DavidAnthonyStoltzMD

PubMed

• 1 citations
  Effects of Tham Nasal Alkalinization on Airway Microbial Communities: A Pilot Study in Non-CF and CF Adults.
  Zachary M. Holliday, Janice L. Launspach, Lakshmi Durairaj, Pradeep K. Singh, Joseph Zabner, David A. Stoltz> ;The Annals of Otology, Rhinology, and Laryngology. 2021 Oct 21
• 4 citations
  Early intrahepatic duct defects in a cystic fibrosis porcine model.
  Keyan Zarei, David K. Meyerholz, David A. Stoltz> ;Physiological Reports. 2021 Jul 1
• 7 citations
  Early Lung Disease Exhibits Bacteria-Dependent and -Independent Abnormalities in Cystic Fibrosis Pigs.
  Drake C. Bouzek, Mahmoud H. Abou Alaiwa, Ryan J. Adam, Alejandro A. Pezzulo, Leah R. Reznikov, Daniel P. Cook, Maria I Aguilar Pescozo, Patrick Ten Eyck, Chaorong Wu, ...> ;American Journal of Respiratory and Critical Care Medicine. 2021 Sep 20
• 22 citations
  Inflammatory cytokines TNF-α and IL-17 enhance the efficacy of cystic fibrosis transmembrane conductance regulator modulators
  Tayyab Rehman, Philip H. Karp, Ping Tan, Brian J Goodell, Alejandro A. Pezzulo, Andrew L Thurman, Ian M. Thornell, S.L. Durfey, Michael E. Duffey, David A. Stoltz, Edw...> ;The Journal of Clinical Investigation. 2021 Aug 16
• 3 citations
  Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4.
  Oliver G Chen, Steven E Mather, Christian M Brommel, Bradley A. Hamilton, Annie Ehler, Raul Villacreses, Reda E. Girgis, Mahmoud H. Abou Alaiwa, David A. Stoltz, Josep...> ;Cells. 2021 Apr 25
• 7 citations
  V-Type ATPase Mediates Airway Surface Liquid Acidification in Pig Small Airway Epithelial Cells.
  Xiaopeng Li, Raul Villacreses, Ian M. Thornell, Julio Noriega, Steven E Mather, Christian M Brommel, Lin Lu, Adam Zabner, Annie Ehler, David K. Meyerholz, David A. Sto...> ;American Journal of Respiratory Cell and Molecular Biology. 2021 Mar 31
• 46 citations
  Sustained Coinfections with Staphylococcus aureus and Pseudomonas aeruginosa in Cystic Fibrosis
  Anthony J. Fischer, Sachinkumar B. Singh, Mason M LaMarche, Lucas J Maakestad, Zoe E Kienenberger, Tahuanty Pena, David A. Stoltz, Dominique H. Limoli> ;American Journal of Respiratory and Critical Care Medicine. 2021 Feb 1
• 17 citations
  Lack of airway submucosal glands impairs respiratory host defenses
  Lynda S. Ostedgaard, Margaret P. Price, Kristin M. Whitworth, Mahmoud H. Abou Alaiwa, Anthony J. Fischer, Akshaya Warrier, Melissa Samuel, Lee D. Spate, Patrick D Alle...> ;Elife. 2020 Oct 7
• 3 citations
  Detargeting Lentiviral-Mediated CFTR Expression in Airway Basal Cells Using miR-106b.
  Soon H. Choi, Rosie E Reeves, Guillermo S Romano Ibarra, Thomas J. Lynch, Weam Shahin, Zehua Feng, Grace N Gasser, Michael C. Winter, T. Idil Apak Evans, Xiaoming Liu,...> ;Genes. 2020 Oct 6
• 19 citations
  Acidic Submucosal Gland pH and Elevated Protein Concentration Produce Abnormal Cystic Fibrosis Mucus.
  Yuliang Xie, Lin Lu, Xiao Xiao Tang, Thomas O. Moninger, Tony Jun Huang, David A. Stoltz, Michael J. Welsh> ;Developmental Cell. 2020 Aug 24
• 12 citations
  Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model.
  Keyan Zarei, Mallory R. Stroik, Nicholas D. Gansemer, Andrew L Thurman, Lynda S. Ostedgaard, Sarah E. Ernst, Ian M. Thornell, Linda S. Powers, Alejandro A. Pezzulo, Da...> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 2020 Jul 27
• 9 citations
  Tissue traction microscopy to quantify muscle contraction within precision-cut lung slices.
  Sumati Ram-Mohan, Yan Bai, Niccole Schaible, Allen J. Ehrlicher, Daniel P. Cook, Béla Suki, David A. Stoltz, Julian Solway, Xingbin Ai, Ramaswamy Krishnan> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2020 Feb 1
• 91 citations
  Cystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related conditions.
  Aaron C. Miller, Alejandro P. Comellas, Douglas B. Hornick, David A. Stoltz, Joseph E. Cavanaugh, Alicia K. Gerke, Michael J. Welsh, Joseph Zabner, Philip M. Polgreen> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Jan 21
• 31 citations
  A Novel AAV-mediated Gene Delivery System Corrects CFTR Function in Pigs.
  Ashley L. Cooney, Ian M. Thornell, Brajesh K. Singh, Viral Shah, David A. Stoltz, Paul B. McCray, Joseph Zabner, Patrick L. Sinn> ;American Journal of Respiratory Cell and Molecular Biology. 2019 Nov 27
• 32 citations
  Mucus strands from submucosal glands initiate mucociliary transport of large particles
  Anthony J. Fischer, Maria I Pino-Argumedo, Brieanna M Hilkin, Cullen R Shanrock, Nicholas D. Gansemer, Anna L Chaly, Keyan Zarei, Patrick D Allen, Lynda S. Ostedgaard,...> ;JCI Insight. 2019 Jan 10
• 13 citations
  Mucociliary Transport in Healthy and Cystic Fibrosis Pig Airways.
  Yuliang Xie, Lynda S. Ostedgaard, Mahmoud H. Abou Alaiwa, Lin Lu, Anthony J. Fischer, David A. Stoltz> ;Annals of the American Thoracic Society. 2018 Nov 15
• 12 citations
  CFTR Heterozygotes Are at Increased Risk of Respiratory Infections: A Population-Based Study
  Philip M. Polgreen, Grant D. Brown, Douglas B. Hornick, Ferhaan Ahmad, Barry London, David A. Stoltz, Alejandro P. Comellas> ;Open Forum Infectious Diseases. 2018 Nov 1
• 17 citations
  Glycogen depletion can increase the specificity of mucin detection in airway tissues
  David K. Meyerholz, Amanda P. Beck, J. Adam Goeken, Mariah R. Leidinger, Georgina K. Ofori-Amanfo, Hannah C. Brown, Thomas R. Businga, David A. Stoltz, Leah R. Rezniko...> ;BMC Research Notes. 2018 Oct 25
• 33 citations
  Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus.
  Ashley L. Cooney, Brajesh K. Singh, Laura I. Marquez Loza, Ian M. Thornell, Camilla E Hippee, Linda S. Powers, Lynda S. Ostedgaard, David K. Meyerholz, Chris Wohlford-...> ;Nucleic Acids Research. 2018 Oct 12
• 15 citations
  Ivacaftor-induced sweat chloride reductions correlate with increases in airway surface liquid pH in cystic fibrosis
  Mahmoud H. Abou Alaiwa, Jan L. Launspach, B. Grogan, S. Carter, Joseph Zabner, David A. Stoltz, Pradeep K. Singh, Edward F. McKone, Michael J. Welsh> ;JCI Insight. 2018 Aug 9
• 8 citations
  The vagal ganglia transcriptome identifies candidate therapeutics for airway hyperreactivity.
  Leah R. Reznikov, David K. Meyerholz, Mahmoud H. Abou Alaiwa, Shin-Ping Kuan, Yan-Shin J. Liao, Nicholas L. Bormann, Thomas B. Bair, Margaret P. Price, David A. Stoltz...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2018 Apr 5
• 29 citations
  Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs
  David K. Meyerholz, David A. Stoltz, Nicholas D. Gansemer, Sarah E. Ernst, Daniel P. Cook, Matthew D. Strub, Erica N. LeClair, Carrie K. Barker, Ryan J. Adam, Mariah R...> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 2018 Feb 21
• 122 citations
  Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis.
  Robert D. Gray, Gareth Hardisty, Kate H. Regan, Maeve P. Smith, Calum T. Robb, Rodger Duffin, Annie Mackellar, Jennifer M Felton, Lily Paemka, Brian N McCullagh, Chris...> ;Thorax. 2018 Feb 1
• 9 citations
  Cystic Fibrosis Transmembrane Conductance Regulator Potentiation as a Therapeutic Strategy for Pulmonary Edema: A Proof-of-Concept Study in Pigs.
  Xiaopeng Li, Luis G. Vargas Buonfiglio, Ryan J. Adam, David A. Stoltz, Joseph Zabner, Alejandro P. Comellas> ;Critical Care Medicine. 2017 Dec 1
• 7 citations
  CF airway smooth muscle transcriptome reveals a role for PYK2
  Daniel P. Cook, Ryan J. Adam, Keyan Zarei, Benjamin Deonovic, Mallory R. Stroik, Nicholas D. Gansemer, David K. Meyerholz, Kin Fai Au, David A. Stoltz> ;JCI Insight. 2017 Sep 7
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Journal Articles

• Ivacaftor-Induced Sweat Chloride Reductions Correlate with Increases in Airway Surface Liquid pH in Cystic Fibrosis  
  David A Stoltz, Joseph Zabner, The Journal of Clinical Investigation
• CFTR Gene Transfer with AAV Improves Early Cystic Fibrosis Pig Phenotypes  
  John R Weinstein, Joseph Zabner, David A Stoltz, The Journal of Clinical Investigation
• Lentiviral-Mediated Phenotypic Correction of Cystic Fibrosis Pigs  
  Drake C Bouzek, David A Stoltz, The Journal of Clinical Investigation