - 1040Mount D.B. and Zandi-Nejad K.Editors: Brenner and Rector.W.B. Saunders & CompanyEdition 7th,2004
• The Kidney 
  Chapter: "The Molecular Basis of Solute Transport" 
  Page 261 - 308Hediger M., Rolfs A., Romero M.F., and Mount, D.B.Editors: Brenner and Rector.W.B. Saunders & CompanyEdition 7th,2004
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Lectures

• "Genetics, GWAS and Uric acid" 
  Atlanta, GA - 1/22/2016
• "Acidosis" 
  1/1/2016
• "Therapeutic Plasma Exchange" 
  1/1/2016
• "Light Chain Gang" 
  West Roxbury VA Medical Center - 1/22/2015
• "A Bright Signal" 
  West Roxbury VA Medical Center - 1/10/2015
• "Integumentary My Dear Watson" 
  West Roxbury VA Medical Center - 1/8/2015
• "Glut9 and Hyperuricemia" 
  San Francisco, CA - 1/6/2015
• "Molecular Pathophysiology of Renal Reabsorptive Urate Transport" 
  Paris, France - 1/5/2015
• "Pathophysiology Conference" 
  1/26/2014
• "Paraproteinemic Renal Diseases" 
  1/22/2014
• "Shocking Developments" 
  West Roxbury VA Medical Center - 1/17/2014
• "Gout, Uric Acid, and the Kidney" and "Cases from Renal Grand Rounds at the Brigham" 
  Mexico City, Mexico - 1/3/2014
• "Morbidity and Mortality Conference" 
  1/28/2013
• "Challenging Outpatient Cases of Electrolyte Abnormalities" 
  1/8/2013
• "Hard To Swallow" 
  West Roxbury VA Medical Center - 1/31/2012
• "How Many Antibodies Are In Attendance Today" 
  West Roxbury VA Medical Center - 1/27/2012
• "Gout, Uric Acid, and the Kidney" 
  Brigham and Women's Hospital - 1/24/2012
• "Rough Air" 
  West Roxbury VA Medical Center - 1/22/2012
• "The Long Goodbye" 
  West Roxbury VA Medical Center - 1/19/2012
• "A Tight Spot" 
  West Roxbury VA Medical Center - 1/13/2012
• "Hyponatremia and Hypernatremia" 
  1/7/2012
• "Hypokalemia and Hyperkalemia" 
  1/7/2012
• "A Renal Stress Test" 
  West Roxbury VA Medical Center - 1/25/2011
• "A Bus Driver with Joint Aches" 
  West Roxbury VA Medical Center - 1/20/2011
• "Update on Renal Uric Acid Transport" 
  Boston, MA - 1/16/2011
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Other

• New Developments in Potassium Disorders 
  Mount, D.B., NephSAP (invited editorial)
• Potassium and hypertension 
  Mount DB, Kaplan NM
  http://www.uptodate.com/contents/potassium-and-hypertension
  UpToDate, Wolters Kluwer Health - 2012-04-27
• Hypouricemia: Causes and clinical significance 
  Mount DB
  http://www.uptodate.com/contents/hypouricemia-causes-and-clinical-significance
  UpToDate, Wolters Kluwer Health - 2012-09-06
• Causes and evaluation of hyperkalemia in adults 
  Mount DB
  http://www.uptodate.com/contents/causes-and-evaluation-of-hyperkalemia-in-adults
  UpToDate, Wolters Kluwer Health - 2013-01-14
• Causes of hypokalemia 
  Mount DB
  http://www.uptodate.com/contents/causes-of-hypokalemia
  UpToDate, Wolters Kluwer Health - 2012-11-20
• Clinical manifestations and treatment of hypokalemia 
  Mount DB
  http://www.uptodate.com/contents/clinical-manifestations-and-treatment-of-hypokalemia
  UpToDate, Wolters Kluwer Health - 2013-01-30
• Clinical manifestations of hyperkalemia in adults 
  Mount DB
  http://www.uptodate.com/contents/clinical-manifestations-of-hyperkalemia-in-adults
  UpToDate, Wolters Kluwer Health - 2012-04-20
• Treatment and prevention of hyperkalemia in adults 
  Mount DB
  http://www.uptodate.com/contents/treatment-and-prevention-of-hyperkalemia-in-adults
  UpToDate, Wolters Kluwer Health - 2012-10-23
• Hyponatremia and hyperkalemia in adrenal insufficiency 
  Mount DB
  http://www.uptodate.com/contents/hyponatremia-and-hyperkalemia-in-adrenal-insufficiency
  UpToDate, Wolters Kluwer Health - 2013-02-12
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