DavidYuMD

PubMed

• Radiation and anti-PD-L1 synergize by stimulating a stem-like T cell population in the tumor-draining lymph node.
  Yang Shen, Erin Connolly, Meili Aiello, Chengjing Zhou, Prasanthi Chappa, Haorui Song, Patan Tippitak, Tarralyn Clark, Maria Cardenas, Nataliya Prokhnevska, Annapaola ...> ;Research Square. 2024 Mar 6
• ATR signaling controls the bystander responses of human chondrosarcoma cells by promoting RAD51-dependent DNA repair.
  Nho Cong Luong, Hidemasa Kawamura, Hiroko Ikeda, Reiko T Roppongi, Atsushi Shibata, Jiaxuan Hu, Jinmeng G Jiang, David S Yu, Kathryn D Held> ;International Journal of Radiation Biology. 2024 Mar 5
• SAMHD1 expression contributes to doxorubicin resistance and predicts survival outcomes in diffuse large B-cell lymphoma patients.
  Daddacha, W., Monroe, D., Schlafstein, A., Withers, A., Thompson, E., Danelia, D., Luong, N., Sesay, F., Rath, S., Usoro, E., Essien, M., Jung, A., Jiang, J., Hu, J., ...> ;NAR Cancer. 2024 Mar 1
• A retrospective study on the investigation of potential dosimetric benefits of online adaptive proton therapy for head and neck cancer.
  Chang, C., Bohannon, D., Tian, Z., Wang, Y., Liu, T., Zhou, J., Yang, X., Mcdonald, M., Yu, D.> ;Journal of Applied Clinical Medical Physics. 2024 Feb 18
• The putative RNA helicase DDX1 associates with the nuclear RNA exosome and modulates RNA/DNA hybrids (R-loops).
  Julia L de Amorim, Sara W Leung, Ramona Haji-Seyed-Javadi, Yingzi Hou, David S Yu, Homa Ghalei, Sohail Khoshnevis, Bing Yao, Anita H Corbett> ;The Journal of Biological Chemistry. 2024 Feb 1
• Streamlined pin-ridge-filter design for single-energy proton FLASH planning.
  Chaoqiong Ma, Jun Zhou, Chih-Wei Chang, Yinan Wang, Pretesh R Patel, David S Yu, Sibo Tian, Xiaofeng Yang> ;Medical Physics. 2024 Apr 1
• 2 citations
  Synthetic CT generation from MRI using 3D transformer-based denoising diffusion model.
  Shaoyan Pan, Elham Abouei, Jacob Wynne, Chih-Wei Chang, Tonghe Wang, Richard L J Qiu, Yuheng Li, Junbo Peng, Justin Roper, Pretesh Patel, David S Yu, Hui Mao, Xiaofeng...> ;Medical Physics. 2024 Apr 1
• 8 citations
  CBCT-Based synthetic CT image generation using conditional denoising diffusion probabilistic model.
  Junbo Peng, Richard L J Qiu, Jacob F Wynne, Chih-Wei Chang, Shaoyan Pan, Tonghe Wang, Justin Roper, Tian Liu, Pretesh R Patel, David S Yu, Xiaofeng Yang> ;Medical Physics. 2024 Mar 1
• 2 citations
  DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining.
  PamelaSara E Head, Priya Kapoor-Vazirani, Ganji P Nagaraju, Hui Zhang, Sandip K Rath, Nho C Luong, Ramona Haji-Seyed-Javadi, Fatmata Sesay, Shi-Ya Wang, Duc M Duong, W...> ;Nucleic Acids Research. 2023 Aug 25
• Author Correction: YB1 modulates the DNA damage response in medulloblastoma.
  Leon F McSwain, Claire E Pillsbury, Ramona Haji-Seyed-Javadi, Sandip Kumar Rath, Victor Chen, Tiffany Huang, Shubin W Shahab, Haritha Kunhiraman, James Ross, Gabrielle...> ;Scientific Reports. 2023 Jun 15
• 2 citations
  YB1 modulates the DNA damage response in medulloblastoma.
  Leon F McSwain, Claire E Pillsbury, Ramona Haji-Seyed-Javadi, Sandip Kumar Rath, Victor Chen, Tiffany Huang, Shubin W Shahab, Haritha Kunhiraman, James Ross, Gabrielle...> ;Scientific Reports. 2023 May 19
• 8 citations
  SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks.
  Priya Kapoor-Vazirani, Sandip K Rath, Xu Liu, Zhen Shu, Nicole E Bowen, Yitong Chen, Ramona Haji-Seyed-Javadi, Waaqo Daddacha, Elizabeth V Minten, Diana Danelia, Danie...> ;Nature Communications. 2022 Nov 7
• 3 citations
  Deformable CT image registration via a dual feasible neural network.
  Yang Lei, Yabo Fu, Zhen Tian, Tonghe Wang, Xianjin Dai, Justin Roper, David S Yu, Mark McDonald, Jeffrey D Bradley, Tian Liu, Jun Zhou, Xiaofeng Yang> ;Medical Physics. 2022 Dec 1
• 4 citations
  Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates.
  Hui Zhang, Eric B Dammer, Duc M Duong, Diana Danelia, Nicholas T Seyfried, David S Yu> ;Scientific Reports. 2022 Mar 9
• 5 citations
  Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
  Nicole E. Bowen, Joshua Temple, Caitlin Shepard, Adrian Oo, Fidel Arizaga, Priya Kapoor-Vazirani, Mirjana Persaud, Corey H. Yu, Dong-Hyun Kim, Raymond F. Schinazi, Dmi...> ;The Journal of Biological Chemistry. 2021 Oct 1
• 20 citations
  SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation.
  Elizabeth V. Minten, Priya Kapoor-Vazirani, Chunyang Li, Hui Zhang, Kamakshi Balakrishnan, David S. Yu> ;Cell Reports. 2021 Mar 30
• 7 citations
  Replication stress and FOXM1 drive radiation induced genomic instability and cell transformation.
  Zhentian Li, David S. Yu, Paul W. Doetsch, Erica Werner> ;Plos One. 2020 Nov 30
• 25 citations
  EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair
  Allyson E. Koyen, Matthew Z. Madden, Dongkyoo Park, Elizabeth V. Minten, Priya Kapoor-Vazirani, Erica Werner, Neil T. Pfister, Ramona Haji-Seyed-Javadi, Hui Zhang, Jie...> ;Oncogene. 2020 May 26
• 11 citations
  Ionizing Radiation induction of cholesterol biosynthesis in Lung tissue.
  Erica Werner, Andrew Alter, Qiudong Deng, Eric B. Dammer, Ya Wang, David S. Yu, Duc M. Duong, Nicholas T. Seyfried, Paul W. Doetsch> ;Scientific Reports. 2019 Aug 29
• 44 citations
  Acetylation regulates ribonucleotide reductase activity and cancer cell growth
  Guo Chen, Yin Luo, Kurt Warncke, Youwei Sun, David S. Yu, Haian Fu, Madhusmita Behera, Suresh S. Ramalingam, Paul W. Doetsch, Duc M. Duong, Michael Lammers, Walter J. ...> ;Nature Communications. 2019 Jul 19
• 31 citations
  Survival outcomes by high-risk human papillomavirus status in nonoropharyngeal head and neck squamous cell carcinomas: A propensity-scored analysis of the National Can...
  Sibo Tian, Jeffrey M. Switchenko, Jaymin Jhaveri, Richard J. Cassidy, Matthew J. Ferris, Robert H. Press, Neil T. Pfister, Mihir R. Patel, Nabil F. Saba, Mark W. McDon...> ;Cancer. 2019 Aug 15
• 22 citations
  DNA Repair: Translation to the Clinic.
  Elizabeth V. Minten, David S. Yu> ;Clinical Oncology. 2019 Mar 12
• 19 citations
  CDK9 Expression Shows Role as a Potential Prognostic Biomarker in Breast Cancer Patients Who Fail to Achieve Pathologic Complete Response after Neoadjuvant Chemotherapy.
  Ashley J. Schlafstein, Allison E. Withers, Soumon Rudra, Diana Danelia, Jeffrey M. Switchenko, Donna Mister, Saul E. Harari, Hui Zhang, Waaqo Daddacha, Shahrzad Ehdaiv...> ;International Journal of Breast Cancer. 2018 Oct 14
• 12 citations
  Disparities in Postoperative Therapy for Salivary Gland Adenoid Cystic Carcinomas
  Richard J. Cassidy, Jeffrey M. Switchenko, Mark W. El-Deiry, Ryan Belcher, Jim Zhong, Conor E. Steuer, Nabil F. Saba, Mark W. McDonald, David S. Yu, Theresa W. Gillesp...> ;The Laryngoscope. 2019 Feb 1
• 39 citations
  Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy
  Guo Chen, Andrew T. Magis, Ke Xu, Dongkyoo Park, David S. Yu, Taofeek K. Owonikoko, Gabriel Sica, Sarah W. Satola, Suresh S. Ramalingam, Walter J. Curran, Paul W. Doet...> ;The Journal of Clinical Investigation. 2017 Dec 11
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Journal Articles

• Ultrasonic Nakagami-parameter characterization of parotid-gland injury following head-and-neck radiotherapy: a feasibility study of late toxicity  
  Yang, X., Tridandapani, S., Beitler, J.J., Yu, D.S., Wu, N., Wang, Y., Bruner, D.W., Curran, W.J., Liu, T., Medical Physics, 1/1/2014
• Indocyanine green loaded liposome noncarriers for photodynamic therapy using human triple negative breast cancer cells  
  Shemesh, C.S., Hardy, C.W., Yu, D.S., Fernandez, B., Zhang, H., Photodiagnosis and Photodynamic Therapy, 1/1/2014
• CHD7 expression predicts survival outcomes in patients with resected pancreatic cancer  
  Colbert, L.E., Petrova, A.V., Fisher, S.B., Pantazides, B.G., Madden, M.Z., Hardy, C.W., Warren, M.D., Pan, Y., Nagaraju, G.P., Liu, E.A., Saka, B., Hall, W.A., Shelto..., Cancer Research, 1/1/2014
• Diagnostic accuracy of ultrasonic histogram features to evaluate radiation toxicity of the parotid glands: A clinical study of xerostomia following head-and-neck cance...  
  Yang, X., Tridandapani, S., Beitler, J.J., Yu, D.S., Chen, Z., Kim, S., Bruner, D.W., Curran, W.J., Liu, T., Academic Radiology, 1/1/2014
• A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response  
  Smith, S.C., Petrova, A.V., Madden, M.Z., Wang, H., Pan, Y., Warren, M.D., Hardy, C.W., Liang, D., Liu, E.A., Robinson, M.H., Rudra, S., Wang, J., Ehdaivand, S., Torre..., Nucleic Acids Research, 1/1/2014
• Distinct roles of Ape1 protein, an enzyme involved in DNA Repair, in high or low linear energy transfer ionizing radiation-induced cell killing  
  Wang, H., Wang, X., Chen, G., Zhang, X., Tang, X., Park, D., Cucinotta, F.A., Yu, D.S., Deng, X., Dynan, W.S., Doetsch, P.W., Wang, Y., Biological Chemistry, 1/1/2014
• Segmentation editing improves efficiency while reducing inter-expert variation and maintaining accuracy for normal brain tissues in the presence of space-occupying les...  
  Deeley, M.A., Chen, A., Datteri, R.D., Noble, J., Cmelak, A., Donnelly, E., Malcolm, A., Moretti, L., Jaboin, J., Niermann, K., Yang, E.S., Yu, D.S., Dawant, B.M., Physics in Medicine and Biology, 1/1/2013
• Pro-necrotic mixed lineage kinase domain-like (MLKL) protein expression is a prognostic biomarker in patients with early-stage resected pancreatic adenocarcinoma  
  Colbert, L.E., Fisher, S.B., Hardy, C.W., Hall, W.A., Saka, B., Shelton, J.W., Petrova, A.V., Warren, M.D., Pantazides, B.G., Gandhi, K., Kowalski, J, Kooby, D.A., El-..., Cancer, 1/1/2013
• SIRT2 directs the replication stress response through CDK9 deacetylation  
  Zhang, H., Park, S.H., Pantazides, B.G., Karpiuk, O., Warren, M.D., Hardy, C.W., Duong, D.M., Park, S.J, Kim, H.S., Vassilopoulos, A., Seyfried, N.T., Johnsen, S.A., G..., PNAS, 1/1/2013
• One stone two birds: CDK9-directed activation of UBE2A regulates monoubiquitination of both H2B and PCNA  
  Zhang, H., Yu, D.S., Cell Cycle, 1/1/2012
• Ultrasound histogram assessment of parotid gland injury following head and neck radiotherapy: a feasibility study  
  Yang, X., Tridandapani, S., Beitler, J.J., Yu, D.S., Yoshida, E.J., Curran, W.J., Liu, T., Ultrasound in Medicine and Biology, 1/1/2012
• Ultrasound GLCM texture analysis in radiation-induced parotid injury in head-and-neck cancer radiotherapy: an in vivo study of late toxicity  
  Yang, X., Tridandapani, S., Beitler, J.J., Yu, D.S., Yoshida, E.J., Chen, H., Curran, W.J., Liu, T., Medical Physics, 1/1/2012
• A role for cdk9-cyclin k in maintaining genome integrity  
  Yu, D.S. and Cortez, D., Cell Cycle, 1/1/2011
• The negative effect of triple negative breast cancer on outcome after breast conserving therapy  
  Zaky, S.S., Lund, M., May, K.A., Godette, K.D., Beitler, J.J., Holmes, L.R., O'Regan, R.M., Yu, E.S., Yu, D.S., and Landry, J.C., Annals Of Surgical Oncology, 1/1/2011
• Comparison of manual and automatic segmentation methods for brain structures in the presence of space-occupying lesions: a multi-expert study  
  Deeley, M.A., Chen, A., Daterri, R., Noble, J.H., Cmelak, A.J., Donnelly, E.F., Malcolm, A.W., Moretti, L., Jaboin, J., Niermann, K., Yang, E.S., Yu, D.S., Yei, F., Ko..., Physics in Medicine and Biology, 1/1/2011
• Cyclin-dependent kinase 9-cyclin K functions in the replication stress response  
  Yu, D.S., Zhao, R., Hsu, E.L., Cayer, J., Ye, F., Guo, Y., Shyr, Y., and Cortez, D., EMBO R, 1/1/2010
• Prognostic factors for resected non-small cell lung cancer with pN2 status: implications for use of postoperative radiotherapy  
  Yu, D.S., Moretti, L., Chen, H., Carbone, D.P., Johnson, D.H., Keedy, V.L., Putnam, J., Sandler, A.B., Shyr, Y., and Lu, B., Oncologist, 1/1/2009
• A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair  
  Matsushita, N., Kitao, H., Ishiai, M., Nagashima, N., Hirano, S., Okawa, K., Ohta, T., Yu, D.S., McHugh P.J., Hickson, I.D., Venkitaraman, A.R., Kurumizaka, H., Takata..., Molecular Cell, 1/1/2005
• EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer  
  Hughes-Davies, L., Huntsman, D., Ruas, M., Fuks, F., Bye, J., Chin, S.F., Milner, J., Brown, L.A., Hsu, F., Gilks, B., Nielsen, T., Schulzer, M., Chia, S., Ragaz, J., ..., Cell, 1/1/2004
• Dynamic control of RAD51 recombinase by self-association and interaction with BRCA2  
  Yu, D.S., Sonoda, E., Takeda, S., Pellegrini L., Huang, C.L., Blundell, T.L., Venkitaraman A.R., Molecular Cell, 1/1/2003
• Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2  
  Shin, D.S., Pellegrini, L., Daniels, D., Yelent, B., Craig, L., Tsurata, H., Bates, D., Yu, D.S., Shivji, M.K., Hitomi, C., Arvai, A.S., Blundell, T.L., Venkitaraman, ..., EMBO J, 1/1/2003
• Insights into DNA recombination from the structure of a RAD51-BRCA2 complex  
  Pellegrini, L., Yu, D.S., Lo, T., Anand, S., Lee, M., Blundell, T.L., Venkitaraman, A.R., Nature, 1/1/2002
• A functional comparison of BRCA1 C-terminal domains in transcription activation and chromatin remodeling  
  Miyake, T., Hu, Y.H., Yu, D.S., Li, R., Journal of Biological Chemistry, 1/1/2000
• Activation of chromosomal DNA replication in Saccharomyces cerevisiae by acidic transcriptional activation domains  
  Li, R., Yu, D.S., Tanaka, M., Zheng, L., Berger, S., Stillman, B., Molecular and Cellular Biology, 1/1/1998
• Association of a 14-3-3 protein with CMP-NeuAc:GM1 a2,3-Sialyltransferase  
  Gao, L., Gu, X., Yu, D.S., Yu, R.K., Zeng, G., Biochemical and Biophysical Research Communications, 1/1/1996
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Abstracts/Posters

• Gaussian Mixture Model Analysis of Radiation-Induced Parotid-Gland Injury: An Ultrasound Study of Acute and Late Xerostomia in Head and Neck Radiotherapy.
  Liu, T., Beitler, J.J., Yu, D.S., Tridandapani, S., Curran, W.J., Yang, X., American Association of Physicists in Medicine Annual Meeting, Austin, TX, 1/1/2014
• A siRNA Chemotherapeutic Sensitivity Screen in Small Cell Lung Cancer Cells Identifies Potential DNA Damage Response Genes for Improved Clinical Outcome.
  Madden, M.Z, Yu, D.S., Radiation Research Society Annual Meeting, Las Vegas, NM, 1/1/2014
• A Gemcitabine Sensitivity Screen identifies a Role for NEK9 in the Replication Stress Response.
  Petrova, A.V., Smith, S.C., Madden, M.Z., Wang, H., Pan, Y., Warren, M.D., Hardy, C.W., Liang, D., Liu, E.A., Robinson, M.H., Rudra, S., Wang, J., Ehdaivand, S., Torre..., Radiation Research Society Annual Meeting, Las Vegas, NM, 1/1/2014
• Locoregional Recurrent Patterns in Young Versus Elderly Women Treated for Breast Cancer.
  Rudra, S., Yu, D.S., Yu, E.S., Switchenko, J.M., Mister, D., Torres, M.A., Radiation Research Society Annual Meeting, Las Vegas, NM, 1/1/2014
• TNFRSF10C Copy Number Variation is Associated with Metastatic Colorectal Cancer.
  Tannenbaun, D., Hall, W.A., Colbert, L.E., Brat, D.J., Kong, J., Kim, S., Dwivedi, B., Kowalski, J., Landry, J., Yu, D.S., Radiation Research Society Annual Meeting, Las Vegas, NM, 1/1/2014
• SIRT2 directs the replication stress response through CDK9 deacetylation.
  Zhang, H., Park, S.H., Pantazides, B.G., Karpiuk, O., Hardy, C.W., Duong, D.M., Park, S., Kim, H., Vassilopoulos, A., Seyfried, N.T., Johnsen, S.A., Gius, D., Yu, D.S., Keystone Meeting on Genome Instability and DNA Repair, Banff, CA, 1/1/2013
• A synthetic lethal screen identifies determinants of gemcitabine sensitivity in pancreatic cancer.
  Warren, M.D., Hardy, C.W., Pantazides, B.G., Landry, J.C., Shelton, J.W., Maithel, S.K., El-Rayes, B., Kowalski, J, Yu, D.S., AACR Annual Meeting, Washington, DC, 1/1/2013
• A pilot clinical trial of chromodomain-helicase-DNA-binding protein 7 (CHD7) expression as a prognostic and predictive biomarker in patients with early-stage pancreati...
  Colbert, L.C., Hall, W.A., Hardy, C.W., Fisher, S.B., Yu, D.S., Maithel, S.K., El-Rayes, B., Saka, B., Adsay, N.V., Petrova, A., Pantazides, B., Kowalski, J., Gandhi, ..., AACR Annual Meeting, Washington, DC, 1/1/2013
• Understanding and exploiting the replication stress response in pancreatic cancer.
  Colbert, L.E., Fisher, S.B., Hardy, C.W., Hall, W.A., Saka, B., Shelton, J.W., Petrova, A.V., Warren, M.D., Pantazides, B.G., Gandhi, K., Kowalski, J, Kooby, D.A., El-..., AACR Annual Meeting, Washington, DC, 1/1/2013
• Ultrasound for diagnostic imaging.
  Liu, T., Yu, D.S., Beitler, J., Tridandapani, S., Bruner, D., Curran, W.J., Yang, X., AAPM Annual Meeting, Indianapolis, IN, 1/1/2013
• SIRT2 directs the replication stress response by activating CDK9 through deacetylation.
  Zhang, H., Park, S.H., Pantazides, B.G., Karpiuk, O., Hardy, C.W., Duong, D.M., Park, S., Kim, H., Vassilopoulos, A., Seyfried, N.T., Johnsen, S.A., Gius, D., Yu, D.S., Radiation Research Society Annual Meeting, New Orleans, LA, 1/1/2013
• A rationale-driven approach using a gemcitabine sensitivity screen identifies CHD7 expression as a predictor of outcome in patients with resected pancreatic cancer.
  Colbert, L.E., Fisher, S.B., Hardy, C.W., Hall, W.A., Saka, B., Shelton, J.W., Petrova, A.V., Warren, M.D., Pantazides, B.G., Gandhi, K., Kowalski, J, Kooby, D.A., El-..., Radiation Research Society Annual Meeting, New Orleans, LA, 1/1/2013
• A synthetic lethal screen identifies determinants of gemcitabine sensitivity in pancreatic cancer.
  Petrova, A.V., Colbert, L.E., Fisher, S.B., Hardy, C.W., Hall, W.A., Saka, B., Shelton, J.W., Warren, M.D., Pantazides, B.G., Gandhi, K., Kowalski, J, Kooby, D.A., El-..., Radiation Research Society Annual Meeting, New Orleans, LA, 1/1/2013
• Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer.
  Hall, W.A., Petrova, A.V., Colbert, L.E., Hardy, C.W., Fisher, S.B., Saka, B., Shelton, J.W., Warren, M.D., Pantazides, B.G., Gandhi, K., Kowalski, J., Kooby, D.A., El..., Radiation Research Society Annual Meeting, New Orleans, LA, 1/1/2013
• A rationale-driven approach using a gemcitabine sensitivity screen identifies CHD7 expression as a predictor of outcome in patients with resected pancreatic cancer.
  Colbert, L.E., Fisher, S.B., Hardy, C.W., Hall, W.A., Saka, B., Shelton, J.W., Petrova, A.V., Warren, M.D., Pantazides, B.G., Gandhi, K., Kowalski, J, Kooby, D.A., El-..., American Society for Therapeutic Radiology and Oncology (ASTRO) 55th Annual Meeting, Atlanta, GA, 1/1/2013
• Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer.
  Hall, W.A., Petrova, A.V., Colbert, L.E., Hardy, C.W., Fisher, S.B., Saka, B., Shelton, J.W., Warren, M.D., Pantazides, B.G., Gandhi, K., Kowalski, J., Kooby, D.A., El..., American Society for Therapeutic Radiology and Oncology (ASTRO) 55th Annual Meeting, Atlanta, GA, 1/1/2013
• Pro-necrotic mixed lineage kinase domain-like (MLKL) protein expression is a prognostic biomarker in patients with early-stage resected pancreatic adenocarcinoma.
  Fisher, S.B., Colbert, L.E., Hardy, C.W., Hall, W.A., Saka, B., Shelton, J.W., Petrova, A.V., Warren, M.D., Pantazides, B.G., Gandhi, K., Kowalski, J, Kooby, D.A., El-..., American Society for Therapeutic Radiology and Oncology (ASTRO) 55th Annual Meeting, Atlanta, GA, 1/1/2013
• Rationale-Driven Identification of Novel Gemcitabine Sensitivity Genes as Biomarkers for Outcome in Pancreatic Cancer Patients by Exploiting the Replication Stress Res...
  Colbert, L.E., Fisher, S.B., Hardy, C.W., Hall, W.A., Saka, B., Shelton, J.W., Petrova, A.V., Warren, M.D., Pantazides, B.G., Gandhi, K., Kowalski, J, Kooby, D.A., El-..., 3rd World Congress on Cancer Science and Therapy, San Francisco, CA, 1/1/2013
• A synthetic lethal screen identifies genetic determinants for gemcitabine sensitivity in pancreatic cancer.
  Landry, J.C., Pantazides, B.G., Park, W., Shelton, J.W., Maithel, S.K., El-Rayes, B., Yu, D.S., American Association for Cancer Research (AACR) Annual Meeting, Chicago, IL, 1/1/2012
• Sonographic features assessment of parotid-gland injury following head and neck radiotherapy.
  Yang, X., Beitler, J.J., Yu, D.S., Tridandapani, S., Curran, W.J., Liu, T., Winship Scientific Research and Academic Development Symposium, Atlanta, GA, 1/1/2012
• A synthetic lethal screen identifies genes that mediate gemcitabine resistance in pancreatic cancer.
  Pantazides, B.G., Hardy, C.W., Gandhi, K., Landry, J., Shelton, J., Maithel, S., El-Rayes B., Kowalski, J., Yu, D.S., Winship Scientific Research and Academic Development Symposium, Atlanta, GA, 1/1/2012
• SIRT2 directs the replication stress response through CDK9 deacetylation.
  Zhang, H., Park, S.H., Pantazides, B.G., Hardy, C.W., Duong, D.M., Seyfried, N.T., Gius, D., Yu, D.S., Winship Scientific Research and Academic Development Symposium, Atlanta, GA, 1/1/2012
• SIRT2 directs the replication stress response through CDK9 deacetylation.
  Zhang, H., Park, S.H., Pantazides, B.G., Hardy, C.W., Duong, D.M., Seyfried, N.T., Gius, D., Yu, D.S., Emory University School of Medicine Postdoctoral Symposium, Atlanta, GA, 1/1/2012
• A loss of function genetic screen identifies determinants of gemcitabine sensitivity in pancreatic cancer.
  Hardy, C.W., Pantazides, B.G., Gandhi, K., Landry, J., Shelton, J., Maithel, S., El-Rayes B., Kowalski, J., Yu, D.S., AACR/Pancreatic Cancer: Progress and Challenges Meeting, Lake Tahoe, NV, 1/1/2012
• A loss of function genetic screen identifies determinants of gemcitabine sensitivity in pancreatic cancer.
  Hardy, C.W., Pantazides, B.G., Gandhi, K., Shelton, J., Maithel, S., El-Rayes B., Kowalski, J., Yu, D.S., Landry, J., International Society of Gastrointestinal Oncology Meeting, Washington, DC, 1/1/2012
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Lectures

• "Role of SIRT2 in the Replication Stress Response" 
  1/1/2014
• "Functions of SIRT2 in the Replication Stress Response" Cancer Genetics and Epigenetics Program Speaker 
  1/1/2014
• "Functions of SIRT2 in the Replication Stress Response" 
  Las Vegas, NM - 1/1/2014
• "Pancreatic Cancer Research and Challenges" 
  1/1/2013
• "Cancer Therapeutics and Diagnostics" 
  1/1/2013
• "Understanding and Exploiting the Replication Stress Response in Pancreatic Cancer" 
  Washington, DC - 1/1/2013
• "Biomarker Analysis of Gemcitabine Sensitivity Genes in Pancreatic Cancer" 
  Philadelphia, PA - 1/1/2013
• "Rationale-Driven Identification of Novel Gemcitabine Sensitivity Genes as Biomarkers for Outcome in Pancreatic Cancer Patients by Exploiting the Replication Stress Re... 
  San Francisco, CA - 1/1/2013
• "The Replication Stress Response in Head and Neck Cancer" 
  1/1/2012
• "DNA Repair in Triple-Negative Breast Cancer" 
  1/1/2012
• Winship Cancer Institute Grand Rounds: "Role of SIRT2 in the Replication Stress Response: A Link Between Aging and Breast Cancer" 
  Emory University School of Medicine - 1/1/2012
• "Exploiting the Replication Stress Response in Pancreatic Cancer" 
  Los Angeles, CA - 1/1/2012
• "Understanding and Exploiting the Replication Stress Response in Cancer" 
  1/1/2011
• "CDK9-Cyclin K Functions in the Replication Stress Response" 
  Washington, DC - 1/1/2011
• "A Loss of Function Screen Identifies CDK9 as a Novel Replication Stress Response Protein" 
  Washington, DC - 1/1/2010
• "The Replication Stress Response in Cancer" 
  1/1/2009
• "A Synthetic Lethal Screen Identifies CDK9 as a Novel Replication Stress Response Protein" 
  1/1/2009
• "The Replication Stress Response in Cancer," 
  1/1/2009
• "Role of CDK9 in the Replication Stress Response" 
  Vanderbilt University Medical Center, Nashville, TN - 1/1/2008
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