Deborah Phyllis Merke MD MS

Pediatric Bone Metabolism Disorders

Senior Investigator and Chief of Pediatric Services at the NIH Clinical Center

Nih Clinical CtrBuilding 10 CRC Room 12740Bethesda, MD 20892
Phone+1 301-496-0718
Fax+1 301-402-5618

Dr. Merke is on Doximity

As a Doximity member, you’ll join more than three million U.S. healthcare professionals—including 85+% of physicians, and 2/3 of all NPs and PAs—in a private, secure network.

Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
Connect with colleagues in the same hospital or clinic.
Read the latest clinical news, personalized to your specialty.

See Dr. Merke's full profile Already have an account?

Education & Training

National Institutes of Health Clinical Center/Eunice Kennedy Shriver NICHDFellowship, Pediatric Endocrinology, 1994 - 1997
Children's Hospital of PhiladelphiaResidency, Pediatrics, 1991 - 1994
Jacobs School of Medicine and Biomedical Sciences at the University at BuffaloClass of 1991

The following disclaimer is related to board certifications obtained from ABMS®, denoted by the ABMS® logo.

This information is proprietary data maintained in a copyrighted database owned by the American Board of Medical Specialties®. The display and presence of ABMS Data in no way constitutes any affiliation, association with, or endorsement of any advertising, promotion, or sponsorship by ABMS and its affiliates and subsidiaries, the ABMS Member Boards, or ABMS board certified physicians and medical specialists. Copyright 2026 American Board of Medical Specialties®. All rights reserved.

The user is responsible for ensuring that the profile obtained in this directory is the profile of the physician or medical specialist being sought.

A self-designated specialty, subspecialty, or practice area neither implies nor is equivalent to ABMS board certification or the existence of specialized training by or competence of a physician or medical specialist.

Certifications & Licensure

MD State Medical License 1995 - 2027
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Endocrinology

Clinical Trials

Three Drug Combination Therapy Versus Conventional Treatment of Children With Congenital Adrenal Hyperplasia Start of enrollment: 1995 Jun 08
COMPLETED
PHASE3
Natural History Study of Patients With Excess Androgen Start of enrollment: 2006 Jan 02
RECRUITING
Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia Start of enrollment: 2013 May 06
COMPLETED
PHASE2

Publications & Presentations

PubMed

The evolution of new approaches to the treatment of congenital adrenal hyperplasia.
Deborah P Merke, Richard J Auchus
Endocrine Reviews. 2026-08-25
Glucocorticoid reduction after starting crinecerfont in pediatric patients with classic congenital adrenal hyperplasia: practical perspectives.
Natalie J Nokoff, Patricia Y Fechner, Mimi S Kim, Ian Marshall, Deborah P Merke
The Journal of Clinical Endocrinology and Metabolism. 2026-07-15
2 citations
The Importance of Disease-specific Growth Charts for Children with Congenital Adrenal Hyperplasia.
Kyriakie Sarafoglou, Yesica Mercado Munoz, Charles Sukin, Aida Lteif, Jennifer Kyllo
The Journal of Clinical Endocrinology and Metabolism. 2026-03-17

Journal Articles

Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society Clinical Practice Guideline
Sharon E Oberfield, Walter L Miller, Perrin C White, Deborah P Merke, Richard J Auchus, The Journal of Clinical Endocrinology and Metabolism
Long‐Term Use of Continuous Subcutaneous Hydrocortisone Infusion Therapy in Patients with Congenital Adrenal Hyperplasia
Ashwini Mallappa, Aikaterini A Nella, Deborah P Merke, Clinical Endocrinology

Lectures

Rethinking Adrenal Androgens in Physiology and Disease
ENDO 2019 - New Orleans, LA - 3/24/2019
Transition, New Insights into Etiology, and Prescriptions
ENDO 2019 - New Orleans, LA - 3/26/2019
Transition, New Insights into Etiology, and Prescriptions (Repeat)
ENDO 2019 - New Orleans, LA - 3/26/2019

Other

Diagnosis of classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Merke DP
http://www.uptodate.com/contents/diagnosis-of-classic-congenital-adrenal-hyperplasia-due-to-21-hydro
UpToDate, Wolters Kluwer Health - 2012-08-02
Genetics and clinical presentation of classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Merke DP
http://www.uptodate.com/contents/genetics-and-clinical-presentation-of-classic-congenital-adrenal-hy
UpToDate, Wolters Kluwer Health - 2013-04-04
Treatment of classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency in infants and children
Merke DP
http://www.uptodate.com/contents/treatment-of-classic-congenital-adrenal-hyperplasia-due-to-21-hydro
UpToDate, Wolters Kluwer Health - 2012-12-12

Press Mentions

Classic Congenital Adrenal Hyperplasia: Understanding Treatment OptionsAugust 8th, 2025
What to Do During a Classic CAH Adrenal CrisisAugust 8th, 2025
Tenascin-X—Discovery and Early ResearchJanuary 11th, 2021