DavidShermanMD

PubMed

• 4 citations
  Recent advances in hapalindole-type cyanobacterial alkaloids: biosynthesis, synthesis, and biological activity.
  Robert M. Hohlman, David H. Sherman> ;Natural Product Reports. 2021 Sep 23
• 6 citations
  Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
  Elinor Breiner-Goldstein, Z. Eyal, Donna Matzov, Y. Halfon, Giuseppe Cimicata, Moti Baum, Assaf Rokney, Analia V. Ezernitchi, Andrew N. Lowell, Jennifer J. Schmidt, Ha...> ;Nucleic Acids Research. 2021 Sep 20
• 1 citations
  Engineering Sequence and Selectivity of Late-Stage C-H Oxidation in the MycG Iterative Cytochrome P450.
  Yohei Iizaka, Ryusei Arai, Akari Takahashi, Mikino Ito, Miho Sakai, Atsushi Fukumoto, David H. Sherman, Yojiro Anzai> ;Journal of Industrial Microbiology & Biotechnology. 2021 Sep 20
• 3 citations
  Identification of a New Antimicrobial, Desertomycin H, Utilizing a Modified Crowded Plate Technique.
  Osama G. Mohamed, Sadaf Dorandish, Rebecca Lindow, Megan Steltz, Ifrah Shoukat, Maira Shoukat, Hussein Chehade, Sara Baghdadi, Madelaine McAlister-Raeburn, Asad Kamal,...> ;Marine Drugs. 2021 Jul 27
• 10 citations
  Biosynthetic Cyclization Catalysts for the Assembly of Peptide and Polyketide Natural Products
  Maria L. Adrover-Castellano, Jennifer J. Schmidt, David H. Sherman> ;Chemcatchem. 2021 May 7
• 12 citations
  Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase.
  Edward Kalkreuter, Kyle S Bingham, Aaron M Keeler, Andrew N. Lowell, Jennifer J. Schmidt, David H. Sherman, Gavin J. Williams> ;Nature Communications. 2021 Apr 13
• 2 citations
  Structural diversification of hapalindole and fischerindole natural products via cascade biocatalysis.
  Robert M. Hohlman, Sean A. Newmister, Jacob N. Sanders, Yogan Khatri, Shasha Li, Nikki R. Keramati, Andrew N. Lowell, Kendall N. Houk, David H. Sherman> ;ACS Catalysis. 2021 Apr 5
• 6 citations
  An overview of the cytochrome P450 enzymes that catalyze the same-site multistep oxidation reactions in biotechnologically relevant selected actinomycete strains
  Yohei Iizaka, David H. Sherman, Yojiro Anzai> ;Applied Microbiology and Biotechnology. 2021 Mar 12
• 7 citations
  Co-cultivation of microbial sub-communities in microfluidic droplets facilitates high-resolution genomic dissection of microbial ‘dark matter’
  James Y. Tan, Sida Wang, Gregory J. Dick, Vincent B. Young, David H. Sherman, Mark A. Burns, Xiaoxia Nina Lin> ;Integrative Biology. 2020 Nov 18
• 9 citations
  Molecular Basis of Iterative C─H Oxidation by TamI, a Multifunctional P450 monooxygenase from the Tirandamycin Biosynthetic Pathway.
  Sean A. Newmister, Kinshuk Raj Srivastava, Rosa V. Espinoza, Kersti Caddell Haatveit, Yogan Khatri, Rachel M. Martini, Marc Garcia-Borràs, Larissa M. Podust, Kendall N...> ;ACS Catalysis. 2020 Nov 4
• 9 citations
  Computational-Based Mechanistic Study and Engineering of Cytochrome P450 MycG for Selective Oxidation of 16-Membered Macrolide Antibiotics.
  Song Yang, Matthew D. DeMars, Jessica M. Grandner, Noelle M. Olson, Yojiro Anzai, David H. Sherman, Kendall N. Houk> ;Journal of the American Chemical Society. 2020 Oct 8
• 12 citations
  Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes.
  Mark M. Painter, Gretchen Zimmerman, Madeline Merlino, Andrew Robertson, Valeri H. Terry, Xuefeng Ren, Megan McLeod, Lyanne Gomez-Rodriguez, Kirsten A Garcia, Jolie A....> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Sep 22
• 9 citations
  Flavin‐Dependent Monooxygenases NotI and NotI′ Mediate Spiro‐Oxindole Formation in Biosynthesis of the Notoamides
  Amy E. Fraley, Hong T. Tran, Samantha P. Kelly, Sean A. Newmister, Ashootosh Tripathi, Hikaru Kato, Sachiko Tsukamoto, Lei Du, Shengying Li, Robert M. Williams, David ...> ;Chembiochem. 2020 Sep 1
• 25 citations
  Structure and Function of NzeB, a Versatile C-C and C-N Bond-Forming Diketopiperazine Dimerase.
  Vikram V. Shende, Yogan Khatri, Sean A. Newmister, Jacob N. Sanders, Petra Lindovska, Fengan Yu, Tyler J. Doyon, Justin Kim, K. N. Houk, Mohammad Movassaghi, David H. ...> ;Journal of the American Chemical Society. 2020 Aug 12
• 6 citations
  Probing Selectivity and Creating Structural Diversity Through Hybrid Polyketide Synthases
  Aaron A. Koch, Jennifer J. Schmidt, Andrew N. Lowell, Douglas A. Hansen, Katherine M. Coburn, Joseph A. Chemler, David H. Sherman> ;Angewandte Chemie. 2020 Aug 3
• 1 citations
  Exploring the molecular basis for selective C–H functionalization in plant P450s
  Rosa V. Espinoza, David H. Sherman> ;Synthetic and Systems Biotechnology. 2020 Jun 9
• 32 citations
  Fungal-derived brevianamide assembly by a stereoselective semipinacolase.
  Ying Ye, Lei Du, Xingwang Zhang, Sean A. Newmister, Morgan McCauley, Juan V. Alegre-Requena, Wei Zhang, Shuai Mu, Atsushi Minami, Amy E. Fraley, Maria L. Adrover-Caste...> ;Nature Catalysis. 2020 May 18
• 16 citations
  Multicomponent Microscale Biosynthesis of Unnatural Cyanobacterial Indole Alkaloids
  Yogan Khatri, Robert M. Hohlman, Johnny Mendoza, Shasha Li, Andrew N. Lowell, Haruichi Asahara, David H. Sherman> ;ACS Synthetic Biology. 2020 May 7
• 13 citations
  Enzyme evolution in fungal indole alkaloid biosynthesis
  Amy E. Fraley, David H. Sherman> ;The FEBS Journal. 2020 Apr 1
• 2 citations
  Control of Stereoselectivity in Diverse Hapalindole Metabolites is Mediated by Cofactor-Induced Combinatorial Pairing of Stig Cyclases
  Shasha Li, Sean A. Newmister, Andrew N. Lowell, Jiachen Zi, Callie R. Chappell, Fengan Yu, Robert M. Hohlman, Jimmy Orjala, Robert M. Williams, David H. Sherman> ;Angewandte Chemie. 2020 Feb 13
• 21 citations
  Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway
  Amy E. Fraley, K. Caddell Haatveit, Ying Ye, Samantha P. Kelly, Sean A. Newmister, Fengan Yu, Robert M. Williams, Janet L. Smith, K. N. Houk, David H. Sherman> ;Journal of the American Chemical Society. 2020 Feb 5
• 6 citations
  DDAP: docking domain affinity and biosynthetic pathway prediction tool for type I polyketide synthases.
  Tingyang Li, Ashootosh Tripathi, Fengan Yu, David H. Sherman, Arvind Rao> ;Bioinformatics. 2020 Feb 1
• 7 citations
  Adipostatins E-J, new potent antimicrobials identified as inhibitors of coenzyme-A biosynthesis
  Lyanne Gomez-Rodriguez, Pamela J. Schultz, Giselle Tamayo-Castillo, Garry D. Dotson, David H. Sherman, Ashootosh Tripathi> ;Tetrahedron Letters. 2020 Jan 30
• 3 citations
  Stereoselective Synthesis of Baulamycin A
  Jonathan R Thielman, David H. Sherman, Robert M. Williams> ;The Journal of Organic Chemistry. 2020 Jan 23
• 10 citations
  A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs.
  Jennifer J. Schmidt, Yogan Khatri, Scott I Brody, Catherine Zhu, Halina Pietraszkiewicz, Frederick A. Valeriote, David H. Sherman> ;ACS Chemical Biology. 2020 Feb 3
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