DeanFrederickMacKinnonMD

Psychiatry • Baltimore, MD

Associate Professor of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine

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Office
600 N. Wolfe Street
Meyer Building, Suite 3-181
Baltimore, MD 21287
Phone+1 410-955-5212

Fax+1 410-955-0152
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Summary

Dr. Dean MacKinnon is a psychiatrist in Baltimore, MD and an associate professor on the faculty of the Department of Psychiatry and Behavioral Sciences in the Johns Hopkins University School of Medicine, where he trained in psychiatry after graduating from University of California School of Medicine in 1990.

He is the author or co-author of numerous journal articles and book chapters, and the solo author of two books: Trouble in Mind: An unorthodox introduction to psychiatry (2011) and Still Down: What to do when antidepressants fail (2016).

Clinical expertise is in mood disorders that have responded poorly to treatment.

Education & Training

Johns Hopkins UniversityResidency, Psychiatry, 1990 - 1994
University of California San Diego School of MedicineClass of 1990

Certifications & Licensure

FL State Medical License 2021 - Present
MD State Medical License 1991 - 2025
American Board of Psychiatry and Neurology Psychiatry

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013-2014

Publications & Presentations

PubMed

Identifying genetic differences between bipolar disorder and major depression through multiple GWAS.
Panagiotaropoulou, G., Hellberg, K., Coleman, J., Seok, D., Kalman, J., , , , Mitchell, P., Schofield, P., Forstner, A., Bauer, M., Scott, L., Pato, C., Pato, M., Li, ...> ;Medrxiv. 2024 Jan 30
1 citations
A Role for Psychiatry in the Personalized Medicine Curriculum.
Dean F MacKinnon, Emily Frosch> ;Academic Psychiatry. 2022 Jun 1
1 citations
Correction : Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (Molecular Psychiatry, (2020)...
Jri Coleman, Kirstin L. Purves, Kas Davis, Christopher Rayner, Shing Wan Choi, Christopher Hübel, Helena Gaspar, Carol Kan, Van der Auwera S, Mark Adams, Donald M. Lya...> ;Molecular Psychiatry. 2021 Sep 1
3 citations
The Care of Patients With Complex Mood Disorders.
Zachary A. Cordner, Dean F. MacKinnon, J. Raymond DePaulo> ;Focus. 2020 Apr 24
19 citations
Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression
Kylie P. Glanville, Jonathan R. I. Coleman, Ken B. Hanscombe, Jack Euesden, Shing Wan Choi, Kirstin L. Purves, Gerome Breen, Tracy Air, Till F. M. Andlauer, Bernhard T...> ;Biological Psychiatry. 2020 Mar 1
14 citations
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder
Simone de Jong, Mateus Jose Abdalla Diniz, Andiara Calado Saloma Rodrigues, Ary Gadelha, Marcos L. Santoro, Vanessa Kiyomi Ota, Cristiano Noto, Charles Curtis, Stephen...> ;Communications Biology. 2018 Oct 8
1583 citations
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Naomi R. Wray, Stephan Ripke, Manuel Mattheisen, Maciej Trzaskowski, Enda M. Byrne, Abdel Abdellaoui, Mark Adams, Esben Agerbo, Tracy Air, Till M.F. Andlauer, Silviu A...> ;Nature Genetics. 2018 Apr 26
18 citations
Change in Medical Student Attitudes Toward Patients with Substance Use Disorders After Course Exposure
Makeida B. Koyi, Archana Nelliot, Dean F. MacKinnon, Darius A. Rastegar, Michael Fingerhood, Anika A.H. Alvanzo, Leonard Feldman, Karin J. Neufeld> ;Academic Psychiatry. 2018 Apr 1
29 citations
Distinguishing bipolar from unipolar depression: the importance of clinical symptoms and illness features
A K Leonpacher, David T. Liebers, Mehdi Pirooznia, Dubravka Jancic, Dean F. MacKinnon, Francis M. Mondimore, Barbara W. Schweizer, James B. Potash, Peter P. Zandi, Fer...> ;Psychological Medicine. 2015 Aug 1
121 citations
Type I interferon signaling genes in recurrent major depression: increased expression detected by whole-blood RNA sequencing.
Sara Mostafavi, Alexis Battle, Xiaowei Zhu, James B. Potash, Myrna M. Weissman, Jianxin Shi, Kenneth B. Beckman, Christian D. Haudenschild, Courtney McCormick, R Mei, ...> ;Molecular Psychiatry. 2014 Dec 1
3 citations
Delirium Presenting as Mania in a Patient With End-Stage COPD
Samuel T. Wilkinson, Shin Bey Chang, Teresa Foley, John R. Lipsey, Dean F. MacKinnon> ;The American Journal of Psychiatry. 2014 Aug 1
38 citations
Posttraumatic stress disorder increases risk for suicide attempt in adults with recurrent major depression
Daniel A. Stevens, Holly C. Wilcox, Dean F. MacKinnon, Francis M. Mondimore, Barbara Schweizer, Dunya Jancic, William Coryell, Myrna M. Weissman, Douglas F. Levinson, ...> ;Depression and Anxiety. 2013 Oct 1
A family tree filled with mental illness: review: a lethal inheritance: a mother uncovers the science behind three generations of mental illness by victoria costello.
Dean F Mackinnon> ;Cerebrum. 2012 May 1
109 citations
A genome-wide association study of attempted suicide
Virginia L. Willour, Fayaz Seifuddin, Pamela B. Mahon, Dubravka Jancic, Mehdi Pirooznia, Jo Steele, Barbara W. Schweizer, Fernando S. Goes, Francis M. Mondimore, Dean ...> ;Molecular Psychiatry. 2012 Apr 1
91 citations
Co-morbid anxiety disorders in bipolar disorder and major depression: familial aggregation and clinical characteristics of co-morbid panic disorder, social phobia, spe...
Fernando S. Goes, Michael G. McCusker, Oscar J. Bienvenu, Dean F. MacKinnon, Francis M. Mondimore, Barbara W. Schweizer, J. R. DePaulo, James B. Potash> ;Psychological Medicine. 2012 Jul 1
16 citations
A Collaborative Approach to Teaching Medical Students How to Screen, Intervene, and Treat Substance Use Disorders
Karin J. Neufeld, Anika A.H. Alvanzo, Van L. King, Leonard Feldman, Jeffrey Hsu, Darius A. Rastegar, Jorie Colbert, Dean F. MacKinnon> ;Substance Abuse. 2012 Jun 27
15 citations
Association study of serotonin pathway genes in attempted suicide
Jennifer Toolan Judy, Fayaz Seifuddin, Pamela B. Mahon, Yuqing Huo, Fernando S. Goes, Dubravka Jancic, Barbara W. Schweizer, Francis M. Mondimore, Dean F. MacKinnon, J...> ;American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 2012 Jan 1
9 citations
Genetic association of bipolar disorder with the β3 nicotinic receptor subunit gene
Sarah M. Hartz, Peng Lin, Howard J. Edenberg, Xiaoling Xuei, Nanette Rochberg, Scott F. Saccone, Wade H. Berrettini, Elliot C. Nelson, John I. Nurnberger, Laura J. Bie...> ;Psychiatric Genetics. 2011 Apr 1
48 citations
Sex‐specific association of the reelin gene with bipolar disorder
Fernando S. Goes, Virginia L. Willour, Peter P. Zandi, Pamela L. Belmonte, Dean F. MacKinnon, Francis M. Mondimore, Barbara W. Schweizer, J. R. DePaulo, Elliot S. Gers...> ;American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 2010 Mar 5
64 citations
Genome-Wide Linkage and Follow-Up Association Study of Postpartum Mood Symptoms
Pamela B. Mahon, Jennifer L. Payne, Dean F. MacKinnon, Francis M. Mondimore, Fernando S. Goes, Barbara W. Schweizer, Dubravka Jancic, William Coryell, Peter Holmans, J...> ;The American Journal of Psychiatry. 2009 Nov 1
25 citations
Family-based association study of Neuregulin 1 with psychotic bipolar disorder.
Fernando S. Goes, Virginia L. Willour, Peter P. Zandi, Pamela L. Belmonte, Dean F. MacKinnon, Francis M. Mondimore, Barbara W. Schweizer, Elliot S. Gershon, Francis J....> ;American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 2009 Jul 5
116 citations
Family-based association of FKBP5 in bipolar disorder.
Virginia L. Willour, H Chen, Jennifer Toolan, Pamela L. Belmonte, David J. Cutler, Fernando S. Goes, Peter P. Zandi, Richard S. Lee, Dean F. MacKinnon, Francis M. Mond...> ;Molecular Psychiatry. 2009 Jan 1
11 citations
Premenstrual mood symptoms: study of familiality and personality correlates in mood disorder pedigrees.
Jennifer L. Payne, Sarah R. Klein, Rachel B. Zamoiski, Peter P. Zandi, Oscar J. Bienvenu, Dean F. MacKinnon, Francis M. Mondimore, Barbara W. Schweizer, Karen Swartz, ...> ;Archives of Women's Mental Health. 2009 Jan 10
41 citations
Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder
Lixiang Liu, Tatiana Foroud, Xiaoling Xuei, Wade H. Berrettini, William Byerley, William Coryell, Rif S. El-Mallakh, Elliot S. Gershon, John R. Kelsoe, William Lawson,...> ;Psychiatric Genetics. 2008 Dec 1
9 citations
Rapid switching of mood in families with familial bipolar disorder
Evaristus A. Nwulia, Peter P. Zandi, Melvin G. McInnis, J. Raymond DePaulo, Dean F. MacKinnon> ;Bipolar Disorders. 2008 Aug 1
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Books/Book Chapters

Still Down: What to do when antidepressants fail
Dean F MacKinnonJohns Hopkins University Press, Baltimore2016
Trouble in Mind: An unorthodox introduction to psychiatry
Dean F. MacKinnonJohns Hopkins University Press, Baltimore2011

Press Mentions

Depression Biomarkers: Which Ones Matter Most?May 4th, 2022
After Pennsylvania Mom's Frozen Trek, Experts Share Wilderness Survival TipsDecember 27th, 2016
10-Minute Total-Body Toning WorkoutDecember 27th, 2016
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