DebraNewmanMD

PubMed

• 68 citations
  CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1
  K.W. Huynh, Jiansen Jiang, Natalia Abuladze, Kirill Tsirulnikov, Liyo Kao, Xuesi M. Shao, D. Newman, Rustam Azimov, Alexander Pushkin, Z.H. Zhou, Ira Kurtz> ;Nature Communications. 2018 Mar 2
• 22 citations
  The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Fun...
  Panida Lertkiatmongkol, Cathy Paddock, Debra K. Newman, Jieqing Zhu, Michael J. Thomas, Peter J. Newman> ;The Journal of Biological Chemistry. 2016 Dec 9
• 31 citations
  Multifunctional ion transport properties of human SLC4A11: comparison of the SLC4A11-B and SLC4A11-C variants
  Liyo Kao, Rustam Azimov, Xuesi M. Shao, Ricardo F Frausto, Natalia Abuladze, Debra K. Newman, Anthony J. Aldave, Ira Kurtz> ;American Journal of Physiology. Cell Physiology. 2016 Aug 31
• 8 citations
  Interplay between disulfide bonding and N-glycosylation defines SLC4 Na+-coupled transporter extracellular topography.
  Quansheng Zhu, Liyo Kao, Rustam Azimov, Natalia Abuladze, Debra K. Newman, Ira Kurtz> ;The Journal of Biological Chemistry. 2015 Feb 27
• 36 citations
  Human SLC4A11-C functions as a DIDS-stimulatable H+(OH−) permeation pathway: partial correction of R109H mutant transport
  Liyo Kao, Rustam Azimov, Natalia Abuladze, Debra K. Newman, Ira Kurtz> ;American Journal of Physiology. Cell Physiology. 2015 Jan 15
• 26 citations
  Missense mutation T485S alters NBCe1-A electrogenicity causing proximal renal tubular acidosis.
  Quansheng Zhu, Xuesi M. Shao, Liyo Kao, Rustam Azimov, Alan M. Weinstein, Debra K. Newman, Weixin Liu, Ira Kurtz> ;American Journal of Physiology. Cell Physiology. 2013 Aug 15
• 15 citations
  Topology of NBCe1 protein transmembrane segment 1 and structural effect of proximal renal tubular acidosis (pRTA) S427L mutation.
  Quansheng Zhu, Weixin Liu, Liyo Kao, Rustam Azimov, Debra K. Newman, Natalia Abuladze, Ira Kurtz> ;The Journal of Biological Chemistry. 2013 Mar 15
• 13 citations
  Integrin αIIbβ3 inside-out activation: an in situ conformational analysis reveals a new mechanism.
  Lisa Kurtz, Liyo Kao, Debra K. Newman, Ira Kurtz, Quansheng Zhu> ;The Journal of Biological Chemistry. 2012 Jun 29
• 48 citations
  Severe Neurologic Impairment in Mice with Targeted Disruption of the Electrogenic Sodium Bicarbonate Cotransporter NBCe2 (Slc4a5 Gene)
  Liyo Kao, Lisa M. Kurtz, Xuesi Shao, Marios C. Papadopoulos, Li Liu, Dean Bok, Steven Nusinowitz, Bryan Chen, Salvatore L. Stella, Mark Andre, Josh Weinreb, Serena S. ...> ;The Journal of Biological Chemistry. 2011 Sep 16
• 25 citations
  Structural and Functional Characterization of the C-terminal Transmembrane Region of NBCe1-A
  Quansheng Zhu, Liyo Kao, Rustam Azimov, Natalia Abuladze, Debra K. Newman, Alexander Pushkin, Weixin Liu, Connie B. Chang, Ira Kurtz> ;The Journal of Biological Chemistry. 2010 Nov 26
• 28 citations
  Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2...
  Leonardo A. Moraes, Natasha E. Barrett, Chris I. Jones, Lisa-Marie Holbrook, M. Spyridon, Tanya Sage, Debra K. Newman, Jonathan M. Gibbins> ;Journal of Thrombosis and Haemostasis. 2010 Nov 1
• PECAM-1 functions as a negative regulator of laminin-induced platelet activation.
  Crockett J, Newman DK, Newman PJ> ;J. Thromb. Haemost.. 2010-07-01
• 34 citations
  Topological Location and Structural Importance of the NBCe1-A Residues Mutated in Proximal Renal Tubular Acidosis
  Quansheng Zhu, Liyo Kao, Rustam Azimov, Debra K. Newman, Weixin Liu, Alexander Pushkin, Natalia Abuladze, Ira Kurtz> ;The Journal of Biological Chemistry. 2010 Apr 30
• 6 citations
  Transport of N-acetyl-S-(1,2-dichlorovinyl)-l-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2)
  Kirill Tsirulnikov, Natalia Abuladze, Myong Chul Koag, Debra K. Newman, Karoline Scholz, Galyna Bondar, Quansheng Zhu, Nuraly K. Avliyakulov, Wolfgang Dekant, Kym F. F...> ;Toxicology and Applied Pharmacology. 2010 Apr 15
• 60 citations
  Slc4a11 Gene Disruption in Mice CELLULAR TARGETS OF SENSORINEURONAL ABNORMALITIES
  Ivan A. Lopez, Mark I. Rosenblatt, Charles Kim, Gary C. Galbraith, Sherri M. Jones, Liyo Kao, Debra K. Newman, Weixin Liu, Stacey Yeh, Alexander Pushkin, Natalia Abula...> ;The Journal of Biological Chemistry. 2009 Sep 25
• 9 citations
  Mouse aminoacylase 3: A metalloenzyme activated by cobalt and nickel
  Kirill Tsirulnikov, Natalia Abuladze, Debra K. Newman, Sergey Ryazantsev, Talya Wolak, Nathaniel Magilnick, Myong Chul Koag, Ira Kurtz, Alexander Pushkin> ;Biochimica Et Biophysica Acta. 2009 Jul 1
• 15 citations
  The Y's that bind: negative regulators of Src family kinase activity in platelets.
  Debra K. Newman> ;Journal of Thrombosis and Haemostasis. 2009 Jul 1
• 26 citations
  NBCe1-A Transmembrane Segment 1 Lines the Ion Translocation Pathway
  Quansheng Zhu, Rustam Azimov, Liyo Kao, Debra K. Newman, Weixin Liu, Natalia Abuladze, Alexander Pushkin, Ira Kurtz> ;The Journal of Biological Chemistry. 2009 Mar 27
• 50 citations
  Oligomeric structure and minimal functional unit of the electrogenic sodium bicarbonate cotransporter NBCe1-A.
  Liyo Kao, Pakan Sassani, Rustam Azimov, Alexander Pushkin, Natalia Abuladze, Janos Peti-Peterdi, Weixin Liu, Debra K. Newman, Ira Kurtz> ;The Journal of Biological Chemistry. 2008 Sep 26
• 10 citations
  G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis.
  Rustam Azimov, Natalia Abuladze, Pakan Sassani, Debra K. Newman, Liyo Kao, Weixin Liu, Nicholas Orozco, Piotr Ruchala, Alexander Pushkin, Ira Kurtz> ;American Journal of Physiology. Renal Physiology. 2008 Jul 9
• 8 citations
  Structural characterization of dimeric murine aminoacylase III.
  Sergey Ryazantsev, Natalia Abuladze, Debra K. Newman, Galyna Bondar, Ira Kurtz, Alexander Pushkin> ;FEBS Letters. 2007 May 1
• 23 citations
  Specificity of aminoacylase III-mediated deacetylation of mercapturic acids.
  Debra K. Newman, Natalia Abuladze, Karoline Scholz, Wolfgang Dekant, Vladimir Tsuprun, Sergey Ryazantsev, Galyna Bondar, Pakan Sassani, Ira Kurtz, Alexander Pushkin> ;Drug Metabolism and Disposition. 2007 Jan 1
• 30 citations
  Critical amino acid residues involved in the electrogenic sodium-bicarbonate cotransporter kNBC1-mediated transport.
  Natalia Abuladze, Rustam Azimov, Debra K. Newman, Pakan Sassani, Weixin Liu, Sergei Tatishchev, Alexander Pushkin, Ira Kurtz> ;The Journal of Physiology. 2005 Jun 15
• 66 citations
  Molecular mechanism of kNBC1—carbonic anhydrase II interaction in proximal tubule cells
  Alexander Pushkin, Natalia Abuladze, Eitan Gross, Debra K. Newman, Sergei Tatishchev, Ivan Lee, Olga Fedotoff, Galyna Bondar, Rustam Azimov, Matt Ngyuen, Ira Kurtz> ;The Journal of Physiology. 2004 Aug 1
• 33 citations
  Expression and localization of rat NBC4c in liver and renal uroepithelium
  Natalia Abuladze, Alexander Pushkin, Sergei Tatishchev, Debra K. Newman, Pakan Sassani, Ira Kurtz> ;American Journal of Physiology. Cell Physiology. 2004 May 19
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