DavidNWaldMD

PubMed

• Flow cytometry of DNMT1 as a biomarker of hypomethylating therapies.
  Philip G Woost, Basem M William, Brenda W Cooper, Masumi Ueda Oshima, Folashade Otegbeye, Marcos J De Lima, David Wald, Reda Z Mahfouz, Yogen Saunthararajah, Tammy Ste...> ;Cytometry. Part B, Clinical Cytometry. 2024 Jan 1
• Chimeric Antigen Receptor (CAR)-T Cell Therapy for Non-Hodgkin's Lymphoma.
  Maria Florencia Giraudo, Zachary Jackson, Indrani Das, Olubukola M Abiona, David N Wald> ;Pathogens & Immunity. 2024 Jan 1
• Loss of GSK3β in hematopoietic stem cells results in normal hematopoiesis in mice.
  Grace Lee, Jude Franklin, Kalpana Gupta, Ruifu Liu, Lan Zhou, Christopher Ryder, Lukasz Sobieraj, Luke Molitor, Olubukola Abiona, Howard Meyerson, Indrani Das, Zachary...> ;Blood Advances. 2023 Dec 12
• 2 citations
  NK cells from COVID-19 positive patients exhibit enhanced cytotoxic activity upon NKG2A and KIR2DL1 blockade.
  Grace Lee, Robert Schauner, Juanita Burke, Jade Borocz, Smitha Vasana, Lukasz Sobieraj, Maria Giraudo, Zachary Jackson, Qasim Ansari, Maria Navas, Hany Sakr, David Wald> ;Frontiers in Immunology. 2023 Jan 1
• 13 citations
  An effective and chemotherapy-free strategy of all-trans retinoic acid and arsenic trioxide for acute promyelocytic leukemia in all risk groups (APL15 trial).
  Huai-Yu Wang, Sha Gong, Guo-Hui Li, Ya-Zhou Yao, Yin-Suo Zheng, Xiao-Hong Lu, Su-Hua Wei, Wei-Wei Qin, Hai-Bo Liu, Meng-Chang Wang, Jie-Ying Xi, Li-Mei Chen, Mei Zhang...> ;Blood Cancer Journal. 2022 Nov 21
• During HCV DAA Therapy Plasma Mip1B, IP10, and miRNA Profile Are Distinctly Associated with Subsequent Diagnosis of Hepatocellular Carcinoma: A Pilot Study.
  Sofi Damjanovska, Hawwa Alao, Elizabeth Zebrowski, Corinne Kowal, Lenche Kostadinova, Perica Davitkov, Yngve Falck-Ytter, Carey L Shive, Michael Cartwright, Brian Rich...> ;Biology. 2022 Aug 25
• 7 citations
  Sequential Single-Cell Transcriptional and Protein Marker Profiling Reveals TIGIT as a Marker of CD19 CAR-T Cell Dysfunction in Patients with Non-Hodgkin Lymphoma.
  Zachary Jackson, Changjin Hong, Robert Schauner, Boro Dropulic, Paolo F Caimi, Marcos de Lima, Maria Florencia Giraudo, Kalpana Gupta, Jane S Reese, Tae Hyun Hwang, Da...> ;Cancer Discovery. 2022 Aug 5
• 2 citations
  Re-Expression of ERα and AR in Receptor Negative Endocrine CancersGSK3 Inhibition.
  Vikas Sharma, Jayadev Joshi, I-Ju Yeh, YongQiu Doughman, Daniel Blankenberg, David Wald, Monica M Montano> ;Frontiers in Oncology. 2022 Jan 1
• 3 citations
  Chemical screening identifies novel small molecule activators of natural killer cell cytotoxicity against cancer cells
  Grace Lee, Sheela Karunanithi, Bruce A. Posner, Hanspeter Niederstrasser, Hong Cheng, Yuriy Federov, Shivaprasad Manjappa, Karam Musaitif, Huaiyu Wang, Zachary Jackson...> ;Cancer Immunology, Immunotherapy. 2021 Nov 23
• 34 citations
  Single cell RNA sequencing of AML initiating cells reveals RNA-based evolution during disease progression.
  Lindsay Stetson, Dheepa Balasubramanian, Susan Pereira Ribeiro, Tammy Stefan, Kalpana Gupta, Xuan Xu, Slim Fourati, Anne Roe, Zachary Jackson, Robert Schauner, Ashish ...> ;Leukemia. 2021 Jul 9
• 9 citations
  Thioredoxin reductase is a major regulator of metabolism in leukemia cells.
  Sheelarani Karunanithi, Ruifu Liu, Yongchun Hou, Giancarlo Gonzalez, Natasha Oldford, Anne Roe, Nethrie Idipilly, Kalpana Gupta, Chandra Sekhar Amara, Satwikreddy Putl...> ;Oncogene. 2021 Jul 8
• 51 citations
  Automated Manufacture of Autologous CD19 CAR-T Cells for Treatment of Non-hodgkin Lymphoma
  Zachary Jackson, Anne Roe, Ashish Sharma, Filipa Blasco Tavares Pereira Lopes, Aarthi Talla, Sarah Kleinsorge-Block, Kayla Zamborsky, Jennifer Schiavone, Shivaprasad M...> ;Frontiers in Immunology. 2020 Aug 7
• 4 citations
  Analysis of epigenetic aging in vivo and in vitro: Factors controlling the speed and direction.
  Mieko Matsuyama, Arne Søraas, Sarah Yu, Kyuhyeon Kim, Evi X. Stavrou, Paolo Caimi, David N. Wald, Marcos deLima, John Arne Dahl, Steve Horvath, Shigemi Matsuyama> ;Experimental Biology and Medicine. 2020 Aug 6
• 14 citations
  Affinity of plant viral nanoparticle potato virus X (PVX) towards malignant B cells enables cancer drug delivery
  Sourabh Shukla, Anne Roe, Ruifu Liu, Frank A. Veliz, Ulrich Commandeur, David N. Wald, Nicole F. Steinmetz> ;Biomaterials Science. 2020 Jul 14
• 8 citations
  Phase I Trial of Lithium and Tretinoin for Treatment of Relapsed and Refractory Non-promyelocytic Acute Myeloid Leukemia.
  Masumi Ueda, Tammy Stefan, Lindsay Stetson, James J. Ignatz-Hoover, Benjamin Tomlinson, Richard J. Creger, Brenda W. Cooper, Hillard M. Lazarus, Marcos de Lima, David ...> ;Frontiers in Oncology. 2020 Mar 10
• 57 citations
  Membrane bound IL-21 based NK cell feeder cells drive robust expansion and metabolic activation of NK cells.
  Evelyn Ojo, Ashish Sharma, Ruifu Liu, Stephen Moreton, Mary Ann Checkley-Luttge, Kalpana Gupta, Grace Lee, Dean A. Lee, Folashade Otegbeye, Rafick Pierre Sekaly, Marco...> ;Scientific Reports. 2019 Oct 17
• 8 citations
  Low-Dose Azacitidine with DNMT1 Level Monitoring to Treat Post-Transplantation Acute Myelogenous Leukemia or Myelodysplastic Syndrome Relapse
  Masumi Ueda, Najla El-Jurdi, Brenda W. Cooper, Paolo Caimi, Linda Baer, Merle Kolk, Lauren Brister, David N. Wald, Folashade Otegbeye, Hillard M. Lazarus, Brenda M. Sa...> ;Biology of Blood and Marrow Transplantation. 2019 Jun 1
• 3 citations
  Lipocalin 24p3 Induction in Colitis Adversely Affects Inflammation and Contributes to Mortality
  Zhuoming Liu, Fabio Cominelli, Luca Di Martino, Ruifu Liu, Neha Devireddy, Lax R Devireddy, David N. Wald> ;Frontiers in Immunology. 2019 Apr 17
• 34 citations
  Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells.
  Arne Søraas, Mieko Matsuyama, Marcos de Lima, David N. Wald, Jochen Buechner, Tobias Gedde-Dahl, Camilla Lund Søraas, Brian H. Chen, Luigi Ferrucci, John Arne Dahl, St...> ;Aging Cell. 2019 Feb 2
• 12 citations
  Mismatch repair-signature mutations activate gene enhancers across human colorectal cancer epigenomes.
  Stevephen Hung, Alina Saiakhova, Zachary J Faber, Cynthia F. Bartels, Devin Neu, Ian Bayles, Evelyn Ojo, Ellen S. Hong, W Dean Pontius, Andrew R. Morton, Ruifu Liu, Ma...> ;Elife. 2019 Feb 13
• 24 citations
  Aberrant GSK3β nuclear localization promotes AML growth and drug resistance
  James J. Ignatz-Hoover, Victoria Wang, Nathan Mackowski, Anne Roe, Isaac K. Ghansah, Masumi Ueda, Hillard M. Lazarus, Marcos de Lima, Elisabeth Paietta, Hugo F. Fernan...> ;Blood Advances. 2018 Nov 13
• 85 citations
  Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates
  Xiaorong Gu, Quteba Ebrahem, Reda Z. Mahfouz, Metis Hasipek, Francis Enane, Tomas Radivoyevitch, Nicolas Rapin, Bartlomiej P Przychodzen, Zhenbo Hu, Ramesh Balusu, Cla...> ;The Journal of Clinical Investigation. 2018 Oct 1
• Development and validation of an LC-MS/MS method for quantitative determination of GS87, a novel antineoplastic agent, in mouse plasma.
  Sandeep R. Kunati, Shuming Yang, David N. Wald, Yan Xu> ;Journal of Pharmaceutical and Biomedical Analysis. 2018 May 10
• 15 citations
  A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor support
  Amar Desai, Yongyou Zhang, Young Soo Park, Dawn M. Dawson, Gretchen A. LaRusch, Lakshmi Kasturi, David N. Wald, Joseph M. Ready, Stanton L. Gerson, Sanford D. Markowitz> ;Haematologica. 2018 Jun 1
• Inhibiting TGF-beta signaling preserves the function of highly activated, in vitro expanded natural killer cells in AML and colon cancer models.
  Otegbeye, F.,Ojo, E.,Moreton, S.,Mackowski, N.,Lee, D. A.,de Lima, M.,Wald, D. N.> ;PLoS ONE. 2018 Jan 18
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Abstracts/Posters

• Small Molecule Screening Identifies Rho-Associate Protein Kinase (ROCK) As a Regulator of NK Cell Cytotoxicity Against Cancer
  David Wald, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Phase 1 Study of on Site Manufactured Anti-CD19 CAR-T Cells: Responses in Subjects with Rapidly Progressive Refractory Lymphomas
  David Wald, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019