DavidKWilsonMD

PubMed

• Structure and specificity of several triclocarban-binding single domain camelid antibody fragments.
  Tabares-da Rosa, S.,Wogulis, L. A.,Wogulis, M. D.,González-Sapienza, G.,Wilson, D. K.> ;J. Mol. Recognit.. 2018 Jul 24
• Speeding up the product release: a second-sphere contribution from Tyr191 to the reactivity of l-lactate oxidase revealed in crystallographic and kinetic studies of si...
  Stoisser, T.,Klimacek, M.,Wilson, D. K.,Nidetzky, B.> ;FEBS J.. 2015 Aug 12
• Crystallographic Observation of pH-Induced Conformational Changes in the Amyelois transitella Pheromone-Binding Protein AtraPBP1.
  di Luccio, E.,Ishida, Y.,Leal, W. S.,Wilson, D. K.> ;PLoS ONE. 2013
• Function of phenylalanine 259 and threonine 314 within the substrate binding pocket of the juvenile hormone esterase of Manduca sexta.
  Kamita, S.G., Wogulis, M.D., Law, C.S., Morisseau, C., Tanaka, H., Huang, H., Wilson, D.K., Hammock, B.D.> ;Biochemistry. 2010 May 4
• Comprehensive X-ray structural studies of the quinolinate phosphoribosyl transferase (BNA6) from Saccharomyces cerevisiae.
  di Luccio, E., Wilson, D.K.> ;Biochemistry. 2008 Apr 1
• Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evi...
  Wogulis, M., Chew, E.R., Donohoue, P.D., Wilson, D.K.> ;Biochemistry. 2008 Feb 12
• 7 citations
  On-bead combinatorial techniques for the identification of selective aldose reductase inhibitors.
  Lori I. Robins, Seth Dixon, David K. Wilson, Mark J. Kurth> ;Bioorganic & Medicinal Chemistry. 2006 Dec 1
• Structural studies of a potent insect maturation inhibitor bound to the juvenile hormone esterase of Manduca sexta.
  Wogulis, M., Wheelock, C.E., Kamita, S.G., Hinton, A.C., Whetstone, P.A., Hammock, B.D., Wilson, D.K.> ;Biochemistry. 2006 Apr 4
• Structure-guided engineering of xylitol dehydrogenase cosubstrate specificity.
  Ehrensberger, A.H., Elling, R.A., Wilson, D.K.> ;Structure. 2006 Mar
• The crystal structure of an odorant binding protein from Anopheles gambiae: evidence for a common ligand release mechanism.
  Wogulis, M., Morgan, T., Ishida, Y., Leal, W.S., Wilson, D.K.> ;Biochem Biophys Res Commun. 2006 Jan 6
• The 1.1-angstrom structure of the spindle checkpoint protein Bub3p reveals functional regions.
  Wilson, D.K., Cerna, D., Chew, E.> ;J Biol Chem. 2005 Apr 8
• The structure of Ski8p, a protein regulating mRNA degradation: Implications for WD protein structure.
  Madrona, A.Y., Wilson, D.K.> ;Protein Sci. 2004 Jun
• Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant.
  Kratzer, R., Kavanagh, K.L., Wilson, D.K., Nidetzky, B.> ;Biochemistry. 2004 May 4
• Structure of Toxoplasma gondii LDH1: active-site differences from human lactate dehydrogenases and the structural basis for efficient APAD+ use.
  Kavanagh, K.L., Elling, R.A., Wilson, D.K.> ;Biochemistry. 2004 Feb 3
• The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization.
  Voegtli, W.C., Madrona, A.Y., Wilson, D.K.> ;J Biol Chem. 2003 Sep 5
• Crystal structure of Pseudomonas fluorescens mannitol 2-dehydrogenase binary and ternary complexes. Specificity and catalytic mechanism.
  Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.> ;J Biol Chem. 2002 Nov 8
• The structure of apo and holo forms of xylose reductase, a dimeric aldo-keto reductase from Candida tenuis.
  Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.> ;Biochemistry. 2002 Jul 16
• Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: substitution of histidine 238 does not impede hydroxylate formation.
  Sideraki V, Wilson DK, Kurz LC, Quiocho FA, Rudolph FB> ;Biochemistry. 1996-11-26
• 351 citations
  An unlikely sugar substrate site in the 1.65 Å structure of the human aldose reductase holoenzyme implicated in diabetic complications
  David K. Wilson, Kurt M. Bohren, Kenneth H. Gabbay, Florante A. Quiocho> ;Science. 1992 Jul 3
• 315 citations
  Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations
  David K. Wilson, Frederick B. Rudolph, Florante A. Quiocho> ;Science. 1991 May 31
• Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases.
  Kavanagh, K. L., Klimacek, M., Nidetzky, B., Wilson, D. K.> ;Biochem J. 2003 Jul 15
• Pseudomonas fluorescens mannitol 2-dehydrogenase and the family of polyol-specific long-chain dehydrogenases/reductases: sequence-based classification and analysis of ...
  Klimacek, M., Kavanagh, K. L., Wilson, D. K., Nidetzky, B.> ;Chem Biol Interact. 2003 Feb 1
• Crystal structure of Pseudomonas fluorescens mannitol 2-dehydrogenase: evidence for a very divergent long-chain dehydrogenase family.
  Kavanagh, K. L., Klimacek, M., Nidetzky, B., Wilson, D. K.> ;Chem Biol Interact. 2003 Feb 1
• Altering dimer contacts in xylose reductase from Candida tenuis by site-directed mutagenesis: structural and functional properties of R180A mutant.
  Klimacek, M., Wührer, F., Kavanagh, K. L., Wilson, D. K., Nidetzky, B.> ;Chem Biol Interact. 2003 Feb 1
• The xylose reductase (AKR2B5) structure: homology and divergence from other aldo-keto reductases and opportunities for protein engineering.
  Wilson, D. K., Kavanagh, K. L., Klimacek, M., Nidetzky, B.> ;Chem Biol Interact. 2003 Feb 1
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