DavidHWagnerMD

PubMed

• Biomarker discovery in pre-Type 1 Diabetes; Th40 cells as a predictive risk factor.
  Vaitaitis, G. M.,Rihanek, M.,Alkanani, A. K.,Waid, D. M.,Gottlieb, P. A.,Wagner, D. H.> ;J. Clin. Endocrinol. Metab.. 2019 May 08
• Are we aiming to miss in translational autoimmunity treatments?
  Vaitaitis, G. M.,Wagner, D. H.> ;F1000Res. 2018 Dec 14
• A CD40-targeted peptide controls and reverses type 1 diabetes in NOD mice.
  Vaitaitis, G. M.,Olmstead, M. H.,Waid, D. M.,Carter, J. R.,Wagner, D. H.> ;Diabetologia. 2014 Aug 12
• An Alternative Role for Foxp3 As an Effector T Cell Regulator Controlled through CD40.
  Vaitaitis, G. M.,Carter, J. R.,Waid, D. M.,Olmstead, M. H.,Wagner, D. H.> ;J. Immunol.. 2013 Jul 15
• Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling.
  Chow, K.,Fessel, J. P.,Schmidt, E. P.,Gaskill, C.,Alvarez, D.,Graham, B.,Harrison, D. G.,Wagner, D. H.,Nozik-Grayck, E.,West, J. D.,Klemm, D. J.,Majka, S. M.> ;Pulm Circ. 2013 Jan
• CD40 engagement of CD4(+) CD40(+) T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance.
  Carter, J., Vaitaitis, G.M., Waid, D.M., Wagner, D.H.> ;Eur J Immunol. 2012 Feb
• The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation.
  Jun, D., Garat, C., West, J., Thorn, N., Chow, K., Cleaver, T., Sullivan, T., Torchia, E.C., Childs, C., Shade, T., Tadjali, M., Lara, A., Nozik-Grayck, E., Malkoski, ...> ;Stem Cells. 2011 Apr
• Isolation & Characterization of Hoechst^low CD45^negative Mouse Lung Mesenchymal Stem Cells.
  Chow, K.S., Jun, D., Helm, K.M., Wagner, D.H., Majka, S.M.> ;J Vis Exp. 2011
• Disruption of the homeostatic balance between autoaggressive (CD4+CD40+) and regulatory (CD4+CD25+FoxP3+) T cells promotes diabetes.
  Waid, D.M., Vaitaitis, G.M., Pennock, N.D., Wagner, D.H.> ;J Leukoc Biol. 2008 Aug
• An analytical workflow for investigating cytokine profiles.
  Siebert, J.C., Inokuma, M., Waid, D.M., Pennock, N.D., Vaitaitis, G.M., Disis, M.L., Dunne, J.F., Wagner, D.H., Maecker, H.T.> ;Cytometry A. 2008 Apr
• High distribution of CD40 and TRAF2 in Th40 T cell rafts leads to preferential survival of this auto-aggressive population in autoimmunity.
  Vaitaitis, G.M., Wagner, D.H.> ;PLoS One. 2008
• A unique T cell subset described as CD4loCD40+ T cells (TCD40) in human type 1 diabetes.
  Waid, D.M., Wagner, R.J., Putnam, A., Vaitaitis, G.M., Pennock, N.D., Calverley, D.C., Gottlieb, P., Wagner, D.H.> ;Clin Immunol. 2007 Aug
• Re-shaping the T cell repertoire: TCR editing and TCR revision for good and for bad.
  Wagner, D.H.> ;Clin Immunol. 2007 Apr
• Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: a mechanism for the generation of autoaggressive T cells in the periphery.
  Vaitaitis, G.M., Poulin, M., Sanderson, R.J., Haskins, K., Wagner, D.H.> ;J Immunol. 2003 Apr 1
• Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes.
  Wagner, D.H., Vaitaitis, G., Sanderson, R., Poulin, M., Dobbs, C., Haskins, K.> ;Proc Natl Acad Sci U S A. 2002 Mar 19
• gamma delta+ T cells regulate major histocompatibility complex class II(IA and IE)-dependent susceptibility to coxsackievirus B3-induced autoimmune myocarditis.
  Huber, S. A., Stone, J. E., Wagner, D. H., Kupperman, J., Pfeiffer, L., David, C., O'Brien, R. L., Davis, G. S., Newell, M. K.> ;J Virol. 1999 Jul
• IL-4 and IL-10 modulation of CD40-mediated signaling of monocyte IL-1beta synthesis and rescue from apoptosis.
  Poe, J. C., Wagner, D. H., Miller, R. W., Stout, R. D., Suttles, J.> ;J Immunol. 1997 Jul 15
• The co-evolution of our understanding of CD40 and inflammation.
  Wagner, D. H.> ;Diabetologia. 2009 Jun 01
• Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2.
  Wagner, D. H., Hagman, J., Linsley, P. S., Hodsdon, W., Freed, J. H., Newell, M. K.> ;J Exp Med. 1996 Nov 1
• Role of the CD40-CD40 ligand interaction in CD4+ T cell contact-dependent activation of monocyte interleukin-1 synthesis.
  Wagner, D. H., Stout, R. D., Suttles, J.> ;Eur J Immunol. 1994 Dec
• Increased expression of CD40 on thymocytes and peripheral T cells in autoimmunity: a mechanism for acquiring changes in the peripheral T cell receptor repertoire.
  Wagner, D. H., Newell, E., Sanderson, R. J., Freed, J. H., Newell, M. K.> ;Int J Mol Med. 1999 Sep
• CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunity.
  Vaitaitis, G. M., Wagner, D. H.> ;Mol Immunol. 2010 Aug
• Peripheral CD4loCD40+ auto-aggressive T cell expansion during insulin-dependent diabetes mellitus.
  Waid, D. M., Vaitaitis, G. M., Wagner, D. H.> ;Eur J Immunol. 2004 May
• CD40 on NOD CD4 T cells contributes to their activation and pathogenicity.
  Baker, R. L., Wagner, D. H., Haskins, K.> ;J Autoimmun. 2008 Dec 01
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