DavidEricSymerMDPhD

PubMed

• 1 citations
  Targeted single-cell proteomic analysis identifies new liquid biopsy biomarkers associated with multiple myeloma.
  Sonia M Setayesh, Libere J Ndacayisaba, Kate E Rappard, Valerie Hennes, Luz Yurany Moreno Rueda, Guilin Tang, Pei Lin, Robert Z Orlowski, David E Symer, Elisabet E Man...> ;NPJ Precision Oncology. 2023 Sep 18
• 6 citations
  Single cell clonotypic and transcriptional evolution of multiple myeloma precursor disease.
  Minghao Dang, Ruiping Wang, Hans C Lee, Krina K Patel, Melody R Becnel, Guangchun Han, Sheeba K Thomas, Dapeng Hao, Yanshuo Chu, Donna M Weber, Pei Lin, Zuzana Lutter-...> ;Cancer Cell. 2023 Jun 12
• 1 citations
  Noninvasive genomic profiling of somatic mutations in oral cavity cancers.
  Yuanxin Xi, Marcelo V Negrao, Keiko Akagi, Weihong Xiao, Bo Jiang, Sarah C Warner, Joe Dan Dunn, Jing Wang, David E Symer, Maura L Gillison> ;Oral Oncology. 2023 May 1
• 15 citations
  Intratumoral Heterogeneity and Clonal Evolution Induced by HPV Integration.
  Keiko Akagi, David E Symer, Medhat Mahmoud, Bo Jiang, Sara Goodwin, Darawalee Wangsa, Zhengke Li, Weihong Xiao, Joe Dan Dunn, Thomas Ried, Kevin R Coombes, Fritz J Sed...> ;Cancer Discovery. 2023 Apr 3
• 4 citations
  Enrichment-Free Single-Cell Detection and Morphogenomic Profiling of Myeloma Patient Samples to Delineate Circulating Rare Plasma Cell Clones.
  Libere J Ndacayisaba, Kate E Rappard, Stephanie N Shishido, Carmen Ruiz Velasco, Nicholas Matsumoto, Rafael Navarez, Guilin Tang, Pei Lin, Sonia M Setayesh, Amin Naghd...> ;Current Oncology. 2022 Apr 21
• 17 citations
  Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers.
  David E Symer, Keiko Akagi, Heather M Geiger, Yang Song, Gaiyun Li, Anne-Katrin Emde, Weihong Xiao, Bo Jiang, André Corvelo, Nora C Toussaint, Jingfeng Li, Amit Agrawa...> ;Genome Research. 2022 Jan 1
• 10 citations
  Human papillomavirus insertions identify the PIM family of serine/threonine kinases as targetable driver genes in head and neck squamous cell carcinoma
  Tatevik Broutian, Bo Jiang, Jingfeng Li, Keiko Akagi, Shanying Gui, Zhengqiu Zhou, Weihong Xiao, David E. Symer, Maura L. Gillison> ;Cancer Letters. 2020 Jan 17
• 36 citations
  Identification of Rare Variants Predisposing to Thyroid Cancer.
  Yanqiang Wang, Sandya Liyanarachchi, Katherine E. Miller, Taina T. Nieminen, Daniel F. Comiskey, W. G. Li, Pamela Brock, David E. Symer, Keiko Akagi, Katherine E. Dela...> ;Thyroid. 2019 Jul 17
• 144 citations
  Human papillomavirus and the landscape of secondary genetic alterations in oral cancers
  Maura L. Gillison, Keiko Akagi, Weihong Xiao, Bo Jiang, Robert K. L. Pickard, Jingfeng Li, Benjamin J. Swanson, Amit Agrawal, Mark Zucker, Birgit Stache-Crain, Anne-Ka...> ;Genome Research. 2019 Jan 1
• 8 citations
  Metaplastic breast cancer in a patient with neurofibromatosis type 1 and somatic loss of heterozygosity.
  Lorena P. Suarez-Kelly, Keiko Akagi, Julie W. Reeser, Eric Samorodnitsky, Matthew Reeder, Amy Smith, Sameek Roychowdhury, David E. Symer, William E. Carson> ;Cold Spring Harbor Molecular Case Studies. 2018 Apr 1
• 61 citations
  HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression
  Alix Warburton, Catherine J. Redmond, Katharine E. Dooley, Haiqing Fu, Maura L. Gillison, Keiko Akagi, David E. Symer, Mirit I. Aladjem, Alison A. McBride> ;Plos Genetics. 2018 Jan 24
• 96 citations
  In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice
  Mona El Refaey, Li Xu, Yandi Gao, Benjamin D. Canan, T.M. Ayodele Adesanya, Sarah Warner, Keiko Akagi, David E. Symer, Peter J. Mohler, Jianjie Ma, Paul M.L. Janssen, ...> ;Circulation Research. 2017 Aug 8
• 8 citations
  Dynamic silencing of somatic L1 retrotransposon insertions reflects the developmental and cellular contexts of their genomic integration.
  Manoj Kannan, Jingfeng Li, Sarah E. Fritz, Kathryn Elizabeth Husarek, Jonathan Christian Sanford, Teresa L. Sullivan, Pawan Kumar Tiwary, Wenfeng An, Jef D. Boeke, Dav...> ;Mobile DNA. 2017 May 10
• 36 citations
  HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes.
  Hang Yuan, Ewa Krawczyk, Jan Blancato, Christopher Albanese, Dan Zhou, Naidong Wang, Siddartha Paul, Faris Alkhilaiwi, Nancy Palechor-Ceron, Aleksandra Dakic, Shuang F...> ;Scientific Reports. 2017 Apr 5
• 77 citations
  Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma.
  Gabriel J. Starrett, Christina Marcelus, Paul G. Cantalupo, Joshua P. Katz, Jingwei Cheng, Keiko Akagi, Manisha Thakuria, Guilherme Rabinowits, Linda C. Wang, David E....> ;Mbio. 2017 Mar 8
• 73 citations
  A germline mutation in SRRM2, a splicing factor gene, is implicated in papillary thyroid carcinoma predisposition.
  Jerneja Tomsic, Huiling He, Keiko Akagi, Sandya Liyanarachchi, Qun Pan, Blake R. Bertani, Rebecca Nagy, David E. Symer, Benjamin J. Blencowe, Albert de la Chapelle> ;Scientific Reports. 2015 Jul 2
• 66 citations
  Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer
  Huiling He, W. G. Li, Sandya Liyanarachchi, Mukund Srinivas, Yanqiang Wang, Keiko Akagi, Yao Wang, Dayong Wu, Qianben Wang, Victor X. Jin, David E. Symer, Rulong Shen,...> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 May 12
• 101 citations
  The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection
  Christopher Schliehe, Elizabeth K Flynn, Bojan Vilagos, Udochuku Richson, Savitha Swaminathan, Berislav Bošnjak, Lisa Bauer, Richard Kumaran Kandasamy, Isabel M Griess...> ;Nature Immunology. 2015 Jan 1
• 32 citations
  An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition
  Jingfeng Li, Manoj Kannan, Anna L. Trivett, Hongling Liao, Xiaolin Wu, Keiko Akagi, David E. Symer> ;Nucleic Acids Research. 2014 Apr 1
• 314 citations
  Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
  Keiko Akagi, Jingfeng Li, Tatevik Broutian, Hesed Padilla-Nash, Weihong Xiao, Bo Jiang, James W. Rocco, Theodoros N. Teknos, Bhavna Kumar, Danny Wangsa, Dandan He, Tho...> ;Genome Research. 2014 Feb 1
• Collection and Preparation of Rodent Embryonic Samples for Transcriptome Study
  Yelena Golubeva, David E. Symer> ;Methods in Molecular Biology. 2014 Jan 1
• 46 citations
  Characterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to disease.
  Erin Hertlein, Kyle A. Beckwith, Gerard Lozanski, Timothy L. Chen, William H. Towns, Amy J. Johnson, Amy Lehman, Amy S. Ruppert, Brad Bolon, Leslie A. Andritsos, Arlet...> ;Plos One. 2013 Oct 9
• 32 citations
  Ultra-Rare Mutation in Long-Range Enhancer Predisposes to Thyroid Carcinoma with High Penetrance
  Huiling He, W. G. Li, Dayong Wu, Rebecca Nagy, Sandya Liyanarachchi, Keiko Akagi, Jarosław Jendrzejewski, Hong Jiao, Kevin W. Hoag, Bernard Wen, Mukund Srinivas, Gavis...> ;Plos One. 2013 May 14
• 67 citations
  SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility.
  Huiling He, Agnieszka Bronisz, Sandya Liyanarachchi, Rebecca Nagy, W. G. Li, Yungui Huang, Keiko Akagi, Motoyasu Saji, Dorota Kula, Anna Wojcicka, Nikhil Sebastian, Be...> ;The Journal of Clinical Endocrinology and Metabolism. 2013 Mar 28
• 15 citations
  How do mammalian transposons induce genetic variation? A conceptual framework: the age, structure, allele frequency, and genome context of transposable elements may de...
  Keiko Akagi, Jingfeng Li, David E. Symer> ;Bioessays. 2013 Jan 14
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