DavidPaulWitteMD

PubMed

• 4 citations
  Excessive IL-10 and IL-18 trigger hemophagocytic lymphohistiocytosis-like hyperinflammation and enhanced myelopoiesis.
  Yuting Tang, Qian Xu, Hui Luo, Xiaomei Yan, Gaoxiang Wang, Liang Hu, Jin Jin, David P Witte, Rebecca A Marsh, Liang Huang, Gang Huang, Jianfeng Zhou> ;The Journal of Allergy and Clinical Immunology. 2022 Nov 1
• 7 citations
  Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin.
  Sonya Ruiz-Torres, Marion G. Brusadelli, David P. Witte, Kathryn A. Wikenheiser-Brokamp, Sharon Sauter, Adam S. Nelson, Mathieu Sertorio, Timothy M. Chlon, Adam Lane, ...> ;Cell Stem Cell. 2021 Mar 4
• 25 citations
  A phase I/II study of ribociclib following radiation therapy in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG).
  Mariko DeWire, Christine Fuller, Trent R. Hummel, Lionel M L Chow, Ralph Salloum, Peter de Blank, Luke Pater, Sarah A. Lawson, Xiaoting Zhu, Phil Dexheimer, Adam C. Ca...> ;Journal of Neuro-Oncology. 2020 Oct 9
• 11 citations
  Highly Sensitive Blocker Displacement Amplification and Droplet Digital PCR Reveal Low-Level Parental FOXF1 Somatic Mosaicism in Families with Alveolar Capillary Dyspl...
  Justyna A. Karolak, Qian Liu, Nina G. Xie, Lucia R. Wu, Gustavo Rocha, Susana Fernandes, Luk Ho-ming, Ivan F M Lo, David Mowat, Elizabeth K. Fiorino, Morris Edelman, J...> ;The Journal of Molecular Diagnostics. 2020 Apr 1
• 7 citations
  A novel pathogenic variant in OFD1 results in X-linked Joubert syndrome with orofaciodigital features and pituitary aplasia
  Deema Aljeaid, Rachel C. Lombardo, David P. Witte, Robert J. Hopkin> ;American Journal of Medical Genetics. Part A. 2019 Jun 1
• 17 citations
  Combination of acid β-glucosidase mutation and Saposin C deficiency in mice reveals Gba1 mutation dependent and tissue-specific disease phenotype
  Benjamin Liou, Wujuan Zhang, Venette Fannin, Brian Quinn, Huimin Ran, Kui Xu, Kenneth D.R. Setchell, David P. Witte, Gregory A. Grabowski, Ying Sun> ;Scientific Reports. 2019 Apr 3
• 19 citations
  Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity.
  Jessica L Turnier, Hermine I. Brunner, Michael J. Bennett, Ashwaq AlE'ed, Gaurav Gulati, Wendy D. Haffey, Sherry Thornton, Michael Wagner, Prasad Devarajan, David P. W...> ;Rheumatology. 2019 Feb 1
• 24 citations
  Urine biomarkers of chronic kidney damage and renal functional decline in childhood-onset systemic lupus erythematosus
  Hermine I. Brunner, Gaurav Gulati, Marisa S. Klein-Gitelman, Kelly Rouster-Stevens, Lori B. Tucker, Stacey P. Ardoin, Karen Onel, Jessica L Turnier, Pinar Ozge Avar Ay...> ;Pediatric Nephrology. 2019 Jan 1
• 7 citations
  Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma.
  Tuna Toptan, Marion G. Brusadelli, Brian Turpin, David P. Witte, Jordi Surrallés, Eunike Velleuer, Martin Schramm, Ralf Dietrich, Ruud H. Brakenhoff, Patrick S. Moore,...> ;Plos One. 2018 Dec 27
• 32 citations
  Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes
  Yoshihiro Hayashi, Yue Zhang, Asumi Yokota, Xiaomei Yan, Jinqin Liu, Kwangmin Choi, Bing Li, Goro Sashida, Yanyan Peng, Zefeng Xu, Rui Huang, Lulu Zhang, George M. Fre...> ;Cancer Discovery. 2018 Nov 1
• 25 citations
  Protease-activated receptor-1 impedes prostate and intestinal tumor progression in mice.
  Gregory N. Adams, Bal Krishan Sharma, Leah Rosenfeldt, Malinda Frederick, Matthew J. Flick, David P. Witte, Laurent O. Mosnier, Eleana Harmel-Laws, Kris A. Steinbreche...> ;Journal of Thrombosis and Haemostasis. 2018 Nov 1
• 25 citations
  Hamartin regulates cessation of mouse nephrogenesis independently of Mtor.
  Oded Volovelsky, Thi Nguyen, Alison E. Jarmas, Alexander N. Combes, Sean B. Wilson, Melissa H. Little, David P. Witte, Eric W. Brunskill, Raphael Kopan> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 May 21
• 22 citations
  Correction of GSK3β at young age prevents muscle pathology in mice with myotonic dystrophy type 1.
  Christina Wei, Lauren Stock, Leila Valanejad, Zachary A. Zalewski, Rebekah Karns, Jack Puymirat, David L. Nelson, David P. Witte, James R. Woodgett, Nikolai A. Timchen...> ;FASEB Journal. 2017 Dec 4
• 45 citations
  Urine S100 proteins as potential biomarkers of lupus nephritis activity
  Jessica L Turnier, Ndate Fall, Sherry Thornton, David P. Witte, Michael R. Bennett, Simone Appenzeller, Marisa S. Klein-Gitelman, Alexei A. Grom, Hermine I. Brunner> ;Arthritis Research & Therapy. 2017 Oct 24
• 31 citations
  FXR-Gankyrin axis is involved in development of pediatric liver cancer.
  Leila Valanejad, Kyle Lewis, Mary Wright, Yanjun Jiang, Amber M. D'Souza, Rebekah Karns, Rachel Sheridan, Anita Gupta, Kevin E. Bove, David P. Witte, James I. Geller, ...> ;Carcinogenesis. 2017 Jul 1
• 34 citations
  Urine Biomarkers to Predict Response to Lupus Nephritis Therapy in Children and Young Adults
  Hermine I. Brunner, Michael R. Bennett, Gaurav Gulati, Khalid Abulaban, Marisa S. Klein-Gitelman, Stacy P. Ardoin, Lori B. Tucker, Kelly Rouster-Stevens, David Witte, ...> ;The Journal of Rheumatology. 2017 Jun 15
• 21 citations
  Inter-observer variability of the histological classification of lupus glomerulonephritis in children
  Louise Oni, Michael W. Beresford, David P. Witte, A Chatzitolios, Neil J. Sebire, Khalid Abulaban, R Shukla, Jun Ying, Hermine I. Brunner> ;Lupus. 2017 May 7
• 131 citations
  Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease
  Manoj K. Pandey, Thomas A. Burrow, Reena Rani, Lisa J. Martin, David P. Witte, Kenneth D.R. Setchell, Mary McKay, Albert F. Magnusen, Wujuan Zhang, Benjamin Liou, Jörg...> ;Nature. 2017 Mar 2
• 15 citations
  Successful Simultaneous Liver-Kidney Transplantation in the Presence of Multiple High-Titered Class I and II Antidonor HLA Antibodies.
  Flavio Paterno, Alin Girnita, Paul Brailey, David P. Witte, Jiang Wang, Madison C. Cuffy, Tayyab S. Diwan, Simon Tremblay, Jane Y. Revollo, Rita R. Alloway, Michael R....> ;Transplantation Direct. 2016 Nov 23
• 5 citations
  The Noninvasive Urinary Polyomavirus Haufen Test Predicts BK Virus Nephropathy in Children After Hematopoietic Cell Transplantation: A Pilot Study.
  Benjamin L. Laskin, Harsharan K. Singh, Ulf H. Beier, Taylor Moatz, Susan L. Furth, Nancy Bunin, David P. Witte, Jens Goebel, Stella M. Davies, Christopher E. Dandoy, ...> ;Transplantation. 2016 Oct 1
• 9 citations
  Deep Sequencing Reveals Novel Genetic Variants in Children with Acute Liver Failure and Tissue Evidence of Impaired Energy Metabolism.
  C. Alexander Valencia, Xinjian Wang, Jin Wang, Anna L. Peters, Julia Simmons, Molly C. Moran, Abhinav Mathur, Ammar Husami, Yaping Qian, Rachel Sheridan, Kevin E. Bove...> ;Plos One. 2016 Aug 2
• 44 citations
  Development of a Novel Renal Activity Index of Lupus Nephritis in Children and Young Adults.
  Hermine I. Brunner, Michael R. Bennett, Khalid Abulaban, Marisa S. Klein-Gitelman, Kathleen M. O’Neil, Lori B. Tucker, Stacy P. Ardoin, Kelly Rouster-Stevens, Karen On...> ;Arthritis Care & Research. 2016 Jul 1
• 24 citations
  Neonatal multiorgan failure due to ACAD9 mutation and complex I deficiency with mitochondrial hyperplasia in liver, cardiac myocytes, skeletal muscle, and renal tubules.
  Nancy D. Leslie, Xinjian Wang, Yanyan Peng, C. Alexander Valencia, Zaza Khuchua, Jessica Hata, David P. Witte, Taosheng Huang, Kevin E. Bove> ;Human Pathology. 2016 Mar 1
• 123 citations
  Chd7 Cooperates with Sox10 and Regulates the Onset of CNS Myelination and Remyelination
  Danyang He, Corentine Marie, Chuntao Zhao, Bong-Woo Kim, Jincheng Wang, Yaqi Deng, Adrien Clavairoly, Magali Frah, Haibo Wang, Xuelian He, Hatem Hmidan, Blaise V. Jone...> ;Nature Neuroscience. 2016 May 1
• 24 citations
  Validation of the Lupus Nephritis Clinical Indices in Childhood-Onset Systemic Lupus Erythematosus.
  Rina Mina, Khalid Abulaban, Marisa S. Klein-Gitelman, Barbara A. Eberhard, Stacy P. Ardoin, Nora G. Singer, Karen Onel, Lori B. Tucker, Kathleen M. O'Neil, Tracey Wrig...> ;Arthritis Care & Research. 2016 Feb 1
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Journal Articles

• Discovery of SERPINA3 as a Candidate Urinary Biomarker of Lupus Nephritis Activity  
  Michael Bennett, Hermine I Brunner, Prasad Devarajan, Gaurav Gulati, Jessica L Turnier, Sherry Thornton, David Witte, Bruce Aronow, Rheumatology