David R Rubinow MD
Professor and Chair of Psychiatry; Professor of Medicine; Director, UNC Innovation and Health Care System Transformation; and Director, UNC Center for Women’s Mood Disorders
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101 Manning DrChapel Hill, NC 27514
Phone+1 919-966-8596
Fax+1 919-843-5515
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Education & Training
National Institutes of Health Clinical CenterResidency, Psychiatry, 1979 - 1981
Yale-New Haven Medical CenterResidency, Psychiatry, 1976 - 1979
Uconn School Of MedicineClass of 1975
Certifications & Licensure
NC State Medical License 2006 - 2027
MD State Medical License 1980 - 2007
DC State Medical License 1982 - 2006
American Board of Psychiatry and Neurology Psychiatry
Awards, Honors, & Recognition
- Elected Member Institute of Medicine, 2011
Clinical Trials
Publications & Presentations
PubMed
- 1 citationsSustained benefits of closed-loop transcranial alternating current stimulation (CL-tACS) on depression: a 12-week open-label clinical trial.Tobias Schwippel, Francesca Pupillo, Zachary W Feldman, Christopher Walker, Leah Townsend
European Archives of Psychiatry and Clinical Neuroscience. 2026-08-01 - Esr1-dependent signaling and transcriptional maturation in the medial preoptic area of the hypothalamus shape the development of mating behavior during adolescence.Koichi Hashikawa, Yoshiko Hashikawa, Brandy Briones, Kentaro K Ishii, Yuejia Liu
Elife. 2026-06-19 - Inhaled Mebufotenin (GH001) for Adult Patients With Postpartum Depression: A Phase 2a Open-Label Clinical Trial.Martin Johnson, Pau Aceves Baldo, Emilio Arbe, Brian Brennan, Sem E Cohen
The Journal of Clinical Psychiatry. 2026-06-03
Journal Articles
- Safety of Estradiol Treatment in Perimenopausal Asymptomatic Women—ReplyDavid Rubinow, MD, JAMA
- Sex Differences and the Neurobiology of Affective DisordersDavid Rubinow, MD, Nature
Authored Content
- Progesterone and Plasma Metabolites in Women with and in Those Without Premenstrual Dysphoric DisorderSeptember 2018
- Progesterone and Plasma Metabolites in Women with and in Those Without Premenstrual Dysphoric DisorderSeptember 2018
- F122. The Neuronal Stem Cell Transcriptome of Premenstrual Dysphoric DisorderApril 2018
Press Mentions
FDA Grants Breakthrough Device Designation for Non-Invasive Brain Stimulation Device to Treat Major Depressive DisorderMarch 10th, 2025- Personalized Brain Stimulation Significantly Decreases Depression SymptomsAugust 27th, 2024
FDA Approves ZULRESSO™ (Brexanolone) Injection for Postpartum Depression Following Three Clinical Trials Led by UNC ResearcherMarch 20th, 2019
Grant Support
- Postdoctoral Training in Reproductive Mood DisordersUNIV OF NORTH CAROLINA CHAPEL HILL2012–2028
- Stress-stimulated immune profiles and cardiometabolic risk during the menopausal transitionUNIV OF NORTH CAROLINA CHAPEL HILL2022–2025
- Depression, Estrogen Replacement, And Cardiovascular Health In The PerimenopauseNational Institute Of Mental Health2010–2012
- Continuous OC Treatment In PMDD: Steroid Hormone MechanismsNational Institute Of Mental Health2008–2011
- Menstrually Related Mood Disorders Screening ProtocolNational Center For Research Resources2008
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